Alphagenome Single Variant Analysis
google-deepmind/science-skills
Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API.
Agent skill
Bulk Rna Seq Deconvolution With Bulk2single
by FreedomIntelligence in FreedomIntelligence/OpenClaw-Medical-Skills
Turn bulk RNA-seq cohorts into synthetic single-cell datasets using omicverse's Bulk2Single workflow for cell fraction estimation, beta-VAE generation, and quality control comparisons against…
Install Bulk Rna Seq Deconvolution With Bulk2single
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bulk-rna-seq-deconvolution-with-bulk2single -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bulk-rna-seq-deconvolution-with-bulk2single --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bulk-to-single-deconvolution .claude/skills/bulk-rna-seq-deconvolution-with-bulk2single && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "bulk-rna-seq-deconvolution-with-bulk2single" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bulk-to-single-deconvolution into .claude/skills/bulk-rna-seq-deconvolution-with-bulk2single/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bulk-rna-seq-deconvolution-with-bulk2single", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bulk-to-single-deconvolutionType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bulk-rna-seq-deconvolution-with-bulk2single -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bulk-rna-seq-deconvolution-with-bulk2single --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .agents/skills && cp -r skills-src/skills/bulk-to-single-deconvolution .agents/skills/bulk-rna-seq-deconvolution-with-bulk2single && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "bulk-rna-seq-deconvolution-with-bulk2single" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bulk-to-single-deconvolution into .agents/skills/bulk-rna-seq-deconvolution-with-bulk2single/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bulk-rna-seq-deconvolution-with-bulk2single", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bulk-rna-seq-deconvolution-with-bulk2single -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bulk-rna-seq-deconvolution-with-bulk2single --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/skills/bulk-to-single-deconvolution .cursor/skills/bulk-rna-seq-deconvolution-with-bulk2single && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "bulk-rna-seq-deconvolution-with-bulk2single" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bulk-to-single-deconvolution into .cursor/skills/bulk-rna-seq-deconvolution-with-bulk2single/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bulk-rna-seq-deconvolution-with-bulk2single", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git --path skills/bulk-to-single-deconvolution--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bulk-rna-seq-deconvolution-with-bulk2single -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bulk-rna-seq-deconvolution-with-bulk2single --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/skills/bulk-to-single-deconvolution .gemini/skills/bulk-rna-seq-deconvolution-with-bulk2single && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "bulk-rna-seq-deconvolution-with-bulk2single" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bulk-to-single-deconvolution into .gemini/skills/bulk-rna-seq-deconvolution-with-bulk2single/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bulk-rna-seq-deconvolution-with-bulk2single", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bulk-rna-seq-deconvolution-with-bulk2singleInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bulk-rna-seq-deconvolution-with-bulk2single -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .github/skills && cp -r skills-src/skills/bulk-to-single-deconvolution .github/skills/bulk-rna-seq-deconvolution-with-bulk2single && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "bulk-rna-seq-deconvolution-with-bulk2single" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bulk-to-single-deconvolution into .github/skills/bulk-rna-seq-deconvolution-with-bulk2single/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bulk-rna-seq-deconvolution-with-bulk2single", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bulk-rna-seq-deconvolution-with-bulk2single -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bulk-rna-seq-deconvolution-with-bulk2single --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/skills/bulk-to-single-deconvolution .opencode/skills/bulk-rna-seq-deconvolution-with-bulk2single && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "bulk-rna-seq-deconvolution-with-bulk2single" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bulk-to-single-deconvolution into .opencode/skills/bulk-rna-seq-deconvolution-with-bulk2single/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bulk-rna-seq-deconvolution-with-bulk2single", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
Facts
- Skill name
bulk-rna-seq-deconvolution-with-bulk2single- GitHub stars
- 3.1k
- Used in
- 1 other repo
- Token cost
- ~1.1k tokens
- SKILL.md length
- 410 words
- Files
- 2
- Skills in repo
- 279
- Repo updated
- First seen
- Licence
- None found
At a glance
Turn bulk RNA-seq cohorts into synthetic single-cell datasets using omicverse's Bulk2Single workflow for cell fraction estimation, beta-VAE generation, and quality control comparisons against…
- Works in 8 steps: Load libraries and data → Initialise the Bulk2Single model → Estimate cell fractions → …
- Tasks that involve Bioinformatics
- SKILL.md covers Overview, Instructions, Examples and References
- Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md
What it does
Bulk Rna Seq Deconvolution With Bulk2single is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Turn bulk RNA-seq cohorts into synthetic single-cell datasets using omicverse's Bulk2Single workflow for cell fraction estimation, beta-VAE generation, and quality control comparisons against reference scRNA-seq.
Its SKILL.md is about 1.1k tokens, which your agent loads only when the skill is triggered. The skill folder holds 1 other file (for example `reference.md`).
It sits in Research & Science, covering Bioinformatics. The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.
When your agent uses it
- Tasks that involve Bioinformatics
Example prompts
- “/bulk-rna-seq-deconvolution-with-bulk2single”
Workflow steps
8 steps, taken from the first numbered list in SKILL.md.
- Load libraries and data
- Initialise the Bulk2Single model
- Estimate cell fractions
- Preprocess for beta-VAE
- Train or load the beta-VAE
- Generate and filter synthetic cells
- Benchmark against the reference atlas
- Troubleshooting tips
What it can do on your machine
Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.
Tool permissions
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Runs code
No scripts in the folder and no shell commands in SKILL.md.
From the folder's file list and the shell code blocks in SKILL.md.
Network
No URLs in SKILL.md.
From URLs in SKILL.md, links to its own repository left out.
Credentials
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
Context cost
Bulk Rna Seq Deconvolution With Bulk2single loads about 1.1k tokens when it runs. Until then it costs about 64 tokens; SKILL.md has 410 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
Safety
Auto-check passed
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.
SKILL.md
Without a licence we can't republish the file, so here is its outline and opening line. It has 410 words (~1,114 tokens).
“Use this skill when a user wants to reconstruct single-cell profiles from bulk RNA-seq together with a matched reference scRNA-seq atlas. It follows t_bulk2single.ipynb, which demonstrates how to harmonise PDAC bulk replicates, train the beta-VAE generator, and benchmark the output…”
- name
- bulk-rna-seq-deconvolution-with-bulk2single
- title
- Bulk RNA-seq deconvolution with Bulk2Single
Files
SKILL.md and 1 other file in skills/bulk-to-single-deconvolution of FreedomIntelligence/OpenClaw-Medical-Skills.
- SKILL.md
- reference.md
Open the folder on GitHubat commit b1f9b6e
Used in 1 other repository
We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in FreedomIntelligence/OpenClaw-Medical-Skills, which our catalogue first saw on October 9, 2026.
Compare with similar skills
Bulk Rna Seq Deconvolution With Bulk2single next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| Bulk Rna Seq Deconvolution With Bulk2single this skillFreedomIntelligence/OpenClaw-Medical-Skills | 3.1k | 1 repos | ~1.1k | Automated safety check: Pass | None | |
| Alphagenome Single Variant Analysisgoogle-deepmind/science-skills | 3.2k | 2 repos | ~3k | Automated safety check: Notes | Apache-2.0 | |
| 13C Metabolic Flux AnalysisK-Dense-AI/scientific-agent-skills | 48k | 1 repos | ~3.2k | Automated safety check: Pass | MIT | |
| Clinvar Databasegoogle-deepmind/science-skills | 3.2k | 2 repos | ~3.9k | Automated safety check: Notes | Apache-2.0 | |
| Metabolic Study Planneraiming-lab/AutoResearchClaw | 15k | — | ~1.9k | Automated safety check: Pass | MIT | |
| Dbsnp Databasegoogle-deepmind/science-skills | 3.2k | 2 repos | ~3.4k | Automated safety check: Notes | Apache-2.0 |
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Clinvar Database
google-deepmind/science-skills
A skill your agent uses when needing clinical significance, pathogenicity classifications (e.g., Pathogenic, Benign, VUS), clinical evidence rationales, or finding "hard positive" benchmark controls…
Metabolic Study Planner
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Turns a broad metabolic modelling topic into a concrete, paper-shaped plan with organism, model, perturbations, metrics and figures before any FBA code is written.
Dbsnp Database
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A skill your agent uses when you want to look up, map, and search for short genetic variants (SNPs, indels) in NCBI's dbSNP database.
MFA Pipeline Orchestrator
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Runs a metabolic flux analysis from model loading to phenotype prediction and figures by handing work to four sub-agents in sequence.
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Related
Categories
Questions about Bulk Rna Seq Deconvolution With Bulk2single
What does Bulk Rna Seq Deconvolution With Bulk2single do?
Turn bulk RNA-seq cohorts into synthetic single-cell datasets using omicverse's Bulk2Single workflow for cell fraction estimation, beta-VAE generation, and quality control comparisons against…. Bulk Rna Seq Deconvolution With Bulk2single is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Turn bulk RNA-seq cohorts into synthetic single-cell datasets using omicverse's Bulk2Single workflow for cell fraction estimation, beta-VAE generation, and quality control comparisons against reference scRNA-seq.
When should I use Bulk Rna Seq Deconvolution With Bulk2single?
Bulk Rna Seq Deconvolution With Bulk2single fits situations like: tasks that involve Bioinformatics.
How do I install Bulk Rna Seq Deconvolution With Bulk2single in Claude Code?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bulk-rna-seq-deconvolution-with-bulk2single -a claude-code`. Or copy the skill folder (skills/bulk-to-single-deconvolution in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/bulk-rna-seq-deconvolution-with-bulk2single in your project. Claude Code loads it when a task matches its description.
How do I install Bulk Rna Seq Deconvolution With Bulk2single in Codex?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bulk-rna-seq-deconvolution-with-bulk2single -a codex`. Or copy the skill folder (skills/bulk-to-single-deconvolution in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/bulk-rna-seq-deconvolution-with-bulk2single in your project. Codex loads it when a task matches its description.
Can I use Bulk Rna Seq Deconvolution With Bulk2single in Cursor, Gemini CLI or GitHub Copilot?
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bulk-rna-seq-deconvolution-with-bulk2single -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bulk-rna-seq-deconvolution-with-bulk2single, .gemini/skills/bulk-rna-seq-deconvolution-with-bulk2single, .github/skills/bulk-rna-seq-deconvolution-with-bulk2single and .opencode/skills/bulk-rna-seq-deconvolution-with-bulk2single in your project.
What does Bulk Rna Seq Deconvolution With Bulk2single need to run?
SKILL.md names no scripts, command-line tools or credentials: Bulk Rna Seq Deconvolution With Bulk2single is instructions for the agent only.
Does Bulk Rna Seq Deconvolution With Bulk2single access the network?
SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.
Is Bulk Rna Seq Deconvolution With Bulk2single safe to install?
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.
What licence does Bulk Rna Seq Deconvolution With Bulk2single use?
No licence was found for Bulk Rna Seq Deconvolution With Bulk2single or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.
How many tokens does Bulk Rna Seq Deconvolution With Bulk2single use?
About 1.1k tokens (SKILL.md is roughly 4.5k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.
What are the alternatives to Bulk Rna Seq Deconvolution With Bulk2single?
Skills that share tags, products or a category with Bulk Rna Seq Deconvolution With Bulk2single: Alphagenome Single Variant Analysis (google-deepmind/science-skills, 3.2k stars), 13C Metabolic Flux Analysis (K-Dense-AI/scientific-agent-skills, 48k stars), Clinvar Database (google-deepmind/science-skills, 3.2k stars) and Metabolic Study Planner (aiming-lab/AutoResearchClaw, 15k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
Who maintains Bulk Rna Seq Deconvolution With Bulk2single?
FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,053 GitHub stars. The repository holds 279 skills in this directory. The repository was last updated on July 21, 2026.
Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.