By wu-yc

Retrieves chemical compound information from PubChem and ChEMBL with disambiguation, cross-referencing, and quality assessment.

wu-yc/LabClaw

Search and retrieve clinical practice guidelines across 12+ authoritative sources including NICE, WHO, ADA, AHA/ACC, NCCN, SIGN, CPIC, CMA, CTFPHC, GIN, MAGICapp, PubMed, EuropePMC, TRIP, and…

wu-yc/LabClaw

Generate comprehensive disease research reports using 100+ ToolUniverse tools.

wu-yc/LabClaw

Identify drug repurposing candidates using ToolUniverse for target-based, compound-based, and disease-driven strategies.

wu-yc/LabClaw

Retrieves gene expression and omics datasets from ArrayExpress and BioStudies with gene disambiguation, experiment quality assessment, and structured reports.

wu-yc/LabClaw

Perform comprehensive gene enrichment and pathway analysis using gseapy (ORA and GSEA), PANTHER, STRING, Reactome, and 40+ ToolUniverse tools.

wu-yc/LabClaw

Transform GWAS signals into actionable drug targets and repurposing opportunities.

wu-yc/LabClaw

Identify and prioritize causal variants at GWAS loci using statistical fine-mapping and locus-to-gene predictions.

wu-yc/LabClaw

Interpret genetic variants (SNPs) from GWAS studies by aggregating evidence from multiple databases (GWAS Catalog, Open Targets Genetics, ClinVar).

wu-yc/LabClaw

Compare GWAS studies, perform meta-analyses, and assess replication across cohorts.

wu-yc/LabClaw

Discover genes associated with diseases and traits using GWAS data from the GWAS Catalog (500,000+ associations) and Open Targets Genetics (L2G predictions).

wu-yc/LabClaw

Production-ready microscopy image analysis and quantitative imaging data skill for colony morphometry, cell counting, fluorescence quantification, and statistical analysis of imaging-derived…

wu-yc/LabClaw

Comprehensive immune repertoire analysis for T-cell and B-cell receptor sequencing data.

wu-yc/LabClaw

Analyze spatial transcriptomics data to map gene expression in tissue architecture.

wu-yc/LabClaw

Production-ready phylogenetics and sequence analysis skill for alignment processing, tree analysis, and evolutionary metrics.

wu-yc/LabClaw

Build and interpret polygenic risk scores (PRS) for complex diseases using GWAS summary statistics.

wu-yc/LabClaw

Retrieves protein structure data from RCSB PDB, PDBe, and AlphaFold with protein disambiguation, quality assessment, and comprehensive structural profiles.

wu-yc/LabClaw

Design novel protein therapeutics (binders, enzymes, scaffolds) using AI-guided de novo design.

wu-yc/LabClaw

Production-ready RNA-seq differential expression analysis using PyDESeq2.

wu-yc/LabClaw

Retrieves biological sequences (DNA, RNA, protein) from NCBI and ENA with gene disambiguation, accession type handling, and comprehensive sequence profiles.

wu-yc/LabClaw

Perform statistical modeling and regression analysis on biomedical datasets.

wu-yc/LabClaw

Comprehensive systems biology and pathway analysis using multiple pathway databases (Reactome, KEGG, WikiPathways, Pathway Commons, BioModels).

wu-yc/LabClaw

Detect and analyze adverse drug event signals using FDA FAERS data, drug labels, disproportionality analysis (PRR, ROR, IC), and biomedical evidence.

wu-yc/LabClaw

Comprehensive antibody engineering and optimization for therapeutic development.

wu-yc/LabClaw

Discover novel small molecule binders for protein targets using structure-based and ligand-based approaches.

wu-yc/LabClaw

Provide comprehensive clinical interpretation of somatic mutations in cancer.

wu-yc/LabClaw

Comprehensive chemical safety and toxicology assessment integrating ADMET-AI predictions, CTD toxicogenomics, FDA label safety data, DrugBank safety profiles, and STITCH chemical-protein interactions.

wu-yc/LabClaw

Strategic clinical trial design feasibility assessment using ToolUniverse.

wu-yc/LabClaw

AI-driven patient-to-trial matching for precision medicine and oncology.

wu-yc/LabClaw

Comprehensive CRISPR screen analysis for functional genomics.

wu-yc/LabClaw

Comprehensive computational validation of drug targets for early-stage drug discovery.

wu-yc/LabClaw

Production-ready genomics and epigenomics data processing for BixBench questions.

wu-yc/LabClaw

Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration.

wu-yc/LabClaw

Rapid pathogen characterization and drug repurposing analysis for infectious disease outbreaks.

wu-yc/LabClaw

Conduct comprehensive literature research with target disambiguation, evidence grading, and structured theme extraction.

wu-yc/LabClaw

Analyze metabolomics data including metabolite identification, quantification, pathway analysis, and metabolic flux.

wu-yc/LabClaw

Integrate and analyze multiple omics datasets (transcriptomics, proteomics, epigenomics, genomics, metabolomics) for systems biology and precision medicine.

wu-yc/LabClaw

Comprehensive multi-omics disease characterization integrating genomics, transcriptomics, proteomics, pathway, and therapeutic layers for systems-level understanding.

wu-yc/LabClaw

Construct and analyze compound-target-disease networks for drug repurposing, polypharmacology discovery, and systems pharmacology.

wu-yc/LabClaw

Analyze drug safety signals from FDA adverse event reports, label warnings, and pharmacogenomic data.

wu-yc/LabClaw

Comprehensive patient stratification for precision medicine by integrating genomic, clinical, and therapeutic data.

wu-yc/LabClaw

Provide actionable treatment recommendations for cancer patients based on molecular profile.

wu-yc/LabClaw

Analyze mass spectrometry proteomics data including protein quantification, differential expression, post-translational modifications (PTMs), and protein-protein interactions.

wu-yc/LabClaw

Provide differential diagnosis for patients with suspected rare diseases based on phenotype and genetic data.

wu-yc/LabClaw

Computational analysis framework for spatial multi-omics data integration.

wu-yc/LabClaw

Comprehensive structural variant (SV) analysis skill for clinical genomics.

wu-yc/LabClaw

Gather comprehensive biological target intelligence from 9 parallel research paths covering protein info, structure, interactions, pathways, expression, variants, drug interactions, and literature.

wu-yc/LabClaw

Systematic clinical variant interpretation from raw variant calls to ACMG-classified recommendations with structural impact analysis.

wu-yc/LabClaw