Agent skill

Biosimilar Erosion

by hh-health-AI in hh-health-AI/healthcare-equity

This skill should be used when the user asks about "biosimilar erosion", "Purple Book", "biologic exclusivity", "interchangeability", "how fast will [biologic] erode", "erosion curve", or needs the…

MITAuto-check passedAI & LLM Engineering

Install Biosimilar Erosion

skills CLI
$ npx skills add hh-health-AI/healthcare-equity --skill biosimilar-erosion -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install hh-health-AI/healthcare-equity biosimilar-erosion --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/hh-health-AI/healthcare-equity.git skills-src && mkdir -p .claude/skills && cp -r skills-src/modules/ip-exclusivity/skills/biosimilar-erosion .claude/skills/biosimilar-erosion && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
biosimilar-erosion
GitHub stars
101
Token cost
~753 tokens
SKILL.md length
330 words
Files
2 (incl. references)
Skills in repo
72
Repo updated
First seen
Licence
MIT

At a glance

This skill should be used when the user asks about "biosimilar erosion", "Purple Book", "biologic exclusivity", "interchangeability", "how fast will [biologic] erode", "erosion curve", or needs the…

  • Works in 8 steps: Establish the reference product's… → Count and qualify the entrants. Not all… → Determine the substitution mechanism,… → …
  • Asks about biosimilar erosion
  • SKILL.md covers Workflow and Not-automatic
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Biosimilar Erosion is an agent skill from hh-health-AI/healthcare-equity. This skill should be used when the user asks about "biosimilar erosion", "Purple Book", "biologic exclusivity", "interchangeability", "how fast will [biologic] erode", "erosion curve", or needs the post-LOE revenue slope for a biologic. Anchors prompt-library ID SUB-PHA-05.

Its SKILL.md is about 750 tokens, which your agent loads only when the skill is triggered. The skill folder holds 2 other files, including reference files (for example `references/erosion-analogues.md`).

It sits in AI & LLM Engineering, covering Prompt engineering. The repository describes itself as: Synthesis engine for buy-side healthcare equity research. The licence is MIT.

When your agent uses it

  • Asks about biosimilar erosion
  • Biologic exclusivity
  • Interchangeability
  • How fast will [biologic] erode

Example prompts

  • “biosimilar erosion”
  • “Purple Book”
  • “biologic exclusivity”
  • “/biosimilar-erosion”

Workflow steps

8 steps, taken from the first numbered list in SKILL.md.

  1. Establish the reference product's position from the Purple Book
  2. Count and qualify the entrants. Not all approvals launch. Check for: launch
  3. Determine the substitution mechanism, which drives everything
  4. Model price and volume separately. Biosimilar competition is initially price-led
  5. Build the curve. Quarterly, from the entry date, with the shape justified by the
  6. Watch the defence. Reference-product sponsors deploy: authorised biosimilars,
  7. Instrument the curve. Once entry happens, replace assumption with observation
  8. Emit the brief.

What it can do on your machine

Read from SKILL.md and the folder at commit 6c7bda8. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md.

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Biosimilar Erosion loads about 753 tokens when it runs, and up to ~1.3k if it reads all its reference files. Until then it costs about 73 tokens; SKILL.md has 330 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~73
When it runs · the whole SKILL.md, loaded when a task matches
~753
With references · SKILL.md plus every file in references/, read only if the agent opens them
~1.3k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from hh-health-AI/healthcare-equity at commit 6c7bda8, republished under its MIT licence (© hh-health-AI). 330 words, ~753 tokens.

Download SKILL.mdSave it as .claude/skills/biosimilar-erosion/SKILL.md (or your agent's skills folder). This skill also uses 1 other file; get the full folder from GitHub.
name
biosimilar-erosion
description
This skill should be used when the user asks about "biosimilar erosion", "Purple Book", "biologic exclusivity", "interchangeability", "how fast will [biologic] erode", "erosion curve", or needs the post-LOE revenue slope for a biologic. Anchors prompt-library ID SUB-PHA-05.
metadata.version
0.1.0
metadata.layer
Competitive

Biosimilar erosion curve

Turn a biologic's exclusivity position and competitive set into a dated erosion curve that a revenue model can consume.

Workflow

  1. Establish the reference product's position from the Purple Book (scripts/purple_book.py): BLA number, first licensure date, reference-product exclusivity expiry, and any listed biosimilars with their licensure dates and interchangeability status.
  2. Count and qualify the entrants. Not all approvals launch. Check for: launch announcements, settlement-driven launch dates, manufacturing capacity, and whether the entrant is a large player with contracting muscle or a small one that will discount without winning share.
  3. Determine the substitution mechanism, which drives everything:
    • Interchangeable, pharmacy-dispensed → fastest erosion.
    • Not interchangeable, physician-administered, buy-and-bill → slowest; erosion depends on ASP dynamics and the physician's reimbursement spread, not on the pharmacy.
    • Payer-forced switching → step-shaped erosion at formulary dates (1 January is the usual step), not a smooth curve.
  4. Model price and volume separately. Biosimilar competition is initially price-led: the reference product often holds volume while conceding net price through rebates. A model that assumes volume loss will misread the first two years and then be surprised by the cliff when contracts finally flip.
  5. Build the curve. Quarterly, from the entry date, with the shape justified by the substitution mechanism and by two named analogue molecules with similar mechanics. Analogues do more work here than theory.
  6. Watch the defence. Reference-product sponsors deploy: authorised biosimilars, next-generation formulations (higher-concentration, subcutaneous, longer-acting), device improvements, and aggressive contracting that trades price for volume retention. Each changes the curve; name which ones are in play.
  7. Instrument the curve. Once entry happens, replace assumption with observation via rx-utilization → sdud-trx-proxy and Medicare Part B/D spending dashboards. A curve that is not being checked against data quarterly is a guess with a chart.
  8. Emit the brief.

Not-automatic

A biosimilar approval does not license an erosion assumption. Approval without launch, without interchangeability, or without contracting capacity produces very little erosion, and several approved biosimilars have never meaningfully launched.

Reference: references/erosion-analogues.md. Contract: ../../references/evidence-brief.md.

© hh-health-AI, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

SKILL.md and 1 other file (references) in modules/ip-exclusivity/skills/biosimilar-erosion of hh-health-AI/healthcare-equity.

  • SKILL.md
  • references/erosion-analogues.md

Open the folder on GitHubat commit 6c7bda8

Compare with similar skills

Biosimilar Erosion next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Biosimilar Erosion compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Biosimilar Erosion this skillhh-health-AI/healthcare-equity101—~753Automated safety check: PassMIT
Prompt Improverseverity1/claude-code-prompt-improver1.9k1 repos~1.7kAutomated safety check: PassMIT
Prompt Engineering Patternsynulihao/AgentSkillOS61814 repos~1.7kAutomated safety check: PassNone
Patch CreationPiebald-AI/tweakcc2.5k—~1.6kAutomated safety check: PassMIT
Senior Prompt Engineermaslennikov-ig/claude-code-orchestrator-kit2603 repos~1.4kAutomated safety check: PassCustom licence
Codex Fable5baskduf/FableCodex437—~1.6kAutomated safety check: PassAGPL-3.0

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Questions about Biosimilar Erosion

What does Biosimilar Erosion do?

This skill should be used when the user asks about "biosimilar erosion", "Purple Book", "biologic exclusivity", "interchangeability", "how fast will [biologic] erode", "erosion curve", or needs the…. Biosimilar Erosion is an agent skill from hh-health-AI/healthcare-equity. This skill should be used when the user asks about "biosimilar erosion", "Purple Book", "biologic exclusivity", "interchangeability", "how fast will [biologic] erode", "erosion curve", or needs the post-LOE revenue slope for a biologic.

When should I use Biosimilar Erosion?

Biosimilar Erosion fits situations like: asks about biosimilar erosion; biologic exclusivity; interchangeability; how fast will [biologic] erode.

How do I install Biosimilar Erosion in Claude Code?

Run `npx skills add hh-health-AI/healthcare-equity --skill biosimilar-erosion -a claude-code`. Or copy the skill folder (modules/ip-exclusivity/skills/biosimilar-erosion in hh-health-AI/healthcare-equity) into .claude/skills/biosimilar-erosion in your project. Claude Code loads it when a task matches its description.

How do I install Biosimilar Erosion in Codex?

Run `npx skills add hh-health-AI/healthcare-equity --skill biosimilar-erosion -a codex`. Or copy the skill folder (modules/ip-exclusivity/skills/biosimilar-erosion in hh-health-AI/healthcare-equity) into .agents/skills/biosimilar-erosion in your project. Codex loads it when a task matches its description.

Can I use Biosimilar Erosion in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add hh-health-AI/healthcare-equity --skill biosimilar-erosion -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/biosimilar-erosion, .gemini/skills/biosimilar-erosion, .github/skills/biosimilar-erosion and .opencode/skills/biosimilar-erosion in your project.

What does Biosimilar Erosion need to run?

SKILL.md names no scripts, command-line tools or credentials: Biosimilar Erosion is instructions for the agent only.

Does Biosimilar Erosion access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Biosimilar Erosion safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Biosimilar Erosion use?

Biosimilar Erosion is published under the MIT licence (the repository's licence). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Biosimilar Erosion use?

About 753 tokens (SKILL.md is roughly 3k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 505 tokens, read only when the agent opens those files.

What are the alternatives to Biosimilar Erosion?

Skills that share tags, products or a category with Biosimilar Erosion: Prompt Improver (severity1/claude-code-prompt-improver, 1.9k stars), Prompt Engineering Patterns (ynulihao/AgentSkillOS, 618 stars), Patch Creation (Piebald-AI/tweakcc, 2.5k stars) and Senior Prompt Engineer (maslennikov-ig/claude-code-orchestrator-kit, 260 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Biosimilar Erosion?

hh-health-AI (a GitHub user) maintains it in hh-health-AI/healthcare-equity, which has 101 GitHub stars. The repository holds 72 skills in this directory. The repository was last updated on October 8, 2026.

Source: hh-health-AI/healthcare-equity on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.