Tooluniverse
ynulihao/AgentSkillOS
A skill your agent uses when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery.
Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50).
Install Bindingdb Database
$ npx skills add LeonChaoX/qinyan-academic-skills --skill bindingdb-database -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install LeonChaoX/qinyan-academic-skills bindingdb-database --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/LeonChaoX/qinyan-academic-skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/'skills/12-科学数据库/bindingdb-database' .claude/skills/bindingdb-database && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "bindingdb-database" agent skill from https://github.com/LeonChaoX/qinyan-academic-skills/tree/main/skills/12-%E7%A7%91%E5%AD%A6%E6%95%B0%E6%8D%AE%E5%BA%93/bindingdb-database into .claude/skills/bindingdb-database/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bindingdb-database", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/LeonChaoX/qinyan-academic-skills/tree/main/skills/12-%E7%A7%91%E5%AD%A6%E6%95%B0%E6%8D%AE%E5%BA%93/bindingdb-databaseType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add LeonChaoX/qinyan-academic-skills --skill bindingdb-database -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install LeonChaoX/qinyan-academic-skills bindingdb-database --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/LeonChaoX/qinyan-academic-skills.git skills-src && mkdir -p .agents/skills && cp -r skills-src/'skills/12-科学数据库/bindingdb-database' .agents/skills/bindingdb-database && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "bindingdb-database" agent skill from https://github.com/LeonChaoX/qinyan-academic-skills/tree/main/skills/12-%E7%A7%91%E5%AD%A6%E6%95%B0%E6%8D%AE%E5%BA%93/bindingdb-database into .agents/skills/bindingdb-database/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bindingdb-database", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add LeonChaoX/qinyan-academic-skills --skill bindingdb-database -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install LeonChaoX/qinyan-academic-skills bindingdb-database --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/LeonChaoX/qinyan-academic-skills.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/'skills/12-科学数据库/bindingdb-database' .cursor/skills/bindingdb-database && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "bindingdb-database" agent skill from https://github.com/LeonChaoX/qinyan-academic-skills/tree/main/skills/12-%E7%A7%91%E5%AD%A6%E6%95%B0%E6%8D%AE%E5%BA%93/bindingdb-database into .cursor/skills/bindingdb-database/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bindingdb-database", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/LeonChaoX/qinyan-academic-skills.git --path 'skills/12-科学数据库/bindingdb-database'--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add LeonChaoX/qinyan-academic-skills --skill bindingdb-database -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install LeonChaoX/qinyan-academic-skills bindingdb-database --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/LeonChaoX/qinyan-academic-skills.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/'skills/12-科学数据库/bindingdb-database' .gemini/skills/bindingdb-database && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "bindingdb-database" agent skill from https://github.com/LeonChaoX/qinyan-academic-skills/tree/main/skills/12-%E7%A7%91%E5%AD%A6%E6%95%B0%E6%8D%AE%E5%BA%93/bindingdb-database into .gemini/skills/bindingdb-database/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bindingdb-database", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install LeonChaoX/qinyan-academic-skills bindingdb-databaseInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add LeonChaoX/qinyan-academic-skills --skill bindingdb-database -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/LeonChaoX/qinyan-academic-skills.git skills-src && mkdir -p .github/skills && cp -r skills-src/'skills/12-科学数据库/bindingdb-database' .github/skills/bindingdb-database && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "bindingdb-database" agent skill from https://github.com/LeonChaoX/qinyan-academic-skills/tree/main/skills/12-%E7%A7%91%E5%AD%A6%E6%95%B0%E6%8D%AE%E5%BA%93/bindingdb-database into .github/skills/bindingdb-database/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bindingdb-database", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add LeonChaoX/qinyan-academic-skills --skill bindingdb-database -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install LeonChaoX/qinyan-academic-skills bindingdb-database --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/LeonChaoX/qinyan-academic-skills.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/'skills/12-科学数据库/bindingdb-database' .opencode/skills/bindingdb-database && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "bindingdb-database" agent skill from https://github.com/LeonChaoX/qinyan-academic-skills/tree/main/skills/12-%E7%A7%91%E5%AD%A6%E6%95%B0%E6%8D%AE%E5%BA%93/bindingdb-database into .opencode/skills/bindingdb-database/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bindingdb-database", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
Facts
- Skill name
bindingdb-database- GitHub stars
- 937
- Used in
- 2 other repos
- Token cost
- ~3k tokens
- SKILL.md length
- 479 words
- Files
- 2 (incl. references)
- Skills in repo
- 22
- Repo updated
- First seen
- Licence
- CC-BY-3.0
At a glance
Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50).
- Works in 6 steps: BindingDB REST API → Query by Target (UniProt ID) → Query by Compound Name or SMILES → …
- Tasks that involve Drug discovery and cheminformatics
- SKILL.md covers Overview, When to Use This Skill, Core Capabilities and Query Workflows, plus 4 more sections
- Reaches bindingdb.org
What it does
Bindingdb Database is an agent skill from LeonChaoX/qinyan-academic-skills. Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Search by target (UniProt ID), compound (SMILES/name), or pathogen. Essential for drug discovery, lead optimization, polypharmacology analysis, and structure-activity relationship (SAR) studies.
Its SKILL.md is about 3k tokens, which your agent loads only when the skill is triggered. The skill folder holds 2 other files, including reference files (for example `references/affinity_queries.md`).
It sits in Research & Science, covering Drug discovery and cheminformatics. It works with UniProt. The repository describes itself as: A curated, multilingual library of 182 installable AI agent skills for end-to-end academic research—spanning literature discovery, scientific writing, grant development…
When your agent uses it
- Tasks that involve Drug discovery and cheminformatics
Example prompts
- “/bindingdb-database”
Requirements
- Python 3
Workflow steps
6 steps, taken from the step headings in SKILL.md.
- BindingDB REST API
- Query by Target (UniProt ID)
- Query by Compound Name or SMILES
- Download-Based Analysis (Recommended for Large Queries)
- SAR Analysis
- Polypharmacology Profile
What it can do on your machine
Read from SKILL.md and the folder at commit df5a498. It shows what the files ask for, not the result of running them.
Tool permissions
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Runs code
No scripts in the folder and no shell commands in SKILL.md (its code samples are python).
From the folder's file list and the shell code blocks in SKILL.md.
Network
Hosts in commands or code, which the agent is likely to contact:
bindingdb.org
Also links to:
github.comebi.ac.uk
From URLs in SKILL.md, links to its own repository left out.
Credentials
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
Context cost
Bindingdb Database loads about 3k tokens when it runs, and up to ~4.5k if it reads all its reference files. Until then it costs about 74 tokens; SKILL.md has 479 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
Safety
Auto-check passed
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.
SKILL.md
Its licence (CC-BY-3.0) doesn't allow us to republish the file, so here is its outline and opening line. It has 479 words (~3,016 tokens).
“BindingDB (https://www.bindingdb.org/) is the primary public database of measured drug-protein binding affinities. It contains over 3 million binding data records for ~1.4 million compounds tested against ~9,200 protein targets, curated from scientific literature and patent literature. BindingDB stores quantitative binding…”
- name
- bindingdb-database
- license
- CC-BY-3.0
- metadata.skill-author
- Kuan-lin Huang
Files
SKILL.md and 1 other file (references) in skills/12-科学数据库/bindingdb-database of LeonChaoX/qinyan-academic-skills.
- SKILL.md
- references/affinity_queries.md
Open the folder on GitHubat commit df5a498
Used in 2 other repositories
We found 2 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 2 other GitHub owners. This page covers the copy in LeonChaoX/qinyan-academic-skills, which our catalogue first saw on October 7, 2026.
Compare with similar skills
Bindingdb Database next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| Bindingdb Database this skillLeonChaoX/qinyan-academic-skills | 937 | 2 repos | ~3k | Automated safety check: Pass | CC-BY-3.0 | |
| Tooluniverseynulihao/AgentSkillOS | 617 | 3 repos | ~2.5k | Automated safety check: Pass | None | |
| TooluniverseAgentTeam-TaichuAI/ScienceClaw | 670 | — | ~1.2k | Automated safety check: Pass | None | |
| Bindingdb QueryQSong-github/DrugClaw | 116 | 1 repos | ~648 | Automated safety check: Pass | None | |
| Gtopdb Databasejaechang-hits/SciAgent-Skills | 370 | 1 repos | ~4.9k | Automated safety check: Pass | Custom licence | |
| Pdb Databasejaechang-hits/SciAgent-Skills | 370 | 1 repos | ~7.7k | Automated safety check: Pass | BSD-3-Clause |
Similar skills
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Bindingdb Query
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Query the BindingDB drug-target binding affinity database. An agent skill from QSong-github/DrugClaw.
Gtopdb Database
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Alphafold Database Fetch And Analyze
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Works with
Categories
Questions about Bindingdb Database
What does Bindingdb Database do?
Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Bindingdb Database is an agent skill from LeonChaoX/qinyan-academic-skills. Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50).
When should I use Bindingdb Database?
Bindingdb Database fits situations like: tasks that involve Drug discovery and cheminformatics.
How do I install Bindingdb Database in Claude Code?
Run `npx skills add LeonChaoX/qinyan-academic-skills --skill bindingdb-database -a claude-code`. Or copy the skill folder (skills/12-科学数据库/bindingdb-database in LeonChaoX/qinyan-academic-skills) into .claude/skills/bindingdb-database in your project. Claude Code loads it when a task matches its description.
How do I install Bindingdb Database in Codex?
Run `npx skills add LeonChaoX/qinyan-academic-skills --skill bindingdb-database -a codex`. Or copy the skill folder (skills/12-科学数据库/bindingdb-database in LeonChaoX/qinyan-academic-skills) into .agents/skills/bindingdb-database in your project. Codex loads it when a task matches its description.
Can I use Bindingdb Database in Cursor, Gemini CLI or GitHub Copilot?
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add LeonChaoX/qinyan-academic-skills --skill bindingdb-database -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bindingdb-database, .gemini/skills/bindingdb-database, .github/skills/bindingdb-database and .opencode/skills/bindingdb-database in your project.
What does Bindingdb Database need to run?
SKILL.md names no scripts, command-line tools or credentials: Bindingdb Database is instructions for the agent only. Our summary lists: Python 3.
Does Bindingdb Database access the network?
SKILL.md names 3 domains. In commands or code: bindingdb.org; the agent is likely to contact it when it follows the instructions. As links in the text: github.com and ebi.ac.uk. This is read from the text; nothing was executed.
Is Bindingdb Database safe to install?
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.
What licence does Bindingdb Database use?
Bindingdb Database is published under the CC-BY-3.0 licence (declared in SKILL.md).
How many tokens does Bindingdb Database use?
About 3k tokens (SKILL.md is roughly 12k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 1.5k tokens, read only when the agent opens those files.
What are the alternatives to Bindingdb Database?
Skills that share tags, products or a category with Bindingdb Database: Tooluniverse (ynulihao/AgentSkillOS, 617 stars), Tooluniverse (AgentTeam-TaichuAI/ScienceClaw, 670 stars), Bindingdb Query (QSong-github/DrugClaw, 116 stars) and Gtopdb Database (jaechang-hits/SciAgent-Skills, 370 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
Who maintains Bindingdb Database?
LeonChaoX (a GitHub user) maintains it in LeonChaoX/qinyan-academic-skills, which has 937 GitHub stars. The repository holds 22 skills in this directory. The repository was last updated on July 20, 2026.
Source: LeonChaoX/qinyan-academic-skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.