Automated and marker-guided single-cell cell type annotation using CellTypist, marker review, reference transfer, and confidence-aware label curation.

Custom licenceAuto-check passedResearch & Science

Install Cell Annotation

skills CLI
$ npx skills add BioTender-max/awesome-bio-agent-skills --skill cell-annotation -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install BioTender-max/awesome-bio-agent-skills cell-annotation --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/BioTender-max/awesome-bio-agent-skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bioclaw/cell-annotation .claude/skills/cell-annotation && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
cell-annotation
GitHub stars
197
Used in
1 other repo
Token cost
~1.2k tokens
SKILL.md length
469 words
Files
3
Skills in repo
18
Repo updated
First seen
Licence
Custom licence

At a glance

Automated and marker-guided single-cell cell type annotation using CellTypist, marker review, reference transfer, and confidence-aware label curation.

  • Works in 5 steps: Inspect markers before automation → Choose the annotation level → Run reference-based annotation → …
  • Tasks that involve Bioinformatics
  • SKILL.md covers Version Compatibility, Overview, When To Use This Skill and Quick Route, plus 12 more sections
  • Calls python

What it does

Cell Annotation is an agent skill from BioTender-max/awesome-bio-agent-skills. Automated and marker-guided single-cell cell type annotation using CellTypist, marker review, reference transfer, and confidence-aware label curation.

Its SKILL.md is about 1.2k tokens, which your agent loads only when the skill is triggered. The skill folder holds 2 other files (for example `commands_and_thresholds.md` and `technical_reference.md`).

It sits in Research & Science, covering Bioinformatics. It works with Scanpy. The repository describes itself as: A curated collection of AI agent skills for biomedical research, covering genomics, proteomics, single-cell analysis, clinical AI, and protein design.

When your agent uses it

  • Tasks that involve Bioinformatics

Example prompts

  • “/cell-annotation”

Requirements

  • Python 3

Workflow steps

5 steps, taken from the step headings in SKILL.md.

  1. Inspect markers before automation
  2. Choose the annotation level
  3. Run reference-based annotation
  4. Curate with markers and cluster context
  5. Export both raw and final labels

What it can do on your machine

Read from SKILL.md and the folder at commit 8cbdd18. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Shell commands in SKILL.md call:

    • python

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Cell Annotation loads about 1.2k tokens when it runs. Until then it costs about 42 tokens; SKILL.md has 469 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~42
When it runs · the whole SKILL.md, loaded when a task matches
~1.2k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Its licence (Custom licence) doesn't allow us to republish the file, so here is its outline and opening line. It has 469 words (~1,154 tokens).

name
cell-annotation
tool_type
python
primary_tool
CellTypist

Read the full SKILL.md on GitHub

Files

SKILL.md and 2 other files in skills/bioclaw/cell-annotation of BioTender-max/awesome-bio-agent-skills.

  • SKILL.md
  • commands_and_thresholds.md
  • technical_reference.md

Open the folder on GitHubat commit 8cbdd18

Used in 1 other repository

We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in BioTender-max/awesome-bio-agent-skills, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Cell Annotation next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Cell Annotation compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Cell Annotation this skillBioTender-max/awesome-bio-agent-skills1971 repos~1.2kAutomated safety check: PassCustom licence
Scanpy Single-Cell Analysisdavila7/claude-code-templates32k16 repos~2.8kAutomated safety check: PassMIT
Single Cell Rna AnalysisPKU-YuanGroup/OpenAI4S617—~1.3kAutomated safety check: PassMIT
Anndatadavila7/claude-code-templates32k12 repos~2.5kAutomated safety check: PassMIT
Cellxgene Censusdavila7/claude-code-templates32k11 repos~3.8kAutomated safety check: PassMIT
Sc MarkersTianGzlab/OmicsClaw1611 repos~2.2kAutomated safety check: PassApache-2.0

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    Walks through single-cell RNA-seq analysis with Scanpy: loading .h5ad and 10X data, QC, normalization, PCA and UMAP, Leiden clustering, marker genes and cell type annotation.

    32k GitHub starsUsed in 16 repos~2.8k tokens
    Research & ScienceAuto-check passed
  • Single Cell Rna Analysis

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Works with

Questions about Cell Annotation

What does Cell Annotation do?

Automated and marker-guided single-cell cell type annotation using CellTypist, marker review, reference transfer, and confidence-aware label curation. Cell Annotation is an agent skill from BioTender-max/awesome-bio-agent-skills. Automated and marker-guided single-cell cell type annotation using CellTypist, marker review, reference transfer, and confidence-aware label curation.

When should I use Cell Annotation?

Cell Annotation fits situations like: tasks that involve Bioinformatics.

How do I install Cell Annotation in Claude Code?

Run `npx skills add BioTender-max/awesome-bio-agent-skills --skill cell-annotation -a claude-code`. Or copy the skill folder (skills/bioclaw/cell-annotation in BioTender-max/awesome-bio-agent-skills) into .claude/skills/cell-annotation in your project. Claude Code loads it when a task matches its description.

How do I install Cell Annotation in Codex?

Run `npx skills add BioTender-max/awesome-bio-agent-skills --skill cell-annotation -a codex`. Or copy the skill folder (skills/bioclaw/cell-annotation in BioTender-max/awesome-bio-agent-skills) into .agents/skills/cell-annotation in your project. Codex loads it when a task matches its description.

Can I use Cell Annotation in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add BioTender-max/awesome-bio-agent-skills --skill cell-annotation -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/cell-annotation, .gemini/skills/cell-annotation, .github/skills/cell-annotation and .opencode/skills/cell-annotation in your project.

What does Cell Annotation need to run?

Going by SKILL.md and its folder, Cell Annotation needs the command-line tools its instructions call (python). Our summary lists: Python 3.

Does Cell Annotation access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Cell Annotation safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Cell Annotation use?

Cell Annotation has a licence file (the repository's licence) that doesn't match a standard licence. Read it on GitHub before reusing the skill.

How many tokens does Cell Annotation use?

About 1.2k tokens (SKILL.md is roughly 4.6k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Cell Annotation?

Skills that share tags, products or a category with Cell Annotation: Scanpy Single-Cell Analysis (davila7/claude-code-templates, 32k stars), Single Cell Rna Analysis (PKU-YuanGroup/OpenAI4S, 617 stars), Anndata (davila7/claude-code-templates, 32k stars) and Cellxgene Census (davila7/claude-code-templates, 32k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Cell Annotation?

BioTender-max (a GitHub user) maintains it in BioTender-max/awesome-bio-agent-skills, which has 197 GitHub stars. The repository holds 18 skills in this directory. The repository was last updated on July 1, 2026.

Source: BioTender-max/awesome-bio-agent-skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.