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Bioinformatics
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| # | Skill | Repository | Stars | Used in | Tokens | Auto-check | Licence | Updated |
|---|---|---|---|---|---|---|---|---|
| 145 | gget CLI and Python workflow for quick genomic database queries, sequence lookup, BLAST-style searches, enrichment checks, and reproducible bioinformatics evidence logs. | affaan-m/ | 277k | 1 repo | ~1.3k | Automated safety check: Pass | MIT | today |
| 146 | The Bandle package enables the analysis and visualisation of differential localisation experiments using mass-spectrometry data. | bioMate-AI/ | 804 | — | ~1.3k | Automated safety check: Pass | Unknown | 3 mo ago |
| 147 | 147.Genomi Decode Activate this skill for "/genomi decode", "decode my genome", "decode my DNA", "show me the dashboard", "the Genomi dashboard", "one-shot rundown", or any all-at-once request that asks Genomi to… | exon-research/ | 484 | — | ~2k | Automated safety check: Pass | Apache-2.0 | 1 mo ago |
| 148 | Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. | GPTomics/ | 1.2k | 2 repos | ~4.3k | Automated safety check: Pass | MIT | 1 mo ago |
| 149 | Shotgun metagenomics profiling — taxonomy, resistome, and functional pathways | ClawBio/ | 1.2k | 3 repos | ~2.4k | Automated safety check: Pass | MIT | 2 days ago |
| 150 | 150.Polars Bio Fast genomic interval operations (overlap, nearest, merge, coverage, cluster, complement, subtract, count-overlaps), multi-format bioinformatics I/O, DataFusion SQL, and pileup on Polars DataFrames… | ClawBio/ | 1.2k | — | ~3.4k | Automated safety check: Pass | Apache-2.0 | 2 days ago |
| 151 | 151.Bioservices Provides a Python interface to bioinformatics services including UniProt, KEGG, ChEMBL, Reactome, QuickGO, and UniChem. | K-Dense-AI/ | 48k | 1 repo | ~3k | Automated safety check: Notes | MIT | 6 days ago |
| 152 | 152.Cellxgene Census Queries the CZ CELLxGENE Census programmatically for versioned public single-cell and spatial transcriptomics data. | K-Dense-AI/ | 48k | 1 repo | ~3.4k | Automated safety check: Notes | MIT | 6 days ago |
| 153 | Builds and operates reproducible genomics workloads on DNAnexus with the dx CLI, dxpy, apps/applets, native workflows, dxCompiler, and Nextflow. | K-Dense-AI/ | 48k | 1 repo | ~3.1k | Automated safety check: Pass | MIT | 6 days ago |
| 154 | 154.Etetoolkit Analyzes, manipulates, compares, annotates, and visualizes phylogenetic or other hierarchical trees with ETE 4. | K-Dense-AI/ | 48k | 1 repo | ~3.3k | Automated safety check: Notes | GPL-3.0-or-later | 6 days ago |
| 155 | 155.Geniml Supports audited local Geniml genomic-interval workflows: validate BED and universe contracts, plan Region2Vec or scEmbed runs, inspect model/tokenizer compatibility, and assess consensus universes. | K-Dense-AI/ | 48k | 1 repo | ~4k | Automated safety check: Notes | MIT | 6 days ago |
| 156 | 156.Gget Queries 20+ bioinformatics resources through CLI/Python. An agent skill from K-Dense-AI/scientific-agent-skills. | K-Dense-AI/ | 48k | 1 repo | ~2.8k | Automated safety check: Notes | BSD-2-Clause | 6 days ago |
| 157 | 157.Gtars Supports Gtars for local genomic interval models and set algebra, overlaps and counts, consensus and coverage, tokenization, fragment processing, and refget/BEDbase planning across Python, Rust, and… | K-Dense-AI/ | 48k | 1 repo | ~3.8k | Automated safety check: Notes | MIT | 6 days ago |
| 158 | 158.Hugging Science Discovers and evaluates scientific datasets, models, methodology posts, and Spaces through the Hugging Science catalog. | K-Dense-AI/ | 48k | 1 repo | ~2.9k | Automated safety check: Notes | MIT | 6 days ago |
| 159 | 159.Phylogenetics Builds and analyzes phylogenetic trees using MAFFT multiple sequence alignment, IQ-TREE maximum likelihood with ModelFinder and branch support, and FastTree approximate inference. | K-Dense-AI/ | 48k | 1 repo | ~2.3k | Automated safety check: Pass | MIT | 6 days ago |
| 160 | 160.Polars Bio Performs genomic interval overlap, nearest, merge, coverage, complement and subtraction on Polars DataFrames, and reads or writes BED, VCF, BCF, BAM, CRAM, GFF, GTF, FASTA and FASTQ data. | K-Dense-AI/ | 48k | 1 repo | ~3.2k | Automated safety check: Notes | Apache-2.0 | 6 days ago |
| 161 | 161.Pyopenms Processes mass spectrometry data with pyOpenMS. An agent skill from K-Dense-AI/scientific-agent-skills. | K-Dense-AI/ | 48k | 1 repo | ~3.1k | Automated safety check: Notes | BSD-3-Clause | 6 days ago |
| 162 | 162.Pysam Provides Python/HTSlib workflows for genomic files. An agent skill from K-Dense-AI/scientific-agent-skills. | K-Dense-AI/ | 48k | 1 repo | ~3.4k | Automated safety check: Notes | MIT | 6 days ago |
| 163 | 163.Scvi Tools Fits probabilistic models for single-cell omics, including scVI batch integration, scANVI annotation, totalVI CITE-seq, MultiVI RNA/ATAC integration, and posterior differential expression. | K-Dense-AI/ | 48k | 1 repo | ~2.6k | Automated safety check: Pass | BSD-3-Clause | 6 days ago |
| 164 | 164.Tiledbvcf Stores and retrieves genomic variant calls with TileDB-VCF. An agent skill from K-Dense-AI/scientific-agent-skills. | K-Dense-AI/ | 48k | 1 repo | ~3.5k | Automated safety check: Pass | MIT | 6 days ago |
| 165 | Stage 5 of the spatial transcriptomics workflow — neighborhood enrichment and cell-cell communication analysis. | QING1105/ | 101 | — | ~513 | Automated safety check: Pass | MIT | 1 mo ago |
| 166 | 166.Omics Tools Omics and single-cell workflow guide for AnnData, Scanpy-style dataset profiling, PyDESeq2-oriented count checks, pysam alignment inspection, and pyOpenMS mass-spectrometry summaries. | DrugClaw/ | 126 | — | ~1.1k | Automated safety check: Pass | Apache-2.0 | 6 mo ago |
| 167 | Load when running pathway / GO term enrichment on a bulk RNA-seq DE result list. | TianGzlab/ | 161 | — | ~860 | Automated safety check: Pass | Apache-2.0 | 4 days ago |
| 168 | A skill your agent uses when a developer asks how to get started building healthcare or life sciences agents, wants to understand the HCLS Agents Toolkit, or asks what's available in this repository. | aws-samples/ | 274 | — | ~607 | Automated safety check: Pass | MIT-0 | 9 days ago |
| 169 | 169.Bioinformatics Gateway to 400+ bioinformatics skills from bioSkills and ClawBio. | Tommy-yw/ | 546 | 3 repos | ~3.4k | Automated safety check: Notes | MIT | 4 mo ago |
| 170 | Implements a variety of methods for batch correction of single-cell (RNA sequencing) data. | bioMate-AI/ | 804 | — | ~4.3k | Automated safety check: Pass | Unknown | 3 mo ago |
| 171 | 171.Repro Enforcer Export any bioinformatics analysis as a reproducible bundle with Conda environment, Singularity container definition, and Nextflow pipeline. | ClawBio/ | 1.2k | 3 repos | ~413 | Automated safety check: Pass | MIT | 2 days ago |
| 172 | Predicts regulatory features, gene structure, and expression directly from DNA sequence using Genomic Intelligence's hosted transformer DNA language models — no local GPU or model weights. | K-Dense-AI/ | 48k | 1 repo | ~6.2k | Automated safety check: Notes | MIT | 6 days ago |
| 173 | 173.Scvi Tools Probabilistic single-cell RNA-seq with scvi-tools — scVI for a batch-corrected latent space, scANVI for semi-supervised label transfer, and Bayesian differential expression. | JimLiu/ | 228 | 4 repos | ~2.1k | Automated safety check: Pass | Apache-2.0 | 3 mo ago |
| 174 | ATAC-seq library quality control -- TSS enrichment, FRiP, fragment-size periodicity, library complexity (NRF/PBC1/PBC2), mitochondrial fraction, and ENCODE 4 thresholds. | GPTomics/ | 1.2k | 2 repos | ~5k | Automated safety check: Pass | MIT | 1 mo ago |
| 175 | 175.Genome Compare Compare your genome to George Church (PGP-1) and estimate ancestry composition via IBS and EM admixture | ClawBio/ | 1.2k | 2 repos | ~1.2k | Automated safety check: Pass | MIT | 2 days ago |
| 176 | 176.Galaxy Bridge Galaxy tool discovery, intelligent recommendation, and execution — 8,000+ bioinformatics tools from usegalaxy.org with multi-signal scoring and workflow suggestions | ClawBio/ | 1.2k | 2 repos | ~2.4k | Automated safety check: Pass | MIT | 2 days ago |
| 177 | 177.Gwas Lookup Federated variant lookup across 8 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ), GTEx, and more. | ClawBio/ | 1.2k | 2 repos | ~1.1k | Automated safety check: Pass | MIT | 2 days ago |
| 178 | 178.Profile Report Unified personal genomic profile report — reads a PatientProfile JSON and synthesizes all skill results into a single "Your Genomic Profile" document. | ClawBio/ | 1.2k | 2 repos | ~2.1k | Automated safety check: Pass | MIT | 2 days ago |
| 179 | 179.Spatial Visium Classic Visium platform branch of the spatial transcriptomics workflow — spot-level 5-stage pipeline (load+QC, normalize+cluster, domains+SVG, deconvolution, downstream prep). | QING1105/ | 101 | — | ~750 | Automated safety check: Pass | MIT | 1 mo ago |
| 180 | Load when converting Ensembl, Entrez or symbol IDs in a bulk RNA count matrix using an explicit mapping or a small human demo reference. | TianGzlab/ | 161 | — | ~1.2k | Automated safety check: Pass | Apache-2.0 | 4 days ago |
| 181 | 181.Biopython Provides Biopython workflows for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). | K-Dense-AI/ | 48k | 1 repo | ~4.3k | Automated safety check: Notes | MIT | 6 days ago |
| 182 | 182.Anndata Handles annotated matrices in single-cell analysis, .h5ad and Zarr files, and integration with the scverse ecosystem. | K-Dense-AI/ | 48k | 1 repo | ~3.9k | Automated safety check: Notes | BSD-3-Clause | 6 days ago |
| 183 | 183.Deepspot M Generates transcriptome-wide virtual spatial transcriptomics from H&E histology with DeepSpot-M. | K-Dense-AI/ | 48k | 1 repo | ~2.5k | Automated safety check: Notes | PolyForm-Noncommercial-1.0.0 | 6 days ago |
| 184 | A skill your agent uses when querying biomedical databases (UniProt, ClinVar, gnomAD, PDB, Reactome, Open Targets, etc.) via the Biomni AgentCore Gateway MCP server. | aws-samples/ | 274 | — | ~3.1k | Automated safety check: Pass | MIT-0 | 9 days ago |
| 185 | Annotated matrices for single-cell genomics. An agent skill from jaechang-hits/SciAgent-Skills. | jaechang-hits/ | 374 | 2 repos | ~5.8k | Automated safety check: Pass | BSD-3-Clause | 12 days ago |
| 186 | BEER implements a Bayesian model for analyzing phage-immunoprecipitation sequencing (PhIP-seq) data. | bioMate-AI/ | 804 | — | ~1.3k | Automated safety check: Pass | Unknown | 3 mo ago |
| 187 | Infer cis-regulatory connections (peak-to-peak co-accessibility) from scATAC-seq using Cicero, ArchR getCoAccessibility, or SCENIC+. | GPTomics/ | 1.2k | 2 repos | ~4.6k | Automated safety check: Pass | MIT | 1 mo ago |
| 188 | 188.Biopython Computational molecular biology library (sequence I/O, alignment, phylogenetics). | lamm-mit/ | 246 | — | ~3.9k | Automated safety check: Pass | Apache-2.0 | 1 mo ago |
| 189 | Generate and analyze DNA sequences using NVIDIA's Evo 2 BioNeMo NIM microservice. | NVIDIA/ | 3.6k | 1 repo | ~2.4k | Automated safety check: Notes | Apache-2.0 | 2 days ago |
| 190 | 190.Spatial Xenium Xenium platform branch of the spatial transcriptomics workflow — load and validate the platform's cell-level matrix for downstream analysis. | QING1105/ | 101 | — | ~535 | Automated safety check: Pass | MIT | 1 mo ago |
| 191 | Load when querying STRING for the protein-protein interaction neighborhood of a bulk RNA-seq DEG list and finding hub genes. | TianGzlab/ | 161 | — | ~1.2k | Automated safety check: Pass | Apache-2.0 | 4 days ago |
| 192 | Build/run/audit bulk RNA, sc/snRNA and spatial workflows with traceable QC; not mechanism claims. | huang-sir1/ | 1.9k | — | ~3.1k | Automated safety check: Pass | Unknown | 20 days ago |