Agent skill

Tooluniverse Clinical Trial Design

by wu-yc in wu-yc/LabClaw

Strategic clinical trial design feasibility assessment using ToolUniverse.

No licenceAuto-check passedResearch & Science

Install Tooluniverse Clinical Trial Design

skills CLI
$ npx skills add wu-yc/LabClaw --skill tooluniverse-clinical-trial-design -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install wu-yc/LabClaw tooluniverse-clinical-trial-design --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/wu-yc/LabClaw.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/med/tooluniverse-clinical-trial-design .claude/skills/tooluniverse-clinical-trial-design && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
tooluniverse-clinical-trial-design
GitHub stars
1.1k
Used in
2 other repos
Token cost
~11k tokens
SKILL.md length
1,304 words
Files
1
Skills in repo
68
Repo updated
First seen
Licence
None found

At a glance

Strategic clinical trial design feasibility assessment using ToolUniverse.

  • Works in 12 steps: Report-First Approach (MANDATORY) → Evidence Grading System → Feasibility Score (0-100) → …
  • Planning Phase 1/2 trials
  • SKILL.md covers Core Principles, When to Use This Skill, Quick Start and Core Strategy: 6 Research Paths, plus 4 more sections
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Tooluniverse Clinical Trial Design is an agent skill from wu-yc/LabClaw. Strategic clinical trial design feasibility assessment using ToolUniverse. Evaluates patient population sizing, biomarker prevalence, endpoint selection, comparator analysis, safety monitoring, and regulatory pathways. Creates comprehensive feasibility reports with evidence grading, enrollment projections, and trial design recommendations. Use when planning Phase 1/2 trials, assessing trial feasibility, or designing biomarker-driven studies.

Its SKILL.md is about 11k tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.

It sits in Research & Science, covering Experimental design. The repository describes itself as: LabClaw – Operating Layer for LabOS (Stanford-Princeton AI Co-Scientists).

When your agent uses it

  • Planning Phase 1/2 trials
  • Assessing trial feasibility
  • Designing biomarker-driven studies

Example prompts

  • “/tooluniverse-clinical-trial-design”

Requirements

  • Python 3

Workflow steps

12 steps, taken from the step headings in SKILL.md.

  1. Report-First Approach (MANDATORY)
  2. Evidence Grading System
  3. Feasibility Score (0-100)
  4. Executive Summary
  5. Disease Background
  6. Patient Population Analysis
  7. Biomarker Strategy
  8. Endpoint Selection & Justification
  9. Comparator Analysis
  10. Safety Endpoints & Monitoring Plan
  11. Enrollment & Site Strategy
  12. Regulatory Pathway

What it can do on your machine

Read from SKILL.md and the folder at commit df37802. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md (its code samples are markdown and python).

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    Links to these hosts (documentation or services it may open):

    • zitniklab.hms.harvard.edu
    • fda.gov
    • clinicaltrials.gov
    • join.slack.com

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Tooluniverse Clinical Trial Design loads about 11k tokens when it runs. Until then it costs about 120 tokens; SKILL.md has 1,304 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~120
When it runs · the whole SKILL.md, loaded when a task matches
~11k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 1,304 words (~10,735 tokens).

“Systematically assess clinical trial feasibility by analyzing 6 research dimensions. Produces comprehensive feasibility reports with quantitative enrollment projections, endpoint recommendations, and regulatory pathway analysis.”

— opening of SKILL.md by wu-yc
name
tooluniverse-clinical-trial-design

Read the full SKILL.md on GitHub

Files

Just SKILL.md in skills/med/tooluniverse-clinical-trial-design of wu-yc/LabClaw.

Open the folder on GitHubat commit df37802

Used in 2 other repositories

We found 2 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 2 other GitHub owners. This page covers the copy in wu-yc/LabClaw, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Tooluniverse Clinical Trial Design next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Tooluniverse Clinical Trial Design compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Tooluniverse Clinical Trial Design this skillwu-yc/LabClaw1.1k2 repos~11kAutomated safety check: PassNone
Scientific Critical Thinkingweapp-tailwindcss/weapp-tailwindcss1.9k22 repos~5.9kAutomated safety check: NotesMIT
Benchmark Paper TemplateHKUSTDial/Supervisor-Skills8.8k—~2.8kAutomated safety check: PassCC-BY-4.0
Claim-Driven Experiment PlannerzjYao36/Auto-Research-Refine1286 repos~2.3kAutomated safety check: NotesNone
Research Refine PipelinezjYao36/Auto-Research-Refine1285 repos~1.4kAutomated safety check: NotesNone
Metabolic Study Planneraiming-lab/AutoResearchClaw15k—~1.9kAutomated safety check: PassMIT

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Questions about Tooluniverse Clinical Trial Design

What does Tooluniverse Clinical Trial Design do?

Strategic clinical trial design feasibility assessment using ToolUniverse. Tooluniverse Clinical Trial Design is an agent skill from wu-yc/LabClaw. Strategic clinical trial design feasibility assessment using ToolUniverse.

When should I use Tooluniverse Clinical Trial Design?

Tooluniverse Clinical Trial Design fits situations like: planning Phase 1/2 trials; assessing trial feasibility; designing biomarker-driven studies.

How do I install Tooluniverse Clinical Trial Design in Claude Code?

Run `npx skills add wu-yc/LabClaw --skill tooluniverse-clinical-trial-design -a claude-code`. Or copy the skill folder (skills/med/tooluniverse-clinical-trial-design in wu-yc/LabClaw) into .claude/skills/tooluniverse-clinical-trial-design in your project. Claude Code loads it when a task matches its description.

How do I install Tooluniverse Clinical Trial Design in Codex?

Run `npx skills add wu-yc/LabClaw --skill tooluniverse-clinical-trial-design -a codex`. Or copy the skill folder (skills/med/tooluniverse-clinical-trial-design in wu-yc/LabClaw) into .agents/skills/tooluniverse-clinical-trial-design in your project. Codex loads it when a task matches its description.

Can I use Tooluniverse Clinical Trial Design in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add wu-yc/LabClaw --skill tooluniverse-clinical-trial-design -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/tooluniverse-clinical-trial-design, .gemini/skills/tooluniverse-clinical-trial-design, .github/skills/tooluniverse-clinical-trial-design and .opencode/skills/tooluniverse-clinical-trial-design in your project.

What does Tooluniverse Clinical Trial Design need to run?

SKILL.md names no scripts, command-line tools or credentials: Tooluniverse Clinical Trial Design is instructions for the agent only. Our summary lists: Python 3.

Does Tooluniverse Clinical Trial Design access the network?

SKILL.md names 4 domains. As links in the text: zitniklab.hms.harvard.edu, fda.gov, clinicaltrials.gov and join.slack.com. This is read from the text; nothing was executed.

Is Tooluniverse Clinical Trial Design safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Tooluniverse Clinical Trial Design use?

No licence was found for Tooluniverse Clinical Trial Design or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Tooluniverse Clinical Trial Design use?

About 11k tokens (SKILL.md is roughly 43k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Tooluniverse Clinical Trial Design?

Skills that share tags, products or a category with Tooluniverse Clinical Trial Design: Scientific Critical Thinking (weapp-tailwindcss/weapp-tailwindcss, 1.9k stars), Benchmark Paper Template (HKUSTDial/Supervisor-Skills, 8.8k stars), Claim-Driven Experiment Planner (zjYao36/Auto-Research-Refine, 128 stars) and Research Refine Pipeline (zjYao36/Auto-Research-Refine, 128 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Tooluniverse Clinical Trial Design?

wu-yc (a GitHub user) maintains it in wu-yc/LabClaw, which has 1,055 GitHub stars. The repository holds 68 skills in this directory. The repository was last updated on March 19, 2026.

Source: wu-yc/LabClaw on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.