Other

UniProt agent skills for Claude Code, Codex and other agents.

Comprehensive resource of protein sequences and functional annotation.
skills
65
official
3
Type
Other
Website
uniprot.org

UniProt skills, ranked

Ranked by score. Sort bymost stars,trending,newest,recently updated

Official (3 skills)

Official UniProt skills
#SkillRepositoryStarsUsed inTokensAuto-checkLicenceUpdated
1

A skill your agent uses when a researcher needs to query biomedical databases for biomarker discovery, build target profiles from UniProt/Open Targets/STRING, rank biomarker candidates by evidence…

aws-samples/amazon-bedrock-agents-healthcare-lifesciences274—~1.1kAutomated safety check: PassMIT-05 days ago
2

A skill your agent uses when querying biomedical databases (UniProt, ClinVar, gnomAD, PDB, Reactome, Open Targets, etc.) via the Biomni AgentCore Gateway MCP server.

aws-samples/amazon-bedrock-agents-healthcare-lifesciences274—~3.1kAutomated safety check: PassMIT-05 days ago
3

A skill your agent uses when a developer needs to conduct systematic literature searches, find research papers, extract content from publications, or build evidence summaries from biomedical…

aws-samples/amazon-bedrock-agents-healthcare-lifesciences274—~1.1kAutomated safety check: PassMIT-05 days ago

Community

Community UniProt skills
#SkillRepositoryStarsUsed inTokensAuto-checkLicenceUpdated
4

Retrieve and analyze AlphaFold predicted structures for a protein.

google-deepmind/science-skills3.2k2 repos~1.2kAutomated safety check: PassApache-2.022 days ago
5

Toolkit for generating PowerToys release notes from GitHub milestone PRs or commit ranges.

smith-chem-wisc/MetaMorpheus109—~1.4kAutomated safety check: PassMITtoday
6

Query 14+ biomedical databases for drug repurposing, target discovery, clinical trials, and literature research.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~2.4kAutomated safety check: PassNo licence2 mo ago
7

Workflow for fixing or changing RNAlysis code that talks to an EXTERNAL WEB SERVICE — UniProt, Ensembl, PANTHER, PhylomeDB, OrthoInspector, KEGG, or GO.

GuyTeichman/RNAlysis140—~1.8kAutomated safety check: PassMIT8 days ago
8

Queries the UniProt REST API directly to search proteins, fetch FASTA sequences, map IDs between databases and read Swiss-Prot and TrEMBL entries.

davila7/claude-code-templates32k15 repos~1.7kAutomated safety check: PassMITtoday
9

多源深度调研与专业报告生成。适用场景广泛——只要用户的问题涉及需要深度分析的专业话题,就应使用此技能。包括但不限于:(1) 用户明确要求调研/research/综述/报告/发现;(2) 用户提出一个技术或科学话题,话题复杂度需要多源深度分析;(3) 用户要求对比多种技术方案的优劣;(4) 涉及生物医药、蛋白质、基因、药物靶点等需要专业数据库支撑的问题。核心能力:根据问题性质自动组合 arXiv…

AgentTeam-TaichuAI/ScienceClaw670—~5.7kAutomated safety check: PassNo licence5 mo ago
10

A skill your agent uses when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery.

ynulihao/AgentSkillOS6173 repos~2.5kAutomated safety check: PassNo licence7 mo ago
11

Primary Python tool for 40+ bioinformatics services. An agent skill from davila7/claude-code-templates.

davila7/claude-code-templates32k11 repos~2.5kAutomated safety check: PassMITtoday
12

Query public biology databases and APIs including UniProt, RCSB PDB, AlphaFold DB, ClinVar, dbSNP, gnomAD, Ensembl, GEO, InterPro, KEGG, OpenTargets, Reactome, and STRING.

DrugClaw/DrugClaw125—~1.4kAutomated safety check: PassApache-2.06 mo ago
13
13.Gget

CLI/Python toolkit for rapid bioinformatics queries. An agent skill from davila7/claude-code-templates.

davila7/claude-code-templates32k11 repos~6.3kAutomated safety check: PassMITtoday
14

Perform comprehensive gene enrichment and pathway analysis using gseapy (ORA and GSEA), PANTHER, STRING, Reactome, and 40+ ToolUniverse tools.

wu-yc/LabClaw1.1k2 repos~4kAutomated safety check: PassNo licence6 mo ago
15

Access AlphaFold's 200M+ AI-predicted protein structures. An agent skill from davila7/claude-code-templates.

davila7/claude-code-templates32k10 repos~4kAutomated safety check: PassMITtoday
16

Access 1000+ scientific tools through ToolUniverse for drug discovery, protein analysis, genomics, literature search, clinical data, ADMET prediction, molecular docking, and more.

AgentTeam-TaichuAI/ScienceClaw670—~1.2kAutomated safety check: PassNo licence5 mo ago
17

Query the DrugMechDB drug mechanism-of-action database. An agent skill from QSong-github/DrugClaw.

QSong-github/DrugClaw1161 repo~734Automated safety check: PassNo licence1 mo ago
18

Access protein metadata, function, taxonomy, and sequences across UniProtKB, UniParc, and UniRef.

google-deepmind/science-skills3.2k1 repo~3.1kAutomated safety check: PassApache-2.022 days ago
19

Fetch a regional slice of plasma pQTL summary statistics from the UK Biobank Pharma Proteomics Project (UKB-PPP; Sun 2023 Nature) for a specific (protein, ancestry) measurement.

ClawBio/ClawBio1.2k—~4.6kAutomated safety check: PassMITyesterday
20

Performs 3D structural searches of proteins against various databases (PDB, AlphaFold, CATH, MGnify, etc.) using the Foldseek API.

google-deepmind/science-skills3.2k1 repo~1.3kAutomated safety check: PassApache-2.022 days ago
21

Canonicalise antigen.gene and antigen.species in a VDJdb chunk against the epitope dictionary and the gene and species alias tables, detect spurious values (UniProt descriptions, "[species]"…

antigenomics/vdjdb-db157—~715Automated safety check: PassUnknowntoday
22

Structure similarity search with Foldseek. An agent skill from adaptyvbio/protein-design-skills.

adaptyvbio/protein-design-skills1634 repos~1.1kAutomated safety check: PassMIT3 mo ago
23

Provides a Python interface to bioinformatics services including UniProt, KEGG, ChEMBL, Reactome, QuickGO, and UniChem.

K-Dense-AI/scientific-agent-skills48k1 repo~3kAutomated safety check: NotesMIT2 days ago
24
24.Pdb

Fetch and analyze protein structures from RCSB PDB. An agent skill from adaptyvbio/protein-design-skills.

adaptyvbio/protein-design-skills1634 repos~1.4kAutomated safety check: PassMIT3 mo ago
25

Load when converting gene identifiers between Ensembl, Entrez, and HGNC symbol in a bulk RNA-seq count matrix.

TianGzlab/OmicsClaw161—~1kAutomated safety check: PassMIT2 mo ago
26

Access UniProt for protein sequence and annotation retrieval.

adaptyvbio/protein-design-skills1632 repos~1.3kAutomated safety check: PassMIT3 mo ago
27

Computational molecular biology library (sequence I/O, alignment, phylogenetics).

lamm-mit/scienceclaw244—~3.9kAutomated safety check: PassApache-2.01 mo ago
28

Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50).

LeonChaoX/qinyan-academic-skills9372 repos~3kAutomated safety check: PassCC-BY-3.02 mo ago
29

Production-ready phylogenetics and sequence analysis skill for alignment processing, tree analysis, and evolutionary metrics.

wu-yc/LabClaw1.1k2 repos~4.2kAutomated safety check: PassNo licence6 mo ago
30

Retrieves protein structure data from RCSB PDB, PDBe, and AlphaFold with protein disambiguation, quality assessment, and comprehensive structural profiles.

wu-yc/LabClaw1.1k2 repos~2.8kAutomated safety check: PassNo licence6 mo ago
31

Production-ready RNA-seq differential expression analysis using PyDESeq2.

wu-yc/LabClaw1.1k2 repos~4.5kAutomated safety check: PassNo licence6 mo ago
32

Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables.

GPTomics/bioSkills1.2k2 repos~3.2kAutomated safety check: PassMIT1 mo ago
33

Plot per-gene mutation distributions on a protein-domain map (lollipop / needle plots) showing mutation position, recurrence count, and variant classification with maftools, g3-lollipop…

GPTomics/bioSkills1.2k2 repos~3.1kAutomated safety check: PassMIT1 mo ago
34

Query UniProt's REST API (post-2022 endpoint at rest.uniprot.org) for protein sequences, annotations, GO terms, cross-references, ID mappings, and proteomes.

GPTomics/bioSkills1.2k2 repos~4.7kAutomated safety check: PassMIT1 mo ago
35

Conduct comprehensive literature research with target disambiguation, evidence grading, and structured theme extraction.

wu-yc/LabClaw1.1k2 repos~8.2kAutomated safety check: PassNo licence6 mo ago
36

Gather comprehensive biological target intelligence from 9 parallel research paths covering protein info, structure, interactions, pathways, expression, variants, drug interactions, and literature.

wu-yc/LabClaw1.1k2 repos~13kAutomated safety check: PassNo licence6 mo ago
37

Systematic clinical variant interpretation from raw variant calls to ACMG-classified recommendations with structural impact analysis.

wu-yc/LabClaw1.1k2 repos~9.5kAutomated safety check: PassNo licence6 mo ago
38

Access and analyze AlphaFold protein structure predictions. An agent skill from FreedomIntelligence/OpenClaw-Medical-Skills.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~2.1kAutomated safety check: PassNo licence2 mo ago
39

Access over 200M protein structures from AlphaFold DB; use when you need to retrieve predicted 3D structures (PDB/mmCIF), confidence metrics (pLDDT/PAE), or protein metadata by UniProt accession.

aipoch/medical-research-skills2k—~606Automated safety check: PassMIT20 days ago
40

Unified Python access to 40+ bioinformatics web services; use when you need to query multiple databases (e.g., UniProt/KEGG/ChEMBL/Reactome) with one consistent API in a single workflow, especially…

aipoch/medical-research-skills2k—~1.7kAutomated safety check: PassMIT20 days ago
41
41.Gget

Unified CLI/Python interface for querying genomic, proteomic, structure, and expression data across 20+ bioinformatics databases; use when you need fast, scriptable retrieval by gene/protein IDs or…

aipoch/medical-research-skills2k—~816Automated safety check: PassMIT20 days ago
42

Direct REST API access to UniProt for protein search, entry retrieval, and identifier mapping; use when you need programmatic UniProtKB queries or cross-database ID conversion.

aipoch/medical-research-skills2k—~1.3kAutomated safety check: PassMIT20 days ago
43

Retrieves and interprets AlphaFold Protein Structure Database (AFDB) models by UniProt accession, reading pLDDT and PAE confidence correctly.

GPTomics/bioSkills1.2k1 repo~4kAutomated safety check: PassMIT1 mo ago
44

Navigate the Bio.PDB SMCRA hierarchy (Structure-Model-Chain-Residue-Atom) safely, surfacing the heterogeneity it hides by default.

GPTomics/bioSkills1.2k1 repo~3.7kAutomated safety check: PassMIT1 mo ago
45

Query the BindingDB drug-target binding affinity database. An agent skill from QSong-github/DrugClaw.

QSong-github/DrugClaw1161 repo~648Automated safety check: PassNo licence1 mo ago
46

Maps between gene identifier systems (Ensembl, Entrez, HGNC symbol, UniProt, RefSeq, MANE) using AnnotationDbi, biomaRt, mygene, pyensembl, and Ensembl REST.

GPTomics/bioSkills1.2k1 repo~6.4kAutomated safety check: PassMIT1 mo ago
47

Access AlphaFold DB's 200M+ predicted structures by UniProt ID.

jaechang-hits/SciAgent-Skills3701 repo~4.1kAutomated safety check: PassCC-BY-4.08 days ago
48

Query EBI QuickGO REST API for GO terms and protein annotations.

jaechang-hits/SciAgent-Skills3701 repo~6.9kAutomated safety check: PassApache-2.08 days ago

Questions, answered from the data.

What is the best UniProt skill?

Biomarker Database Analysis (official) from aws-samples/amazon-bedrock-agents-healthcare-lifesciences ranks first of the 65 UniProt skills listed here, with the highest score: its repository has 274 GitHub stars, its SKILL.md loads about 1.1k tokens and it passes the automated safety check with no findings. Next come Research Biomedical Databases and Research Deep Literature Review.

Is there an official UniProt skill?

3 of the 65 UniProt skills are official, published by the vendor's own GitHub organization: Biomarker Database Analysis, Research Biomedical Databases and Research Deep Literature Review.

How are these skills ranked?

By Skill Navigator score, which combines the GitHub stars of the skill's repository (shared across that repo's skills and discounted for large collections), how many other GitHub owners carry a copy of the skill, and automated SKILL.md quality checks, minus penalties for safety-check warnings and for each further skill from the same repository. Skills that fail the safety check are not listed.