InternScience/scp

Given an rsID, query multiple databases (dbSNP, FAVOR, GWAS Catalog, ClinVar, gnomAD, PharmGKB, ClinGen) for comprehensive annotation.

InternScience/scp

Calculate atmospheric parameters including Coriolis parameter, geostrophic wind, heat index, potential temperature, and dewpoint for meteorology and climate science.

InternScience/scp

Search biomedical literature and web content using Tavily search engine for research and clinical information.

InternScience/scp

Calculate buoyancy forces and acceleration for fluid mechanics and hydrodynamics analysis.

InternScience/scp

Calculate electrical capacitance from geometric parameters and dielectric properties for circuit design.

InternScience/scp

Search ChEMBL database for molecule information by name to retrieve bioactivity data and chemical structures.

InternScience/scp

Predict protein-ligand binding affinity using Boltz-2 model to assess molecular interactions and binding probability for drug discovery.

InternScience/scp

Calculate mass percentages and stoichiometric ratios for chemical reactions and compound compositions.

InternScience/scp

Analyze chemical structures from compound names to retrieve SMILES, molecular formulas, molecular weight, and LogP values.

InternScience/scp

Retrieve SMILES strings from PubChem database using compound names to obtain molecular structures from common chemical names.

InternScience/scp

Comprehensive protein analysis combining InterProScan domain identification with BLAST similarity search to provide complete functional and evolutionary annotation.

InternScience/scp

Predict a molecule's ability to reverse disease states using DLEPS (Disease-Ligand Embedding Projection Score) for drug repositioning and discovery.

InternScience/scp

Use ESMFold model to predict 3D structure of the input protein sequence.

InternScience/scp

Given a protein sequence and its structure, employ ProSST model to predict mutation effects and obtain the top-k mutated sequences.

InternScience/scp

Analyze DNA and RNA sequences including molecular weight calculation, reverse complement generation, and oligonucleotide properties.

InternScience/scp

Comprehensive drug screening pipeline from molecular filtering through QED/ADMET criteria to protein-ligand docking, identifying promising drug candidates.

InternScience/scp

Predict the ADMET (absorption, distribution, metabolism, excretion, and toxicity) properties of the input molecules.

InternScience/scp

Retrieve SMILES strings from PubChem using compound names. An agent skill from InternScience/scp.

InternScience/scp

Check if the input protein sequence or molecule SMILES string is valid.

InternScience/scp

Calculate disease reversal scores for the provided molecules relative to a specific disease.

InternScience/scp

Compute the drug-likeness metrics (QED score and Number of violations of Lipinski's Rule of Five) of the input candidate molecules (SMILES format).

InternScience/scp

Implement data transmission between the local computer and the MCP Server using Base64 encoding

InternScience/scp

Generate new molecules sampling from the input two warhead fragments.

InternScience/scp

Calculate different types of molecular properties based on SMILES strings, covering basic physicochemical properties, hydrophobicity, hydrogen bonding capability, molecular complexity, topological…

InternScience/scp

Compute the Tanimoto similarities between a target molecule and a list of candidate molecules using Morgan fingerprints.

InternScience/scp

Generate new molecules sampling from the input molecule. An agent skill from InternScience/scp.

InternScience/scp

Generate new peptide molecules sampling from the input peptide sequence.

InternScience/scp

Generate new molecules sampling from the input scaffold. An agent skill from InternScience/scp.

InternScience/scp

Search the protein information from the input gene name and downloads the optimal PDB or AlphaFold structures.

InternScience/scp

Retrieve genomic sequences from Ensembl database using transcript or gene IDs to obtain nucleotide and protein sequences.

InternScience/scp

Assess drug risks and adverse effects using FDA drug database to retrieve safety information and risk profiles.

InternScience/scp

Given a gene symbol (e.g. An agent skill from InternScience/scp.

InternScience/scp

Calculate volumes of geometric shapes for engineering design and mathematical analysis.

InternScience/scp

Analyze protein sequences using InterProScan to identify functional domains, protein families, and Gene Ontology (GO) annotations.

InternScience/scp

Search KEGG database for gene information to retrieve pathway associations, functional annotations, and disease links.

InternScience/scp

Calculate material density and volume from mass and geometric dimensions for materials mechanics analysis.

InternScience/scp

Analyze measurement errors, uncertainties, and statistical variations in experimental data for quality control.

InternScience/scp

Perform meta-analysis on scientific studies to synthesize research findings and generate comprehensive reports with statistical summaries.

InternScience/scp

Calculate advanced molecular descriptors including shape indices, connectivity indices, and structural features for QSAR and drug discovery.

InternScience/scp

Convert between molecular formats including SMILES, InChI, InChIKey, and SELFIES for cheminformatics applications.

InternScience/scp

Calculate basic molecular properties from SMILES including molecular weight, formula, atom counts, and exact mass.

InternScience/scp

Comprehensive molecular property analysis covering basic info, hydrophobicity, H-bonding, structural complexity, topology, drug-likeness, charge distribution, and complexity metrics.

InternScience/scp

Search for similar molecules using Tanimoto similarity with Morgan fingerprints to identify structurally related compounds.

InternScience/scp

Retrieve gene information from NCBI Gene database by gene IDs to obtain genomic details, function, and expression data.

InternScience/scp

Calculate seawater thermodynamic properties using TEOS-10 standard including density, salinity, sound speed, and freezing temperature for oceanography.

InternScience/scp

Retrieve disease-associated targets from Open Targets using disease EFO IDs to identify therapeutic targets.

InternScience/scp

Calculate optical frequency and wavelength relationships for photonics and electromagnetic analysis.

InternScience/scp

Calculate peptide sequence properties including molecular weight, isoelectric point, extinction coefficient, and chemical formula.

InternScience/scp