Agent skill

Tooluniverse

by ynulihao in ynulihao/AgentSkillOS

A skill your agent uses when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery.

No licenceAuto-check passedResearch & Science

Install Tooluniverse

skills CLI
$ npx skills add ynulihao/AgentSkillOS --skill tooluniverse -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install ynulihao/AgentSkillOS tooluniverse --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/ynulihao/AgentSkillOS.git skills-src && mkdir -p .claude/skills && cp -r skills-src/data/skill_seeds/tooluniverse .claude/skills/tooluniverse && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
tooluniverse
GitHub stars
617
Used in
3 other repos
Token cost
~2.5k tokens
SKILL.md length
747 words
Files
1
Skills in repo
26
Repo updated
First seen
Licence
None found

At a glance

A skill your agent uses when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery.

  • Works in 3 steps: Tool Discovery → Tool Execution → Tool Composition and Workflows
  • Working with scientific research tools and workflows across bioinformatics
  • SKILL.md covers Overview, When to Use This Skill, Quick Start and Core Workflows, plus 6 more sections
  • Calls uv

What it does

Tooluniverse is an agent skill from ynulihao/AgentSkillOS. Use this skill when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery. This skill provides access to 600+ scientific tools including machine learning models, datasets, APIs, and analysis packages. Use when searching for scientific tools, executing computational biology workflows, composing multi-step research pipelines, accessing databases like OpenTargets/PubChem/UniProt/PDB/ChEMBL, performing tool discovery…

Its SKILL.md is about 2.5k tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.

It sits in Research & Science, covering Bioinformatics, Drug discovery and cheminformatics and Protein structure and design. It works with UniProt and Model Context Protocol. The repository describes itself as: Build your agent from 200,000+ skills via skill RETRIEVAL & ORCHESTRATION.

When your agent uses it

  • Working with scientific research tools and workflows across bioinformatics
  • Cheminformatics
  • Structural biology
  • Searching for scientific tools

Example prompts

  • “/tooluniverse”

Requirements

  • Python 3

Workflow steps

3 steps, taken from the step headings in SKILL.md.

  1. Tool Discovery
  2. Tool Execution
  3. Tool Composition and Workflows

What it can do on your machine

Read from SKILL.md and the folder at commit c3cfae1. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Shell commands in SKILL.md call:

    • uv

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    Links to these hosts (documentation or services it may open):

    • aiscientist.tools
    • github.com
    • zitniklab.hms.harvard.edu

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Tooluniverse loads about 2.5k tokens when it runs. Until then it costs about 155 tokens; SKILL.md has 747 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~155
When it runs · the whole SKILL.md, loaded when a task matches
~2.5k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 747 words (~2,498 tokens).

“ToolUniverse is a unified ecosystem that enables AI agents to function as research scientists by providing standardized access to 600+ scientific resources. Use this skill to discover, execute, and compose scientific tools across multiple research domains including bioinformatics, cheminformatics, genomics…”

— opening of SKILL.md by ynulihao
name
tooluniverse

Read the full SKILL.md on GitHub

Files

Just SKILL.md in data/skill_seeds/tooluniverse of ynulihao/AgentSkillOS.

Open the folder on GitHubat commit c3cfae1

Used in 3 other repositories

We found 12 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 3 other GitHub owners. This page covers the copy in ynulihao/AgentSkillOS, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Tooluniverse next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Tooluniverse compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Tooluniverse this skillynulihao/AgentSkillOS6173 repos~2.5kAutomated safety check: PassNone
Hcls Build Agentaws-samples/amazon-bedrock-agents-healthcare-lifesciences274—~885Automated safety check: PassMIT-0
Ggetdavila7/claude-code-templates32k11 repos~6.3kAutomated safety check: PassMIT
TooluniverseAgentTeam-TaichuAI/ScienceClaw670—~1.2kAutomated safety check: PassNone
Hcls Get Startedaws-samples/amazon-bedrock-agents-healthcare-lifesciences274—~607Automated safety check: PassMIT-0
Research Biomedical Databasesaws-samples/amazon-bedrock-agents-healthcare-lifesciences274—~3.1kAutomated safety check: PassMIT-0

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Questions about Tooluniverse

What does Tooluniverse do?

A skill your agent uses when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery. Tooluniverse is an agent skill from ynulihao/AgentSkillOS. Use this skill when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery.

When should I use Tooluniverse?

Tooluniverse fits situations like: working with scientific research tools and workflows across bioinformatics; cheminformatics; structural biology; searching for scientific tools.

How do I install Tooluniverse in Claude Code?

Run `npx skills add ynulihao/AgentSkillOS --skill tooluniverse -a claude-code`. Or copy the skill folder (data/skill_seeds/tooluniverse in ynulihao/AgentSkillOS) into .claude/skills/tooluniverse in your project. Claude Code loads it when a task matches its description.

How do I install Tooluniverse in Codex?

Run `npx skills add ynulihao/AgentSkillOS --skill tooluniverse -a codex`. Or copy the skill folder (data/skill_seeds/tooluniverse in ynulihao/AgentSkillOS) into .agents/skills/tooluniverse in your project. Codex loads it when a task matches its description.

Can I use Tooluniverse in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add ynulihao/AgentSkillOS --skill tooluniverse -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/tooluniverse, .gemini/skills/tooluniverse, .github/skills/tooluniverse and .opencode/skills/tooluniverse in your project.

What does Tooluniverse need to run?

Going by SKILL.md and its folder, Tooluniverse needs the command-line tools its instructions call (uv). Our summary lists: Python 3.

Does Tooluniverse access the network?

SKILL.md names 3 domains. As links in the text: aiscientist.tools, github.com and zitniklab.hms.harvard.edu. This is read from the text; nothing was executed.

Is Tooluniverse safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Tooluniverse use?

No licence was found for Tooluniverse or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Tooluniverse use?

About 2.5k tokens (SKILL.md is roughly 10k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Tooluniverse?

Skills that share tags, products or a category with Tooluniverse: Hcls Build Agent (aws-samples/amazon-bedrock-agents-healthcare-lifesciences, 274 stars), Gget (davila7/claude-code-templates, 32k stars), Tooluniverse (AgentTeam-TaichuAI/ScienceClaw, 670 stars) and Hcls Get Started (aws-samples/amazon-bedrock-agents-healthcare-lifesciences, 274 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Tooluniverse?

ynulihao (a GitHub user) maintains it in ynulihao/AgentSkillOS, which has 617 GitHub stars. The repository holds 26 skills in this directory. The repository was last updated on March 7, 2026.

Source: ynulihao/AgentSkillOS on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.