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Agent skill

Tooluniverse Clinical Trial Matching

by wu-yc in wu-yc/LabClaw

AI-driven patient-to-trial matching for precision medicine and oncology.

No licenceAuto-check passedResearch & Science

Install Tooluniverse Clinical Trial Matching

skills CLI
$ npx skills add wu-yc/LabClaw --skill tooluniverse-clinical-trial-matching -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install wu-yc/LabClaw tooluniverse-clinical-trial-matching --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/wu-yc/LabClaw.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/med/tooluniverse-clinical-trial-matching .claude/skills/tooluniverse-clinical-trial-matching && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
tooluniverse-clinical-trial-matching
GitHub stars
1.1k
Used in
2 other repos
Token cost
~13k tokens
SKILL.md length
2,310 words
Files
1
Skills in repo
68
Repo updated
First seen
Licence
None found

At a glance

AI-driven patient-to-trial matching for precision medicine and oncology.

  • Works in 11 steps: Tool Parameter Reference (CRITICAL) → Patient Profile Standardization → Broad Trial Discovery → …
  • Molecular tumor boards
  • SKILL.md covers When to Use, Input Parsing, Phase 0: Tool Parameter… and Workflow Overview, plus 3 more sections
  • Reaches clinicaltrials.gov

What it does

Tooluniverse Clinical Trial Matching is an agent skill from wu-yc/LabClaw. AI-driven patient-to-trial matching for precision medicine and oncology. Given a patient profile (disease, molecular alterations, stage, prior treatments), discovers and ranks clinical trials from ClinicalTrials.gov using multi-dimensional matching across molecular eligibility, clinical criteria, drug-biomarker alignment, evidence strength, and geographic feasibility. Produces a quantitative Trial Match Score (0-100) per trial with tiered recommendations and a comprehensive markdown report. Use when oncologists…

Its SKILL.md is about 13k tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.

It sits in Research & Science, covering Clinical and healthcare research. The repository describes itself as: LabClaw – Operating Layer for LabOS (Stanford-Princeton AI Co-Scientists).

When your agent uses it

  • Molecular tumor boards
  • Patients ask about clinical trial options for specific cancer types
  • Biomarker profiles
  • Post-progression scenarios

Example prompts

  • “/tooluniverse-clinical-trial-matching”

Workflow steps

11 steps, taken from the step headings in SKILL.md.

  1. Tool Parameter Reference (CRITICAL)
  2. Patient Profile Standardization
  3. Broad Trial Discovery
  4. Trial Characterization
  5. Molecular Eligibility Matching
  6. Drug-Biomarker Alignment
  7. Evidence Assessment
  8. Geographic & Feasibility Analysis
  9. Alternative Options
  10. Trial Match Scoring System
  11. Report Synthesis

What it can do on your machine

Read from SKILL.md and the folder at commit df37802. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md (its code samples are python and markdown).

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    Hosts in commands or code, which the agent is likely to contact:

    • clinicaltrials.gov

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Tooluniverse Clinical Trial Matching loads about 13k tokens when it runs. Until then it costs about 175 tokens; SKILL.md has 2,310 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~175
When it runs · the whole SKILL.md, loaded when a task matches
~13k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 2,310 words (~12,586 tokens).

“Transform patient molecular profiles and clinical characteristics into prioritized clinical trial recommendations. Searches ClinicalTrials.gov and cross-references with molecular databases (CIViC, OpenTargets, ChEMBL, FDA) to produce evidence-graded, scored trial matches.”

— opening of SKILL.md by wu-yc
name
tooluniverse-clinical-trial-matching

Read the full SKILL.md on GitHub

Files

Just SKILL.md in skills/med/tooluniverse-clinical-trial-matching of wu-yc/LabClaw.

Open the folder on GitHubat commit df37802

Used in 2 other repositories

We found 2 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 2 other GitHub owners. This page covers the copy in wu-yc/LabClaw, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Tooluniverse Clinical Trial Matching next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Tooluniverse Clinical Trial Matching compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Tooluniverse Clinical Trial Matching this skillwu-yc/LabClaw1.1k2 repos~13kAutomated safety check: PassNone
Clinical Trials Databasegoogle-deepmind/science-skills3.2k2 repos~3.2kAutomated safety check: PassApache-2.0
CHARLS Paper Reproduction Guidexjtulyc/MedgeClaw6171 repos~1.8kAutomated safety check: PassNone
Biomedical Analysis Dispatchxjtulyc/MedgeClaw6171 repos~2kAutomated safety check: PassNone
Research Paperluwill/research-skills862—~1.9kAutomated safety check: PassNone
Research Proposalluwill/research-skills862—~4.5kAutomated safety check: NotesNone

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All 68 skills in this repo

  • Tooluniverse Chemical Compound Retrieval

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  • Tooluniverse Clinical Guidelines

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  • Tooluniverse Disease Research

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    Generate comprehensive disease research reports using 100+ ToolUniverse tools.

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  • Tooluniverse Drug Repurposing

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    Identify drug repurposing candidates using ToolUniverse for target-based, compound-based, and disease-driven strategies.

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  • Tooluniverse Expression Data Retrieval

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    Retrieves gene expression and omics datasets from ArrayExpress and BioStudies with gene disambiguation, experiment quality assessment, and structured reports.

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  • Tooluniverse Gene Enrichment

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    Perform comprehensive gene enrichment and pathway analysis using gseapy (ORA and GSEA), PANTHER, STRING, Reactome, and 40+ ToolUniverse tools.

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Categories

Questions about Tooluniverse Clinical Trial Matching

What does Tooluniverse Clinical Trial Matching do?

AI-driven patient-to-trial matching for precision medicine and oncology. Tooluniverse Clinical Trial Matching is an agent skill from wu-yc/LabClaw. AI-driven patient-to-trial matching for precision medicine and oncology.

When should I use Tooluniverse Clinical Trial Matching?

Tooluniverse Clinical Trial Matching fits situations like: molecular tumor boards; patients ask about clinical trial options for specific cancer types; biomarker profiles; post-progression scenarios.

How do I install Tooluniverse Clinical Trial Matching in Claude Code?

Run `npx skills add wu-yc/LabClaw --skill tooluniverse-clinical-trial-matching -a claude-code`. Or copy the skill folder (skills/med/tooluniverse-clinical-trial-matching in wu-yc/LabClaw) into .claude/skills/tooluniverse-clinical-trial-matching in your project. Claude Code loads it when a task matches its description.

How do I install Tooluniverse Clinical Trial Matching in Codex?

Run `npx skills add wu-yc/LabClaw --skill tooluniverse-clinical-trial-matching -a codex`. Or copy the skill folder (skills/med/tooluniverse-clinical-trial-matching in wu-yc/LabClaw) into .agents/skills/tooluniverse-clinical-trial-matching in your project. Codex loads it when a task matches its description.

Can I use Tooluniverse Clinical Trial Matching in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add wu-yc/LabClaw --skill tooluniverse-clinical-trial-matching -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/tooluniverse-clinical-trial-matching, .gemini/skills/tooluniverse-clinical-trial-matching, .github/skills/tooluniverse-clinical-trial-matching and .opencode/skills/tooluniverse-clinical-trial-matching in your project.

What does Tooluniverse Clinical Trial Matching need to run?

SKILL.md names no scripts, command-line tools or credentials: Tooluniverse Clinical Trial Matching is instructions for the agent only.

Does Tooluniverse Clinical Trial Matching access the network?

SKILL.md names 1 domain. In commands or code: clinicaltrials.gov; the agent is likely to contact it when it follows the instructions. This is read from the text; nothing was executed.

Is Tooluniverse Clinical Trial Matching safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Tooluniverse Clinical Trial Matching use?

No licence was found for Tooluniverse Clinical Trial Matching or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Tooluniverse Clinical Trial Matching use?

About 13k tokens (SKILL.md is roughly 50k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Tooluniverse Clinical Trial Matching?

Skills that share tags, products or a category with Tooluniverse Clinical Trial Matching: Clinical Trials Database (google-deepmind/science-skills, 3.2k stars), CHARLS Paper Reproduction Guide (xjtulyc/MedgeClaw, 617 stars), Biomedical Analysis Dispatch (xjtulyc/MedgeClaw, 617 stars) and Research Paper (luwill/research-skills, 862 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Tooluniverse Clinical Trial Matching?

wu-yc (a GitHub user) maintains it in wu-yc/LabClaw, which has 1,055 GitHub stars. The repository holds 68 skills in this directory. The repository was last updated on March 19, 2026.

Source: wu-yc/LabClaw on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.