Other
UniProt agent skills for Claude Code, Codex and other agents.
- skills
- 65
- official
- 3
- Type
- Other
- Website
- uniprot.org
UniProt skills, ranked
Ranked by score. Sort bymost stars,trending,newest,recently updated
Official (3 skills)
| # | Skill | Repository | Stars | Used in | Tokens | Auto-check | Licence | Updated |
|---|---|---|---|---|---|---|---|---|
| 1 | A skill your agent uses when a researcher needs to query biomedical databases for biomarker discovery, build target profiles from UniProt/Open Targets/STRING, rank biomarker candidates by evidence… | aws-samples/ | 274 | — | ~1.1k | Automated safety check: Pass | MIT-0 | 5 days ago |
| 2 | A skill your agent uses when querying biomedical databases (UniProt, ClinVar, gnomAD, PDB, Reactome, Open Targets, etc.) via the Biomni AgentCore Gateway MCP server. | aws-samples/ | 274 | — | ~3.1k | Automated safety check: Pass | MIT-0 | 5 days ago |
| 3 | A skill your agent uses when a developer needs to conduct systematic literature searches, find research papers, extract content from publications, or build evidence summaries from biomedical… | aws-samples/ | 274 | — | ~1.1k | Automated safety check: Pass | MIT-0 | 5 days ago |
Community
| # | Skill | Repository | Stars | Used in | Tokens | Auto-check | Licence | Updated |
|---|---|---|---|---|---|---|---|---|
| 4 | Retrieve and analyze AlphaFold predicted structures for a protein. | google-deepmind/ | 3.2k | 2 repos | ~1.2k | Automated safety check: Pass | Apache-2.0 | 22 days ago |
| 5 | Toolkit for generating PowerToys release notes from GitHub milestone PRs or commit ranges. | smith-chem-wisc/ | 109 | — | ~1.4k | Automated safety check: Pass | MIT | today |
| 6 | Query 14+ biomedical databases for drug repurposing, target discovery, clinical trials, and literature research. | FreedomIntelligence/ | 3.1k | 1 repo | ~2.4k | Automated safety check: Pass | No licence | 2 mo ago |
| 7 | Workflow for fixing or changing RNAlysis code that talks to an EXTERNAL WEB SERVICE — UniProt, Ensembl, PANTHER, PhylomeDB, OrthoInspector, KEGG, or GO. | GuyTeichman/ | 140 | — | ~1.8k | Automated safety check: Pass | MIT | 8 days ago |
| 8 | Queries the UniProt REST API directly to search proteins, fetch FASTA sequences, map IDs between databases and read Swiss-Prot and TrEMBL entries. | davila7/ | 32k | 15 repos | ~1.7k | Automated safety check: Pass | MIT | today |
| 9 | 多源深度调研与专业报告生成。适用场景广泛——只要用户的问题涉及需要深度分析的专业话题,就应使用此技能。包括但不限于:(1) 用户明确要求调研/research/综述/报告/发现;(2) 用户提出一个技术或科学话题,话题复杂度需要多源深度分析;(3) 用户要求对比多种技术方案的优劣;(4) 涉及生物医药、蛋白质、基因、药物靶点等需要专业数据库支撑的问题。核心能力:根据问题性质自动组合 arXiv… | AgentTeam-TaichuAI/ | 670 | — | ~5.7k | Automated safety check: Pass | No licence | 5 mo ago |
| 10 | 10.Tooluniverse A skill your agent uses when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery. | ynulihao/ | 617 | 3 repos | ~2.5k | Automated safety check: Pass | No licence | 7 mo ago |
| 11 | 11.Bioservices Primary Python tool for 40+ bioinformatics services. An agent skill from davila7/claude-code-templates. | davila7/ | 32k | 11 repos | ~2.5k | Automated safety check: Pass | MIT | today |
| 12 | 12.Bio DB Tools Query public biology databases and APIs including UniProt, RCSB PDB, AlphaFold DB, ClinVar, dbSNP, gnomAD, Ensembl, GEO, InterPro, KEGG, OpenTargets, Reactome, and STRING. | DrugClaw/ | 125 | — | ~1.4k | Automated safety check: Pass | Apache-2.0 | 6 mo ago |
| 13 | 13.Gget CLI/Python toolkit for rapid bioinformatics queries. An agent skill from davila7/claude-code-templates. | davila7/ | 32k | 11 repos | ~6.3k | Automated safety check: Pass | MIT | today |
| 14 | Perform comprehensive gene enrichment and pathway analysis using gseapy (ORA and GSEA), PANTHER, STRING, Reactome, and 40+ ToolUniverse tools. | wu-yc/ | 1.1k | 2 repos | ~4k | Automated safety check: Pass | No licence | 6 mo ago |
| 15 | Access AlphaFold's 200M+ AI-predicted protein structures. An agent skill from davila7/claude-code-templates. | davila7/ | 32k | 10 repos | ~4k | Automated safety check: Pass | MIT | today |
| 16 | 16.Tooluniverse Access 1000+ scientific tools through ToolUniverse for drug discovery, protein analysis, genomics, literature search, clinical data, ADMET prediction, molecular docking, and more. | AgentTeam-TaichuAI/ | 670 | — | ~1.2k | Automated safety check: Pass | No licence | 5 mo ago |
| 17 | Query the DrugMechDB drug mechanism-of-action database. An agent skill from QSong-github/DrugClaw. | QSong-github/ | 116 | 1 repo | ~734 | Automated safety check: Pass | No licence | 1 mo ago |
| 18 | Access protein metadata, function, taxonomy, and sequences across UniProtKB, UniParc, and UniRef. | google-deepmind/ | 3.2k | 1 repo | ~3.1k | Automated safety check: Pass | Apache-2.0 | 22 days ago |
| 19 | Fetch a regional slice of plasma pQTL summary statistics from the UK Biobank Pharma Proteomics Project (UKB-PPP; Sun 2023 Nature) for a specific (protein, ancestry) measurement. | ClawBio/ | 1.2k | — | ~4.6k | Automated safety check: Pass | MIT | yesterday |
| 20 | Performs 3D structural searches of proteins against various databases (PDB, AlphaFold, CATH, MGnify, etc.) using the Foldseek API. | google-deepmind/ | 3.2k | 1 repo | ~1.3k | Automated safety check: Pass | Apache-2.0 | 22 days ago |
| 21 | Canonicalise antigen.gene and antigen.species in a VDJdb chunk against the epitope dictionary and the gene and species alias tables, detect spurious values (UniProt descriptions, "[species]"… | antigenomics/ | 157 | — | ~715 | Automated safety check: Pass | Unknown | today |
| 22 | 22.Foldseek Structure similarity search with Foldseek. An agent skill from adaptyvbio/protein-design-skills. | adaptyvbio/ | 163 | 4 repos | ~1.1k | Automated safety check: Pass | MIT | 3 mo ago |
| 23 | 23.Bioservices Provides a Python interface to bioinformatics services including UniProt, KEGG, ChEMBL, Reactome, QuickGO, and UniChem. | K-Dense-AI/ | 48k | 1 repo | ~3k | Automated safety check: Notes | MIT | 2 days ago |
| 24 | 24.Pdb Fetch and analyze protein structures from RCSB PDB. An agent skill from adaptyvbio/protein-design-skills. | adaptyvbio/ | 163 | 4 repos | ~1.4k | Automated safety check: Pass | MIT | 3 mo ago |
| 25 | Load when converting gene identifiers between Ensembl, Entrez, and HGNC symbol in a bulk RNA-seq count matrix. | TianGzlab/ | 161 | — | ~1k | Automated safety check: Pass | MIT | 2 mo ago |
| 26 | 26.Uniprot Access UniProt for protein sequence and annotation retrieval. | adaptyvbio/ | 163 | 2 repos | ~1.3k | Automated safety check: Pass | MIT | 3 mo ago |
| 27 | 27.Biopython Computational molecular biology library (sequence I/O, alignment, phylogenetics). | lamm-mit/ | 244 | — | ~3.9k | Automated safety check: Pass | Apache-2.0 | 1 mo ago |
| 28 | Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). | LeonChaoX/ | 937 | 2 repos | ~3k | Automated safety check: Pass | CC-BY-3.0 | 2 mo ago |
| 29 | Production-ready phylogenetics and sequence analysis skill for alignment processing, tree analysis, and evolutionary metrics. | wu-yc/ | 1.1k | 2 repos | ~4.2k | Automated safety check: Pass | No licence | 6 mo ago |
| 30 | Retrieves protein structure data from RCSB PDB, PDBe, and AlphaFold with protein disambiguation, quality assessment, and comprehensive structural profiles. | wu-yc/ | 1.1k | 2 repos | ~2.8k | Automated safety check: Pass | No licence | 6 mo ago |
| 31 | Production-ready RNA-seq differential expression analysis using PyDESeq2. | wu-yc/ | 1.1k | 2 repos | ~4.5k | Automated safety check: Pass | No licence | 6 mo ago |
| 32 | Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables. | GPTomics/ | 1.2k | 2 repos | ~3.2k | Automated safety check: Pass | MIT | 1 mo ago |
| 33 | Plot per-gene mutation distributions on a protein-domain map (lollipop / needle plots) showing mutation position, recurrence count, and variant classification with maftools, g3-lollipop… | GPTomics/ | 1.2k | 2 repos | ~3.1k | Automated safety check: Pass | MIT | 1 mo ago |
| 34 | Query UniProt's REST API (post-2022 endpoint at rest.uniprot.org) for protein sequences, annotations, GO terms, cross-references, ID mappings, and proteomes. | GPTomics/ | 1.2k | 2 repos | ~4.7k | Automated safety check: Pass | MIT | 1 mo ago |
| 35 | Conduct comprehensive literature research with target disambiguation, evidence grading, and structured theme extraction. | wu-yc/ | 1.1k | 2 repos | ~8.2k | Automated safety check: Pass | No licence | 6 mo ago |
| 36 | Gather comprehensive biological target intelligence from 9 parallel research paths covering protein info, structure, interactions, pathways, expression, variants, drug interactions, and literature. | wu-yc/ | 1.1k | 2 repos | ~13k | Automated safety check: Pass | No licence | 6 mo ago |
| 37 | Systematic clinical variant interpretation from raw variant calls to ACMG-classified recommendations with structural impact analysis. | wu-yc/ | 1.1k | 2 repos | ~9.5k | Automated safety check: Pass | No licence | 6 mo ago |
| 38 | Access and analyze AlphaFold protein structure predictions. An agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. | FreedomIntelligence/ | 3.1k | 1 repo | ~2.1k | Automated safety check: Pass | No licence | 2 mo ago |
| 39 | 39.Alphafold DB Access over 200M protein structures from AlphaFold DB; use when you need to retrieve predicted 3D structures (PDB/mmCIF), confidence metrics (pLDDT/PAE), or protein metadata by UniProt accession. | aipoch/ | 2k | — | ~606 | Automated safety check: Pass | MIT | 20 days ago |
| 40 | 40.Bioservices Unified Python access to 40+ bioinformatics web services; use when you need to query multiple databases (e.g., UniProt/KEGG/ChEMBL/Reactome) with one consistent API in a single workflow, especially… | aipoch/ | 2k | — | ~1.7k | Automated safety check: Pass | MIT | 20 days ago |
| 41 | 41.Gget Unified CLI/Python interface for querying genomic, proteomic, structure, and expression data across 20+ bioinformatics databases; use when you need fast, scriptable retrieval by gene/protein IDs or… | aipoch/ | 2k | — | ~816 | Automated safety check: Pass | MIT | 20 days ago |
| 42 | Direct REST API access to UniProt for protein search, entry retrieval, and identifier mapping; use when you need programmatic UniProtKB queries or cross-database ID conversion. | aipoch/ | 2k | — | ~1.3k | Automated safety check: Pass | MIT | 20 days ago |
| 43 | Retrieves and interprets AlphaFold Protein Structure Database (AFDB) models by UniProt accession, reading pLDDT and PAE confidence correctly. | GPTomics/ | 1.2k | 1 repo | ~4k | Automated safety check: Pass | MIT | 1 mo ago |
| 44 | Navigate the Bio.PDB SMCRA hierarchy (Structure-Model-Chain-Residue-Atom) safely, surfacing the heterogeneity it hides by default. | GPTomics/ | 1.2k | 1 repo | ~3.7k | Automated safety check: Pass | MIT | 1 mo ago |
| 45 | Query the BindingDB drug-target binding affinity database. An agent skill from QSong-github/DrugClaw. | QSong-github/ | 116 | 1 repo | ~648 | Automated safety check: Pass | No licence | 1 mo ago |
| 46 | Maps between gene identifier systems (Ensembl, Entrez, HGNC symbol, UniProt, RefSeq, MANE) using AnnotationDbi, biomaRt, mygene, pyensembl, and Ensembl REST. | GPTomics/ | 1.2k | 1 repo | ~6.4k | Automated safety check: Pass | MIT | 1 mo ago |
| 47 | Access AlphaFold DB's 200M+ predicted structures by UniProt ID. | jaechang-hits/ | 370 | 1 repo | ~4.1k | Automated safety check: Pass | CC-BY-4.0 | 8 days ago |
| 48 | Query EBI QuickGO REST API for GO terms and protein annotations. | jaechang-hits/ | 370 | 1 repo | ~6.9k | Automated safety check: Pass | Apache-2.0 | 8 days ago |
Questions, answered from the data.
What is the best UniProt skill?
Biomarker Database Analysis (official) from aws-samples/amazon-bedrock-agents-healthcare-lifesciences ranks first of the 65 UniProt skills listed here, with the highest score: its repository has 274 GitHub stars, its SKILL.md loads about 1.1k tokens and it passes the automated safety check with no findings. Next come Research Biomedical Databases and Research Deep Literature Review.
Is there an official UniProt skill?
3 of the 65 UniProt skills are official, published by the vendor's own GitHub organization: Biomarker Database Analysis, Research Biomedical Databases and Research Deep Literature Review.
How are these skills ranked?
By Skill Navigator score, which combines the GitHub stars of the skill's repository (shared across that repo's skills and discounted for large collections), how many other GitHub owners carry a copy of the skill, and automated SKILL.md quality checks, minus penalties for safety-check warnings and for each further skill from the same repository. Skills that fail the safety check are not listed.