Agent skill

Bioconductor Harmonizr

by bioMate-AI in bioMate-AI/biomate-bioconductor-kb

An implementation, which takes input data and makes it available for proper batch effect removal by ComBat or Limma.

Custom licenceAuto-check passedData & Analytics

Install Bioconductor Harmonizr

skills CLI
$ npx skills add bioMate-AI/biomate-bioconductor-kb --skill bioconductor-harmonizr -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install bioMate-AI/biomate-bioconductor-kb bioconductor-harmonizr --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/bioMate-AI/biomate-bioconductor-kb.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/transcriptomics/harmonizr .claude/skills/bioconductor-harmonizr && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
bioconductor-harmonizr
GitHub stars
804
Token cost
~1.2k tokens
SKILL.md length
450 words
Files
1
Skills in repo
112
Repo updated
First seen
Licence
Custom licence

At a glance

An implementation, which takes input data and makes it available for proper batch effect removal by ComBat or Limma.

  • Tasks that involve Data cleaning
  • SKILL.md covers Workflows, When to Use, When NOT to Use and Data Requirements, plus 6 more sections
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md
  • Tasks that involve Bioinformatics

What it does

Bioconductor Harmonizr is an agent skill from bioMate-AI/biomate-bioconductor-kb. An implementation, which takes input data and makes it available for proper batch effect removal by ComBat or Limma. The implementation appropriately handles missing values by dissecting the input matrix into smaller matrices with sufficient data to feed the ComBat or limma algorithm. The adjusted data is returned to the user as a rebuild matrix. The implementation is meant to make as much data available as possible with minimal data loss.

Its SKILL.md is about 1.2k tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.

It sits in Data & Analytics, covering Data cleaning and Bioinformatics. The repository describes itself as: BioMate-KB Bioconductor Skills — 200 packages (top 100 by downloads + 100 rising stars) as vignette-grounded Claude/agent skills, with per-package workflow recipes.

When your agent uses it

  • Tasks that involve Data cleaning
  • Tasks that involve Bioinformatics

Example prompts

  • “/bioconductor-harmonizr”

What it can do on your machine

Read from SKILL.md and the folder at commit c9bd4d8. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md (its code samples are r).

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    Links to these hosts (documentation or services it may open):

    • bioconductor.org

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Bioconductor Harmonizr loads about 1.2k tokens when it runs. Until then it costs about 117 tokens; SKILL.md has 450 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~117
When it runs · the whole SKILL.md, loaded when a task matches
~1.2k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Its licence (Custom licence) doesn't allow us to republish the file, so here is its outline and opening line. It has 450 words (~1,192 tokens).

“Perform batch effect correction on a data frame containing missing values using ComBat or limma.”

— opening of SKILL.md by bioMate-AI, Custom licence
name
bioconductor-harmonizr
when_to_use
Use when: An implementation, which takes input data and makes it available for proper batch effect removal by ComBat or Limma; HarmonizR_Vignette. Not for…
user-invocable
false

Read the full SKILL.md on GitHub

Files

Just SKILL.md in skills/transcriptomics/harmonizr of bioMate-AI/biomate-bioconductor-kb.

Open the folder on GitHubat commit c9bd4d8

Compare with similar skills

Bioconductor Harmonizr next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Bioconductor Harmonizr compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Bioconductor Harmonizr this skillbioMate-AI/biomate-bioconductor-kb804—~1.2kAutomated safety check: PassCustom licence
Bio Proteomics Proteomics QcFreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repos~1.8kAutomated safety check: PassNone
Bio Workflows Methylation PipelineGPTomics/bioSkills1.2k1 repos~3.7kAutomated safety check: PassMIT
Bio Proteomics Differential AbundanceGPTomics/bioSkills1.2k1 repos~5.7kAutomated safety check: PassMIT
Bio Chipseq QcFreedomIntelligence/OpenClaw-Medical-Skills3.1k—~2.7kAutomated safety check: PassNone
Bio Splicing QcFreedomIntelligence/OpenClaw-Medical-Skills3.1k—~1.6kAutomated safety check: PassNone

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Questions about Bioconductor Harmonizr

What does Bioconductor Harmonizr do?

An implementation, which takes input data and makes it available for proper batch effect removal by ComBat or Limma. Bioconductor Harmonizr is an agent skill from bioMate-AI/biomate-bioconductor-kb. An implementation, which takes input data and makes it available for proper batch effect removal by ComBat or Limma.

When should I use Bioconductor Harmonizr?

Bioconductor Harmonizr fits situations like: tasks that involve Data cleaning; tasks that involve Bioinformatics.

How do I install Bioconductor Harmonizr in Claude Code?

Run `npx skills add bioMate-AI/biomate-bioconductor-kb --skill bioconductor-harmonizr -a claude-code`. Or copy the skill folder (skills/transcriptomics/harmonizr in bioMate-AI/biomate-bioconductor-kb) into .claude/skills/bioconductor-harmonizr in your project. Claude Code loads it when a task matches its description.

How do I install Bioconductor Harmonizr in Codex?

Run `npx skills add bioMate-AI/biomate-bioconductor-kb --skill bioconductor-harmonizr -a codex`. Or copy the skill folder (skills/transcriptomics/harmonizr in bioMate-AI/biomate-bioconductor-kb) into .agents/skills/bioconductor-harmonizr in your project. Codex loads it when a task matches its description.

Can I use Bioconductor Harmonizr in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add bioMate-AI/biomate-bioconductor-kb --skill bioconductor-harmonizr -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bioconductor-harmonizr, .gemini/skills/bioconductor-harmonizr, .github/skills/bioconductor-harmonizr and .opencode/skills/bioconductor-harmonizr in your project.

What does Bioconductor Harmonizr need to run?

SKILL.md names no scripts, command-line tools or credentials: Bioconductor Harmonizr is instructions for the agent only.

Does Bioconductor Harmonizr access the network?

SKILL.md names 1 domain. As links in the text: bioconductor.org. This is read from the text; nothing was executed.

Is Bioconductor Harmonizr safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Bioconductor Harmonizr use?

Bioconductor Harmonizr has a licence file (the repository's licence) that doesn't match a standard licence. Read it on GitHub before reusing the skill.

How many tokens does Bioconductor Harmonizr use?

About 1.2k tokens (SKILL.md is roughly 4.8k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Bioconductor Harmonizr?

Skills that share tags, products or a category with Bioconductor Harmonizr: Bio Proteomics Proteomics Qc (FreedomIntelligence/OpenClaw-Medical-Skills, 3.1k stars), Bio Workflows Methylation Pipeline (GPTomics/bioSkills, 1.2k stars), Bio Proteomics Differential Abundance (GPTomics/bioSkills, 1.2k stars) and Bio Chipseq Qc (FreedomIntelligence/OpenClaw-Medical-Skills, 3.1k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Bioconductor Harmonizr?

bioMate-AI (a GitHub organization) maintains it in bioMate-AI/biomate-bioconductor-kb, which has 804 GitHub stars. The repository holds 112 skills in this directory. The repository was last updated on June 20, 2026.

Source: bioMate-AI/biomate-bioconductor-kb on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.