Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin.

No licenceAuto-check passedMarketing & SEO

Install Bio Fragment Analysis

skills CLI
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-fragment-analysis -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-fragment-analysis --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bio-fragment-analysis .claude/skills/bio-fragment-analysis && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
bio-fragment-analysis
GitHub stars
3.1k
Used in
1 other repo
Token cost
~1.6k tokens
SKILL.md length
248 words
Files
3
Skills in repo
279
Repo updated
First seen
Licence
None found

At a glance

Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin.

  • Leveraging fragment patterns for tumor detection
  • SKILL.md covers Version Compatibility, Tool Selection, Fragment Size Metrics and FinaleToolkit Analysis, plus 4 more sections
  • Runs Python scripts from its folder; calls pip
  • Tissue-of-origin analysis

What it does

Bio Fragment Analysis is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin. Extracts nucleosome positioning patterns, fragment ratios, and DELFI-style fragmentation profiles for cancer detection. Use when leveraging fragment patterns for tumor detection or tissue-of-origin analysis.

Its SKILL.md is about 1.6k tokens, which your agent loads only when the skill is triggered. The skill folder holds 3 other files (for example `examples/fragment_analysis.py` and `usage-guide.md`).

It sits in Marketing & SEO, covering Positioning and messaging. It works with Python. The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.

When your agent uses it

  • Leveraging fragment patterns for tumor detection
  • Tissue-of-origin analysis

Example prompts

  • “Use the bio-fragment-analysis skill to analyz cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin”
  • “/bio-fragment-analysis”

Requirements

  • Python 3

What it can do on your machine

Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships script files (Python), which the agent can run.

    Shell commands in SKILL.md call:

    • pip

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md. Its commands use pip, which can reach the network depending on how they are called.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Bio Fragment Analysis loads about 1.6k tokens when it runs. Until then it costs about 83 tokens; SKILL.md has 248 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~83
When it runs · the whole SKILL.md, loaded when a task matches
~1.6k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 248 words (~1,632 tokens).

“Reference examples tested with: numpy 1.26+, pandas 2.2+, pysam 0.22+”

— opening of SKILL.md by FreedomIntelligence
name
bio-fragment-analysis
tool_type
python
primary_tool
FinaleToolkit

Read the full SKILL.md on GitHub

Files

SKILL.md and 2 other files in skills/bio-fragment-analysis of FreedomIntelligence/OpenClaw-Medical-Skills.

  • SKILL.md
  • examples/fragment_analysis.py
  • usage-guide.md

Open the folder on GitHubat commit b1f9b6e

Used in 1 other repository

We found 2 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in FreedomIntelligence/OpenClaw-Medical-Skills, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Bio Fragment Analysis next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Bio Fragment Analysis compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Bio Fragment Analysis this skillFreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repos~1.6kAutomated safety check: PassNone
Releasechrisguidry/docket149—~1.4kAutomated safety check: PassCustom licence
Yao Positioning Skillyaojingang/yao-open-skills1.3k—~805Automated safety check: PassMIT
Bio Atac Seq Nucleosome PositioningGPTomics/bioSkills1.2k2 repos~4.9kAutomated safety check: PassMIT
Geo Site Diagnoseyaojingang/GEOHub165—~515Automated safety check: PassAGPL-3.0
Icp Research Assistantirinabuht12-oss/marketing-skills4k—~1.8kAutomated safety check: PassNone

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  • Map nucleosome center positions, occupancy, and fuzziness from ATAC-seq fragment-size patterns using NucleoATAC, ATACseqQC, DANPOS3, or scprinter.

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Works with

Questions about Bio Fragment Analysis

What does Bio Fragment Analysis do?

Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin. Bio Fragment Analysis is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin.

When should I use Bio Fragment Analysis?

Bio Fragment Analysis fits situations like: leveraging fragment patterns for tumor detection; tissue-of-origin analysis.

How do I install Bio Fragment Analysis in Claude Code?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-fragment-analysis -a claude-code`. Or copy the skill folder (skills/bio-fragment-analysis in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/bio-fragment-analysis in your project. Claude Code loads it when a task matches its description.

How do I install Bio Fragment Analysis in Codex?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-fragment-analysis -a codex`. Or copy the skill folder (skills/bio-fragment-analysis in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/bio-fragment-analysis in your project. Codex loads it when a task matches its description.

Can I use Bio Fragment Analysis in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-fragment-analysis -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bio-fragment-analysis, .gemini/skills/bio-fragment-analysis, .github/skills/bio-fragment-analysis and .opencode/skills/bio-fragment-analysis in your project.

What does Bio Fragment Analysis need to run?

Going by SKILL.md and its folder, Bio Fragment Analysis needs Python for the scripts in its folder and the command-line tools its instructions call (pip). Our summary lists: Python 3.

Does Bio Fragment Analysis access the network?

SKILL.md contains no URLs. Its commands use pip, which can reach the network depending on how they are called. This is read from the text; nothing was executed.

Is Bio Fragment Analysis safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Bio Fragment Analysis use?

No licence was found for Bio Fragment Analysis or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Bio Fragment Analysis use?

About 1.6k tokens (SKILL.md is roughly 6.5k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Bio Fragment Analysis?

Skills that share tags, products or a category with Bio Fragment Analysis: Release (chrisguidry/docket, 149 stars), Yao Positioning Skill (yaojingang/yao-open-skills, 1.3k stars), Bio Atac Seq Nucleosome Positioning (GPTomics/bioSkills, 1.2k stars) and Geo Site Diagnose (yaojingang/GEOHub, 165 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Bio Fragment Analysis?

FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,052 GitHub stars. The repository holds 279 skills in this directory. The repository was last updated on July 21, 2026.

Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.