Library

Scanpy agent skills for Claude Code, Codex and other agents.

Scalable Python toolkit for analysing single-cell gene expression data.
skills
47
Type
Library
Website
scanpy.readthedocs.io
Official GitHub
scverse

Scanpy skills, ranked

Ranked by score. Sort bymost stars,trending,newest,recently updated

Scanpy skills, ranked
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1

Walks through single-cell RNA-seq analysis with Scanpy: loading .h5ad and 10X data, QC, normalization, PCA and UMAP, Leiden clustering, marker genes and cell type annotation.

davila7/claude-code-templates32k16 repos~2.8kAutomated safety check: PassMITtoday
2

Reproducible Scanpy workflow for human or mouse 10x scRNA-seq and snRNA-seq count matrices: single-sample descriptive QC, clustering and annotation, or comparative donor-aware pseudobulk DE and Milo…

PKU-YuanGroup/OpenAI4S608—~1.3kAutomated safety check: PassMIT2 days ago
3

This skill should be used when working with annotated data matrices in Python, particularly for single-cell genomics analysis, managing experimental measurements with metadata, or handling…

davila7/claude-code-templates32k12 repos~2.5kAutomated safety check: PassMITtoday
4

Query CZ CELLxGENE Census (61M+ cells). An agent skill from davila7/claude-code-templates.

davila7/claude-code-templates32k11 repos~3.8kAutomated safety check: PassMITtoday
5

Prepares bulk RNA-seq FASTQ, Salmon, STAR or featureCounts output for gene-level differential expression.

K-Dense-AI/scientific-agent-skills48k1 repo~4.2kAutomated safety check: PassMIT2 days ago
6

Performs pathway and gene-set enrichment analysis on gene lists or ranked gene data and interprets the results.

K-Dense-AI/scientific-agent-skills48k1 repo~4.2kAutomated safety check: PassMIT2 days ago
7

Performs RNA velocity analysis with scVelo from spliced and unspliced single-cell RNA counts.

K-Dense-AI/scientific-agent-skills48k1 repo~3.1kAutomated safety check: PassBSD-3-Clause2 days ago
8

Performs Scanpy single-cell RNA-seq QC, normalization, HVG selection, PCA/UMAP/t-SNE, clustering, exploratory marker ranking, pseudobulk preparation, visualization, and Seurat or…

K-Dense-AI/scientific-agent-skills48k1 repo~5.1kAutomated safety check: PassBSD-3-Clause2 days ago
9

Queries the CZ CELLxGENE Census programmatically for versioned public single-cell and spatial transcriptomics data.

K-Dense-AI/scientific-agent-skills48k1 repo~3.4kAutomated safety check: NotesMIT2 days ago
10

Fits probabilistic models for single-cell omics, including scVI batch integration, scANVI annotation, totalVI CITE-seq, MultiVI RNA/ATAC integration, and posterior differential expression.

K-Dense-AI/scientific-agent-skills48k1 repo~2.6kAutomated safety check: PassBSD-3-Clause2 days ago
11

Omics and single-cell workflow guide for AnnData, Scanpy-style dataset profiling, PyDESeq2-oriented count checks, pysam alignment inspection, and pyOpenMS mass-spectrometry summaries.

DrugClaw/DrugClaw125—~1.1kAutomated safety check: PassApache-2.06 mo ago
12

Annotated matrices for single-cell genomics. An agent skill from jaechang-hits/SciAgent-Skills.

jaechang-hits/SciAgent-Skills3702 repos~5.8kAutomated safety check: PassBSD-3-Clause8 days ago
13

Probabilistic single-cell RNA-seq with scvi-tools — scVI for a batch-corrected latent space, scANVI for semi-supervised label transfer, and Bayesian differential expression.

JimLiu/science-skills2274 repos~2.1kAutomated safety check: PassApache-2.03 mo ago
14

Handles annotated matrices in single-cell analysis, .h5ad and Zarr files, and integration with the scverse ecosystem.

K-Dense-AI/scientific-agent-skills48k1 repo~3.9kAutomated safety check: NotesBSD-3-Clause2 days ago
15

Local Scanpy pipeline for single-cell RNA-seq QC, optional doublet detection, clustering, marker discovery, optional CellTypist annotation, optional latent downstream mode from…

ClawBio/ClawBio1.2k1 repo~2.9kAutomated safety check: PassMITyesterday
16

Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions)…

GPTomics/bioSkills1.2k2 repos~4.8kAutomated safety check: PassMIT1 mo ago
17

Read, write, and create single-cell data objects using Seurat (R) and Scanpy (Python).

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~2kAutomated safety check: PassNo licence2 mo ago
18

Quality control, filtering, and normalization for single-cell RNA-seq using Seurat (R) and Scanpy (Python).

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~2.4kAutomated safety check: PassNo licence2 mo ago
19

Load spatial transcriptomics data from Visium, Xenium, MERFISH, Slide-seq, and other platforms using Squidpy and SpatialData.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repo~2kAutomated safety check: PassNo licence2 mo ago
20

RNA velocity analysis with scVelo. An agent skill from majiayu000/claude-skill-registry.

majiayu000/claude-skill-registry6665 repos~2.6kAutomated safety check: PassBSD-3-Clausetoday
21

Performs quality control on single-cell RNA-seq data (.h5ad or .h5 files) using scverse best practices with MAD-based filtering and comprehensive visualizations.

majiayu000/claude-skill-registry6663 repos~2kAutomated safety check: PassMITtoday
22

Reads, inspects, and writes Flow Cytometry Standard (FCS) files from conventional, spectral, and mass cytometry (CyTOF), and parses FlowJo/Cytobank/Diva workspaces.

GPTomics/bioSkills1.2k1 repo~2.5kAutomated safety check: PassMIT1 mo ago
23

Dimensionality reduction and graph-based clustering for single-cell RNA-seq with Scanpy (Python) and Seurat (R).

GPTomics/bioSkills1.2k1 repo~3.5kAutomated safety check: PassMIT1 mo ago
24

Detect cluster marker genes and assign manual cell type labels in single-cell RNA-seq using Scanpy (Python) and Seurat (R).

GPTomics/bioSkills1.2k1 repo~3.4kAutomated safety check: PassMIT1 mo ago
25

Quality control, ambient-RNA handling, normalization, and feature selection for single-cell RNA-seq using Scanpy (Python) and Seurat (R).

GPTomics/bioSkills1.2k1 repo~5.1kAutomated safety check: PassMIT1 mo ago
26

Quality control, filtering, and normalization for spatial transcriptomics (Visium, Visium HD, Xenium, MERFISH/MERSCOPE, CosMx, Slide-seq) with Squidpy and Scanpy.

GPTomics/bioSkills1.2k1 repo~4.7kAutomated safety check: PassMIT1 mo ago
27

Plots spatial transcriptomics expression, clusters, and annotations on tissue using Squidpy and Scanpy.

GPTomics/bioSkills1.2k1 repo~3.6kAutomated safety check: PassMIT1 mo ago
28

Orchestrates the end-to-end spatial transcriptomics pipeline from Space Ranger / vendor output to spatial domains and statistics, branching FIRST on platform class (imaging in-situ…

GPTomics/bioSkills1.2k1 repo~4.2kAutomated safety check: PassMIT1 mo ago
29

Open-source FAIR biology data framework. An agent skill from jaechang-hits/SciAgent-Skills.

jaechang-hits/SciAgent-Skills3702 repos~4kAutomated safety check: PassApache-2.08 days ago
30

Dimensionality reduction and clustering for single-cell RNA-seq using Seurat (R) and Scanpy (Python).

majiayu000/claude-skill-registry6662 repos~1.5kAutomated safety check: PassMITtoday
31

Find marker genes and annotate cell types in single-cell RNA-seq using Seurat (R) and Scanpy (Python).

majiayu000/claude-skill-registry6662 repos~1.9kAutomated safety check: PassMITtoday
32

Identify spatial domains and tissue regions in spatial transcriptomics data using Squidpy and Scanpy.

majiayu000/claude-skill-registry6662 repos~1.5kAutomated safety check: PassMITtoday
33

Visualize spatial transcriptomics data using Squidpy and Scanpy.

majiayu000/claude-skill-registry6662 repos~1.5kAutomated safety check: PassMITtoday
34

Primary retained Python toolkit for molecular biology sequence work.

foryourhealth111-pixel/Vibe-Skills3.6k—~3.5kAutomated safety check: PassApache-2.01 mo ago
35

Standard single-cell RNA-seq analysis pipeline. An agent skill from aipoch/medical-research-skills.

aipoch/medical-research-skills2k—~3.9kAutomated safety check: PassMIT20 days ago
36

Normalizes and transforms RNA-seq count matrices for DE, visualization, clustering, and ML.

GPTomics/bioSkills1.2k1 repo~6.2kAutomated safety check: PassMIT1 mo ago
37

Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <- CSR (Python) implicit…

GPTomics/bioSkills1.2k1 repo~5.6kAutomated safety check: PassMIT1 mo ago
38

scRNA-seq with Scanpy: QC, normalization, HVG selection, PCA, neighborhood graph, UMAP/t-SNE, Leiden clustering, markers, cell annotation, trajectory inference.

jaechang-hits/SciAgent-Skills3701 repo~4.7kAutomated safety check: PassCC-BY-4.08 days ago
39

Machine learning toolkit for genomic interval (BED) data; use it when you need to tokenize BED collections and train embeddings for regions/cells/labels, build consensus peak universes, or run…

aipoch/medical-research-skills2k—~1.9kAutomated safety check: PassMIT20 days ago
40

Harmony batch correction for scRNA-seq and other omics. An agent skill from jaechang-hits/SciAgent-Skills.

jaechang-hits/SciAgent-Skills3702 repos~5.6kAutomated safety check: PassMIT8 days ago
41

Multi-modal single-cell analysis with muon/MuData. An agent skill from jaechang-hits/SciAgent-Skills.

jaechang-hits/SciAgent-Skills3702 repos~8.1kAutomated safety check: PassBSD-3-Clause8 days ago
42

Load when ranking cluster-level marker genes from a clustered single-cell AnnData via Scanpy Wilcoxon / t-test / logreg or COSG specificity.

TianGzlab/OmicsClaw161—~1.2kAutomated safety check: PassMIT2 mo ago
43

Load when computing per-cell pathway / gene-set scores on a normalised scRNA AnnData via AUCell (R or Python) or Scanpy scoregenes.

TianGzlab/OmicsClaw161—~1.8kAutomated safety check: PassMIT2 mo ago
44

Load when normalising QC'd scRNA into a PCA-ready AnnData via scanpy / Seurat / SCTransform / Pearson residuals.

TianGzlab/OmicsClaw161—~1.4kAutomated safety check: PassMIT2 mo ago
45

Load when ranking spatial cluster markers or comparing two spatial groups in spatial transcriptomics.

TianGzlab/OmicsClaw161—~1.7kAutomated safety check: PassMIT2 mo ago
46

Local Scanpy pipeline for single-cell RNA-seq QC, clustering, marker discovery, and optional two-group differential expression from raw-count .h5ad.

FreedomIntelligence/OpenClaw-Medical-Skills3.1k—~1.7kAutomated safety check: PassMIT2 mo ago
47

Automated and marker-guided single-cell cell type annotation using CellTypist, marker review, reference transfer, and confidence-aware label curation.

BioTender-max/awesome-bio-agent-skills1971 repo~1.2kAutomated safety check: PassUnknown3 mo ago

Questions, answered from the data.

What is the best Scanpy skill?

Scanpy Single-Cell Analysis from davila7/claude-code-templates ranks first of the 47 Scanpy skills listed here, with the highest score: its repository has 32k GitHub stars, 16 other GitHub owners carry a copy, its SKILL.md loads about 2.8k tokens and it passes the automated safety check with no findings. Next come Single Cell Rna Analysis and Anndata.

Is there an official Scanpy skill?

None yet. All 47 Scanpy skills listed here come from community repositories; a skill counts as official when the product's own GitHub organization publishes it.

How are these skills ranked?

By Skill Navigator score, which combines the GitHub stars of the skill's repository (shared across that repo's skills and discounted for large collections), how many other GitHub owners carry a copy of the skill, and automated SKILL.md quality checks, minus penalties for safety-check warnings and for each further skill from the same repository. Skills that fail the safety check are not listed.