Agent skill

Ensembl Sequence Retrieval

by InternScience in InternScience/scp

Retrieve genomic sequences from Ensembl database using transcript or gene IDs to obtain nucleotide and protein sequences.

MITAuto-check passedResearch & Science

Install Ensembl Sequence Retrieval

skills CLI
$ npx skills add InternScience/scp --skill ensembl-sequence-retrieval -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install InternScience/scp ensembl-sequence-retrieval --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/ensembl-sequence-retrieval .claude/skills/ensembl-sequence-retrieval && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
ensembl-sequence-retrieval
GitHub stars
169
Used in
1 other repo
Token cost
~746 tokens
SKILL.md length
47 words
Files
1
Skills in repo
73
Repo updated
First seen
Licence
MIT

At a glance

Retrieve genomic sequences from Ensembl database using transcript or gene IDs to obtain nucleotide and protein sequences.

  • Works in 2 steps: MCP Server Definition → Sequence Retrieval Workflow
  • Tasks that involve Bioinformatics
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Ensembl Sequence Retrieval is an agent skill from InternScience/scp. Retrieve genomic sequences from Ensembl database using transcript or gene IDs to obtain nucleotide and protein sequences.

Its SKILL.md is about 750 tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.

It sits in Research & Science, covering Bioinformatics. It works with Ensembl. The licence is MIT.

When your agent uses it

  • Tasks that involve Bioinformatics

Example prompts

  • “/ensembl-sequence-retrieval”

Requirements

  • Python 3

Workflow steps

2 steps, taken from the step headings in SKILL.md.

  1. MCP Server Definition
  2. Sequence Retrieval Workflow

What it can do on your machine

Read from SKILL.md and the folder at commit cea5398. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md (its code samples are python).

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Ensembl Sequence Retrieval loads about 746 tokens when it runs. Until then it costs about 37 tokens; SKILL.md has 47 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~37
When it runs · the whole SKILL.md, loaded when a task matches
~746

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from InternScience/scp at commit cea5398, republished under its MIT licence (© InternScience). 47 words, ~746 tokens.

Download SKILL.mdSave it as .claude/skills/ensembl-sequence-retrieval/SKILL.md (or your agent's skills folder).
name
ensembl-sequence-retrieval
description
Retrieve genomic sequences from Ensembl database using transcript or gene IDs to obtain nucleotide and protein sequences.
license
MIT license
metadata.skill-author
PJLab

Ensembl Sequence Retrieval

Usage

1. MCP Server Definition
python
import asyncio
import json
from mcp.client.streamable_http import streamablehttp_client
from mcp import ClientSession

class OrigeneClient:
    """Origene-Ensembl MCP Client"""

    def __init__(self, server_url: str, api_key: str):
        self.server_url = server_url
        self.api_key = api_key
        self.session = None

    async def connect(self):
        try:
            self.transport = streamablehttp_client(
                url=self.server_url,
                headers={"SCP-HUB-API-KEY": self.api_key}
            )
            self.read, self.write, self.get_session_id = await self.transport.__aenter__()
            self.session_ctx = ClientSession(self.read, self.write)
            self.session = await self.session_ctx.__aenter__()
            await self.session.initialize()
            return True
        except Exception as e:
            print(f"✗ connect failure: {e}")
            return False

    async def disconnect(self):
        try:
            if self.session:
                await self.session_ctx.__aexit__(None, None, None)
            if hasattr(self, 'transport'):
                await self.transport.__aexit__(None, None, None)
        except Exception as e:
            print(f"✗ disconnect error: {e}")

    def parse_result(self, result):
        if isinstance(result, dict):
            content_list = result.get("content") or []
        else:
            content_list = getattr(result, "content", []) or []
        texts = []
        for item in content_list:
            if isinstance(item, dict):
                if item.get("type") == "text":
                    texts.append(item.get("text") or "")
            else:
                if getattr(item, "type", None) == "text":
                    texts.append(getattr(item, "text", "") or "")
        return "".join(texts)
2. Sequence Retrieval Workflow

Implementation:

python
## Initialize client
client = OrigeneClient(
    "https://scp.intern-ai.org.cn/api/v1/mcp/12/Origene-Ensembl",
    "<your-api-key>"
)

if not await client.connect():
    print("connection failed")
    exit()

## Retrieve sequence by Ensembl ID
result = await client.session.call_tool(
    "get_sequence_id",
    arguments={
        "id": "ENST00000380152"
    }
)

result_data = client.parse_result(result)
print(result_data)

await client.disconnect()
Tool Descriptions

Origene-Ensembl Server:

  • get_sequence_id: Retrieve sequence by Ensembl ID
    • Args:
      • id (str): Ensembl transcript or gene ID
    • Returns: Genomic or protein sequence
Use Cases
  • Genome annotation
  • Comparative genomics
  • Transcript analysis
  • Protein sequence retrieval

© InternScience, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

Just SKILL.md in skills/ensembl-sequence-retrieval of InternScience/scp.

Open the folder on GitHubat commit cea5398

Used in 2 other repositories

We found 2 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in InternScience/scp, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Ensembl Sequence Retrieval next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Ensembl Sequence Retrieval compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Ensembl Sequence Retrieval this skillInternScience/scp1691 repos~746Automated safety check: PassMIT
External API ChangeGuyTeichman/RNAlysis140—~1.8kAutomated safety check: PassMIT
Ensembl Databasedavila7/claude-code-templates32k10 repos~2.1kAutomated safety check: PassMIT
Annotating Variantsmaziyarpanahi/openmed5.5k—~2.1kAutomated safety check: PassApache-2.0
Ggetdavila7/claude-code-templates32k11 repos~6.3kAutomated safety check: PassMIT
Ensembl Databasegoogle-deepmind/science-skills3.2k1 repos~2.2kAutomated safety check: PassApache-2.0

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  • External API Change

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  • Ensembl Database

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    32k GitHub starsUsed in 11 repos~6.3k tokens
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  • Ensembl Database

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  • gget CLI and Python workflow for quick genomic database queries, sequence lookup, BLAST-style searches, enrichment checks, and reproducible bioinformatics evidence logs.

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Works with

Questions about Ensembl Sequence Retrieval

What does Ensembl Sequence Retrieval do?

Retrieve genomic sequences from Ensembl database using transcript or gene IDs to obtain nucleotide and protein sequences. Ensembl Sequence Retrieval is an agent skill from InternScience/scp. Retrieve genomic sequences from Ensembl database using transcript or gene IDs to obtain nucleotide and protein sequences.

When should I use Ensembl Sequence Retrieval?

Ensembl Sequence Retrieval fits situations like: tasks that involve Bioinformatics.

How do I install Ensembl Sequence Retrieval in Claude Code?

Run `npx skills add InternScience/scp --skill ensembl-sequence-retrieval -a claude-code`. Or copy the skill folder (skills/ensembl-sequence-retrieval in InternScience/scp) into .claude/skills/ensembl-sequence-retrieval in your project. Claude Code loads it when a task matches its description.

How do I install Ensembl Sequence Retrieval in Codex?

Run `npx skills add InternScience/scp --skill ensembl-sequence-retrieval -a codex`. Or copy the skill folder (skills/ensembl-sequence-retrieval in InternScience/scp) into .agents/skills/ensembl-sequence-retrieval in your project. Codex loads it when a task matches its description.

Can I use Ensembl Sequence Retrieval in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add InternScience/scp --skill ensembl-sequence-retrieval -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/ensembl-sequence-retrieval, .gemini/skills/ensembl-sequence-retrieval, .github/skills/ensembl-sequence-retrieval and .opencode/skills/ensembl-sequence-retrieval in your project.

What does Ensembl Sequence Retrieval need to run?

SKILL.md names no scripts, command-line tools or credentials: Ensembl Sequence Retrieval is instructions for the agent only. Our summary lists: Python 3.

Does Ensembl Sequence Retrieval access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Ensembl Sequence Retrieval safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Ensembl Sequence Retrieval use?

Ensembl Sequence Retrieval is published under the MIT licence (declared in SKILL.md). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Ensembl Sequence Retrieval use?

About 746 tokens (SKILL.md is roughly 3k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Ensembl Sequence Retrieval?

Skills that share tags, products or a category with Ensembl Sequence Retrieval: External API Change (GuyTeichman/RNAlysis, 140 stars), Ensembl Database (davila7/claude-code-templates, 32k stars), Annotating Variants (maziyarpanahi/openmed, 5.5k stars) and Gget (davila7/claude-code-templates, 32k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Ensembl Sequence Retrieval?

InternScience (a GitHub organization) maintains it in InternScience/scp, which has 169 GitHub stars. The repository holds 73 skills in this directory. The repository was last updated on June 3, 2026.

Source: InternScience/scp on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.