Agent skill

Bio Hi C Analysis Hic Differential

by FreedomIntelligence in FreedomIntelligence/OpenClaw-Medical-Skills

Compare Hi-C contact matrices between conditions to identify differential chromatin interactions.

No licenceAuto-check passedMarketing & SEO

Install Bio Hi C Analysis Hic Differential

skills CLI
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-hi-c-analysis-hic-differential -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-hi-c-analysis-hic-differential --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bio-hi-c-analysis-hic-differential .claude/skills/bio-hi-c-analysis-hic-differential && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
bio-hi-c-analysis-hic-differential
GitHub stars
3.1k
Used in
1 other repo
Token cost
~2.6k tokens
SKILL.md length
209 words
Files
3
Skills in repo
279
Repo updated
First seen
Licence
None found

At a glance

Compare Hi-C contact matrices between conditions to identify differential chromatin interactions.

  • Comparing Hi-C contacts between conditions
  • SKILL.md covers Version Compatibility, Required Imports, Load Two Conditions and Compute Log2 Fold Change, plus 11 more sections
  • Runs Python scripts from its folder; calls pip
  • Tasks that involve A/B testing

What it does

Bio Hi C Analysis Hic Differential is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Compare Hi-C contact matrices between conditions to identify differential chromatin interactions. Compute log2 fold changes, statistical significance, and visualize differential contact maps. Use when comparing Hi-C contacts between conditions.

Its SKILL.md is about 2.6k tokens, which your agent loads only when the skill is triggered. The skill folder holds 3 other files (for example `examples/compare_hic.py` and `usage-guide.md`).

It sits in Marketing & SEO, covering A/B testing. The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.

When your agent uses it

  • Comparing Hi-C contacts between conditions
  • Tasks that involve A/B testing

Example prompts

  • “/bio-hi-c-analysis-hic-differential”

Requirements

  • Python 3

What it can do on your machine

Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships script files (Python), which the agent can run.

    Shell commands in SKILL.md call:

    • pip

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md. Its commands use pip, which can reach the network depending on how they are called.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Bio Hi C Analysis Hic Differential loads about 2.6k tokens when it runs. Until then it costs about 70 tokens; SKILL.md has 209 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~70
When it runs · the whole SKILL.md, loaded when a task matches
~2.6k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 209 words (~2,650 tokens).

“Reference examples tested with: cooler 0.9+, cooltools 0.6+, matplotlib 3.8+, numpy 1.26+, pandas 2.2+, scipy 1.12+, statsmodels 0.14+”

— opening of SKILL.md by FreedomIntelligence
name
bio-hi-c-analysis-hic-differential
tool_type
python
primary_tool
cooltools

Read the full SKILL.md on GitHub

Files

SKILL.md and 2 other files in skills/bio-hi-c-analysis-hic-differential of FreedomIntelligence/OpenClaw-Medical-Skills.

  • SKILL.md
  • examples/compare_hic.py
  • usage-guide.md

Open the folder on GitHubat commit b1f9b6e

Used in 1 other repository

We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in FreedomIntelligence/OpenClaw-Medical-Skills, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Bio Hi C Analysis Hic Differential next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Bio Hi C Analysis Hic Differential compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Bio Hi C Analysis Hic Differential this skillFreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repos~2.6kAutomated safety check: PassNone
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App Analyticsappeeky/aso-skills2.2k—~1.6kAutomated safety check: PassMIT
Ab Test Analysisnimrodfisher/data-analytics-skills470—~708Automated safety check: PassMIT
Ab Testingericrisco/rsc-harness180—~2.4kAutomated safety check: PassMIT
Measure Experiment Resultsproduct-on-purpose/pm-skills716—~989Automated safety check: PassApache-2.0

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Questions about Bio Hi C Analysis Hic Differential

What does Bio Hi C Analysis Hic Differential do?

Compare Hi-C contact matrices between conditions to identify differential chromatin interactions. Bio Hi C Analysis Hic Differential is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Compare Hi-C contact matrices between conditions to identify differential chromatin interactions.

When should I use Bio Hi C Analysis Hic Differential?

Bio Hi C Analysis Hic Differential fits situations like: comparing Hi-C contacts between conditions; tasks that involve A/B testing.

How do I install Bio Hi C Analysis Hic Differential in Claude Code?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-hi-c-analysis-hic-differential -a claude-code`. Or copy the skill folder (skills/bio-hi-c-analysis-hic-differential in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/bio-hi-c-analysis-hic-differential in your project. Claude Code loads it when a task matches its description.

How do I install Bio Hi C Analysis Hic Differential in Codex?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-hi-c-analysis-hic-differential -a codex`. Or copy the skill folder (skills/bio-hi-c-analysis-hic-differential in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/bio-hi-c-analysis-hic-differential in your project. Codex loads it when a task matches its description.

Can I use Bio Hi C Analysis Hic Differential in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-hi-c-analysis-hic-differential -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bio-hi-c-analysis-hic-differential, .gemini/skills/bio-hi-c-analysis-hic-differential, .github/skills/bio-hi-c-analysis-hic-differential and .opencode/skills/bio-hi-c-analysis-hic-differential in your project.

What does Bio Hi C Analysis Hic Differential need to run?

Going by SKILL.md and its folder, Bio Hi C Analysis Hic Differential needs Python for the scripts in its folder and the command-line tools its instructions call (pip). Our summary lists: Python 3.

Does Bio Hi C Analysis Hic Differential access the network?

SKILL.md contains no URLs. Its commands use pip, which can reach the network depending on how they are called. This is read from the text; nothing was executed.

Is Bio Hi C Analysis Hic Differential safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Bio Hi C Analysis Hic Differential use?

No licence was found for Bio Hi C Analysis Hic Differential or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Bio Hi C Analysis Hic Differential use?

About 2.6k tokens (SKILL.md is roughly 11k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Bio Hi C Analysis Hic Differential?

Skills that share tags, products or a category with Bio Hi C Analysis Hic Differential: Analytics (Nexus-JPF/note-companion, 870 stars), App Analytics (appeeky/aso-skills, 2.2k stars), Ab Test Analysis (nimrodfisher/data-analytics-skills, 470 stars) and Ab Testing (ericrisco/rsc-harness, 180 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Bio Hi C Analysis Hic Differential?

FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,053 GitHub stars. The repository holds 279 skills in this directory. The repository was last updated on July 21, 2026.

Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.