Agent skill

Readout Handicap

by hh-health-AI in hh-health-AI/healthcare-equity

This skill should be used when the user says "handicap this readout", "pre-mortem the Phase 3", "what are the odds this trial works", "assess the trial design for [TICKER]", or before any binary…

MITAuto-check passedMarketing & SEO

Install Readout Handicap

skills CLI
$ npx skills add hh-health-AI/healthcare-equity --skill readout-handicap -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install hh-health-AI/healthcare-equity readout-handicap --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/hh-health-AI/healthcare-equity.git skills-src && mkdir -p .claude/skills && cp -r skills-src/modules/clinical-catalysts/skills/readout-handicap .claude/skills/readout-handicap && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
readout-handicap
GitHub stars
101
Token cost
~555 tokens
SKILL.md length
215 words
Files
2 (incl. references)
Skills in repo
72
Repo updated
First seen
Licence
MIT

At a glance

This skill should be used when the user says "handicap this readout", "pre-mortem the Phase 3", "what are the odds this trial works", "assess the trial design for [TICKER]", or before any binary…

  • Works in 6 steps: Pull the trial from the Clinical Trials… → Run the SUB-BIO-01 prompt (in… → Anchor probabilities in… → …
  • Says handicap this readout
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md
  • Pre-mortem the Phase 3

What it does

Readout Handicap is an agent skill from hh-health-AI/healthcare-equity. This skill should be used when the user says "handicap this readout", "pre-mortem the Phase 3", "what are the odds this trial works", "assess the trial design for [TICKER]", or before any binary clinical data event where probability of success and outcome scenarios drive positioning.

Its SKILL.md is about 560 tokens, which your agent loads only when the skill is triggered. The skill folder holds 2 other files, including reference files (for example `references/prompts.md`).

It sits in Marketing & SEO, covering Positioning and messaging and Clinical and healthcare research. The repository describes itself as: Synthesis engine for buy-side healthcare equity research. The licence is MIT.

When your agent uses it

  • Says handicap this readout
  • Pre-mortem the Phase 3
  • What are the odds this trial works
  • Assess the trial design for [TICKER]

Example prompts

  • “handicap this readout”
  • “pre-mortem the Phase 3”
  • “what are the odds this trial works”
  • “/readout-handicap”

Workflow steps

6 steps, taken from the first numbered list in SKILL.md.

  1. Pull the trial from the Clinical Trials connector: design (randomization, blinding, comparator, N, endpoints and hierarchy, powering…
  2. Run the SUB-BIO-01 prompt (in ${CLAUDE_PLUGIN_ROOT}/skills/readout-handicap/references/prompts.md): trial design → phase-transition base…
  3. Anchor probabilities in ${CLAUDE_PLUGIN_ROOT}/references/base-rates.md; adjust for indication-specific rates, endpoint quality (surrogate…
  4. Build the outcome distribution as mutually exclusive scenarios per the scenario discipline in…
  5. State the smart short's critique of the design (the criticisms a skeptic would raise) before concluding.
  6. End with the EVIDENCE BRIEF block (layer: clinical). Pass the PoS and scenario set to healthcare-equity model-valuation (MOD-03 rNPV) and…

What it can do on your machine

Read from SKILL.md and the folder at commit 6c7bda8. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md.

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Readout Handicap loads about 555 tokens when it runs, and up to ~767 if it reads all its reference files. Until then it costs about 75 tokens; SKILL.md has 215 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~75
When it runs · the whole SKILL.md, loaded when a task matches
~555
With references · SKILL.md plus every file in references/, read only if the agent opens them
~767

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from hh-health-AI/healthcare-equity at commit 6c7bda8, republished under its MIT licence (© hh-health-AI). 215 words, ~555 tokens.

Download SKILL.mdSave it as .claude/skills/readout-handicap/SKILL.md (or your agent's skills folder). This skill also uses 1 other file; get the full folder from GitHub.
name
readout-handicap
description
This skill should be used when the user says "handicap this readout", "pre-mortem the Phase 3", "what are the odds this trial works", "assess the trial design for [TICKER]", or before any binary clinical data event where probability of success and outcome scenarios drive positioning.
metadata.version
0.1.0

Readout Handicap

Handicap an upcoming clinical readout: audit the design, set base rates, decompose probability of success, and map outcome scenarios to positioning.

Workflow

  1. Pull the trial from the Clinical Trials connector: design (randomization, blinding, comparator, N, endpoints and hierarchy, powering assumptions where inferable), status and date history. Retrieve the prior-phase data (company disclosures, PubMed publication of the Phase 2) and any protocol publication. Note registry-vs-guidance timing divergence.
  2. Run the SUB-BIO-01 prompt (in ${CLAUDE_PLUGIN_ROOT}/skills/readout-handicap/references/prompts.md): trial design → phase-transition base rate → comparator → outcome distribution with probabilities → stock implications including "wins but disappoints" → positioning.
  3. Anchor probabilities in ${CLAUDE_PLUGIN_ROOT}/references/base-rates.md; adjust for indication-specific rates, endpoint quality (surrogate vs clinical, effect size vs powering, multiplicity), the Phase 2→3 translation gap (single-arm or small-N Phase 2s inflate expectations), and enrollment/timing signals. Show the PoS decomposition explicitly: technical × regulatory × commercial.
  4. Build the outcome distribution as mutually exclusive scenarios per the scenario discipline in ${CLAUDE_PLUGIN_ROOT}/references/evidence-translation-clinical.md — including clean win, statistical-win/clinical-shrug ("wins but disappoints"), mixed/subgroup, miss, and safety surprise — each with a probability and expected stock reaction vs what's implied.
  5. State the smart short's critique of the design (the criticisms a skeptic would raise) before concluding.
  6. End with the EVIDENCE BRIEF block (layer: clinical). Pass the PoS and scenario set to healthcare-equity model-valuation (MOD-03 rNPV) and portfolio (PORT-02 catalyst concentration).

© hh-health-AI, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

SKILL.md and 1 other file (references) in modules/clinical-catalysts/skills/readout-handicap of hh-health-AI/healthcare-equity.

  • SKILL.md
  • references/prompts.md

Open the folder on GitHubat commit 6c7bda8

Compare with similar skills

Readout Handicap next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Readout Handicap compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Readout Handicap this skillhh-health-AI/healthcare-equity101—~555Automated safety check: PassMIT
Icp Research Assistantirinabuht12-oss/marketing-skills4.1k—~1.8kAutomated safety check: PassNone
Bio Fragment AnalysisFreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repos~1.6kAutomated safety check: PassNone
Bio Clinical Biostatistics Missing DataGPTomics/bioSkills1.2k2 repos~8.4kAutomated safety check: PassMIT
Aerj Literature Positioningfranklee16/academic-research-skills2231 repos~774Automated safety check: PassNone
Ajs Literature Positioningfranklee16/academic-research-skills2231 repos~847Automated safety check: PassNone

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Questions about Readout Handicap

What does Readout Handicap do?

This skill should be used when the user says "handicap this readout", "pre-mortem the Phase 3", "what are the odds this trial works", "assess the trial design for [TICKER]", or before any binary…. Readout Handicap is an agent skill from hh-health-AI/healthcare-equity. This skill should be used when the user says "handicap this readout", "pre-mortem the Phase 3", "what are the odds this trial works", "assess the trial design for [TICKER]", or before any binary clinical data event where probability of success and outcome scenarios drive positioning.

When should I use Readout Handicap?

Readout Handicap fits situations like: says handicap this readout; pre-mortem the Phase 3; what are the odds this trial works; assess the trial design for [TICKER].

How do I install Readout Handicap in Claude Code?

Run `npx skills add hh-health-AI/healthcare-equity --skill readout-handicap -a claude-code`. Or copy the skill folder (modules/clinical-catalysts/skills/readout-handicap in hh-health-AI/healthcare-equity) into .claude/skills/readout-handicap in your project. Claude Code loads it when a task matches its description.

How do I install Readout Handicap in Codex?

Run `npx skills add hh-health-AI/healthcare-equity --skill readout-handicap -a codex`. Or copy the skill folder (modules/clinical-catalysts/skills/readout-handicap in hh-health-AI/healthcare-equity) into .agents/skills/readout-handicap in your project. Codex loads it when a task matches its description.

Can I use Readout Handicap in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add hh-health-AI/healthcare-equity --skill readout-handicap -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/readout-handicap, .gemini/skills/readout-handicap, .github/skills/readout-handicap and .opencode/skills/readout-handicap in your project.

What does Readout Handicap need to run?

SKILL.md names no scripts, command-line tools or credentials: Readout Handicap is instructions for the agent only.

Does Readout Handicap access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Readout Handicap safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Readout Handicap use?

Readout Handicap is published under the MIT licence (the repository's licence). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Readout Handicap use?

About 555 tokens (SKILL.md is roughly 2.2k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 212 tokens, read only when the agent opens those files.

What are the alternatives to Readout Handicap?

Skills that share tags, products or a category with Readout Handicap: Icp Research Assistant (irinabuht12-oss/marketing-skills, 4.1k stars), Bio Fragment Analysis (FreedomIntelligence/OpenClaw-Medical-Skills, 3.1k stars), Bio Clinical Biostatistics Missing Data (GPTomics/bioSkills, 1.2k stars) and Aerj Literature Positioning (franklee16/academic-research-skills, 223 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Readout Handicap?

hh-health-AI (a GitHub user) maintains it in hh-health-AI/healthcare-equity, which has 101 GitHub stars. The repository holds 72 skills in this directory. The repository was last updated on October 8, 2026.

Source: hh-health-AI/healthcare-equity on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.