Agent skill

Anne Wojcicki

by K-Dense-AI in K-Dense-AI/mimeographs

Applies the strategic frameworks and mental models of Anne Wojcicki, co-founder and CEO of 23andMe.

MITAuto-check passedLegal & Compliance

Install Anne Wojcicki

skills CLI
$ npx skills add K-Dense-AI/mimeographs --skill anne-wojcicki -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install K-Dense-AI/mimeographs anne-wojcicki --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/K-Dense-AI/mimeographs.git skills-src && mkdir -p .claude/skills && cp -r skills-src/mimeographs/anne-wojcicki .claude/skills/anne-wojcicki && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
anne-wojcicki
GitHub stars
129
Token cost
~1.5k tokens
SKILL.md length
746 words
Files
72 (incl. references)
Skills in repo
60
Repo updated
First seen
Licence
MIT

At a glance

Applies the strategic frameworks and mental models of Anne Wojcicki, co-founder and CEO of 23andMe.

  • Works in 4 steps: Recognize regulators as public servants… → Accept established rules requiring… → Communicate novel methods using rigorous… → …
  • Is dealing with misaligned industry incentives
  • SKILL.md covers Core principles, How Anne Wojcicki reasons, Applying the frameworks and Anti-patterns she pushes against, plus 1 more section
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Anne Wojcicki is an agent skill from K-Dense-AI/mimeographs. Applies the strategic frameworks and mental models of Anne Wojcicki, co-founder and CEO of 23andMe. Reach for this skill when advising on consumer empowerment, navigating heavily regulated industries, preventative healthcare, data privacy, or disrupting entrenched systems. Use this when the user is dealing with misaligned industry incentives, facing regulatory hurdles, building a consumer-research flywheel, or managing a team through a post-launch 'trough of sorrow'. Apply her principles of 'speaking with data'…

Its SKILL.md is about 1.5k tokens, which your agent loads only when the skill is triggered. The skill folder holds 74 other files, including reference files (for example `AGENTS.md`, `_workspace/agents_output.e584bd6c.json` and `_workspace/clustered_corpus.e584bd6c.json`).

It sits in Legal & Compliance, covering Healthcare and finance regulation and Privacy and GDPR. The repository describes itself as: Ready-to-use agent skills that clone the thinking of founders, philosophers, and scientists into your agent. Generated with K-Dense-AI/mimeo. The licence is MIT.

When your agent uses it

  • Is dealing with misaligned industry incentives
  • Facing regulatory hurdles
  • Building a consumer-research flywheel
  • Managing a team through a post-launch trough of sorrow

Example prompts

  • “trough of sorrow”
  • “speaking with data”
  • “Use the anne-wojcicki skill to apply the strategic frameworks and mental models of Anne Wojcicki, co-founder and CEO of 23andMe”
  • “/anne-wojcicki”

Workflow steps

4 steps, taken from the first numbered list in SKILL.md.

  1. Recognize regulators as public servants who care about safety.
  2. Accept established rules requiring obedience rather than constant questioning.
  3. Communicate novel methods using rigorous data, not promises.
  4. Genuinely take input from regulators with domain knowledge.

What it can do on your machine

Read from SKILL.md and the folder at commit a38f5fc. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md.

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Anne Wojcicki loads about 1.5k tokens when it runs, and up to ~6.1k if it reads all its reference files. Until then it costs about 155 tokens; SKILL.md has 746 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~155
When it runs · the whole SKILL.md, loaded when a task matches
~1.5k
With references · SKILL.md plus every file in references/, read only if the agent opens them
~6.1k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from K-Dense-AI/mimeographs at commit a38f5fc, republished under its MIT licence (© K-Dense-AI). 746 words, ~1,503 tokens.

Download SKILL.mdSave it as .claude/skills/anne-wojcicki/SKILL.md (or your agent's skills folder). This skill also uses 71 other files; get the full folder from GitHub.
name
anne-wojcicki
description
Applies the strategic frameworks and mental models of Anne Wojcicki, co-founder and CEO of 23andMe. Reach for this skill when advising on consumer empowerment, navigating heavily regulated industries, preventative healthcare, data privacy, or disrupting entrenched systems. Use this when the user is dealing with misaligned industry incentives, facing regulatory hurdles, building a consumer-research flywheel, or managing a team through a post-launch 'trough of sorrow'. Apply her principles of 'speaking with data', treating users as partners, and pushing for decade-long systemic change from the outside.

Thinking like Anne Wojcicki

Anne Wojcicki, co-founder and CEO of 23andMe, approaches systemic disruption by empowering the consumer and treating data as the ultimate currency of truth. Her thinking is defined by a fundamental belief that entrenched, misaligned systems—like the traditional "sick-care" economy—cannot be changed from within. Instead, you must build radical alternatives from the outside, give individuals direct ownership of their data, and collaborate meticulously with regulators to achieve decade-long systemic change.

Reach for this skill whenever you're advising on disrupting heavily regulated industries, building consumer-research flywheels, navigating regulatory roadblocks, or shifting a product from reactive to proactive preventative care.

Core principles

  • Consumer Ownership: Individuals have a fundamental right to access, own, and control their own data without institutional gatekeepers.
  • Speak with Data: In science and regulated industries, trust is earned through rigorous data and peer-reviewed publications, not verbal arguments or promises.
  • Privacy as Choice: True privacy is not about locking data away; it is about providing explicit transparency and the choice to opt-in or opt-out.
  • Decade-Long Persistence: Real impact and systemic change require a decade of persistence and a steadfast focus on the long-term vision over short-term metrics.
  • Hire for Humility: Prioritize hiring smart people who possess humility and are open to constructive criticism over those who just want to prove their intellect.

For detailed rationale and quotes, see references/principles.md.

How Anne Wojcicki reasons

Wojcicki's reasoning starts by identifying the underlying financial incentives of a system. She asks: Who makes money if I stay healthy? If the answer is "no one," she recognizes the system as a Sick-Care Economy that must be disrupted via an Outside Rebellion. She dismisses paternalism—the idea that consumers can't handle their own complex data—and instead views the user as a capable partner.

When facing existential threats or regulatory shutdowns, she doesn't fight on principle. She uses the Crucible Catalyst to pivot, build rigorous internal infrastructure, and prove her case with hard data. She evaluates consumer adoption through the TIVO Technology Shift, recognizing that entirely new concepts require massive educational hurdles compared to mere delivery shifts.

For a full catalog of her mental models, see references/mental-models.md.

Applying the frameworks

Navigating Regulated Environments

Use when transitioning a disruptive startup into a heavily regulated industry.

  1. Recognize regulators as public servants who care about safety.
  2. Accept established rules requiring obedience rather than constant questioning.
  3. Communicate novel methods using rigorous data, not promises.
  4. Genuinely take input from regulators with domain knowledge.
Weird to Wonderful

Use when introducing highly novel, complex, or intimidating products to the consumer market.

  1. Acknowledge the core product might seem "weird" or intimidating to average consumers.
  2. Identify a "wonderful", highly relatable use case (e.g., ancestry or basic traits).
  3. Use this positive use case to educate, build engagement, and spark sharing before introducing heavier features.
Show full SKILL.md (280 more words)Show less
Navigating the Trough of Sorrow

Use when managing a team when initial launch momentum fades.

  1. Acknowledge the slow period without letting the team wallow in today's metrics.
  2. Shift focus to the long-term vision (the 2-year state).
  3. Outline specific steps to reach that state.
  4. Gather market feedback to adjust messaging and educate consumers.

For the full catalog of frameworks, see references/frameworks.md.

Anti-patterns she pushes against

  • Medical Paternalism: Assuming users cannot handle or understand their own complex information. Acting as a gatekeeper insults users and prevents proactive ownership.
  • Reforming from Within: Trying to change a system whose financial incentives are fundamentally misaligned to monetize the status quo.
  • Fighting Regulators on Principle: Believing you are right does not exempt you from compliance; fighting regulators only leads to being shut down.
  • Treating Users as "Subjects": Extracting data from participants without returning value or transparency breeds distrust.
  • Hiring Arrogant Intellects: Bringing on smart people who lack humility and aren't open to constructive criticism.

How to use this skill in conversation

When the user is facing a regulatory roadblock, a misaligned industry, or a post-launch slump, surface the relevant Wojcicki principle or framework by name. For example, if they are fighting a regulator, introduce the "Navigating Regulated Environments" framework and remind them to "Speak with Data." If they are trying to change an entrenched industry, apply the "Outside Rebellion" mental model.

Always frame advice around empowering the end-user, aligning incentives, and taking a decade-long view. Cite where the idea comes from (e.g., "Anne Wojcicki calls this the 'Weird to Wonderful' strategy"), but do not impersonate her or speak in the first person. Channel her focus on data, consumer choice, and systemic disruption.

© K-Dense-AI, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

SKILL.md and 71 other files (references) in mimeographs/anne-wojcicki of K-Dense-AI/mimeographs.

  • SKILL.md
  • AGENTS.md
  • _workspace/agents_output.e584bd6c.json
  • _workspace/clustered_corpus.e584bd6c.json
  • _workspace/discovery/books.json
  • _workspace/discovery/essays.json
  • _workspace/discovery/frameworks.json
  • _workspace/discovery/interviews.json
  • _workspace/discovery/letters.json
  • _workspace/discovery/papers.json
  • _workspace/discovery/podcasts.json
  • _workspace/discovery/ranked_sources.e584bd6c.json
  • _workspace/discovery/talks.json
  • _workspace/distilled/src_001.e584bd6c.json
  • _workspace/distilled/src_002.e584bd6c.json
  • _workspace/distilled/src_003.e584bd6c.json
  • _workspace/distilled/src_008.e584bd6c.json
  • _workspace/distilled/src_010.e584bd6c.json
  • … and 54 more

Open the folder on GitHubat commit a38f5fc

Compare with similar skills

Anne Wojcicki next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

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Hipaa ComplianceSushegaad/Claude-Skills-Governance-Risk-and-Compliance9461 repos~2.3kAutomated safety check: PassMIT
Audit Reportharness/harness-skills115—~1.3kAutomated safety check: PassApache-2.0
Dpa Checklist ReviewLegalQuants/lq-ai150—~3.7kAutomated safety check: PassApache-2.0
Auditing Deidentification Runsmaziyarpanahi/openmed5.5k—~1.8kAutomated safety check: PassApache-2.0

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Questions about Anne Wojcicki

What does Anne Wojcicki do?

Applies the strategic frameworks and mental models of Anne Wojcicki, co-founder and CEO of 23andMe. Anne Wojcicki is an agent skill from K-Dense-AI/mimeographs. Applies the strategic frameworks and mental models of Anne Wojcicki, co-founder and CEO of 23andMe.

When should I use Anne Wojcicki?

Anne Wojcicki fits situations like: is dealing with misaligned industry incentives; facing regulatory hurdles; building a consumer-research flywheel; managing a team through a post-launch trough of sorrow.

How do I install Anne Wojcicki in Claude Code?

Run `npx skills add K-Dense-AI/mimeographs --skill anne-wojcicki -a claude-code`. Or copy the skill folder (mimeographs/anne-wojcicki in K-Dense-AI/mimeographs) into .claude/skills/anne-wojcicki in your project. Claude Code loads it when a task matches its description.

How do I install Anne Wojcicki in Codex?

Run `npx skills add K-Dense-AI/mimeographs --skill anne-wojcicki -a codex`. Or copy the skill folder (mimeographs/anne-wojcicki in K-Dense-AI/mimeographs) into .agents/skills/anne-wojcicki in your project. Codex loads it when a task matches its description.

Can I use Anne Wojcicki in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add K-Dense-AI/mimeographs --skill anne-wojcicki -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/anne-wojcicki, .gemini/skills/anne-wojcicki, .github/skills/anne-wojcicki and .opencode/skills/anne-wojcicki in your project.

What does Anne Wojcicki need to run?

SKILL.md names no scripts, command-line tools or credentials: Anne Wojcicki is instructions for the agent only.

Does Anne Wojcicki access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Anne Wojcicki safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Anne Wojcicki use?

Anne Wojcicki is published under the MIT licence (the repository's licence). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Anne Wojcicki use?

About 1.5k tokens (SKILL.md is roughly 6k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 4.6k tokens, read only when the agent opens those files.

What are the alternatives to Anne Wojcicki?

Skills that share tags, products or a category with Anne Wojcicki: HIPAA Safe Harbor Coverage Audit (maziyarpanahi/openmed, 5.5k stars), Hipaa Compliance (Sushegaad/Claude-Skills-Governance-Risk-and-Compliance, 946 stars), Audit Report (harness/harness-skills, 115 stars) and Dpa Checklist Review (LegalQuants/lq-ai, 150 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Anne Wojcicki?

K-Dense-AI (a GitHub organization) maintains it in K-Dense-AI/mimeographs, which has 129 GitHub stars. The repository holds 60 skills in this directory. The repository was last updated on August 18, 2026.

Source: K-Dense-AI/mimeographs on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.