Library

Biopython agent skills for Claude Code, Codex and other agents.

Python tools for computational biology and bioinformatics, including sequence parsing and BLAST.
skills
71
Type
Library
Website
biopython.org
Official GitHub
biopython

Biopython skills, ranked

Ranked by score. Sort bymost stars,trending,newest,recently updated

Biopython skills, ranked
#SkillRepositoryStarsUsed inTokensAuto-checkLicenceUpdated
1

Read, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO.

GPTomics/bioSkills1.2k3 repos~4.9kAutomated safety check: PassMIT1 mo ago
2

Quick reference for Biopython work: sequence operations, SeqIO file parsing, BLAST searches, Entrez queries, phylogenetic trees and PDB structure analysis.

aiming-lab/AutoResearchClaw15k—~810Automated safety check: PassMIT1 mo ago
3

Write biological sequences to files (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO.

GPTomics/bioSkills1.2k3 repos~2.1kAutomated safety check: PassMIT1 mo ago
4

Primary Python toolkit for molecular biology. An agent skill from davila7/claude-code-templates.

davila7/claude-code-templates32k13 repos~3.4kAutomated safety check: PassMITtoday
5

CLI/Python toolkit for rapid bioinformatics queries. An agent skill from davila7/claude-code-templates.

davila7/claude-code-templates32k11 repos~6.3kAutomated safety check: PassMITtoday
6

Perform pairwise sequence alignment using Biopython Bio.Align.PairwiseAligner.

majiayu000/claude-skill-registry6664 repos~1.7kAutomated safety check: PassMITtoday
7

Queries 20+ bioinformatics resources through CLI/Python. An agent skill from K-Dense-AI/scientific-agent-skills.

K-Dense-AI/scientific-agent-skills48k1 repo~2.8kAutomated safety check: NotesBSD-2-Clause2 days ago
8

Provides Biopython workflows for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez).

K-Dense-AI/scientific-agent-skills48k1 repo~4.3kAutomated safety check: NotesMIT2 days ago
9

Computational molecular biology library (sequence I/O, alignment, phylogenetics).

lamm-mit/scienceclaw244—~3.9kAutomated safety check: PassApache-2.01 mo ago
10

Analyze a single FASTA file (nucleotide or protein), compute sequence-level metrics (GC, ORFs, MW, pI, GRAVY, secondary-structure fractions) with Biopython, and write a Markdown report plus…

ClawBio/ClawBio1.2k1 repo~3.4kAutomated safety check: PassMITyesterday
11

Production-ready phylogenetics and sequence analysis skill for alignment processing, tree analysis, and evolutionary metrics.

wu-yc/LabClaw1.1k2 repos~4.2kAutomated safety check: PassNo licence6 mo ago
12

Download large datasets from NCBI efficiently using EPost, history server, batching, rate limiting, and retry logic.

GPTomics/bioSkills1.2k2 repos~3.9kAutomated safety check: PassMIT1 mo ago
13

Run remote BLAST searches against NCBI servers using Biopython Bio.Blast.NCBIWWW.

GPTomics/bioSkills1.2k2 repos~3.9kAutomated safety check: PassMIT1 mo ago
14

Retrieve records from NCBI databases using Biopython Bio.Entrez (EFetch, ESummary).

GPTomics/bioSkills1.2k2 repos~3.7kAutomated safety check: PassMIT1 mo ago
15

Find cross-database references between NCBI databases using Biopython Bio.Entrez (ELink).

GPTomics/bioSkills1.2k2 repos~3.8kAutomated safety check: PassMIT1 mo ago
16

Process multiple sequence files in batch using Biopython. An agent skill from FreedomIntelligence/OpenClaw-Medical-Skills.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~2.2kAutomated safety check: PassNo licence2 mo ago
17

Read and write compressed sequence files (gzip, bzip2, BGZF) using Biopython.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~2kAutomated safety check: PassNo licence2 mo ago
18

Filter and select sequences by criteria (length, ID, GC content, patterns) using Biopython.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~1.9kAutomated safety check: PassNo licence2 mo ago
19

Convert between sequence file formats (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~1.5kAutomated safety check: PassNo licence2 mo ago
20

Handle paired-end FASTQ files (R1/R2) using Biopython. An agent skill from FreedomIntelligence/OpenClaw-Medical-Skills.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~2.6kAutomated safety check: PassNo licence2 mo ago
21

Perform geometric calculations on protein structures using Biopython Bio.PDB.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~3.2kAutomated safety check: PassNo licence2 mo ago
22

Parse and write protein structure files using Biopython Bio.PDB.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~1.9kAutomated safety check: PassNo licence2 mo ago
23

Modify protein structures using Biopython Bio.PDB. An agent skill from FreedomIntelligence/OpenClaw-Medical-Skills.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~2.8kAutomated safety check: PassNo licence2 mo ago
24

Navigate protein structure hierarchy using Biopython Bio.PDB SMCRA model.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~2.3kAutomated safety check: PassNo licence2 mo ago
25

Read biological sequence files (FASTA, FASTQ, GenBank, EMBL, ABI, SFF) using Biopython Bio.SeqIO.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~2.6kAutomated safety check: PassNo licence2 mo ago
26

Perform multiple sequence alignment using MAFFT, MUSCLE5, ClustalOmega, or T-Coffee.

GPTomics/bioSkills1.2k2 repos~8.4kAutomated safety check: PassMIT1 mo ago
27

Parse and analyze multiple sequence alignments using Biopython.

majiayu000/claude-skill-registry6664 repos~5.5kAutomated safety check: PassMITtoday
28

Process many sequence files in batch (count, merge, split, convert, summarize) with memory-safe streaming and on-disk indexing using Biopython, pysam, or pyfastx.

GPTomics/bioSkills1.2k1 repo~3kAutomated safety check: PassMIT1 mo ago
29

Analyze codon usage and calculate CAI (Codon Adaptation Index), RSCU, and Nc with Biopython, and produce naive max-CAI codon-optimized sequences.

GPTomics/bioSkills1.2k1 repo~3.5kAutomated safety check: PassMIT1 mo ago
30

Read, write, and index compressed sequence files (gzip, bzip2, xz, BGZF) with Biopython and bgzip/samtools.

GPTomics/bioSkills1.2k1 repo~2.8kAutomated safety check: PassMIT1 mo ago
31

Work with FASTQ quality scores using Biopython - access Phred scores, filter and trim by quality, compute per-position profiles, and convert between Sanger/Phred+33, Solexa, and Illumina/Phred+64…

GPTomics/bioSkills1.2k1 repo~3.6kAutomated safety check: PassMIT1 mo ago
32

Filter and select sequences by criteria (length, ID, GC content, N content, motifs, patterns, description) using Biopython, streaming so large files never load into RAM.

GPTomics/bioSkills1.2k1 repo~3.3kAutomated safety check: PassMIT1 mo ago
33

Convert between sequence file formats (FASTA, FASTQ, GenBank, EMBL, Stockholm) and re-encode FASTQ quality offsets using Biopython Bio.SeqIO.

GPTomics/bioSkills1.2k1 repo~2.9kAutomated safety check: PassMIT1 mo ago
34

Find sequence motifs, degenerate IUPAC patterns, and transcription-factor binding sites in DNA/RNA using Biopython and regex, including position weight matrix (PWM/PSSM) scoring.

GPTomics/bioSkills1.2k1 repo~2.9kAutomated safety check: PassMIT1 mo ago
35

Handle paired-end FASTQ files (R1/R2) using Biopython while keeping mates synchronized.

GPTomics/bioSkills1.2k1 repo~3.3kAutomated safety check: PassMIT1 mo ago
36

Build model-corrected evolutionary distance matrices and distance trees (NJ, BIONJ, FastME, UPGMA) with Biopython Bio.Phylo plus R ape/phangorn/FastME.

GPTomics/bioSkills1.2k1 repo~4.9kAutomated safety check: PassMIT1 mo ago
37

Read, write, and convert phylogenetic tree files with Biopython Bio.Phylo, and choose an annotation-preserving parser (treeio, DendroPy) when metadata matters.

GPTomics/bioSkills1.2k1 repo~3.7kAutomated safety check: PassMIT1 mo ago
38

Edit phylogenetic tree structure with Biopython Bio.Phylo, and treat rooting as a separate statistical inference rather than a display choice.

GPTomics/bioSkills1.2k1 repo~5kAutomated safety check: PassMIT1 mo ago
39

Read biological sequence files (FASTA, FASTQ, GenBank, EMBL, ABI, SFF) with Biopython Bio.SeqIO, choosing between streaming, in-memory, and on-disk-indexed access.

GPTomics/bioSkills1.2k1 repo~3.5kAutomated safety check: PassMIT1 mo ago
40

Select restriction enzymes for cloning or diagnostics using Biopython Bio.Restriction.

GPTomics/bioSkills1.2k1 repo~3.4kAutomated safety check: PassMIT1 mo ago
41

Predict restriction digest fragment sizes and gel patterns using Biopython Bio.Restriction.

GPTomics/bioSkills1.2k1 repo~2.6kAutomated safety check: PassMIT1 mo ago
42

Design and validate Type IIS scarless DNA assembly (Golden Gate, MoClo) using Biopython Bio.Restriction.

GPTomics/bioSkills1.2k1 repo~2.9kAutomated safety check: PassMIT1 mo ago
43

Build restriction maps showing enzyme cut positions and inter-site distances along DNA using Biopython Bio.Restriction.

GPTomics/bioSkills1.2k1 repo~2.3kAutomated safety check: PassMIT1 mo ago
44

Find restriction enzyme cut sites in DNA sequences using Biopython Bio.Restriction.

GPTomics/bioSkills1.2k1 repo~2.5kAutomated safety check: PassMIT1 mo ago
45

Generate reverse complements and complements of DNA/RNA sequences using Biopython, including IUPAC ambiguity codes, gapped alignments, and minus-strand features.

GPTomics/bioSkills1.2k1 repo~2.8kAutomated safety check: PassMIT1 mo ago
46

Create and manipulate Seq, MutableSeq, and SeqRecord objects using Biopython.

GPTomics/bioSkills1.2k1 repo~2.5kAutomated safety check: PassMIT1 mo ago
47

Calculate nucleotide and protein sequence properties (GC content, GC skew, molecular weight, melting temperature, isoelectric point, instability, hydropathy) with Biopython.

GPTomics/bioSkills1.2k1 repo~4kAutomated safety check: PassMIT1 mo ago
48

Slice, extract, and concatenate biological sequences and annotated records using Biopython.

GPTomics/bioSkills1.2k1 repo~2.7kAutomated safety check: PassMIT1 mo ago

Questions, answered from the data.

What is the best Biopython skill?

Bio Alignment Io from GPTomics/bioSkills ranks first of the 71 Biopython skills listed here, with the highest score: its repository has 1.2k GitHub stars, 3 other GitHub owners carry a copy, its SKILL.md loads about 4.9k tokens and it passes the automated safety check with no findings. Next come Biopython Bioinformatics and Bio Write Sequences.

Is there an official Biopython skill?

None yet. All 71 Biopython skills listed here come from community repositories; a skill counts as official when the product's own GitHub organization publishes it.

How are these skills ranked?

By Skill Navigator score, which combines the GitHub stars of the skill's repository (shared across that repo's skills and discounted for large collections), how many other GitHub owners carry a copy of the skill, and automated SKILL.md quality checks, minus penalties for safety-check warnings and for each further skill from the same repository. Skills that fail the safety check are not listed.