Agent skill

Single Trajectory Analysis

by FreedomIntelligence in FreedomIntelligence/OpenClaw-Medical-Skills

Guide to reproducing OmicVerse trajectory workflows spanning PAGA, Palantir, VIA, velocity coupling, and fate scoring notebooks.

No licenceAuto-check passedData & Analytics

Install Single Trajectory Analysis

skills CLI
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill single-trajectory-analysis -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills single-trajectory-analysis --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/single-trajectory .claude/skills/single-trajectory-analysis && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
single-trajectory-analysis
GitHub stars
3.1k
Used in
1 other repo
Token cost
~1.1k tokens
SKILL.md length
481 words
Files
2
Skills in repo
279
Repo updated
First seen
Licence
None found

At a glance

Guide to reproducing OmicVerse trajectory workflows spanning PAGA, Palantir, VIA, velocity coupling, and fate scoring notebooks.

  • Works in 6 steps: Quality control: remove low-quality… → Normalization & log transformation… → Highly variable gene selection tailored… → …
  • Data & Analytics work in your project
  • SKILL.md covers Overview, Trajectory setup, Velocity coupling (VIA + scVelo) and Downstream fate scoring…, plus 4 more sections
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Single Trajectory Analysis is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Guide to reproducing OmicVerse trajectory workflows spanning PAGA, Palantir, VIA, velocity coupling, and fate scoring notebooks.

Its SKILL.md is about 1.1k tokens, which your agent loads only when the skill is triggered. The skill folder holds 1 other file (for example `reference.md`).

It sits in Data & Analytics. It works with Jupyter. The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.

When your agent uses it

  • Data & Analytics work in your project

Example prompts

  • “/single-trajectory-analysis”

Workflow steps

6 steps, taken from the first numbered list in SKILL.md.

  1. Quality control: remove low-quality cells/genes, apply doublet filtering.
  2. Normalization & log transformation (sc.pp.normalize_total, sc.pp.log1p).
  3. Highly variable gene selection tailored to immune datasets (sc.pp.highly_variable_genes).
  4. Batch correction if necessary (e.g., scvi-tools, bbknn).
  5. Compute PCA, neighbor graph, and embedding (UMAP/FA) used by all trajectory methods.
  6. For velocity: compute moments on the same neighbor graph before running VIA coupling.

What it can do on your machine

Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md.

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Single Trajectory Analysis loads about 1.1k tokens when it runs. Until then it costs about 39 tokens; SKILL.md has 481 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~39
When it runs · the whole SKILL.md, loaded when a task matches
~1.1k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 481 words (~1,101 tokens).

“This skill describes how to reproduce and extend the single-trajectory analysis workflow in omicverse, combining graph-based trajectory inference, RNA velocity coupling, and downstream fate scoring notebooks.”

— opening of SKILL.md by FreedomIntelligence
name
single-trajectory-analysis
title
Single-trajectory analysis

Read the full SKILL.md on GitHub

Files

SKILL.md and 1 other file in skills/single-trajectory of FreedomIntelligence/OpenClaw-Medical-Skills.

  • SKILL.md
  • reference.md

Open the folder on GitHubat commit b1f9b6e

Used in 1 other repository

We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in FreedomIntelligence/OpenClaw-Medical-Skills, which our catalogue first saw on October 9, 2026.

Compare with similar skills

Single Trajectory Analysis next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Single Trajectory Analysis compared with similar skills
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Single Trajectory Analysis this skillFreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repos~1.1kAutomated safety check: PassNone
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Migrate Glue Devendpoint To Interactive Sessionsaws-samples/aws-glue-samples1.5k—~3.6kAutomated safety check: PassMIT-0
Notebook For ExperimentJetBrains/intellij-community21k—~4.4kAutomated safety check: WarnCustom licence
Jupyter To Marimoericmjl/llamabot1832 repos~475Automated safety check: PassNone
Release Evidence WorkflowAli-Marandi/ClimateDataAnalyzer107—~1.6kAutomated safety check: PassMIT

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Works with

Questions about Single Trajectory Analysis

What does Single Trajectory Analysis do?

Guide to reproducing OmicVerse trajectory workflows spanning PAGA, Palantir, VIA, velocity coupling, and fate scoring notebooks. Single Trajectory Analysis is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Guide to reproducing OmicVerse trajectory workflows spanning PAGA, Palantir, VIA, velocity coupling, and fate scoring notebooks.

When should I use Single Trajectory Analysis?

Single Trajectory Analysis fits situations like: data & Analytics work in your project.

How do I install Single Trajectory Analysis in Claude Code?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill single-trajectory-analysis -a claude-code`. Or copy the skill folder (skills/single-trajectory in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/single-trajectory-analysis in your project. Claude Code loads it when a task matches its description.

How do I install Single Trajectory Analysis in Codex?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill single-trajectory-analysis -a codex`. Or copy the skill folder (skills/single-trajectory in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/single-trajectory-analysis in your project. Codex loads it when a task matches its description.

Can I use Single Trajectory Analysis in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill single-trajectory-analysis -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/single-trajectory-analysis, .gemini/skills/single-trajectory-analysis, .github/skills/single-trajectory-analysis and .opencode/skills/single-trajectory-analysis in your project.

What does Single Trajectory Analysis need to run?

SKILL.md names no scripts, command-line tools or credentials: Single Trajectory Analysis is instructions for the agent only.

Does Single Trajectory Analysis access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Single Trajectory Analysis safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Single Trajectory Analysis use?

No licence was found for Single Trajectory Analysis or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Single Trajectory Analysis use?

About 1.1k tokens (SKILL.md is roughly 4.4k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Single Trajectory Analysis?

Skills that share tags, products or a category with Single Trajectory Analysis: Jupyter Notebook (microsoft/ai-agents-for-beginners, 77k stars), Migrate Glue Devendpoint To Interactive Sessions (aws-samples/aws-glue-samples, 1.5k stars), Notebook For Experiment (JetBrains/intellij-community, 21k stars) and Jupyter To Marimo (ericmjl/llamabot, 183 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Single Trajectory Analysis?

FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,052 GitHub stars. The repository holds 279 skills in this directory. The repository was last updated on July 21, 2026.

Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.