Agent skill

String Database

by aipoch in aipoch/medical-research-skills

Access the STRING database to map identifiers, retrieve protein–protein interaction networks, and run functional/PPI enrichment when you need interaction context for a gene/protein set.

MITAuto-check passedResearch & Science

Install String Database

skills CLI
$ npx skills add aipoch/medical-research-skills --skill string-database -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install aipoch/medical-research-skills string-database --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/aipoch/medical-research-skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/'scientific-skills/Evidence Insight/string-database' .claude/skills/string-database && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
string-database
GitHub stars
2k
Token cost
~928 tokens
SKILL.md length
300 words
Files
5 (incl. scripts, references)
Skills in repo
567
Repo updated
First seen
Licence
MIT

At a glance

Access the STRING database to map identifiers, retrieve protein–protein interaction networks, and run functional/PPI enrichment when you need interaction context for a gene/protein set.

  • Research & Science work in your project
  • SKILL.md covers When to Use, Key Features, Dependencies and Example Usage, plus 1 more section
  • Runs Python scripts from its folder; calls pip

What it does

String Database is an agent skill from aipoch/medical-research-skills. Access the STRING database to map identifiers, retrieve protein–protein interaction networks, and run functional/PPI enrichment when you need interaction context for a gene/protein set.

Its SKILL.md is about 930 tokens, which your agent loads only when the skill is triggered. The skill folder holds 6 other files, including scripts and reference files (for example `references/string_reference.md`, `scripts/__init__.py` and `scripts/string_api.py`).

It sits in Research & Science. The repository describes itself as: Hundreds of agent skills for medical research, including protocol design, data analysis, evidence insights, and academic writing. The licence is MIT.

When your agent uses it

  • Research & Science work in your project

Example prompts

  • “/string-database”

Requirements

  • Python 3

What it can do on your machine

Read from SKILL.md and the folder at commit 686e09d. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships 2 files in scripts/ (Python), which the agent can run.

    Shell commands in SKILL.md call:

    • pip

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md. Its commands use pip, which can reach the network depending on how they are called.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

String Database loads about 928 tokens when it runs, and up to ~1.3k if it reads all its reference files. Until then it costs about 50 tokens; SKILL.md has 300 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~50
When it runs · the whole SKILL.md, loaded when a task matches
~928
With references · SKILL.md plus every file in references/, read only if the agent opens them
~1.3k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); the scripts in this folder are not scanned.

SKILL.md

The full file from aipoch/medical-research-skills at commit 686e09d, republished under its MIT licence (© aipoch). 300 words, ~928 tokens.

Download SKILL.mdSave it as .claude/skills/string-database/SKILL.md (or your agent's skills folder). This skill also uses 4 other files; get the full folder from GitHub.
name
string-database
description
Access the STRING database to map identifiers, retrieve protein–protein interaction networks, and run functional/PPI enrichment when you need interaction context for a gene/protein set.
license
MIT
author
AIPOCH

Source: https://github.com/aipoch/medical-research-skills

When to Use

  • You have gene symbols (e.g., TP53) and need to resolve them to STRING protein identifiers for downstream analysis.
  • You want to retrieve a protein–protein interaction (PPI) network (functional/physical) with confidence scores for one or more proteins.
  • You need to find interaction partners for a target protein to expand a candidate list (e.g., add top N neighbors).
  • You want to perform functional enrichment (GO/KEGG/Reactome, etc.) for a protein set to interpret biological themes.
  • You need a quick static visualization (PNG/SVG) of a STRING network for reports or notebooks.

Key Features

  • ID Mapping: Convert gene/protein names to STRING identifiers for a given organism.
  • Network Retrieval: Fetch interaction edges with confidence scores from STRING.
  • Interaction Partners: Expand a protein list by retrieving interaction partners.
  • Enrichment Analysis:
    • Functional enrichment (e.g., GO, KEGG, Reactome)
    • PPI enrichment statistics
    • Functional annotations (e.g., PFAM/SMART where supported by STRING endpoints)
  • Visualization: Download static network images (PNG/SVG).

Dependencies

  • Python >=3.8
  • requests (tested with >=2.28)
  • pandas (tested with >=1.5)

Install:

bash
pip install requests pandas

Example Usage

python
from scripts.string_api import StringClient

def main():
    # STRING does not require a secret API key, but providing a caller identity is recommended.
    client = StringClient(caller_identity="my_analysis_tool")

    # 1) Map an identifier (e.g., TP53 in Homo sapiens; NCBI taxonomy ID 9606)
    protein_id = client.map_id(identifier="TP53", species=9606)
    print("Mapped ID:", protein_id)

    # 2) Download a network image and expand by adding interaction partners
    client.get_network_image(
        identifiers=[protein_id],
        output_file="tp53_network.png",
        add_color_nodes=10,  # add 10 partners
    )
    print("Saved network image to tp53_network.png")

    # 3) Run PPI enrichment for the set
    ppi_stats = client.get_ppi_enrichment(identifiers=[protein_id])
    print("PPI enrichment:", ppi_stats)

if __name__ == "__main__":
    main()

Implementation Details

  • Client entry point: scripts/string_api.py provides the main wrapper (e.g., StringClient) around the STRING REST API.
  • Caller identity:
    • STRING endpoints do not require an API key.
    • A caller_identity string is strongly recommended (project name/email/URL) to support rate/load management.
    • Pass it at initialization (e.g., StringClient(caller_identity="my_email@example.com")) or inject via environment variables in your own wrapper.
  • Organism selection:
    • Most operations require a species identifier (commonly NCBI taxonomy ID, e.g., 9606 for human).
  • Network retrieval and scoring:
    • Network endpoints return interactions with confidence scores; downstream filtering is typically done by applying a score threshold in your analysis code (if exposed by the wrapper).
  • Visualization:
    • Static images are retrieved directly from STRING image endpoints and written to disk (PNG/SVG depending on the method/parameters).
  • Reference documentation:
    • See references/string_reference.md for original API notes and endpoint details included with this skill.

© aipoch, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

SKILL.md and 4 other files (scripts, references) in scientific-skills/Evidence Insight/string-database of aipoch/medical-research-skills.

  • SKILL.md
  • references/string_reference.md
  • scripts/__init__.py
  • scripts/string_api.py
  • string-database_audit_result_v1.json

Open the folder on GitHubat commit 686e09d

Compare with similar skills

String Database next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

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GitHub Deep Researchbytedance/deer-flow83k5 repos~1.3kAutomated safety check: PassMIT
Nature Paper CardYuan1z0825/nature-skills46k2 repos~2.1kAutomated safety check: PassApache-2.0
Read arXiv Paperkarpathy/nanochat58k2 repos~494Automated safety check: PassMIT
Content Research Writerweapp-tailwindcss/weapp-tailwindcss1.9k25 repos~3.5kAutomated safety check: PassMIT

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Questions about String Database

What does String Database do?

Access the STRING database to map identifiers, retrieve protein–protein interaction networks, and run functional/PPI enrichment when you need interaction context for a gene/protein set. String Database is an agent skill from aipoch/medical-research-skills. Access the STRING database to map identifiers, retrieve protein–protein interaction networks, and run functional/PPI enrichment when you need interaction context for a gene/protein set.

When should I use String Database?

String Database fits situations like: research & Science work in your project.

How do I install String Database in Claude Code?

Run `npx skills add aipoch/medical-research-skills --skill string-database -a claude-code`. Or copy the skill folder (scientific-skills/Evidence Insight/string-database in aipoch/medical-research-skills) into .claude/skills/string-database in your project. Claude Code loads it when a task matches its description.

How do I install String Database in Codex?

Run `npx skills add aipoch/medical-research-skills --skill string-database -a codex`. Or copy the skill folder (scientific-skills/Evidence Insight/string-database in aipoch/medical-research-skills) into .agents/skills/string-database in your project. Codex loads it when a task matches its description.

Can I use String Database in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add aipoch/medical-research-skills --skill string-database -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/string-database, .gemini/skills/string-database, .github/skills/string-database and .opencode/skills/string-database in your project.

What does String Database need to run?

Going by SKILL.md and its folder, String Database needs Python for the scripts in its folder and the command-line tools its instructions call (pip). Our summary lists: Python 3.

Does String Database access the network?

SKILL.md contains no URLs. Its commands use pip, which can reach the network depending on how they are called. This is read from the text; nothing was executed.

Is String Database safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. The check reads SKILL.md only: the scripts in the folder are not scanned, so read them before running anything.

What licence does String Database use?

String Database is published under the MIT licence (declared in SKILL.md). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does String Database use?

About 928 tokens (SKILL.md is roughly 3.7k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 358 tokens, read only when the agent opens those files.

What are the alternatives to String Database?

Skills that share tags, products or a category with String Database: Hypothesis Generation (spacering-net/codeg, 3.8k stars), GitHub Deep Research (bytedance/deer-flow, 83k stars), Nature Paper Card (Yuan1z0825/nature-skills, 46k stars) and Read arXiv Paper (karpathy/nanochat, 58k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains String Database?

aipoch (a GitHub organization) maintains it in aipoch/medical-research-skills, which has 1,974 GitHub stars. The repository holds 567 skills in this directory. The repository was last updated on September 17, 2026.

Source: aipoch/medical-research-skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.