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Agent skill

Tooluniverse Drug Target Validation

by wu-yc in wu-yc/LabClaw

Comprehensive computational validation of drug targets for early-stage drug discovery.

No licenceAuto-check passedProduct & Project Management

Install Tooluniverse Drug Target Validation

skills CLI
$ npx skills add wu-yc/LabClaw --skill tooluniverse-drug-target-validation -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install wu-yc/LabClaw tooluniverse-drug-target-validation --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/wu-yc/LabClaw.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/pharma/tooluniverse-drug-target-validation .claude/skills/tooluniverse-drug-target-validation && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
tooluniverse-drug-target-validation
GitHub stars
1.1k
Used in
2 other repos
Token cost
~9.9k tokens
SKILL.md length
1,314 words
Files
1
Skills in repo
68
Repo updated
First seen
Licence
None found

At a glance

Comprehensive computational validation of drug targets for early-stage drug discovery.

  • Works in 11 steps: Target Disambiguation & ID Resolution… → Disease Association Evidence (0-30 points) → Druggability Assessment (0-25 points) → …
  • Users ask about target validation
  • SKILL.md covers When to Use This Skill, Input Parameters, Target Validation Scoring System and Phase 0: Target Disambiguation…, plus 4 more sections
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Tooluniverse Drug Target Validation is an agent skill from wu-yc/LabClaw. Comprehensive computational validation of drug targets for early-stage drug discovery. Evaluates targets across 10 dimensions (disambiguation, disease association, druggability, chemical matter, clinical precedent, safety, pathway context, validation evidence, structural insights, validation roadmap) using 60+ ToolUniverse tools. Produces a quantitative Target Validation Score (0-100) with GO/NO-GO recommendation. Use when users ask about target validation, druggability assessment, target prioritization, or "is X…

Its SKILL.md is about 9.9k tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.

It sits in Product & Project Management, covering Feature launches and release readiness, Drug discovery and cheminformatics and Prioritization frameworks. The repository describes itself as: LabClaw – Operating Layer for LabOS (Stanford-Princeton AI Co-Scientists).

When your agent uses it

  • Users ask about target validation
  • Druggability assessment
  • Target prioritization
  • Is X a good drug target for Y?

Example prompts

  • “is X a good drug target for Y?”
  • “/tooluniverse-drug-target-validation”

Requirements

  • Python 3

Workflow steps

11 steps, taken from the step headings in SKILL.md.

  1. Target Disambiguation & ID Resolution (ALWAYS FIRST)
  2. Disease Association Evidence (0-30 points)
  3. Druggability Assessment (0-25 points)
  4. Known Modulators & Chemical Matter (Feeds into Phase 2 scoring)
  5. Clinical Precedent (0-15 points)
  6. Safety & Toxicity Considerations (0-20 points)
  7. Pathway Context & Network Analysis
  8. Validation Evidence (0-10 points)
  9. Structural Insights
  10. Literature Deep Dive
  11. Validation Roadmap (Synthesis)

What it can do on your machine

Read from SKILL.md and the folder at commit df37802. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md (its code samples are python and markdown).

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Tooluniverse Drug Target Validation loads about 9.9k tokens when it runs. Until then it costs about 145 tokens; SKILL.md has 1,314 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~145
When it runs · the whole SKILL.md, loaded when a task matches
~9.9k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 1,314 words (~9,941 tokens).

“Validate drug target hypotheses using multi-dimensional computational evidence before committing to wet-lab work. Produces a quantitative Target Validation Score (0-100) with priority tier classification and GO/NO-GO recommendation.”

— opening of SKILL.md by wu-yc
name
tooluniverse-drug-target-validation

Read the full SKILL.md on GitHub

Files

Just SKILL.md in skills/pharma/tooluniverse-drug-target-validation of wu-yc/LabClaw.

Open the folder on GitHubat commit df37802

Used in 2 other repositories

We found 2 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 2 other GitHub owners. This page covers the copy in wu-yc/LabClaw, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Tooluniverse Drug Target Validation next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Tooluniverse Drug Target Validation compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Tooluniverse Drug Target Validation this skillwu-yc/LabClaw1.1k2 repos~9.9kAutomated safety check: PassNone
Product Lensaffaan-m/ECC277k2 repos~841Automated safety check: PassMIT
Medchemaipoch/medical-research-skills1.9k—~1.3kAutomated safety check: PassMIT
Test Planningpetrkindlmann/qa-skills170—~4.2kAutomated safety check: PassMIT
Repo Genomeruvnet/metaharness696—~772Automated safety check: PassMIT
Open Targets PlatformQSong-github/DrugClaw1161 repos~601Automated safety check: PassNone

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More from wu-yc/LabClaw

All 68 skills in this repo

  • Tooluniverse Chemical Compound Retrieval

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    Retrieves chemical compound information from PubChem and ChEMBL with disambiguation, cross-referencing, and quality assessment.

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  • Tooluniverse Clinical Guidelines

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  • Tooluniverse Disease Research

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    Generate comprehensive disease research reports using 100+ ToolUniverse tools.

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  • Tooluniverse Drug Repurposing

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    Identify drug repurposing candidates using ToolUniverse for target-based, compound-based, and disease-driven strategies.

    1.1k GitHub starsUsed in 2 repos~4.4k tokens
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  • Tooluniverse Expression Data Retrieval

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    Retrieves gene expression and omics datasets from ArrayExpress and BioStudies with gene disambiguation, experiment quality assessment, and structured reports.

    1.1k GitHub starsUsed in 2 repos~2.6k tokens
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  • Tooluniverse Gene Enrichment

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    Perform comprehensive gene enrichment and pathway analysis using gseapy (ORA and GSEA), PANTHER, STRING, Reactome, and 40+ ToolUniverse tools.

    1.1k GitHub starsUsed in 2 repos~4k tokens
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Categories

Questions about Tooluniverse Drug Target Validation

What does Tooluniverse Drug Target Validation do?

Comprehensive computational validation of drug targets for early-stage drug discovery. Tooluniverse Drug Target Validation is an agent skill from wu-yc/LabClaw. Comprehensive computational validation of drug targets for early-stage drug discovery.

When should I use Tooluniverse Drug Target Validation?

Tooluniverse Drug Target Validation fits situations like: users ask about target validation; druggability assessment; target prioritization; is X a good drug target for Y?.

How do I install Tooluniverse Drug Target Validation in Claude Code?

Run `npx skills add wu-yc/LabClaw --skill tooluniverse-drug-target-validation -a claude-code`. Or copy the skill folder (skills/pharma/tooluniverse-drug-target-validation in wu-yc/LabClaw) into .claude/skills/tooluniverse-drug-target-validation in your project. Claude Code loads it when a task matches its description.

How do I install Tooluniverse Drug Target Validation in Codex?

Run `npx skills add wu-yc/LabClaw --skill tooluniverse-drug-target-validation -a codex`. Or copy the skill folder (skills/pharma/tooluniverse-drug-target-validation in wu-yc/LabClaw) into .agents/skills/tooluniverse-drug-target-validation in your project. Codex loads it when a task matches its description.

Can I use Tooluniverse Drug Target Validation in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add wu-yc/LabClaw --skill tooluniverse-drug-target-validation -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/tooluniverse-drug-target-validation, .gemini/skills/tooluniverse-drug-target-validation, .github/skills/tooluniverse-drug-target-validation and .opencode/skills/tooluniverse-drug-target-validation in your project.

What does Tooluniverse Drug Target Validation need to run?

SKILL.md names no scripts, command-line tools or credentials: Tooluniverse Drug Target Validation is instructions for the agent only. Our summary lists: Python 3.

Does Tooluniverse Drug Target Validation access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Tooluniverse Drug Target Validation safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Tooluniverse Drug Target Validation use?

No licence was found for Tooluniverse Drug Target Validation or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Tooluniverse Drug Target Validation use?

About 9.9k tokens (SKILL.md is roughly 40k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Tooluniverse Drug Target Validation?

Skills that share tags, products or a category with Tooluniverse Drug Target Validation: Product Lens (affaan-m/ECC, 277k stars), Medchem (aipoch/medical-research-skills, 1.9k stars), Test Planning (petrkindlmann/qa-skills, 170 stars) and Repo Genome (ruvnet/metaharness, 696 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Tooluniverse Drug Target Validation?

wu-yc (a GitHub user) maintains it in wu-yc/LabClaw, which has 1,055 GitHub stars. The repository holds 68 skills in this directory. The repository was last updated on March 19, 2026.

Source: wu-yc/LabClaw on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.