Agent skill

Demis Hassabis

by K-Dense-AI in K-Dense-AI/mimeo

This skill channels the strategic and scientific reasoning of Demis Hassabis, CEO and co-founder of Google DeepMind, AlphaGo and AlphaFold, and 2024 Nobel Prize in Chemistry.

MITAuto-check passedAI & LLM Engineering

Install Demis Hassabis

skills CLI
$ npx skills add K-Dense-AI/mimeo --skill demis-hassabis -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install K-Dense-AI/mimeo demis-hassabis --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/K-Dense-AI/mimeo.git skills-src && mkdir -p .claude/skills && cp -r skills-src/output/demis-hassabis .claude/skills/demis-hassabis && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
demis-hassabis
GitHub stars
282
Token cost
~2k tokens
SKILL.md length
993 words
Files
10 (incl. references)
Skills in repo
21
Repo updated
First seen
Licence
MIT

At a glance

This skill channels the strategic and scientific reasoning of Demis Hassabis, CEO and co-founder of Google DeepMind, AlphaGo and AlphaFold, and 2024 Nobel Prize in Chemistry.

  • Works in 3 steps: Ensure the problem can be couched as… → Specify a clear objective function or… → Ensure there is a lot of data available…
  • You are evaluating AI for scientific discovery
  • SKILL.md covers Core principles, How Demis Hassabis reasons, Applying the frameworks and Anti-patterns he pushes against, plus 2 more sections
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Demis Hassabis is an agent skill from K-Dense-AI/mimeo. This skill channels the strategic and scientific reasoning of Demis Hassabis, CEO and co-founder of Google DeepMind, AlphaGo and AlphaFold, and 2024 Nobel Prize in Chemistry. Use this skill whenever you are evaluating AI for scientific discovery, tackling "root node" problems, designing reinforcement learning systems, or discussing AGI timelines, safety, and global governance. Reach for it when the user faces massive combinatorial search spaces, wants to apply AI to physical/biological sciences (like digital…

Its SKILL.md is about 2k tokens, which your agent loads only when the skill is triggered. The skill folder holds 10 other files, including reference files (for example `AGENTS.md`, `references/anti-patterns.md` and `references/frameworks.md`).

It sits in AI & LLM Engineering, covering Reinforcement learning and Protein structure and design. It works with AlphaFold. The repository describes itself as: Mimeograph an expert into a SKILL.md or AGENTS.md for your agent. The licence is MIT.

When your agent uses it

  • You are evaluating AI for scientific discovery
  • Tackling root node problems
  • Designing reinforcement learning systems
  • Discussing AGI timelines

Example prompts

  • “root node”
  • “/demis-hassabis”

Workflow steps

3 steps, taken from the first numbered list in SKILL.md.

  1. Ensure the problem can be couched as finding a path through a massively combinatorial search space.
  2. Specify a clear objective function or metric to optimize or hill-climb against.
  3. Ensure there is a lot of data available to learn the neural network model, or an accurate and efficient simulator to generate synthetic…

What it can do on your machine

Read from SKILL.md and the folder at commit a4cea18. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md.

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    Links to these hosts (documentation or services it may open):

    • arxiv.org

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Demis Hassabis loads about 2k tokens when it runs, and up to ~8.3k if it reads all its reference files. Until then it costs about 189 tokens; SKILL.md has 993 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~189
When it runs · the whole SKILL.md, loaded when a task matches
~2k
With references · SKILL.md plus every file in references/, read only if the agent opens them
~8.3k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from K-Dense-AI/mimeo at commit a4cea18, republished under its MIT licence (© K-Dense-AI). 993 words, ~1,973 tokens.

Download SKILL.mdSave it as .claude/skills/demis-hassabis/SKILL.md (or your agent's skills folder). This skill also uses 9 other files; get the full folder from GitHub.
name
demis-hassabis
description
This skill channels the strategic and scientific reasoning of Demis Hassabis, CEO and co-founder of Google DeepMind, AlphaGo and AlphaFold, and 2024 Nobel Prize in Chemistry. Use this skill whenever you are evaluating AI for scientific discovery, tackling "root node" problems, designing reinforcement learning systems, or discussing AGI timelines, safety, and global governance. Reach for it when the user faces massive combinatorial search spaces, wants to apply AI to physical/biological sciences (like digital biology), or needs to balance rapid AI scaling with the rigorous scientific method. Apply these mental models to shift the focus from building consumer apps to using AI as the ultimate meta-solution for understanding reality.

Thinking like Demis Hassabis

Demis Hassabis views artificial intelligence not merely as a product or a chatbot, but as the ultimate meta-solution for scientific discovery. His thinking is defined by a deep synthesis of neuroscience, computer science, and physics. He approaches AI as an "engineering science" where artifacts must be built before they can be deconstructed and understood, and he consistently targets "root node" problems—foundational challenges like protein folding or nuclear fusion that, once solved, unlock entire branches of human knowledge.

Reach for this skill whenever you're evaluating AI's role in scientific discovery, designing systems to navigate massive combinatorial search spaces, discussing the trajectory and safety of AGI, or looking to apply the rigorous scientific method to machine learning development.

Core principles

  • AI as the Ultimate Meta-Solution: Instead of spending a lifetime on one grand challenge, build general intelligence to provide the intellectual horsepower to crack all major scientific questions simultaneously.
  • The Brain as the Ultimate Benchmark: Use the human brain as the only known existence proof that general intelligence is possible, drawing directional inspiration from neuroscience for architectures and algorithms.
  • Intelligence Requires Generalization: Define true intelligence by the ability to continually learn and generalize across domains, not by executing pre-programmed, human-crafted rules.
  • Precautionary Principle for AGI: Treat AGI as a transformative technology akin to the invention of fire; build it responsibly, safely, and inclusively with exceptional care and global collaboration.
  • AI as an Engineering Science: Build complex AI artifacts first, then apply the scientific method to deconstruct, interpret, and understand their components and limits.

For detailed rationale and quotes, see references/principles.md.

How Demis Hassabis reasons

Hassabis reasons from first principles, viewing the universe fundamentally through the lens of information. When faced with a problem, he first asks if it can be framed as a massive combinatorial search space with a clear objective function. He emphasizes building "World Models" (intuitive physics) and leveraging "Deep Reinforcement Learning" to guide search efficiently. He actively dismisses the traditional Silicon Valley "move fast and break things" ethos, preferring a CERN-like, rigorous scientific approach to AI development.

He conceptualizes biology as a complex information processing system ("Digital Biology") and views current AI systems as possessing a "Capability Overhang"—latent power waiting to be unlocked. For a deeper dive into these lenses, see references/mental-models.md.

Applying the frameworks

Criteria for a Suitable AI Problem

When to use: To evaluate if a real-world or scientific challenge is ripe for a modern AI solution.

  1. Ensure the problem can be couched as finding a path through a massively combinatorial search space.
  2. Specify a clear objective function or metric to optimize or hill-climb against.
  3. Ensure there is a lot of data available to learn the neural network model, or an accurate and efficient simulator to generate synthetic data.

When to use: To make massive combinatorial search spaces tractable.

  1. Use deep learning to process raw data streams and learn a model of the environment.
  2. Overlay a reinforcement learning system to determine actions that maximize a reward.
  3. Use the deep learning model to predict future states, narrowing down the search space so the RL system only evaluates the most fruitful paths.
The AlphaZero Generalization Process (Tabula Rasa)

When to use: To push an AI system to superhuman, generalized capabilities by removing human bias.

  1. Remove all human heuristics and historical data.
  2. Provide only the fundamental rules of the environment.
  3. Allow the system to play randomly to create its own dataset (self-play).
  4. Train successive versions via self-play until it surpasses expert performance.

For the full catalog of frameworks, see references/frameworks.md.

Show full SKILL.md (394 more words)Show less

Anti-patterns he pushes against

  • Baking Human Heuristics into AI: Relying on expert systems limits the AI to human-level creativity and prevents true generalization.
  • Move Fast and Break Things in AI: Breaking things in the real world with uniquely powerful technology causes irreversible damage; use the scientific method instead.
  • Assuming Transformers Are Enough: Believing that simply scaling LLMs will lead to AGI ignores the need for breakthroughs in continual learning and memory.
  • Viewing AI Merely as Consumer Apps: Focusing on chatbots and entertainment misses AI's true potential as a discovery engine for global scientific challenges.
  • Ignoring the Brain: Discarding neuroscience means missing out on the only working prototype of general intelligence and its hugely important insights.

For the full catalog with rationale and quotes, see references/anti-patterns.md.

Heuristics and rules of thumb

  • Target Root Node Problems: Focus efforts on foundational problems that automatically unlock entire new branches of research.
  • Use Games as Proving Grounds: Pick training environments that are challenging but offer easy data generation and clear metrics for progress.
  • Search In Silico, Validate In Vitro: Perform massive combinatorial searches virtually, and only move to the physical wet lab for final validation.
  • Immerse to Become Superpowered: Fully immerse yourself in the latest AI tools to leverage the capability overhang in your field.
  • Plan for Success Decades in Advance: Anticipate transformative consequences early and bake ethics and safety into the core of the project.

For the full list with attribution, see references/heuristics.md.

How to use this skill in conversation

When the user is discussing AI strategy, scientific discovery, or AGI timelines, channel Hassabis's rigorous, science-first mindset. Surface relevant frameworks by name (e.g., "Demis Hassabis suggests evaluating this using his Criteria for a Suitable AI Problem"). If the user is trying to solve a complex biological or physical problem, introduce the concept of "Digital Biology" or "Model-Guided Search."

Push back against reckless scaling or "move fast and break things" mentalities by citing the "Precautionary Principle for AGI." Always frame AI as a tool (a microscope or telescope) for understanding reality, rather than just a commercial product. Do not pretend to be Demis Hassabis; instead, apply his mental models to the user's specific context to elevate their strategic and scientific reasoning.

Generated with mimeo. If this material contributes to published work, please cite Kassis, T. (2026). "mimeo: Compiling Public Expert Corpora into Agent Skills and Testing What Transfers." arXiv:2609.00453.

© K-Dense-AI, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

SKILL.md and 9 other files (references) in output/demis-hassabis of K-Dense-AI/mimeo.

  • SKILL.md
  • AGENTS.md
  • avatar.png
  • references/anti-patterns.md
  • references/frameworks.md
  • references/heuristics.md
  • references/mental-models.md
  • references/principles.md
  • references/quotes.md
  • references/sources.md

Open the folder on GitHubat commit a4cea18

Used in 1 other repository

We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders. This page covers the copy in K-Dense-AI/mimeo, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Demis Hassabis next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

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Esmfold2JimLiu/science-skills2284 repos~2.5kAutomated safety check: PassApache-2.0
Alphafoldadaptyvbio/protein-design-skills1643 repos~1.2kAutomated safety check: PassMIT
Biopipelineslocbp-uzh/biopipelines109—~2.4kAutomated safety check: PassMIT
Chaiadaptyvbio/protein-design-skills1643 repos~1.5kAutomated safety check: PassMIT

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Works with

Questions about Demis Hassabis

What does Demis Hassabis do?

This skill channels the strategic and scientific reasoning of Demis Hassabis, CEO and co-founder of Google DeepMind, AlphaGo and AlphaFold, and 2024 Nobel Prize in Chemistry. Demis Hassabis is an agent skill from K-Dense-AI/mimeo. This skill channels the strategic and scientific reasoning of Demis Hassabis, CEO and co-founder of Google DeepMind, AlphaGo and AlphaFold, and 2024 Nobel Prize in Chemistry.

When should I use Demis Hassabis?

Demis Hassabis fits situations like: you are evaluating AI for scientific discovery; tackling root node problems; designing reinforcement learning systems; discussing AGI timelines.

How do I install Demis Hassabis in Claude Code?

Run `npx skills add K-Dense-AI/mimeo --skill demis-hassabis -a claude-code`. Or copy the skill folder (output/demis-hassabis in K-Dense-AI/mimeo) into .claude/skills/demis-hassabis in your project. Claude Code loads it when a task matches its description.

How do I install Demis Hassabis in Codex?

Run `npx skills add K-Dense-AI/mimeo --skill demis-hassabis -a codex`. Or copy the skill folder (output/demis-hassabis in K-Dense-AI/mimeo) into .agents/skills/demis-hassabis in your project. Codex loads it when a task matches its description.

Can I use Demis Hassabis in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add K-Dense-AI/mimeo --skill demis-hassabis -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/demis-hassabis, .gemini/skills/demis-hassabis, .github/skills/demis-hassabis and .opencode/skills/demis-hassabis in your project.

What does Demis Hassabis need to run?

SKILL.md names no scripts, command-line tools or credentials: Demis Hassabis is instructions for the agent only.

Does Demis Hassabis access the network?

SKILL.md names 1 domain. As links in the text: arxiv.org. This is read from the text; nothing was executed.

Is Demis Hassabis safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Demis Hassabis use?

Demis Hassabis is published under the MIT licence (the repository's licence). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Demis Hassabis use?

About 2k tokens (SKILL.md is roughly 7.9k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 6.3k tokens, read only when the agent opens those files.

What are the alternatives to Demis Hassabis?

Skills that share tags, products or a category with Demis Hassabis: Alphafold Database Fetch And Analyze (google-deepmind/science-skills, 3.2k stars), Esmfold2 (JimLiu/science-skills, 228 stars), Alphafold (adaptyvbio/protein-design-skills, 164 stars) and Biopipelines (locbp-uzh/biopipelines, 109 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Demis Hassabis?

K-Dense-AI (a GitHub organization) maintains it in K-Dense-AI/mimeo, which has 282 GitHub stars. The repository holds 21 skills in this directory. The repository was last updated on September 2, 2026.

Source: K-Dense-AI/mimeo on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.