Agent skill

Dna Rna Sequence Analysis

Analyze DNA and RNA sequences including molecular weight calculation, reverse complement generation, and oligonucleotide properties.

MITAuto-check passed

Install Dna Rna Sequence Analysis

skills CLI

$ npx skills add InternScience/scp --skill dna-rna-sequence-analysis -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI

$ gh skill install InternScience/scp dna-rna-sequence-analysis --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy

$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/dna-rna-sequence-analysis .claude/skills/dna-rna-sequence-analysis && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Paste into Claude Code

Install the "dna-rna-sequence-analysis" agent skill from https://github.com/InternScience/scp/tree/main/skills/dna-rna-sequence-analysis into .claude/skills/dna-rna-sequence-analysis/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "dna-rna-sequence-analysis", then confirm the skill loads.

Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

$skill-installer

$skill-installer install https://github.com/InternScience/scp/tree/main/skills/dna-rna-sequence-analysis

Type this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.

skills CLI

$ npx skills add InternScience/scp --skill dna-rna-sequence-analysis -a codex

Project install goes to .agents/skills/; add -g for ~/.codex/skills/.

GitHub CLI

$ gh skill install InternScience/scp dna-rna-sequence-analysis --agent codex

Project scope by default (.agents/skills/); add --scope user for a personal install.

Manual copy

$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .agents/skills && cp -r skills-src/skills/dna-rna-sequence-analysis .agents/skills/dna-rna-sequence-analysis && rm -rf skills-src

Use ~/.agents/skills/ instead of .agents/skills for a personal install.

Codex skills documentation · loads skills from .agents/skills/

Paste into Codex

Install the "dna-rna-sequence-analysis" agent skill from https://github.com/InternScience/scp/tree/main/skills/dna-rna-sequence-analysis into .agents/skills/dna-rna-sequence-analysis/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "dna-rna-sequence-analysis", then confirm the skill loads.

Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

skills CLI

$ npx skills add InternScience/scp --skill dna-rna-sequence-analysis -a cursor

Project install goes to .agents/skills/; add -g for ~/.cursor/skills/.

GitHub CLI

$ gh skill install InternScience/scp dna-rna-sequence-analysis --agent cursor

Project scope by default (.agents/skills/); add --scope user for a personal install.

Manual copy

$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/skills/dna-rna-sequence-analysis .cursor/skills/dna-rna-sequence-analysis && rm -rf skills-src

Use ~/.cursor/skills/ instead of .cursor/skills for a personal install.

Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/

Paste into Cursor

Install the "dna-rna-sequence-analysis" agent skill from https://github.com/InternScience/scp/tree/main/skills/dna-rna-sequence-analysis into .cursor/skills/dna-rna-sequence-analysis/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "dna-rna-sequence-analysis", then confirm the skill loads.

Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

gemini skills install

$ gemini skills install https://github.com/InternScience/scp.git --path skills/dna-rna-sequence-analysis

--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.

skills CLI

$ npx skills add InternScience/scp --skill dna-rna-sequence-analysis -a gemini-cli

Project install goes to .agents/skills/; add -g for ~/.gemini/skills/.

GitHub CLI

$ gh skill install InternScience/scp dna-rna-sequence-analysis --agent gemini-cli

Project scope by default (.agents/skills/); add --scope user for a personal install.

Manual copy

$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/skills/dna-rna-sequence-analysis .gemini/skills/dna-rna-sequence-analysis && rm -rf skills-src

Use ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.

Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/

Paste into Gemini CLI

Install the "dna-rna-sequence-analysis" agent skill from https://github.com/InternScience/scp/tree/main/skills/dna-rna-sequence-analysis into .gemini/skills/dna-rna-sequence-analysis/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "dna-rna-sequence-analysis", then confirm the skill loads.

Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

GitHub CLI

$ gh skill install InternScience/scp dna-rna-sequence-analysis

Installs for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).

skills CLI

$ npx skills add InternScience/scp --skill dna-rna-sequence-analysis -a github-copilot

Project install goes to .agents/skills/; add -g for ~/.copilot/skills/.

Manual copy

$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .github/skills && cp -r skills-src/skills/dna-rna-sequence-analysis .github/skills/dna-rna-sequence-analysis && rm -rf skills-src

Use ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.

GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/

Paste into GitHub Copilot

Install the "dna-rna-sequence-analysis" agent skill from https://github.com/InternScience/scp/tree/main/skills/dna-rna-sequence-analysis into .github/skills/dna-rna-sequence-analysis/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "dna-rna-sequence-analysis", then confirm the skill loads.

GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

skills CLI

$ npx skills add InternScience/scp --skill dna-rna-sequence-analysis -a opencode

OpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.

GitHub CLI

$ gh skill install InternScience/scp dna-rna-sequence-analysis --agent opencode

Project scope by default (.agents/skills/); add --scope user for a personal install.

Manual copy

$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/skills/dna-rna-sequence-analysis .opencode/skills/dna-rna-sequence-analysis && rm -rf skills-src

Use ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.

OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/

Paste into OpenCode

Install the "dna-rna-sequence-analysis" agent skill from https://github.com/InternScience/scp/tree/main/skills/dna-rna-sequence-analysis into .opencode/skills/dna-rna-sequence-analysis/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "dna-rna-sequence-analysis", then confirm the skill loads.

OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

Facts

Skill name: dna-rna-sequence-analysis
GitHub stars: 169
Used in: 1 other repo
Token cost: ~1.4k tokens
SKILL.md length: 356 words
Files: 1
Skills in repo: 73
Repo updated: Jun 3, 2026
First seen: Oct 7, 2026
Licence: MIT

At a glance

Analyze DNA and RNA sequences including molecular weight calculation, reverse complement generation, and oligonucleotide properties.

Works in 2 steps: MCP Server Definition → DNA/RNA Sequence Analysis Workflow
Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Dna Rna Sequence Analysis is an agent skill from InternScience/scp. Analyze DNA and RNA sequences including molecular weight calculation, reverse complement generation, and oligonucleotide properties.

Its SKILL.md is about 1.4k tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.

The licence is MIT.

Example prompts

“/dna-rna-sequence-analysis”

Requirements

Python 3

Workflow steps

2 steps, taken from the step headings in SKILL.md.

MCP Server Definition
DNA/RNA Sequence Analysis Workflow

What it can do on your machine

Read from SKILL.md and the folder at commit cea5398. It shows what the files ask for, not the result of running them.

Tool permissions
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Runs code
No scripts in the folder and no shell commands in SKILL.md (its code samples are python).
From the folder's file list and the shell code blocks in SKILL.md.
Network
No URLs in SKILL.md.
From URLs in SKILL.md, links to its own repository left out.
Credentials
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Dna Rna Sequence Analysis loads about 1.4k tokens when it runs. Until then it costs about 40 tokens; SKILL.md has 356 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it: ~40
When it runs · the whole SKILL.md, loaded when a task matches: ~1.4k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from InternScience/scp at commit cea5398, republished under its MIT licence (© InternScience). 356 words, ~1,366 tokens.

Download SKILL.mdSave it as .claude/skills/dna-rna-sequence-analysis/SKILL.md (or your agent's skills folder).

name: dna-rna-sequence-analysis
description: Analyze DNA and RNA sequences including molecular weight calculation, reverse complement generation, and oligonucleotide properties.
license: MIT license
metadata.skill-author: PJLab

DNA/RNA Sequence Analysis

Usage

1. MCP Server Definition

Use the same BiologyToolsClient class as defined in the protein-properties-calculation skill.

2. DNA/RNA Sequence Analysis Workflow

This workflow analyzes DNA and RNA sequences, calculating molecular weight, GC content, melting temperature, and generating reverse complements.

Workflow Steps:

Calculate DNA Molecular Weight - Compute molecular weight for DNA sequences
Calculate Oligonucleotide Properties - Compute GC content, Tm, extinction coefficient for RNA
Generate Reverse Complement - Create reverse complement sequence

Implementation:

python

## Initialize client
HEADERS = {"SCP-HUB-API-KEY": "<your-api-key>"}

client = BiologyToolsClient(
    "https://scp.intern-ai.org.cn/api/v1/mcp/29/SciToolAgent-Bio",
    HEADERS
)

if not await client.connect():
    print("connection failed")
    exit()

print("=== DNA/RNA Sequence Analysis ===\n")

## Step 1: Calculate DNA molecular weight
print("Step 1: DNA Molecular Weight")
dna_sequence = "ATGATGTAACGTAGCTAG"
sequence_para = f"seq1:{dna_sequence}.strand=single,topology=linear"

result = await client.client.call_tool(
    "DNAMolecularWeightCalculator",
    arguments={"sequence_para": sequence_para}
)
result_data = client.parse_result(result)
print(f"DNA Sequence: {dna_sequence}")
print(f"Result:\n{result_data}\n")

## Step 2: Calculate oligonucleotide (RNA) properties
print("Step 2: Oligonucleotide (RNA) Properties")
rna_sequence = "AUGAUGUAACGUAGCUAG"

result = await client.client.call_tool(
    "CalculatorOligonucleotide",
    arguments={"sq": rna_sequence}
)
result_data = client.parse_result(result)
print(f"RNA Sequence: {rna_sequence}")
print(f"Result:\n{result_data}\n")

## Step 3: Generate reverse complement
print("Step 3: Reverse Complement")
test_sequence = "ATCGATCG"

result = await client.client.call_tool(
    "GetReverseComplement",
    arguments={"sequence": test_sequence}
)
result_data = client.parse_result(result)
print(f"Original Sequence: {test_sequence}")
print(f"Reverse Complement:\n{result_data}\n")

## Step 4: Calculate annealing temperature for primers
print("Step 4: PCR Primer Annealing Temperature")
primer_sequence = "GCTAGCTAGCTA"

result = await client.client.call_tool(
    "ComputeAnnealingTemperature",
    arguments={"sequence": primer_sequence}
)
result_data = client.parse_result(result)
print(f"Primer Sequence: {primer_sequence}")
print(f"Result:\n{result_data}\n")

await client.disconnect()

Tool Descriptions

SciToolAgent-Bio Server:

DNAMolecularWeightCalculator: Calculate DNA molecular weight
- Args: sequence_para (str) - Formatted sequence with parameters
- Format: "seqName:SEQUENCE.strand=single/double,topology=linear/circular"
- Returns: Molecular weight in Daltons
CalculatorOligonucleotide: Calculate oligonucleotide (RNA) properties
- Args: sq (str) - RNA sequence
- Returns: GC content (%), Tm (°C), molecular weight, extinction coefficient
GetReverseComplement: Generate reverse complement sequence
- Args: sequence (str) - DNA sequence
- Returns: Reverse complement sequence
ComputeAnnealingTemperature: Calculate primer annealing temperature
- Args: sequence (str) - Primer sequence
- Returns: Annealing temperature for PCR

Input/Output

Input:

DNA sequences: Use A, T, G, C nucleotides
RNA sequences: Use A, U, G, C nucleotides
Sequence parameters for DNA: strand type (single/double) and topology (linear/circular)

Output:

DNA Molecular Weight: Mass in Daltons for DNA sequences
GC Content: Percentage of G and C nucleotides
Tm (Melting Temperature): Temperature at which 50% of DNA is denatured
Extinction Coefficient: For nucleic acid quantification (M⁻¹cm⁻¹)
Reverse Complement: Complementary antiparallel sequence

Show full SKILL.md (140 more words)Show less

Use Cases

Design PCR primers with appropriate annealing temperatures
Calculate oligonucleotide concentrations spectrophotometrically
Generate reverse complement for sequencing analysis
Analyze GC content for primer design
Plan molecular cloning experiments
Estimate DNA/RNA molecular weights
Design and analyze synthetic oligonucleotides

Sequence Format for DNA Molecular Weight

Format: "seqName:SEQUENCE.strand=X,topology=Y"

Parameters:

seqName: Identifier for the sequence
SEQUENCE: DNA nucleotide sequence (A, T, G, C)
strand: Either "single" or "double"
topology: Either "linear" or "circular"

Example: "plasmid1:ATGCATGC.strand=double,topology=circular"

GC Content and Tm

High GC content (>60%): Higher melting temperature, more stable
Low GC content (<40%): Lower melting temperature, less stable
Tm: Used to determine PCR annealing temperature (typically Tm - 5°C)

Additional DNA/RNA Tools Available

ORFFind: Find open reading frames
TranslateDNAtoAminoAcidSequence: Translate DNA to protein
RepeatDNASequenceSearch: Find repetitive sequences
CpGIslandPrediction: Predict CpG islands
PCRPrimerProperties: Analyze primer properties
RandomDNAGeneration: Generate random DNA sequences
CircularDNAAlignment: Align circular DNA sequences

Files

Just SKILL.md in skills/dna-rna-sequence-analysis of InternScience/scp.

Open the folder on GitHubat commit cea5398

Used in 2 other repositories

We found 2 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in InternScience/scp, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Dna Rna Sequence Analysis next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Dna Rna Sequence Analysis compared with similar skills
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Dna Rna Sequence Analysis this skillInternScience/scp	169	1 repos	~1.4k	Automated safety check: Pass	MIT	4 mo ago
Page Weightthedaviddias/Front-End-Checklist	74k	—	~428	Automated safety check: Pass	MIT	2 days ago
Molecular DynamicsK-Dense-AI/scientific-agent-skills	48k	1 repos	~4.7k	Automated safety check: Pass	MIT	3 days ago
Eol Resistor Calculatorsickn33/agentic-awesome-skills	47k	1 repos	~3.5k	Automated safety check: Pass	MIT	yesterday
Sequencesvellum-ai/vellum-assistant	1.4k	—	~589	Automated safety check: Pass	MIT	yesterday
Bio Sequence PropertiesGPTomics/bioSkills	1.2k	1 repos	~4k	Automated safety check: Pass	MIT	1 mo ago

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Questions about Dna Rna Sequence Analysis

What does Dna Rna Sequence Analysis do?

Analyze DNA and RNA sequences including molecular weight calculation, reverse complement generation, and oligonucleotide properties. Dna Rna Sequence Analysis is an agent skill from InternScience/scp. Analyze DNA and RNA sequences including molecular weight calculation, reverse complement generation, and oligonucleotide properties.

How do I install Dna Rna Sequence Analysis in Claude Code?

Run `npx skills add InternScience/scp --skill dna-rna-sequence-analysis -a claude-code`. Or copy the skill folder (skills/dna-rna-sequence-analysis in InternScience/scp) into .claude/skills/dna-rna-sequence-analysis in your project. Claude Code loads it when a task matches its description.

How do I install Dna Rna Sequence Analysis in Codex?

Run `npx skills add InternScience/scp --skill dna-rna-sequence-analysis -a codex`. Or copy the skill folder (skills/dna-rna-sequence-analysis in InternScience/scp) into .agents/skills/dna-rna-sequence-analysis in your project. Codex loads it when a task matches its description.

Can I use Dna Rna Sequence Analysis in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add InternScience/scp --skill dna-rna-sequence-analysis -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/dna-rna-sequence-analysis, .gemini/skills/dna-rna-sequence-analysis, .github/skills/dna-rna-sequence-analysis and .opencode/skills/dna-rna-sequence-analysis in your project.

What does Dna Rna Sequence Analysis need to run?

SKILL.md names no scripts, command-line tools or credentials: Dna Rna Sequence Analysis is instructions for the agent only. Our summary lists: Python 3.

Does Dna Rna Sequence Analysis access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Dna Rna Sequence Analysis safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Dna Rna Sequence Analysis use?

Dna Rna Sequence Analysis is published under the MIT licence (declared in SKILL.md). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Dna Rna Sequence Analysis use?

About 1.4k tokens (SKILL.md is roughly 5.5k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Dna Rna Sequence Analysis?

Skills that share tags, products or a category with Dna Rna Sequence Analysis: Page Weight (thedaviddias/Front-End-Checklist, 74k stars), Molecular Dynamics (K-Dense-AI/scientific-agent-skills, 48k stars), Eol Resistor Calculator (sickn33/agentic-awesome-skills, 47k stars) and Sequences (vellum-ai/vellum-assistant, 1.4k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Dna Rna Sequence Analysis?

InternScience (a GitHub organization) maintains it in InternScience/scp, which has 169 GitHub stars. The repository holds 73 skills in this directory. The repository was last updated on June 3, 2026.

Source: InternScience/scp on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.

Install Dna Rna Sequence Analysis

Facts

At a glance

What it does

Example prompts

Requirements

Workflow steps

What it can do on your machine

Tool permissions

Runs code

Network

Credentials

Context cost

Safety

SKILL.md

DNA/RNA Sequence Analysis

Usage

1. MCP Server Definition

2. DNA/RNA Sequence Analysis Workflow

Tool Descriptions

Input/Output

Use Cases

Sequence Format for DNA Molecular Weight

GC Content and Tm

Additional DNA/RNA Tools Available

Files

Used in 2 other repositories

Compare with similar skills

Similar skills

More from InternScience/scp

Questions about Dna Rna Sequence Analysis