Agent skill

Response Letter

by aipoch in aipoch/medical-research-skills

Helps organize reviewer comments and generate a standardized Word (.docx) response letter that maps each change to its exact location (page/paragraph/line).

MITAuto-check passedDocuments & Office

Install Response Letter

skills CLI
$ npx skills add aipoch/medical-research-skills --skill response-letter -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install aipoch/medical-research-skills response-letter --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/aipoch/medical-research-skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/'scientific-skills/Academic Writing/response-letter' .claude/skills/response-letter && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
response-letter
GitHub stars
2k
Token cost
~2.1k tokens
SKILL.md length
890 words
Files
5 (incl. references, assets)
Skills in repo
578
Repo updated
First seen
Licence
MIT

At a glance

Helps organize reviewer comments and generate a standardized Word (.docx) response letter that maps each change to its exact location (page/paragraph/line).

  • Works in 3 steps: Thanks the reviewer for the comment → Points to the relevant section… → Quotes the relevant passage as a…
  • Revising a manuscript
  • SKILL.md covers When to Use, Key Features, Dependencies and Example Usage, plus 8 more sections
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Response Letter is an agent skill from aipoch/medical-research-skills. Helps organize reviewer comments and generate a standardized Word (.docx) response letter that maps each change to its exact location (page/paragraph/line). Use when revising a manuscript, replying to peer-review feedback, or preparing internal review responses.

Its SKILL.md is about 2.1k tokens, which your agent loads only when the skill is triggered. The skill folder holds 6 other files, including reference files and assets (for example `POLISH_CHANGELOG.md`, `eval_report_response-letter_result.json` and `references/guide.md`).

It sits in Documents & Office, covering Word documents, Programmatic SEO and Peer review. It works with Microsoft Word. The repository describes itself as: Hundreds of agent skills for medical research, including protocol design, data analysis, evidence insights, and academic writing. The licence is MIT.

When your agent uses it

  • Revising a manuscript
  • Replying to peer-review feedback
  • Preparing internal review responses

Example prompts

  • “Use the response-letter skill to help organize reviewer comments and generate a standardized Word (.docx) response letter that maps each change to…”
  • “/response-letter”

Workflow steps

3 steps, taken from the first numbered list in SKILL.md.

  1. Thanks the reviewer for the comment
  2. Points to the relevant section (page/paragraph/line) where the information already exists
  3. Quotes the relevant passage as a blockquote

What it can do on your machine

Read from SKILL.md and the folder at commit 686e09d. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md.

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Response Letter loads about 2.1k tokens when it runs, and up to ~2.3k if it reads all its reference files. Until then it costs about 70 tokens; SKILL.md has 890 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~70
When it runs · the whole SKILL.md, loaded when a task matches
~2.1k
With references · SKILL.md plus every file in references/, read only if the agent opens them
~2.3k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from aipoch/medical-research-skills at commit 686e09d, republished under its MIT licence (© aipoch). 890 words, ~2,115 tokens.

Download SKILL.mdSave it as .claude/skills/response-letter/SKILL.md (or your agent's skills folder). This skill also uses 4 other files; get the full folder from GitHub.
name
response-letter
description
Helps organize reviewer comments and generate a standardized Word (.docx) response letter that maps each change to its exact location (page/paragraph/line). Use when revising a manuscript, replying to peer-review feedback, or preparing internal review responses.
license
MIT
author
AIPOCH

Source: https://github.com/aipoch/medical-research-skills

When to Use

  • You received peer-review comments and need a point-by-point response letter for journal resubmission.
  • You must clearly map every manuscript change to a specific location (page/paragraph/line) for reviewers or editors.
  • You need a consistent, professional response structure across multiple reviewers and revision rounds.
  • You are coordinating an internal review and want a standardized change log and execution checklist.
  • You need a Word (.docx) deliverable rather than a table-based response format.

Key Features

  • Consolidates, merges, and numbers reviewer comments across reviewers.
  • Separates major vs. minor comments to prioritize revision work.
  • Produces a fixed, repeatable response layout per comment:
    • Reviewer’s Comment
    • Response
    • Changes in Text
  • Requires explicit change-location marking (page/paragraph/line) and version labeling.
  • Supports quoting revised manuscript text (e.g., blockquotes) to make changes auditable.
  • Generates a Word (.docx) response letter plus a modification/execution checklist.
  • Adds an Overview for the Editor section summarizing major revisions at the beginning.
  • Enforces a professional, polite tone throughout.

Dependencies

  • Microsoft Word .docx output (Word-compatible document generation)
  • Reference format guide: references/guide.md
  • Response template: assets/review_response_template.docx

Example Usage

text
Input:
- Manuscript (tracked version or clean version + change notes)
- Reviewer comments (all reviewers, all rounds)
- Current manuscript pagination/line numbering scheme (if available)

Steps:
1) Organize comments
   - Merge all reviewer comments into a single list.
   - Number them sequentially (e.g., R1-1, R1-2…; R2-1…).
   - Tag each as Major or Minor.

2) Draft "Overview for the Editor"
   - Write one concise paragraph summarizing the major revisions and their rationale.

3) Write point-by-point responses
   For each numbered comment, output:
   - Reviewer’s Comment: (verbatim or lightly cleaned for clarity)
   - Response: (polite, direct, addresses the request)
   - Changes in Text: (what changed + where)

4) Mark locations and quote revised text
   - Provide page/paragraph/line for each change.
   - Specify additions/deletions.
   - Quote the revised paragraph when the main text is modified.

5) Generate deliverables
   - Export the full response letter as a Word document (.docx).
   - Produce a modification/execution checklist to verify all changes are applied.

Output (Word .docx structure):
- Title / Manuscript info (optional)
- Overview for the Editor
- Responses to Reviewer 1
  - R1-1
  - R1-2
  ...
- Responses to Reviewer 2
  ...
- Modification / Execution Checklist

Implementation Details

  • Comment normalization and numbering
    • Merge comments from all sources; assign stable IDs (e.g., R{reviewer}-{index}) to preserve traceability across revision rounds.
  • Major vs. minor classification
    • Major: requests affecting study design, analyses, interpretation, or core claims.
    • Minor: wording, formatting, clarifications, citations, typos.
  • Per-comment fixed layout
    • Each response must include three labeled blocks: Reviewer’s Comment, Response, Changes in Text.
  • Location marking
    • Use page/paragraph/line when available; otherwise use section/subsection headings plus paragraph index.
    • Always indicate whether text was added, deleted, or rewritten.
  • Revised-text excerpting
    • When the manuscript body changes, include the updated paragraph as an indented blockquote under Changes in Text for auditability.
  • Output constraints
    • Final deliverable is a Word document (.docx).
    • Do not use table format for the response letter.
  • Formatting and checklists
    • Follow references/guide.md for required output formats, checklist items, and key writing points.

When Not to Use

  • Do not proceed when required input files, identifiers, parameters, or context are missing — ask the user to provide them first.
  • Do not assume capabilities beyond this skill's declared scope when the user requests external operations or inferences.
  • Do not proceed without user confirmation when overwriting existing results, executing high-cost batch operations, or expanding task scope.

Required Inputs

FieldRequiredFormat/SourceExampleIf Missing
User task descriptionYesTextResearch question, writing goal, analysis objectiveStop and ask user to provide
Primary input materialDepends on taskText, file path, ID, table, or literaturePMID, PDF, CSV, DOCX, keywords, etc.Specify which material type is missing
Output preferenceNoTextLanguage, format, target journal, templateUse skill default format

Output Contract

  • Primary output: Structured result or target file aligned with this skill's objective.
  • Optional output: Intermediate check notes, issue list, supplementary suggestions, or generated file paths.
  • Format requirement: Unless the user specifies otherwise, prefer stable, reviewable Markdown or JSON; if the skill's bundled script requires a fixed format, use that format.
  • If partially complete: Must explicitly mark as PARTIAL and state which steps are completed and which remain.

Failure Handling

  • Missing critical input: Explicitly state which fields, files, or identifiers are missing and pause.
  • Script, template, or resource execution failure: Report the failing step, likely cause, and recovery suggestions — do not silently degrade.
  • Partial completion only: Return the verified portion first, then list remaining blockers and suggested next steps.
Show full SKILL.md (342 more words)Show less

User Checkpoints

Checkpoint 1: Before Drafting Overview
  • After reading all reviewer comments, summarize the major revision themes and present them to the user.
  • Ask: "Here are the main revision areas I identified. Do you want me to include all in the Editor Overview, or focus on specific points?"
  • Wait for user confirmation before writing the Overview for the Editor.
Checkpoint 2: Before Generating DOCX
  • After drafting all point-by-point responses, summarize the total number of responses, major vs minor split, and any potentially sensitive replies (e.g., politely disagreeing with a reviewer).
  • Ask: "I have drafted N responses (X major, Y minor). Do you want me to proceed to generate the final DOCX, or would you like to review/edit any responses first?"
  • Wait for user confirmation before generating the deliverable.
Checkpoint 3: Edge Case — Reviewer Comment is Incorrect or Based on a Misreading
  • If a reviewer's comment appears to misunderstand the manuscript, do NOT skip it.
  • Draft a polite response that:
    1. Thanks the reviewer for the comment
    2. Points to the relevant section (page/paragraph/line) where the information already exists
    3. Quotes the relevant passage as a blockquote
  • Present this draft to the user for review before including in the final letter, as tone is critical here.
Checkpoint 4: Multiple Review Rounds
  • If the user provides comments from multiple revision rounds (R1, R2, etc.), ask how they want to organize: separate sections per round, or a combined response.

Input Validation

This skill accepts requests that match the documented purpose of response-letter and include enough context to complete the workflow safely.

Do not continue the workflow when the request is out of scope, missing a critical input, or would require unsupported assumptions. Instead respond:

response-letter only handles its documented workflow. Please provide the missing required inputs or switch to a more suitable skill.

Quick Validation

  • Check that key scripts, templates, or reference file paths this skill depends on exist.
  • Check that the final output contains the core fields, sections, or files specified for this task.
  • Check that results clearly mark assumptions, limitations, and incomplete items.

© aipoch, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

SKILL.md and 4 other files (references, assets) in scientific-skills/Academic Writing/response-letter of aipoch/medical-research-skills.

  • SKILL.md
  • POLISH_CHANGELOG.md
  • assets/review_response_template.docx
  • eval_report_response-letter_result.json
  • references/guide.md

Open the folder on GitHubat commit 686e09d

Compare with similar skills

Response Letter next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Response Letter compared with similar skills
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Response Letter this skillaipoch/medical-research-skills2k—~2.1kAutomated safety check: PassMIT
Review Papermaxwell2732/my-submission-formatting-agent111—~1.2kAutomated safety check: PassNone
AI Review SkillNeuroDong/Ai-Review626—~2.5kAutomated safety check: PassMIT
Nature Review Studiomumdark/nature-review-studio145—~974Automated safety check: PassNone
Paper CovertGRIND-Lab-Core/night_owl_research_agent106—~2.1kAutomated safety check: NotesNone
Cell Reviewyrui-cmd/Cell106—~2.5kAutomated safety check: PassMIT

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Works with

Questions about Response Letter

What does Response Letter do?

Helps organize reviewer comments and generate a standardized Word (.docx) response letter that maps each change to its exact location (page/paragraph/line). Response Letter is an agent skill from aipoch/medical-research-skills.docx) response letter that maps each change to its exact location (page/paragraph/line).

When should I use Response Letter?

Response Letter fits situations like: revising a manuscript; replying to peer-review feedback; preparing internal review responses.

How do I install Response Letter in Claude Code?

Run `npx skills add aipoch/medical-research-skills --skill response-letter -a claude-code`. Or copy the skill folder (scientific-skills/Academic Writing/response-letter in aipoch/medical-research-skills) into .claude/skills/response-letter in your project. Claude Code loads it when a task matches its description.

How do I install Response Letter in Codex?

Run `npx skills add aipoch/medical-research-skills --skill response-letter -a codex`. Or copy the skill folder (scientific-skills/Academic Writing/response-letter in aipoch/medical-research-skills) into .agents/skills/response-letter in your project. Codex loads it when a task matches its description.

Can I use Response Letter in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add aipoch/medical-research-skills --skill response-letter -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/response-letter, .gemini/skills/response-letter, .github/skills/response-letter and .opencode/skills/response-letter in your project.

What does Response Letter need to run?

SKILL.md names no scripts, command-line tools or credentials: Response Letter is instructions for the agent only.

Does Response Letter access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Response Letter safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Response Letter use?

Response Letter is published under the MIT licence (declared in SKILL.md). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Response Letter use?

About 2.1k tokens (SKILL.md is roughly 8.5k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 234 tokens, read only when the agent opens those files.

What are the alternatives to Response Letter?

Skills that share tags, products or a category with Response Letter: Review Paper (maxwell2732/my-submission-formatting-agent, 111 stars), AI Review Skill (NeuroDong/Ai-Review, 626 stars), Nature Review Studio (mumdark/nature-review-studio, 145 stars) and Paper Covert (GRIND-Lab-Core/night_owl_research_agent, 106 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Response Letter?

aipoch (a GitHub organization) maintains it in aipoch/medical-research-skills, which has 1,978 GitHub stars. The repository holds 578 skills in this directory. The repository was last updated on September 17, 2026.

Source: aipoch/medical-research-skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.