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Bioinformatics
Skills
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| # | Skill | Repository | Stars | Used in | Tokens | Auto-check | Licence | Updated |
|---|---|---|---|---|---|---|---|---|
| 1 | Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. | spacering-net/ | 3.8k | 15 repos | ~3.6k | Automated safety check: Pass | MIT | yesterday |
| 2 | A skill your agent uses when you want to look up, map, and search for short genetic variants (SNPs, indels) in NCBI's dbSNP database. | google-deepmind/ | 3.2k | 3 repos | ~3.4k | Automated safety check: Notes | Apache-2.0 | 23 days ago |
| 3 | Turns a broad metabolic modelling topic into a concrete, paper-shaped plan with organism, model, perturbations, metrics and figures before any FBA code is written. | aiming-lab/ | 15k | — | ~1.9k | Automated safety check: Pass | MIT | 1 mo ago |
| 4 | Estimates reaction fluxes inside cells from steady-state carbon-13 labeling data with a bundled mfapy-based solver, and reports which fluxes the data pin down. | K-Dense-AI/ | 48k | 1 repo | ~3.2k | Automated safety check: Pass | MIT | 3 days ago |
| 5 | Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API. | google-deepmind/ | 3.2k | 2 repos | ~3k | Automated safety check: Notes | Apache-2.0 | 23 days ago |
| 6 | Runs a metabolic flux analysis from model loading to phenotype prediction and figures by handing work to four sub-agents in sequence. | aiming-lab/ | 15k | — | ~923 | Automated safety check: Pass | MIT | 1 mo ago |
| 7 | A skill your agent uses when designing, reviewing, or implementing single-cell RNA-seq QC in Python or R with a human-in-the-loop, data-driven approach. | xuzhougeng/ | 1k | — | ~1.6k | Automated safety check: Pass | AGPL-3.0 | today |
| 8 | Generate a specialized domain-expert research agent modeled on PaperClaw architecture. | guhaohao0991/ | 250 | — | ~2k | Automated safety check: Pass | No licence | 7 mo ago |
| 9 | 9.Borzoi Predict genome-wide functional tracks (RNA-seq, CAGE, DNase, ChIP) from DNA sequence with Borzoi. | JimLiu/ | 227 | 4 repos | ~973 | Automated safety check: Pass | Apache-2.0 | 3 mo ago |
| 10 | Routes bioinformatics, drug discovery, clinical and multi-omics tasks from a chat interface to Claude Code sessions running K-Dense scientific skills, with a live dashboard per task. | xjtulyc/ | 617 | 1 repo | ~2k | Automated safety check: Pass | No licence | 7 mo ago |
| 11 | 11.Genomi A skill your agent uses for genetics, genome source, variant, gene, phenotype, disease, screen, pharmacogenomics, and Genomi install/setup maintenance questions. | exon-research/ | 484 | — | ~4k | Automated safety check: Pass | Apache-2.0 | 1 mo ago |
| 12 | A skill your agent uses when needing clinical significance, pathogenicity classifications (e.g., Pathogenic, Benign, VUS), clinical evidence rationales, or finding "hard positive" benchmark controls… | google-deepmind/ | 3.2k | 2 repos | ~3.9k | Automated safety check: Notes | Apache-2.0 | 23 days ago |
| 13 | Analyze single-cell data with core Scarf, the out-of-core Zarr DataStore library with immutable artifacts and pipeline runs. | NygenAnalytics/ | 126 | — | ~5.6k | Automated safety check: Pass | BSD-3-Clause | yesterday |
| 14 | 14.Tbtools A skill your agent uses when the user asks about TBtools, TBtools-II, TBtools RPC API, TBtools CLI, or bioinformatics operations available through TBtools such as sequence manipulation, BLAST… | xuzhougeng/ | 442 | — | ~2.3k | Automated safety check: Pass | MIT | 3 days ago |
| 15 | Routes agents to the right tangermeme reference for analyzing trained genomic deep learning models, from attributions and motif experiments to variant effects and design. | jmschrei/ | 311 | — | ~1.6k | Automated safety check: Pass | MIT | yesterday |
| 16 | 16.Parabricks Route NVIDIA Parabricks pbrun tools, assess GPU/runtime readiness, and provide version-aware command guidance for FASTQ/BAM processing, RNA-seq, variant calling, BAM QC, and GVCF workflows. | NVIDIA-BioNeMo/ | 478 | — | ~2.1k | Automated safety check: Pass | Apache-2.0 | yesterday |
| 17 | 17.Snpeff Run SnpEff, a variant annotation and effect prediction tool for genomic variants. | pcingola/ | 313 | — | ~823 | Automated safety check: Notes | Unknown | 7 mo ago |
| 18 | Builds or loads a genome-scale metabolic model in COBRApy, sets its growth medium and objective, and exports it as a validated JSON file for flux analysis. | aiming-lab/ | 15k | — | ~1.4k | Automated safety check: Pass | MIT | 1 mo ago |
| 19 | 19.Evo2 Score, embed, and generate DNA sequences with Evo 2, a long-context genomic foundation model. | JimLiu/ | 227 | 4 repos | ~1.3k | Automated safety check: Pass | Apache-2.0 | 3 mo ago |
| 20 | 20.Trackplot Generate sashimi-style genome visualization plots (coverage, line, heatmap, IGV read-by-read, HiC, circRNA, motif) from BAM/bigWig/depth/HiC inputs. | ygidtu/ | 109 | — | ~1.9k | Automated safety check: Pass | BSD-3-Clause | 12 days ago |
| 21 | 21.Ngless Auto-activate when the user mentions NGLess, ngless, NGS processing, metagenomics pipelines with NGLess, writing .ngl scripts, or is working in the ngless repository (Rust source at src/). | ngless-toolkit/ | 152 | — | ~7k | Automated safety check: Pass | Unknown | 7 days ago |
| 22 | A skill your agent uses when a researcher needs to query biomedical databases for biomarker discovery, build target profiles from UniProt/Open Targets/STRING, rank biomarker candidates by evidence… | aws-samples/ | 274 | — | ~1.1k | Automated safety check: Pass | MIT-0 | 7 days ago |
| 23 | 23.Jj Flow jujutsu (jj) command cheatsheet for this colocated jj+git Bioconductor repo. | seandavi/ | 118 | — | ~981 | Automated safety check: Pass | Unknown | 1 mo ago |
| 24 | 24.Flexynesis Run flexynesis, a deep-learning suite for multi-omics data integration and clinical outcome prediction (drug response, cancer subtyping, survival analysis). | BIMSBbioinfo/ | 110 | — | ~2.3k | Automated safety check: Pass | Unknown | 29 days ago |
| 25 | Read, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO. | GPTomics/ | 1.2k | 3 repos | ~4.9k | Automated safety check: Pass | MIT | 1 mo ago |
| 26 | Generate Amazon and cross-border ecommerce product images from a product business card. | binggandata/ | 603 | — | ~2.4k | Automated safety check: Pass | MIT | 1 mo ago |
| 27 | Installs the bioSkills collection of 425 bioinformatics skills in one step, or only chosen categories, so sequencing, RNA-seq, single-cell and variant tasks get specialized help. | GPTomics/ | 1.2k | 1 repo | ~789 | Automated safety check: Pass | MIT | 1 mo ago |
| 28 | Query the Genome Aggregation Database (gnomAD). An agent skill from google-deepmind/science-skills. | google-deepmind/ | 3.2k | 2 repos | ~775 | Automated safety check: Pass | Apache-2.0 | 23 days ago |
| 29 | A skill your agent uses when interpreting genomic variants from VCF files, performing clinical variant classification using ClinVar/VEP annotations, analyzing allele frequencies against population… | aws-samples/ | 274 | — | ~1.5k | Automated safety check: Pass | MIT-0 | 7 days ago |
| 30 | Fine-tune or transfer-learn AlphaGenome-PyTorch on custom genomic data — pick a mode (linear probe, LoRA, Locon, full), train on BigWig tracks with agt finetune, use adapters, delta checkpoints… | genomicsxai/ | 162 | — | ~1k | Automated safety check: Pass | Apache-2.0 | 23 days ago |
| 31 | Workflow for fixing or changing RNAlysis code that talks to an EXTERNAL WEB SERVICE — UniProt, Ensembl, PANTHER, PhylomeDB, OrthoInspector, KEGG, or GO. | GuyTeichman/ | 140 | — | ~1.8k | Automated safety check: Pass | MIT | 10 days ago |
| 32 | Quick reference for Biopython work: sequence operations, SeqIO file parsing, BLAST searches, Entrez queries, phylogenetic trees and PDB structure analysis. | aiming-lab/ | 15k | — | ~810 | Automated safety check: Pass | MIT | 1 mo ago |
| 33 | Queries the UniProt REST API directly to search proteins, fetch FASTA sequences, map IDs between databases and read Swiss-Prot and TrEMBL entries. | davila7/ | 32k | 15 repos | ~1.7k | Automated safety check: Pass | MIT | today |
| 34 | Build and analyze phylogenetic trees using MAFFT (multiple alignment), IQ-TREE 2 (maximum likelihood), and FastTree (fast NJ/ML). | LeonChaoX/ | 938 | 2 repos | ~3.5k | Automated safety check: Pass | MIT | 2 mo ago |
| 35 | Write biological sequences to files (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO. | GPTomics/ | 1.2k | 3 repos | ~2.1k | Automated safety check: Pass | MIT | 1 mo ago |
| 36 | Write, edit, or review gbdraw pull request titles and maintainer-facing descriptions. | satoshikawato/ | 154 | — | ~539 | Automated safety check: Pass | MIT | today |
| 37 | A skill your agent uses when a developer wants to build a new healthcare or life sciences agent, structure tools and system prompts for an HCLS workflow, or create a Strands agent with… | aws-samples/ | 274 | — | ~885 | Automated safety check: Pass | MIT-0 | 7 days ago |
| 38 | Walks through single-cell RNA-seq analysis with Scanpy: loading .h5ad and 10X data, QC, normalization, PCA and UMAP, Leiden clustering, marker genes and cell type annotation. | davila7/ | 32k | 16 repos | ~2.8k | Automated safety check: Pass | MIT | today |
| 39 | 39.Arboreto Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). | davila7/ | 32k | 12 repos | ~1.7k | Automated safety check: Pass | MIT | today |
| 40 | Run AlphaGenome-PyTorch to get genomic track predictions — via the agt predict CLI (single locus, BED regions, whole chromosomes, raw FASTA sequences, or per-gene count tables/AnnData), variant… | genomicsxai/ | 162 | — | ~868 | Automated safety check: Pass | Apache-2.0 | 23 days ago |
| 41 | Capture and attach RNAlysis GUI screenshots to a PR whenever a change makes a VISIBLE difference to a GUI dialog. | GuyTeichman/ | 140 | — | ~2k | Automated safety check: Pass | MIT | 10 days ago |
| 42 | 42.Scgpt Embed and annotate single-cell expression data with scGPT, a foundation model for single-cell biology. | JimLiu/ | 227 | 4 repos | ~1.3k | Automated safety check: Pass | Apache-2.0 | 3 mo ago |
| 43 | 43.Genomilab Run or continue patient-authorized, genome-informed GenomiLab investigations in the current Claude, Codex, or other MCP agent task. | exon-research/ | 484 | — | ~4.2k | Automated safety check: Pass | Apache-2.0 | 1 mo ago |
| 44 | Implements a new bioinformatics tool wrapper in proto-tools using a parallelized agent pipeline. | evo-design/ | 135 | — | ~15k | Automated safety check: Notes | MIT | yesterday |
| 45 | 45.Bulkrna De Load when comparing gene expression between two conditions in bulk RNA-seq count data. | TianGzlab/ | 161 | 1 repo | ~867 | Automated safety check: Pass | Apache-2.0 | yesterday |
| 46 | End-to-end 10x Visium spatial transcriptomics analysis workflow with staged execution and human review gates. | QING1105/ | 101 | — | ~1.4k | Automated safety check: Pass | MIT | 1 mo ago |
| 47 | Guides use of deepTools on sequencing data: BAM to bigWig conversion, QC, sample correlation, and heatmaps or profiles around TSS and peaks for ChIP-seq, RNA-seq and ATAC-seq. | davila7/ | 32k | 13 repos | ~4.5k | Automated safety check: Pass | MIT | today |
| 48 | Reproducible Scanpy workflow for human or mouse 10x scRNA-seq and snRNA-seq count matrices: single-sample descriptive QC, clustering and annotation, or comparative donor-aware pseudobulk DE and Milo… | PKU-YuanGroup/ | 617 | — | ~1.3k | Automated safety check: Pass | MIT | 3 days ago |