ChIP-seq quality control metrics including FRiP (Fraction of Reads in Peaks), cross-correlation analysis (NSC/RSC), library complexity, and IDR (Irreproducibility Discovery Rate) for replicate…

No licenceAuto-check passedData & Analytics

Install Bio Chipseq Qc

skills CLI
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-qc -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-chipseq-qc --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bio-chipseq-qc .claude/skills/bio-chipseq-qc && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
bio-chipseq-qc
GitHub stars
3.1k
Token cost
~2.7k tokens
SKILL.md length
494 words
Files
5
Skills in repo
279
Repo updated
First seen
Licence
None found

At a glance

ChIP-seq quality control metrics including FRiP (Fraction of Reads in Peaks), cross-correlation analysis (NSC/RSC), library complexity, and IDR (Irreproducibility Discovery Rate) for replicate…

  • Assess experiment quality before downstream analysis
  • SKILL.md covers Version Compatibility, FRiP (Fraction of Reads in…, Cross-Correlation Analysis… and Library Complexity (NRF, PBC1,…, plus 5 more sections
  • Runs Shell and Python scripts from its folder; calls pip
  • Assessing ChIP-seq data quality metrics

What it does

Bio Chipseq Qc is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. ChIP-seq quality control metrics including FRiP (Fraction of Reads in Peaks), cross-correlation analysis (NSC/RSC), library complexity, and IDR (Irreproducibility Discovery Rate) for replicate concordance. Use to assess experiment quality before downstream analysis. Use when assessing ChIP-seq data quality metrics.

Its SKILL.md is about 2.7k tokens, which your agent loads only when the skill is triggered. The skill folder holds 5 other files (for example `examples/calculate_frip.sh`, `examples/chipseq_qc.py` and `examples/run_idr.sh`).

It sits in Data & Analytics, covering Bioinformatics and Data cleaning. It works with pysam. The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.

When your agent uses it

  • Assess experiment quality before downstream analysis
  • Assessing ChIP-seq data quality metrics

Example prompts

  • “/bio-chipseq-qc”

Requirements

  • Python 3
  • A Bash shell

What it can do on your machine

Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships script files (Shell and Python), which the agent can run.

    Shell commands in SKILL.md call:

    • pip

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md. Its commands use pip, which can reach the network depending on how they are called.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Bio Chipseq Qc loads about 2.7k tokens when it runs. Until then it costs about 83 tokens; SKILL.md has 494 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~83
When it runs · the whole SKILL.md, loaded when a task matches
~2.7k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 494 words (~2,740 tokens).

“Reference examples tested with: MACS3 3.0+, Subread 2.0+, bedtools 2.31+, deepTools 3.5+, pybedtools 0.9+, pysam 0.22+, samtools 1.19+”

— opening of SKILL.md by FreedomIntelligence
name
bio-chipseq-qc
tool_type
mixed
primary_tool
deepTools

Read the full SKILL.md on GitHub

Files

SKILL.md and 4 other files in skills/bio-chipseq-qc of FreedomIntelligence/OpenClaw-Medical-Skills.

  • SKILL.md
  • examples/calculate_frip.sh
  • examples/chipseq_qc.py
  • examples/run_idr.sh
  • usage-guide.md

Open the folder on GitHubat commit b1f9b6e

Compare with similar skills

Bio Chipseq Qc next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Bio Chipseq Qc compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Bio Chipseq Qc this skillFreedomIntelligence/OpenClaw-Medical-Skills3.1k—~2.7kAutomated safety check: PassNone
Bio Batch ProcessingGPTomics/bioSkills1.2k1 repos~3kAutomated safety check: PassMIT
Bio Workflows Methylation PipelineGPTomics/bioSkills1.2k1 repos~3.7kAutomated safety check: PassMIT
Bio Proteomics Differential AbundanceGPTomics/bioSkills1.2k1 repos~5.7kAutomated safety check: PassMIT
Bioconductor HarmonizrbioMate-AI/biomate-bioconductor-kb804—~1.2kAutomated safety check: PassCustom licence
Bio Alignment ValidationGPTomics/bioSkills1.2k2 repos~3.7kAutomated safety check: PassMIT

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Works with

Questions about Bio Chipseq Qc

What does Bio Chipseq Qc do?

ChIP-seq quality control metrics including FRiP (Fraction of Reads in Peaks), cross-correlation analysis (NSC/RSC), library complexity, and IDR (Irreproducibility Discovery Rate) for replicate…. Bio Chipseq Qc is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. ChIP-seq quality control metrics including FRiP (Fraction of Reads in Peaks), cross-correlation analysis (NSC/RSC), library complexity, and IDR (Irreproducibility Discovery Rate) for replicate concordance.

When should I use Bio Chipseq Qc?

Bio Chipseq Qc fits situations like: assess experiment quality before downstream analysis; assessing ChIP-seq data quality metrics.

How do I install Bio Chipseq Qc in Claude Code?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-qc -a claude-code`. Or copy the skill folder (skills/bio-chipseq-qc in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/bio-chipseq-qc in your project. Claude Code loads it when a task matches its description.

How do I install Bio Chipseq Qc in Codex?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-qc -a codex`. Or copy the skill folder (skills/bio-chipseq-qc in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/bio-chipseq-qc in your project. Codex loads it when a task matches its description.

Can I use Bio Chipseq Qc in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-qc -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bio-chipseq-qc, .gemini/skills/bio-chipseq-qc, .github/skills/bio-chipseq-qc and .opencode/skills/bio-chipseq-qc in your project.

What does Bio Chipseq Qc need to run?

Going by SKILL.md and its folder, Bio Chipseq Qc needs a shell and Python for the scripts in its folder and the command-line tools its instructions call (pip). Our summary lists: Python 3; A Bash shell.

Does Bio Chipseq Qc access the network?

SKILL.md contains no URLs. Its commands use pip, which can reach the network depending on how they are called. This is read from the text; nothing was executed.

Is Bio Chipseq Qc safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Bio Chipseq Qc use?

No licence was found for Bio Chipseq Qc or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Bio Chipseq Qc use?

About 2.7k tokens (SKILL.md is roughly 11k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Bio Chipseq Qc?

Skills that share tags, products or a category with Bio Chipseq Qc: Bio Batch Processing (GPTomics/bioSkills, 1.2k stars), Bio Workflows Methylation Pipeline (GPTomics/bioSkills, 1.2k stars), Bio Proteomics Differential Abundance (GPTomics/bioSkills, 1.2k stars) and Bioconductor Harmonizr (bioMate-AI/biomate-bioconductor-kb, 804 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Bio Chipseq Qc?

FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,052 GitHub stars. The repository holds 279 skills in this directory. The repository was last updated on July 21, 2026.

Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.