Agent skill

Usmle Case Generator

by aipoch in aipoch/medical-research-skills

Generate USMLE Step 1/2 style clinical cases with patient history, physical.

MITAuto-check passedResearch & Science

Install Usmle Case Generator

skills CLI
$ npx skills add aipoch/medical-research-skills --skill usmle-case-generator -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install aipoch/medical-research-skills usmle-case-generator --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/aipoch/medical-research-skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/'scientific-skills/Academic Writing/usmle-case-generator' .claude/skills/usmle-case-generator && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
usmle-case-generator
GitHub stars
2k
Token cost
~2.6k tokens
SKILL.md length
1,079 words
Files
11 (incl. scripts, references)
Skills in repo
578
Repo updated
First seen
Licence
MIT

At a glance

Generate USMLE Step 1/2 style clinical cases with patient history, physical.

  • Works in 4 steps: Confirm the user input, output path, and… → Edit the in-file CONFIG block or… → Run python scripts/main.py with the… → …
  • Research & Science work in your project
  • SKILL.md covers When to Use, Key Features, Dependencies and Example Usage, plus 20 more sections
  • Runs Python scripts from its folder; calls python

What it does

Usmle Case Generator is an agent skill from aipoch/medical-research-skills. Generate USMLE Step 1/2 style clinical cases with patient history, physical.

Its SKILL.md is about 2.6k tokens, which your agent loads only when the skill is triggered. The skill folder holds 12 other files, including scripts and reference files (for example `references/case_templates.json`, `references/guidelines.md` and `references/sample_input.json`).

It sits in Research & Science. The repository describes itself as: Hundreds of agent skills for medical research, including protocol design, data analysis, evidence insights, and academic writing. The licence is MIT.

When your agent uses it

  • Research & Science work in your project

Example prompts

  • “/usmle-case-generator”

Requirements

  • Python 3

Workflow steps

4 steps, taken from the first numbered list in SKILL.md.

  1. Confirm the user input, output path, and any required config values.
  2. Edit the in-file CONFIG block or documented parameters if the script uses fixed settings.
  3. Run python scripts/main.py with the validated inputs.
  4. Review the generated output and return the final artifact with any assumptions called out.

What it can do on your machine

Read from SKILL.md and the folder at commit 686e09d. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships 1 file in scripts/ (Python), which the agent can run.

    Shell commands in SKILL.md call:

    • python

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Usmle Case Generator loads about 2.6k tokens when it runs, and up to ~9.9k if it reads all its reference files. Until then it costs about 24 tokens; SKILL.md has 1,079 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~24
When it runs · the whole SKILL.md, loaded when a task matches
~2.6k
With references · SKILL.md plus every file in references/, read only if the agent opens them
~9.9k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); the scripts in this folder are not scanned.

SKILL.md

The full file from aipoch/medical-research-skills at commit 686e09d, republished under its MIT licence (© aipoch). 1,079 words, ~2,608 tokens.

Download SKILL.mdSave it as .claude/skills/usmle-case-generator/SKILL.md (or your agent's skills folder). This skill also uses 10 other files; get the full folder from GitHub.
name
usmle-case-generator
description
Generate USMLE Step 1/2 style clinical cases with patient history, physical.
license
MIT
author
AIPOCH

Source: https://github.com/aipoch/medical-research-skills

USMLE Case Generator

Generate USMLE Step 1 and Step 2 CK style clinical cases for medical education and board exam preparation.

When to Use

  • Use this skill when the task is to Generate USMLE Step 1/2 style clinical cases with patient history, physical.
  • Use this skill for academic writing tasks that require explicit assumptions, bounded scope, and a reproducible output format.
  • Use this skill when you need a documented fallback path for missing inputs, execution errors, or partial evidence.

Key Features

See ## Features above for related details.

  • Scope-focused workflow aligned to: Generate USMLE Step 1/2 style clinical cases with patient history, physical.
  • Packaged executable path(s): scripts/main.py.
  • Reference material available in references/ for task-specific guidance.
  • Structured execution path designed to keep outputs consistent and reviewable.

Dependencies

  • Python 3.8+
  • No external API dependencies (template-based generation)
  • Optional: LLM integration for case variation

Example Usage

See ## Usage above for related details.

bash
cd "20260318/scientific-skills/Academic Writing/usmle-case-generator"
python -m py_compile scripts/main.py
python scripts/main.py --help

Example run plan:

  1. Confirm the user input, output path, and any required config values.
  2. Edit the in-file CONFIG block or documented parameters if the script uses fixed settings.
  3. Run python scripts/main.py with the validated inputs.
  4. Review the generated output and return the final artifact with any assumptions called out.

Implementation Details

See ## Workflow above for related details.

  • Execution model: validate the request, choose the packaged workflow, and produce a bounded deliverable.
  • Input controls: confirm the source files, scope limits, output format, and acceptance criteria before running any script.
  • Primary implementation surface: scripts/main.py.
  • Reference guidance: references/ contains supporting rules, prompts, or checklists.
  • Parameters to clarify first: input path, output path, scope filters, thresholds, and any domain-specific constraints.
  • Output discipline: keep results reproducible, identify assumptions explicitly, and avoid undocumented side effects.

Quick Check

Use this command to verify that the packaged script entry point can be parsed before deeper execution.

bash
python -m py_compile scripts/main.py

Audit-Ready Commands

Use these concrete commands for validation. They are intentionally self-contained and avoid placeholder paths.

bash
python -m py_compile scripts/main.py
python scripts/main.py --help

Workflow

  1. Confirm the user objective, required inputs, and non-negotiable constraints before doing detailed work.
  2. Validate that the request matches the documented scope and stop early if the task would require unsupported assumptions.
  3. Use the packaged script path or the documented reasoning path with only the inputs that are actually available.
  4. Return a structured result that separates assumptions, deliverables, risks, and unresolved items.
  5. If execution fails or inputs are incomplete, switch to the fallback path and state exactly what blocked full completion.

Features

  • Step 1 Cases: Basic science concepts, pathophysiology, pharmacology
  • Step 2 Cases: Clinical diagnosis, management, next best steps
  • Complete Vignettes: History, physical exam, labs, imaging
  • Multiple Choice Questions: Single best answer format
  • Answer Explanations: Detailed rationale for learning

Usage

python

# Generate a Step 1 case (pathophysiology focus)
python scripts/main.py --step 1 --topic cardiology --difficulty medium

# Generate a Step 2 case (clinical management focus)
python scripts/main.py --step 2 --topic nephrology --include-diagnosis

# Generate case with specific conditions
python scripts/main.py --step 2 --condition "diabetic ketoacidosis" --format json

Parameters

ParameterOptionsDescription
--step1, 2USMLE Step level
--topicSee references/topics.jsonMedical specialty
--conditionAny conditionSpecific disease/condition
--difficultyeasy, medium, hardCase complexity
--formattext, json, markdownOutput format
--include-diagnosisflagInclude answer key
--count1-10Number of cases to generate

Topics Covered

  • Cardiology
  • Pulmonology
  • Gastroenterology
  • Nephrology
  • Endocrinology
  • Hematology/Oncology
  • Infectious Disease
  • Neurology
  • Psychiatry
  • Musculoskeletal
  • Dermatology
  • Obstetrics/Gynecology
  • Pediatrics
  • Surgery

Case Structure

Each generated case includes:

  1. Patient Demographics: Age, gender, relevant background
  2. Chief Complaint: Presenting problem
  3. History of Present Illness: Detailed symptom timeline
  4. Past Medical History: Relevant comorbidities
  5. Medications: Current drug regimen
  6. Allergies: Drug/environmental allergies
  7. Family History: Genetic conditions
  8. Social History: Smoking, alcohol, occupation
  9. Physical Examination: Vital signs, relevant findings
  10. Laboratory Studies: CBC, CMP, specific markers
  11. Imaging/Diagnostics: X-ray, CT, ECG, etc.
  12. Question: USMLE-style multiple choice
  13. Answer Options: 5 choices (A-E)
  14. Correct Answer: With detailed explanation
  15. Educational Objectives: Key learning points

Output Formats

Text Format (Default)

Plain text suitable for printing or reading.

JSON Format

Structured data for integration with applications.

Markdown Format

Formatted for documentation or web display.

Technical Difficulty

High - Requires medical knowledge validation and clinical accuracy.

⚠️ Manual Review Required: Generated cases should be reviewed by medical professionals before use in high-stakes educational settings.

Show full SKILL.md (426 more words)Show less

References

  • references/topics.json - Medical specialty taxonomy
  • references/case_templates.json - Case structure templates
  • references/usmle_patterns.md - USMLE question patterns
  • references/conditions/ - Condition-specific case data

Example Output

Case: A 58-year-old male with chest pain

A 58-year-old man presents to the emergency department with 
crushing substernal chest pain radiating to his left arm, 
beginning 2 hours ago at rest...

[History, physical, labs, ECG findings...]

Question: What is the most appropriate next step in management?

A. Administer aspirin and nitroglycerin
B. Order CT pulmonary angiography
C. Perform immediate synchronized cardioversion
D. Start heparin drip and call cardiology
E. Discharge with outpatient stress test

Correct Answer: D
Explanation: [Detailed rationale...]

Safety & Limitations

  • Cases are AI-generated and may contain inaccuracies
  • Not a substitute for professional medical education
  • Always verify clinical details with authoritative sources
  • Intended for educational purposes only

Risk Assessment

Risk IndicatorAssessmentLevel
Code ExecutionPython/R scripts executed locallyMedium
Network AccessNo external API callsLow
File System AccessRead input files, write output filesMedium
Instruction TamperingStandard prompt guidelinesLow
Data ExposureOutput files saved to workspaceLow

Security Checklist

  • No hardcoded credentials or API keys
  • No unauthorized file system access (../)
  • Output does not expose sensitive information
  • Prompt injection protections in place
  • Input file paths validated (no ../ traversal)
  • Output directory restricted to workspace
  • Script execution in sandboxed environment
  • Error messages sanitized (no stack traces exposed)
  • Dependencies audited

Prerequisites

text

# Python dependencies
pip install -r requirements.txt

Evaluation Criteria

Success Metrics
  • Successfully executes main functionality
  • Output meets quality standards
  • Handles edge cases gracefully
  • Performance is acceptable
Test Cases
  1. Basic Functionality: Standard input → Expected output
  2. Edge Case: Invalid input → Graceful error handling
  3. Performance: Large dataset → Acceptable processing time

Lifecycle Status

  • Current Stage: Draft
  • Next Review Date: 2026-03-06
  • Known Issues: None
  • Planned Improvements:
    • Performance optimization
    • Additional feature support

Output Requirements

Every final response should make these items explicit when they are relevant:

  • Objective or requested deliverable
  • Inputs used and assumptions introduced
  • Workflow or decision path
  • Core result, recommendation, or artifact
  • Constraints, risks, caveats, or validation needs
  • Unresolved items and next-step checks

Error Handling

  • If required inputs are missing, state exactly which fields are missing and request only the minimum additional information.
  • If the task goes outside the documented scope, stop instead of guessing or silently widening the assignment.
  • If scripts/main.py fails, report the failure point, summarize what still can be completed safely, and provide a manual fallback.
  • Do not fabricate files, citations, data, search results, or execution outcomes.

Input Validation

This skill accepts requests that match the documented purpose of usmle-case-generator and include enough context to complete the workflow safely.

Do not continue the workflow when the request is out of scope, missing a critical input, or would require unsupported assumptions. Instead respond:

usmle-case-generator only handles its documented workflow. Please provide the missing required inputs or switch to a more suitable skill.

Response Template

Use the following fixed structure for non-trivial requests:

  1. Objective
  2. Inputs Received
  3. Assumptions
  4. Workflow
  5. Deliverable
  6. Risks and Limits
  7. Next Checks

If the request is simple, you may compress the structure, but still keep assumptions and limits explicit when they affect correctness.

© aipoch, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

SKILL.md and 10 other files (scripts, references) in scientific-skills/Academic Writing/usmle-case-generator of aipoch/medical-research-skills.

  • SKILL.md
  • references/case_templates.json
  • references/guidelines.md
  • references/requirements.txt
  • references/sample_input.json
  • references/sample_output.json
  • references/topics.json
  • references/usmle_patterns.md
  • requirements.txt
  • scripts/main.py
  • usmle-case-generator_audit_result_v1.json

Open the folder on GitHubat commit 686e09d

Compare with similar skills

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Questions about Usmle Case Generator

What does Usmle Case Generator do?

Generate USMLE Step 1/2 style clinical cases with patient history, physical. Usmle Case Generator is an agent skill from aipoch/medical-research-skills. Generate USMLE Step 1/2 style clinical cases with patient history, physical.

When should I use Usmle Case Generator?

Usmle Case Generator fits situations like: research & Science work in your project.

How do I install Usmle Case Generator in Claude Code?

Run `npx skills add aipoch/medical-research-skills --skill usmle-case-generator -a claude-code`. Or copy the skill folder (scientific-skills/Academic Writing/usmle-case-generator in aipoch/medical-research-skills) into .claude/skills/usmle-case-generator in your project. Claude Code loads it when a task matches its description.

How do I install Usmle Case Generator in Codex?

Run `npx skills add aipoch/medical-research-skills --skill usmle-case-generator -a codex`. Or copy the skill folder (scientific-skills/Academic Writing/usmle-case-generator in aipoch/medical-research-skills) into .agents/skills/usmle-case-generator in your project. Codex loads it when a task matches its description.

Can I use Usmle Case Generator in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add aipoch/medical-research-skills --skill usmle-case-generator -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/usmle-case-generator, .gemini/skills/usmle-case-generator, .github/skills/usmle-case-generator and .opencode/skills/usmle-case-generator in your project.

What does Usmle Case Generator need to run?

Going by SKILL.md and its folder, Usmle Case Generator needs Python for the scripts in its folder and the command-line tools its instructions call (python). Our summary lists: Python 3.

Does Usmle Case Generator access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Usmle Case Generator safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. The check reads SKILL.md only: the scripts in the folder are not scanned, so read them before running anything.

What licence does Usmle Case Generator use?

Usmle Case Generator is published under the MIT licence (declared in SKILL.md). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Usmle Case Generator use?

About 2.6k tokens (SKILL.md is roughly 10k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 7.3k tokens, read only when the agent opens those files.

What are the alternatives to Usmle Case Generator?

Skills that share tags, products or a category with Usmle Case Generator: Hypothesis Generation (spacering-net/codeg, 3.9k stars), GitHub Deep Research (bytedance/deer-flow, 84k stars), Nature Paper Card (Yuan1z0825/nature-skills, 47k stars) and Content Research Writer (weapp-tailwindcss/weapp-tailwindcss, 1.9k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Usmle Case Generator?

aipoch (a GitHub organization) maintains it in aipoch/medical-research-skills, which has 1,978 GitHub stars. The repository holds 578 skills in this directory. The repository was last updated on September 17, 2026.

Source: aipoch/medical-research-skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.