Bio Clip Seq M6a Clip
GPTomics/bioSkills
Map N6-methyladenosine (m6A) RNA modifications at single-nucleotide resolution using miCLIP (Linder 2015), miCLIP2 + m6Aboost machine learning (Kortel 2021), GLORI (Liu 2023, antibody-free chemical…
A skill your agent uses when validating an existing prognostic risk signature on an external bulk expression cohort with survival outcomes, producing risk scores, Kaplan-Meier curves, risk…
$ npx skills add aipoch/medical-research-skills --skill external-model-validation -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install aipoch/medical-research-skills external-model-validation --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/aipoch/medical-research-skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/'awesome-med-research-skills/Data Analysis/external-model-validation' .claude/skills/external-model-validation && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "external-model-validation" agent skill from https://github.com/aipoch/medical-research-skills/tree/main/awesome-med-research-skills/Data%20Analysis/external-model-validation into .claude/skills/external-model-validation/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "external-model-validation", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/aipoch/medical-research-skills/tree/main/awesome-med-research-skills/Data%20Analysis/external-model-validationType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add aipoch/medical-research-skills --skill external-model-validation -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install aipoch/medical-research-skills external-model-validation --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/aipoch/medical-research-skills.git skills-src && mkdir -p .agents/skills && cp -r skills-src/'awesome-med-research-skills/Data Analysis/external-model-validation' .agents/skills/external-model-validation && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "external-model-validation" agent skill from https://github.com/aipoch/medical-research-skills/tree/main/awesome-med-research-skills/Data%20Analysis/external-model-validation into .agents/skills/external-model-validation/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "external-model-validation", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add aipoch/medical-research-skills --skill external-model-validation -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install aipoch/medical-research-skills external-model-validation --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/aipoch/medical-research-skills.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/'awesome-med-research-skills/Data Analysis/external-model-validation' .cursor/skills/external-model-validation && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "external-model-validation" agent skill from https://github.com/aipoch/medical-research-skills/tree/main/awesome-med-research-skills/Data%20Analysis/external-model-validation into .cursor/skills/external-model-validation/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "external-model-validation", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/aipoch/medical-research-skills.git --path 'awesome-med-research-skills/Data Analysis/external-model-validation'--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add aipoch/medical-research-skills --skill external-model-validation -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install aipoch/medical-research-skills external-model-validation --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/aipoch/medical-research-skills.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/'awesome-med-research-skills/Data Analysis/external-model-validation' .gemini/skills/external-model-validation && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "external-model-validation" agent skill from https://github.com/aipoch/medical-research-skills/tree/main/awesome-med-research-skills/Data%20Analysis/external-model-validation into .gemini/skills/external-model-validation/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "external-model-validation", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install aipoch/medical-research-skills external-model-validationInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add aipoch/medical-research-skills --skill external-model-validation -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/aipoch/medical-research-skills.git skills-src && mkdir -p .github/skills && cp -r skills-src/'awesome-med-research-skills/Data Analysis/external-model-validation' .github/skills/external-model-validation && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "external-model-validation" agent skill from https://github.com/aipoch/medical-research-skills/tree/main/awesome-med-research-skills/Data%20Analysis/external-model-validation into .github/skills/external-model-validation/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "external-model-validation", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add aipoch/medical-research-skills --skill external-model-validation -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install aipoch/medical-research-skills external-model-validation --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/aipoch/medical-research-skills.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/'awesome-med-research-skills/Data Analysis/external-model-validation' .opencode/skills/external-model-validation && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "external-model-validation" agent skill from https://github.com/aipoch/medical-research-skills/tree/main/awesome-med-research-skills/Data%20Analysis/external-model-validation into .opencode/skills/external-model-validation/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "external-model-validation", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
external-model-validationA skill your agent uses when validating an existing prognostic risk signature on an external bulk expression cohort with survival outcomes, producing risk scores, Kaplan-Meier curves, risk…
External Model Validation is an agent skill from aipoch/medical-research-skills. Use when validating an existing prognostic risk signature on an external bulk expression cohort with survival outcomes, producing risk scores, Kaplan-Meier curves, risk distribution plots, heatmap, and time-dependent ROC curves. NOT for: model training, feature selection, nomogram construction, calibration analysis, or single-cell data.
Its SKILL.md is about 3.2k tokens, which your agent loads only when the skill is triggered. The skill folder holds 21 other files, including scripts and reference files (for example `eval_report_external-model-validation_result.json`, `references/algorithm.md` and `references/baseline-run.md`).
It sits in Research & Science, covering Bioinformatics, Machine learning and Fine-tuning. The repository describes itself as: Hundreds of agent skills for medical research, including protocol design, data analysis, evidence insights, and academic writing. The licence is MIT.
4 steps, taken from the step headings in SKILL.md.
Read from SKILL.md and the folder at commit 686e09d. It shows what the files ask for, not the result of running them.
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Ships 6 files in scripts/ (R, from the files we listed), which the agent can run.
From the folder's file list and the shell code blocks in SKILL.md.
No URLs in SKILL.md.
From URLs in SKILL.md, links to its own repository left out.
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
External Model Validation loads about 3.2k tokens when it runs, and up to ~7.2k if it reads all its reference files. Until then it costs about 91 tokens; SKILL.md has 1,286 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); the scripts in this folder are not scanned.
The full file from aipoch/medical-research-skills at commit 686e09d, republished under its MIT licence (© aipoch). 1,286 words, ~3,176 tokens.
.claude/skills/external-model-validation/SKILL.md (or your agent's skills folder). This skill also uses 17 other files; get the full folder from GitHub.This skill accepts: an existing prognostic gene signature (model coefficient file with Gene and Coef columns), a bulk expression matrix in CSV format (genes as rows, samples as columns), and a clinical file with OS and OS.time survival columns.
If the user's request does not involve validating a pre-existing prognostic model on an external cohort — for example, asking to train a new model, perform feature selection, build a nomogram, run calibration curves, analyze single-cell data, or process data without survival endpoints — do not proceed with the workflow. Instead respond:
"external-model-validation is designed to validate an existing prognostic risk signature on an external bulk expression cohort with survival outcomes. Your request appears to be outside this scope. Please provide a fixed model coefficient file plus expression and clinical data with OS/OS.time columns, or use a more appropriate tool for model training, nomogram construction, or single-cell analysis."
| Situation | File to Read | Purpose |
|---|---|---|
| Need to run the analysis | scripts/main.R | Execute: Rscript scripts/main.R --exp_file ... --cli_file ... --model_file ... |
| Need workflow order or output generation steps | scripts/run_analysis.R | Review the 4-step orchestration of loading, scoring, plotting, and metadata export |
| Need risk score or sample matching logic | scripts/functions.R | Inspect core data preparation and validation logic |
| Need output writing or metadata export details | scripts/io.R | Inspect output directory creation and file-writing helpers |
| Need plotting implementation details | scripts/plotting.R | Inspect Kaplan-Meier, risk, heatmap, and ROC plot generation |
| Need input validation, logging, timeout, or dependency logic | scripts/utils.R | Review validation helpers, SKILL_* error handling, logging, and runtime safeguards |
| Need statistical assumptions or method details | references/algorithm.md | Risk score formula, group cutoff, survival analysis, ROC, and heatmap assumptions |
| Need troubleshooting help | references/troubleshooting.md | Common failures, warnings, and concrete fixes |
| Need CLI usage examples | references/cli-guide.md | Parameter explanations, examples, and command patterns |
| Need expected outputs or benchmark run | references/baseline-run.md | Real-data baseline command, runtime, memory checkpoints, and output inventory |
| Need test inputs | tests/data/ | Example expression, clinical, and model files for validation |
| Need to refresh the retained example output | tests/refresh_example_output.R | Rebuild tests/output/ with --overwrite using the bundled test data |
Rscript scripts/main.R \
--exp_file ./expression.csv \
--cli_file ./clinical.csv \
--model_file ./model.csv \
--output_dir ./output/ \
--time_unit month \
--seed 42| Short | Long | Type | Default | Description |
|---|---|---|---|---|
-e | --exp_file | character | required | Expression matrix CSV with genes as rows and samples as columns |
-c | --cli_file | character | required | Clinical CSV with sample IDs as row names and OS, OS.time columns |
-m | --model_file | character | required | Model coefficient CSV with Gene and Coef columns |
-o | --output_dir | character | ./output/ | Output directory |
--overwrite | flag | FALSE | Allow writing into a non-empty output directory | |
-u | --time_unit | character | month | Survival time unit in input clinical file: day, month, year |
--col_high | character | #E64B35 | Color for high-risk samples | |
--col_low | character | #4DBBD5 | Color for low-risk samples | |
--roc_cols | character | #E64B35,#00A087,#3C5488 | Comma-separated colors for ROC curves | |
--roc_times | character | 1,3,5 | Comma-separated ROC time points always in years, regardless of --time_unit. When follow-up is in days or months, still provide --roc_times in years (e.g., 1,3,5 for 1, 3, and 5 years). | |
--roc_pos | character | bottomright | ROC legend position | |
--km_breaks | integer | 0 | Kaplan-Meier x-axis break in years; 0 selects automatically | |
-s | --seed | integer | 42 | Random seed for reproducibility |
--timeout_seconds | integer | 3600 | Elapsed timeout limit in seconds |
exp_file)CSV with genes as rows and samples as columns. The first column must contain gene identifiers.
"","Sample_1","Sample_2","Sample_3"
"TSPAN6",3.87,4.54,8.12
"TNMD",9.98,5.86,5.38
"DPM1",7.95,6.11,5.41cli_file)CSV with sample IDs as row names and at least OS and OS.time columns.
,Age,OS,OS.time
Sample_1,59,0,133.5
Sample_2,60,0,49.13
Sample_3,59,1,22.40OS must use 0/1 encoding.OS.time must be positive and interpretable under --time_unit.model_file)CSV with two required columns: Gene and Coef.
Gene,Coef
TSPAN6,-0.25
TNMD,0.15
DPM1,0.32| File | Description |
|---|---|
data/risk_data.rds | Serialized analysis dataset containing survival data, model gene expression, risk scores, and risk groups |
table/out_varifyRisk.txt | Tab-delimited risk table for all matched samples |
plot/out_varifySurv.pdf | Kaplan-Meier survival curve with risk table |
plot/out_varify.riskScore.pdf | Ordered risk score plot |
plot/out_varify.survStat.pdf | Survival status plot |
plot/out_varify.heatmap.pdf | Heatmap of model genes across ordered samples |
plot/out_varify.ROC.pdf | Time-dependent ROC curve PDF |
analysis.log | Runtime log including memory checkpoints and processing steps |
run_parameters.tsv | Exact parameter values used for the run |
session_info.txt | R version, platform, and package session information |
--roc_times and --roc_cols.low and high groups using the median risk score.For sample i, the skill computes:
riskScore_i = sum(expression_ig * coefficient_g)using all genes listed in model_file.
riskScore.high; the others are labeled low.survival::survfit.survminer::ggsurvplot.timeROC::timeROC using follow-up time in years.--roc_times values must be smaller than the maximum observed follow-up time.--roc_times is always interpreted in years, regardless of --time_unit.Rscript scripts/main.R \
-e tests/data/BRCA_data.csv \
-c tests/data/BRCA_clinic.csv \
-m tests/data/BRCA_coef.csv \
-o ./output/Rscript scripts/main.R \
-e expression.csv \
-c clinical.csv \
-m model.csv \
-o ./output \
-u day \
--roc_times 1,2,3Note: --roc_times 1,2,3 means 1, 2, and 3 years — even though --time_unit day was supplied. The skill converts OS.time from days to years internally before ROC computation.
Rscript scripts/main.R \
-e expression.csv \
-c clinical.csv \
-m model.csv \
-o ./output \
--col_high '#B2182B' \
--col_low '#2166AC' \
--roc_cols '#B2182B,#4D9221,#2166AC' \
--roc_pos topleft \
--km_breaks 2| Error | Cause | Solution |
|---|---|---|
SKILL_FILE_NOT_FOUND | Input path is missing or wrong | Check file path and permissions |
SKILL_MISSING_COLUMNS | Clinical or model file lacks required columns | Ensure OS, OS.time, Gene, and Coef exist |
SKILL_SAMPLE_MISMATCH | No overlapping samples between expression and clinical data | Align sample IDs exactly |
SKILL_EMPTY_DATA | An input file is empty after loading | Verify the CSV contains at least one row and one column of usable data |
SKILL_INVALID_DATA | Duplicate genes, empty data, non-numeric coefficients, or invalid survival values. For duplicate genes: deduplicate with dplyr::distinct() or keep the row with highest mean expression (e.g., mat[order(-rowMeans(mat[,-1])),] %>% distinct(Gene, .keep_all=TRUE)) | Clean input tables and verify formats |
SKILL_ANALYSIS_ERROR | Risk groups collapse or event count is too low | Use a valid signature and cohort with enough events (minimum ~5) |
SKILL_INVALID_PARAMETER | Bad --time_unit, invalid color, or impossible ROC time point | Correct the parameter value |
SKILL_DEPENDENCY_MISSING | Required R package is not installed | Install the missing package |
SKILL_PKG_VERSION | Installed package version is below the required minimum | Upgrade the package to the required version |
IF error persists, READ: references/troubleshooting.md
# Check CLI
Rscript scripts/main.R --help
# Run with bundled test data in a fresh output directory
Rscript scripts/main.R \
-e tests/data/BRCA_data.csv \
-c tests/data/BRCA_clinic.csv \
-m tests/data/BRCA_coef.csv \
-o ./output/# Run R tests
Rscript tests/testthat.R
# Refresh the retained example output bundle
Rscript tests/refresh_example_output.R
# Inspect the generated risk table
wc -l tests/output/table/out_varifyRisk.txt
# Review the retained example outputs
ls -la tests/output/The repository stores a documented real-data baseline summary in references/baseline-run.md.
IF you need exact benchmark outputs or runtime expectations, READ: references/baseline-run.md
→ Directory structure and implementation details: references/project-structure.md
© aipoch, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file
SKILL.md and 17 other files (scripts, references) in awesome-med-research-skills/Data Analysis/external-model-validation of aipoch/medical-research-skills.
Open the folder on GitHubat commit 686e09d
External Model Validation next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| External Model Validation this skillaipoch/medical-research-skills | 2k | — | ~3.2k | Automated safety check: Pass | MIT | |
| Bio Clip Seq M6a ClipGPTomics/bioSkills | 1.2k | 2 repos | ~5.7k | Automated safety check: Pass | MIT | |
| Gtars Genomic Interval Toolkitdavila7/claude-code-templates | 32k | 12 repos | ~1.9k | Automated safety check: Pass | MIT | |
| Bio Imaging Mass Cytometry Data PreprocessingGPTomics/bioSkills | 1.2k | 1 repos | ~4.2k | Automated safety check: Pass | MIT | |
| Bio Proteomics Spectral LibrariesGPTomics/bioSkills | 1.2k | 1 repos | ~4.6k | Automated safety check: Pass | MIT | |
| Bio Temporal Genomics Temporal GrnGPTomics/bioSkills | 1.2k | 1 repos | ~5k | Automated safety check: Pass | MIT |
GPTomics/bioSkills
Map N6-methyladenosine (m6A) RNA modifications at single-nucleotide resolution using miCLIP (Linder 2015), miCLIP2 + m6Aboost machine learning (Kortel 2021), GLORI (Liu 2023, antibody-free chemical…
davila7/claude-code-templates
Works with genomic intervals using gtars, a Rust toolkit with Python bindings: overlap detection, coverage tracks, tokenization for ML models and reference sequences.
GPTomics/bioSkills
Load and preprocess imaging mass cytometry (IMC) and MIBI data from raw MCD/TXT through hot-pixel removal, spillover compensation, and variance-stabilizing transformation, covering readimc/steinbock…
GPTomics/bioSkills
Builds and manages DIA spectral libraries as peptide query parameters (precursor m/z, a few fragment m/z plus relative intensities, normalized RT, optional CCS), covering experimental DDA…
GPTomics/bioSkills
Infers directed, time-delayed gene regulatory edges from BULK time-series expression using Granger causality (statsmodels VAR F-test), dynGENIE3 (tree ensembles regressing ODE-derived derivatives…
jaechang-hits/SciAgent-Skills
Consensus cell type annotation: runs 10+ algorithms (KNN-Harmony/BBKNN/Scanorama/scVI, CellTypist, ONCLASS, Random Forest, SCANVI, SVM, XGBoost) on a labeled reference and transfers labels via…
aipoch/medical-research-skills
Complete workflow for generating academic research posters from PDF literature; use when you need to extract paper content from PDFs and produce a LaTeX-based poster…
aipoch/medical-research-skills
Analyzes clinical diagnostic accuracy studies for bias using the QUADAS-2 tool.
aipoch/medical-research-skills
Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats.
aipoch/medical-research-skills
A toolkit for preparing ISO 13485:2016 certification documentation for medical device QMS.
aipoch/medical-research-skills
Recommends target journals for manuscript submission by analyzing the paper topic/abstract and the journal distribution of similar PubMed literature; use when users ask for journal…
aipoch/medical-research-skills
Creates academic-poster writing packages for LaTeX using beamerposter, tikzposter, or baposter.
Categories
A skill your agent uses when validating an existing prognostic risk signature on an external bulk expression cohort with survival outcomes, producing risk scores, Kaplan-Meier curves, risk…. External Model Validation is an agent skill from aipoch/medical-research-skills. Use when validating an existing prognostic risk signature on an external bulk expression cohort with survival outcomes, producing risk scores, Kaplan-Meier curves, risk distribution plots, heatmap, and time-dependent ROC curves.
External Model Validation fits situations like: validating an existing prognostic risk signature on an external bulk expression cohort with survival outcomes; producing risk scores; kaplan-Meier curves; risk distribution plots.
Run `npx skills add aipoch/medical-research-skills --skill external-model-validation -a claude-code`. Or copy the skill folder (awesome-med-research-skills/Data Analysis/external-model-validation in aipoch/medical-research-skills) into .claude/skills/external-model-validation in your project. Claude Code loads it when a task matches its description.
Run `npx skills add aipoch/medical-research-skills --skill external-model-validation -a codex`. Or copy the skill folder (awesome-med-research-skills/Data Analysis/external-model-validation in aipoch/medical-research-skills) into .agents/skills/external-model-validation in your project. Codex loads it when a task matches its description.
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add aipoch/medical-research-skills --skill external-model-validation -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/external-model-validation, .gemini/skills/external-model-validation, .github/skills/external-model-validation and .opencode/skills/external-model-validation in your project.
Going by SKILL.md and its folder, External Model Validation needs R for the scripts in its folder.
SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. The check reads SKILL.md only: the scripts in the folder are not scanned, so read them before running anything.
External Model Validation is published under the MIT licence (declared in SKILL.md). It allows redistribution, so the full SKILL.md is shown on this page.
About 3.2k tokens (SKILL.md is roughly 13k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 4.1k tokens, read only when the agent opens those files.
Skills that share tags, products or a category with External Model Validation: Bio Clip Seq M6a Clip (GPTomics/bioSkills, 1.2k stars), Gtars Genomic Interval Toolkit (davila7/claude-code-templates, 32k stars), Bio Imaging Mass Cytometry Data Preprocessing (GPTomics/bioSkills, 1.2k stars) and Bio Proteomics Spectral Libraries (GPTomics/bioSkills, 1.2k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
aipoch (a GitHub organization) maintains it in aipoch/medical-research-skills, which has 1,973 GitHub stars. The repository holds 567 skills in this directory. The repository was last updated on September 17, 2026.
Source: aipoch/medical-research-skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.