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Ensembl agent skills for Claude Code, Codex and other agents.
- skills
- 49
- Type
- Other
- Website
- ensembl.org
- Official GitHub
- Ensembl
Ensembl skills, ranked
Ranked by score. Sort bymost stars,trending,newest,recently updated
| # | Skill | Repository | Stars | Used in | Tokens | Auto-check | Licence | Updated |
|---|---|---|---|---|---|---|---|---|
| 1 | A skill your agent uses when you want to retrieve semi-quantitative protein expression and spatial localisation data from the Human Protein Atlas (HPA). | google-deepmind/ | 3.2k | 2 repos | ~1.6k | Automated safety check: Pass | Apache-2.0 | 22 days ago |
| 2 | Workflow for fixing or changing RNAlysis code that talks to an EXTERNAL WEB SERVICE — UniProt, Ensembl, PANTHER, PhylomeDB, OrthoInspector, KEGG, or GO. | GuyTeichman/ | 140 | — | ~1.8k | Automated safety check: Pass | MIT | 9 days ago |
| 3 | Query Ensembl genome database REST API for 250+ species. An agent skill from davila7/claude-code-templates. | davila7/ | 32k | 10 repos | ~2.1k | Automated safety check: Pass | MIT | today |
| 4 | Query public biology databases and APIs including UniProt, RCSB PDB, AlphaFold DB, ClinVar, dbSNP, gnomAD, Ensembl, GEO, InterPro, KEGG, OpenTargets, Reactome, and STRING. | DrugClaw/ | 125 | — | ~1.4k | Automated safety check: Pass | Apache-2.0 | 6 mo ago |
| 5 | Annotates VCF variants and normalizes HGVS nomenclature with public, license-free annotators (Ensembl VEP REST, VEP/SnpEff/ANNOVAR offline) and links variants to gnomAD population frequencies and… | maziyarpanahi/ | 5.5k | — | ~2.1k | Automated safety check: Pass | Apache-2.0 | yesterday |
| 6 | 6.Gget CLI/Python toolkit for rapid bioinformatics queries. An agent skill from davila7/claude-code-templates. | davila7/ | 32k | 11 repos | ~6.3k | Automated safety check: Pass | MIT | today |
| 7 | Perform comprehensive gene enrichment and pathway analysis using gseapy (ORA and GSEA), PANTHER, STRING, Reactome, and 40+ ToolUniverse tools. | wu-yc/ | 1.1k | 2 repos | ~4k | Automated safety check: Pass | No licence | 6 mo ago |
| 8 | Query the Ensembl database to resolve gene, transcript, and protein IDs, fetch genomic or protein sequences, retrieve gene structures (exons), and get variant consequence and effect predictions (VEP). | google-deepmind/ | 3.2k | 1 repo | ~2.2k | Automated safety check: Pass | Apache-2.0 | 22 days ago |
| 9 | Query the Open Targets Platform for drug-target-disease associations. | QSong-github/ | 116 | 1 repo | ~601 | Automated safety check: Pass | No licence | 1 mo ago |
| 10 | gget CLI and Python workflow for quick genomic database queries, sequence lookup, BLAST-style searches, enrichment checks, and reproducible bioinformatics evidence logs. | affaan-m/ | 274k | 1 repo | ~1.3k | Automated safety check: Pass | MIT | 2 days ago |
| 11 | Load when converting gene identifiers between Ensembl, Entrez, and HGNC symbol in a bulk RNA-seq count matrix. | TianGzlab/ | 161 | — | ~1k | Automated safety check: Pass | MIT | 2 mo ago |
| 12 | Annotate VCF variants with Ensembl VEP REST, ClinVar significance, gnomAD/population frequency context, and prioritized variant ranking. | ClawBio/ | 1.2k | 1 repo | ~2.8k | Automated safety check: Pass | MIT | yesterday |
| 13 | Annotate VCF variants with Ensembl VEP, ClinVar, and gnomAD. | ClawBio/ | 1.2k | 1 repo | ~2.4k | Automated safety check: Pass | MIT | yesterday |
| 14 | Production-ready phylogenetics and sequence analysis skill for alignment processing, tree analysis, and evolutionary metrics. | wu-yc/ | 1.1k | 2 repos | ~4.2k | Automated safety check: Pass | No licence | 6 mo ago |
| 15 | Production-ready RNA-seq differential expression analysis using PyDESeq2. | wu-yc/ | 1.1k | 2 repos | ~4.5k | Automated safety check: Pass | No licence | 6 mo ago |
| 16 | ゲノムデータベースへのクイック検索、配列検索、BLAST スタイルの検索、エンリッチメントチェック、および再現可能なバイオインフォマティクス証拠ログのための gget CLI および Python ワークフロー。 | affaan-m/ | 274k | — | ~870 | Automated safety check: Pass | MIT | 2 days ago |
| 17 | In recent years a wealth of biological data has become available in public data repositories. | bioMate-AI/ | 804 | — | ~4.5k | Automated safety check: Pass | Unknown | 3 mo ago |
| 18 | Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables. | GPTomics/ | 1.2k | 2 repos | ~3.2k | Automated safety check: Pass | MIT | 1 mo ago |
| 19 | Query the Ensembl REST API for gene/transcript/protein lookup, sequence retrieval, comparative genomics (Compara), variant effect prediction (VEP), regulatory features, and cross-species… | GPTomics/ | 1.2k | 2 repos | ~3.6k | Automated safety check: Pass | MIT | 1 mo ago |
| 20 | Pull pre-computed ortholog calls from public databases (OrthoDB, Ensembl Compara, OMA browser, eggNOG, PANTHER, KEGG Orthology, HomoloGene) via their REST APIs. | GPTomics/ | 1.2k | 2 repos | ~4.6k | Automated safety check: Pass | MIT | 1 mo ago |
| 21 | Production-ready genomics and epigenomics data processing for BixBench questions. | wu-yc/ | 1.1k | 2 repos | ~14k | Automated safety check: Pass | No licence | 6 mo ago |
| 22 | Conduct comprehensive literature research with target disambiguation, evidence grading, and structured theme extraction. | wu-yc/ | 1.1k | 2 repos | ~8.2k | Automated safety check: Pass | No licence | 6 mo ago |
| 23 | Gather comprehensive biological target intelligence from 9 parallel research paths covering protein info, structure, interactions, pathways, expression, variants, drug interactions, and literature. | wu-yc/ | 1.1k | 2 repos | ~13k | Automated safety check: Pass | No licence | 6 mo ago |
| 24 | Detects somatic mutations in circulating tumor DNA using variant callers optimized for low allele fractions with UMI-based error suppression. | FreedomIntelligence/ | 3.1k | 1 repo | ~1.7k | Automated safety check: Pass | No licence | 2 mo ago |
| 25 | NCBI Gene via E-utilities: curated records across 1M+ taxa. An agent skill from jaechang-hits/SciAgent-Skills. | jaechang-hits/ | 370 | 1 repo | ~4.4k | Automated safety check: Pass | CC0-1.0 | 8 days ago |
| 26 | Access Ensembl REST API for vertebrate genomic data; use when you need gene/ID lookups, sequence retrieval, variant effect prediction (VEP), or homology/assembly coordinate mapping. | aipoch/ | 2k | — | ~1.5k | Automated safety check: Pass | MIT | 20 days ago |
| 27 | 27.Gget Unified CLI/Python interface for querying genomic, proteomic, structure, and expression data across 20+ bioinformatics databases; use when you need fast, scriptable retrieval by gene/protein IDs or… | aipoch/ | 2k | — | ~816 | Automated safety check: Pass | MIT | 20 days ago |
| 28 | Tests a gene list (ORA, enrichWP) or a ranked gene vector (GSEA, gseWP) against the WikiPathways community-curated pathway collection with clusterProfiler and rWikiPathways. | GPTomics/ | 1.2k | 1 repo | ~4.5k | Automated safety check: Pass | MIT | 1 mo ago |
| 29 | Orchestrates the end-to-end single-cell RNA-seq pipeline from 10x Cell Ranger output to annotated cell types, chaining ambient-RNA removal, doublet detection, MAD-adaptive QC, normalization… | GPTomics/ | 1.2k | 1 repo | ~5.1k | Automated safety check: Pass | MIT | 1 mo ago |
| 30 | Unified CLI/Python interface to 20+ genomic databases. An agent skill from jaechang-hits/SciAgent-Skills. | jaechang-hits/ | 370 | 2 repos | ~5.3k | Automated safety check: Pass | BSD-2-Clause | 8 days ago |
| 31 | 31.Gene Info Retrieves comprehensive gene information including PubMed publication counts, NCBI summaries, and Ensembl transcript data. | aipoch/ | 2k | — | ~2.3k | Automated safety check: Pass | MIT | 20 days ago |
| 32 | Maps between gene identifier systems (Ensembl, Entrez, HGNC symbol, UniProt, RefSeq, MANE) using AnnotationDbi, biomaRt, mygene, pyensembl, and Ensembl REST. | GPTomics/ | 1.2k | 1 repo | ~6.4k | Automated safety check: Pass | MIT | 1 mo ago |
| 33 | Tests gene lists, ranked vectors, and fold-change vectors against KEGG pathways and modules with clusterProfiler enrichKEGG/enrichMKEGG (ORA), gseKEGG (GSEA), and SPIA/graphite (signed-topology… | GPTomics/ | 1.2k | 1 repo | ~5.4k | Automated safety check: Pass | MIT | 1 mo ago |
| 34 | Annotates VCF variants with functional consequences, population frequencies, and pathogenicity scores using bcftools annotate/csq, Ensembl VEP, SnpEff, and ANNOVAR. | GPTomics/ | 1.2k | 1 repo | ~6.4k | Automated safety check: Pass | MIT | 1 mo ago |
| 35 | Query the Open Targets Platform to retrieve targets, diseases, or evidence records when you need target-disease association data and evidence-based scores for therapeutic discovery. | aipoch/ | 2k | — | ~1.6k | Automated safety check: Pass | MIT | 20 days ago |
| 36 | Retrieve mouse phenotype data from the Jackson Laboratory Mouse Phenome Database (MPD) via its REST API. | jaechang-hits/ | 370 | 1 repo | ~6.8k | Automated safety check: Pass | CC-BY-4.0 | 8 days ago |
| 37 | Query UCSC Genome Browser REST API for DNA sequences, tracks, gene models, and conservation across 100+ assemblies. | jaechang-hits/ | 370 | 1 repo | ~6k | Automated safety check: Pass | Apache-2.0 | 8 days ago |
| 38 | Query the NCI CCDI Molecular Targets Platform (pediatric oncology) for targets (genes), diseases, drugs, and target-disease associations via its public GraphQL API. | QSong-github/ | 116 | 1 repo | ~744 | Automated safety check: Pass | No licence | 1 mo ago |
| 39 | Unified Python interface to 40+ bioinformatics web services: UniProt proteins, KEGG pathways, ChEMBL/ChEBI/PubChem, BLAST, cross-database ID mapping, GO annotations, PPI. | jaechang-hits/ | 370 | 1 repo | ~6.1k | Automated safety check: Pass | Unknown | 8 days ago |
| 40 | Query NCBI ClinVar via E-utilities for variant clinical significance, pathogenicity, disease associations. | jaechang-hits/ | 370 | 1 repo | ~4.9k | Automated safety check: Pass | CC0-1.0 | 8 days ago |
| 41 | Ensembl REST API for gene/transcript/variant annotations in 300+ species. | jaechang-hits/ | 370 | 1 repo | ~4k | Automated safety check: Pass | Apache-2.0 | 8 days ago |
| 42 | Query UniProt REST API: search by gene/protein name, fetch FASTA, map IDs (Ensembl, PDB, RefSeq), access Swiss-Prot annotations. | jaechang-hits/ | 370 | 1 repo | ~3.4k | Automated safety check: Pass | CC-BY-4.0 | 8 days ago |
| 43 | Query gene, sequence, and variant data via the Ensembl REST API | wentorai/ | 298 | 1 repo | ~2k | Automated safety check: Pass | MIT | 3 mo ago |
| 44 | Retrieve genomic sequences from Ensembl database using transcript or gene IDs to obtain nucleotide and protein sequences. | InternScience/ | 169 | 1 repo | ~746 | Automated safety check: Pass | MIT | 4 mo ago |
| 45 | Annotate and filter VCF variants with SnpEff and SnpSift. An agent skill from jaechang-hits/SciAgent-Skills. | jaechang-hits/ | 370 | 1 repo | ~5.4k | Automated safety check: Pass | MIT | 8 days ago |
| 46 | Search 78 public scientific, biomedical, materials science, and economic databases via REST APIs. | majiayu000/ | 666 | 1 repo | ~7k | Automated safety check: Notes | MIT | today |
| 47 | 24 biomedical research skills. An agent skill from wentorai/research-plugins. | wentorai/ | 298 | 1 repo | ~827 | Automated safety check: Pass | MIT | 3 mo ago |
| 48 | Provides utilities for identifying drug-target interactions for sets of small molecule or gene/protein identifiers. | bioMate-AI/ | 804 | — | ~1.2k | Automated safety check: Pass | Unknown | 3 mo ago |
Questions, answered from the data.
What is the best Ensembl skill?
Human Protein Atlas Database from google-deepmind/science-skills ranks first of the 49 Ensembl skills listed here, with the highest score: its repository has 3.2k GitHub stars, 2 other GitHub owners carry a copy, its SKILL.md loads about 1.6k tokens and it passes the automated safety check with no findings. Next come External API Change and Ensembl Database.
Is there an official Ensembl skill?
None yet. All 49 Ensembl skills listed here come from community repositories; a skill counts as official when the product's own GitHub organization publishes it.
How are these skills ranked?
By Skill Navigator score, which combines the GitHub stars of the skill's repository (shared across that repo's skills and discounted for large collections), how many other GitHub owners carry a copy of the skill, and automated SKILL.md quality checks, minus penalties for safety-check warnings and for each further skill from the same repository. Skills that fail the safety check are not listed.