Agent skill

Protein Interaction Network Analysis

by FreedomIntelligence in FreedomIntelligence/OpenClaw-Medical-Skills

Analyze protein-protein interaction networks using STRING, BioGRID, and SASBDB databases.

No licenceAuto-check: notes

Install Protein Interaction Network Analysis

skills CLI
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill protein-interaction-network-analysis -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills protein-interaction-network-analysis --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/tooluniverse-protein-interactions .claude/skills/protein-interaction-network-analysis && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
protein-interaction-network-analysis
GitHub stars
3.1k
Used in
2 other repos
Token cost
~3.7k tokens
SKILL.md length
667 words
Files
15
Skills in repo
170
Repo updated
First seen
Licence
None found

At a glance

Analyze protein-protein interaction networks using STRING, BioGRID, and SASBDB databases.

  • Works in 9 steps: Single Protein Analysis → Protein Complex Validation → Pathway Discovery → …
  • Analyzing protein networks
  • SKILL.md covers Features, Databases Used, Quick Start and Use Cases, plus 5 more sections
  • Runs Python scripts from its folder; calls pip and python; needs BIOGRID_API_KEY

What it does

Protein Interaction Network Analysis is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Analyze protein-protein interaction networks using STRING, BioGRID, and SASBDB databases. Maps protein identifiers, retrieves interaction networks with confidence scores, performs functional enrichment analysis (GO/KEGG/Reactome), and optionally includes structural data. No API key required for core functionality (STRING). Use when analyzing protein networks, discovering interaction partners, identifying functional modules, or studying protein complexes.

Its SKILL.md is about 3.7k tokens, which your agent loads only when the skill is triggered. The skill folder holds 14 other files (for example `DESCRIPTION_UPDATE_COMPLETE.md`, `DESCRIPTION_UPDATE_PROGRESS.md` and `DOMAIN_ANALYSIS.md`).

The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.

When your agent uses it

  • Analyzing protein networks
  • Discovering interaction partners
  • Identifying functional modules
  • Studying protein complexes

Example prompts

  • “/protein-interaction-network-analysis”

Requirements

  • Python 3
  • A credential in BIOGRID_API_KEY

Workflow steps

9 steps, taken from the step headings in SKILL.md.

  1. Single Protein Analysis
  2. Protein Complex Validation
  3. Pathway Discovery
  4. Multi-Protein Network Analysis
  5. With BioGRID Validation
  6. Including Structural Data
  7. ToolUniverse Verbose Output
  8. BioGRID Requires API Key
  9. SASBDB May Have API Issues

What it can do on your machine

Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships script files (Python), which the agent can run.

    Shell commands in SKILL.md call:

    • pip
    • python

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    Links to these hosts (documentation or services it may open):

    • webservice.thebiogrid.org
    • string-db.org
    • thebiogrid.org
    • sasbdb.org
    • github.com

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names these keys or tokens, usually read from environment variables:

    • BIOGRID_API_KEY

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Protein Interaction Network Analysis loads about 3.7k tokens when it runs. Until then it costs about 124 tokens; SKILL.md has 667 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~124
When it runs · the whole SKILL.md, loaded when a task matches
~3.7k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check: notes

The automated check noted patterns worth knowing about, such as sudo or a known installer.

  • NoteMentions a .env fileSKILL.md:339
    2. Add to `.env` file:

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 667 words (~3,741 tokens).

“Comprehensive protein interaction network analysis using ToolUniverse tools. Analyzes protein networks through a 4-phase workflow: identifier mapping, network retrieval, enrichment analysis, and optional structural data.”

— opening of SKILL.md by FreedomIntelligence
name
protein-interaction-network-analysis

Read the full SKILL.md on GitHub

Files

SKILL.md and 14 other files in skills/tooluniverse-protein-interactions of FreedomIntelligence/OpenClaw-Medical-Skills.

  • SKILL.md
  • .env.template
  • DESCRIPTION_UPDATE_COMPLETE.md
  • DESCRIPTION_UPDATE_PROGRESS.md
  • DOMAIN_ANALYSIS.md
  • KNOWN_ISSUES.md
  • PHASE2_COMPLETE.md
  • PHASE2_DISCOVERIES.md
  • PHASE4_IMPLEMENTATION_COMPLETE.md
  • PHASE5_DOCUMENTATION_COMPLETE.md
  • QUICK_START.md
  • TOOL_DESCRIPTION_OPTIMIZATION.md
  • python_implementation.py
  • test_protein_tools.py
  • test_skill_comprehensive.py

Open the folder on GitHubat commit b1f9b6e

Used in 2 other repositories

We found 2 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 2 other GitHub owners. This page covers the copy in FreedomIntelligence/OpenClaw-Medical-Skills, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Protein Interaction Network Analysis next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Protein Interaction Network Analysis compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Protein Interaction Network Analysis this skillFreedomIntelligence/OpenClaw-Medical-Skills3.1k2 repos~3.7kAutomated safety check: NotesNone
String Protein Interaction Analysis With Omicversemajiayu000/claude-skill-registry6662 repos~749Automated safety check: PassMIT
String Databasedavila7/claude-code-templates32k11 repos~4.5kAutomated safety check: PassMIT
Linux NetworkingRightNow-AI/openfang18k—~882Automated safety check: PassApache-2.0
Performing Ot Network Security Assessmentmukul975/Anthropic-Cybersecurity-Skills34k—~6.1kAutomated safety check: PassApache-2.0
String Databaseaipoch/medical-research-skills2k—~928Automated safety check: PassMIT

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Questions about Protein Interaction Network Analysis

What does Protein Interaction Network Analysis do?

Analyze protein-protein interaction networks using STRING, BioGRID, and SASBDB databases. Protein Interaction Network Analysis is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Analyze protein-protein interaction networks using STRING, BioGRID, and SASBDB databases.

When should I use Protein Interaction Network Analysis?

Protein Interaction Network Analysis fits situations like: analyzing protein networks; discovering interaction partners; identifying functional modules; studying protein complexes.

How do I install Protein Interaction Network Analysis in Claude Code?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill protein-interaction-network-analysis -a claude-code`. Or copy the skill folder (skills/tooluniverse-protein-interactions in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/protein-interaction-network-analysis in your project. Claude Code loads it when a task matches its description.

How do I install Protein Interaction Network Analysis in Codex?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill protein-interaction-network-analysis -a codex`. Or copy the skill folder (skills/tooluniverse-protein-interactions in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/protein-interaction-network-analysis in your project. Codex loads it when a task matches its description.

Can I use Protein Interaction Network Analysis in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill protein-interaction-network-analysis -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/protein-interaction-network-analysis, .gemini/skills/protein-interaction-network-analysis, .github/skills/protein-interaction-network-analysis and .opencode/skills/protein-interaction-network-analysis in your project.

What does Protein Interaction Network Analysis need to run?

Going by SKILL.md and its folder, Protein Interaction Network Analysis needs Python for the scripts in its folder, the command-line tools its instructions call (pip and python) and credentials named BIOGRID_API_KEY. Our summary lists: Python 3; A credential in BIOGRID_API_KEY.

Does Protein Interaction Network Analysis access the network?

SKILL.md names 5 domains. As links in the text: webservice.thebiogrid.org, string-db.org, thebiogrid.org, sasbdb.org and github.com. This is read from the text; nothing was executed.

Is Protein Interaction Network Analysis safe to install?

Our automated static check of SKILL.md found notes only (mentions a .env file), nothing it rates as a warning. It is not a guarantee. Review the folder before installing.

What licence does Protein Interaction Network Analysis use?

No licence was found for Protein Interaction Network Analysis or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Protein Interaction Network Analysis use?

About 3.7k tokens (SKILL.md is roughly 15k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Protein Interaction Network Analysis?

Skills that share tags, products or a category with Protein Interaction Network Analysis: String Protein Interaction Analysis With Omicverse (majiayu000/claude-skill-registry, 666 stars), String Database (davila7/claude-code-templates, 32k stars), Linux Networking (RightNow-AI/openfang, 18k stars) and Performing Ot Network Security Assessment (mukul975/Anthropic-Cybersecurity-Skills, 34k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Protein Interaction Network Analysis?

FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,052 GitHub stars. The repository holds 170 skills in this directory. The repository was last updated on July 21, 2026.

Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.