Bio Methylation Based Detection
GPTomics/bioSkills
Detects cancer and infers tissue-of-origin from cfDNA methylation by choosing conversion chemistry (bisulfite vs EM-seq vs TAPS vs cfMeDIP), calling read-level methylation haplotypes rather than…
Agent skill
Bio Methylation Based Detection
by FreedomIntelligence in FreedomIntelligence/OpenClaw-Medical-Skills
Analyzes cfDNA methylation patterns for cancer detection using cfMeDIP-seq or bisulfite sequencing with MethylDackel.
No licenceAuto-check passed
Install Bio Methylation Based Detection
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-methylation-based-detection -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-methylation-based-detection --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bio-methylation-based-detection .claude/skills/bio-methylation-based-detection && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "bio-methylation-based-detection" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-methylation-based-detection into .claude/skills/bio-methylation-based-detection/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-methylation-based-detection", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-methylation-based-detectionType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-methylation-based-detection -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-methylation-based-detection --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .agents/skills && cp -r skills-src/skills/bio-methylation-based-detection .agents/skills/bio-methylation-based-detection && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "bio-methylation-based-detection" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-methylation-based-detection into .agents/skills/bio-methylation-based-detection/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-methylation-based-detection", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-methylation-based-detection -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-methylation-based-detection --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/skills/bio-methylation-based-detection .cursor/skills/bio-methylation-based-detection && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "bio-methylation-based-detection" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-methylation-based-detection into .cursor/skills/bio-methylation-based-detection/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-methylation-based-detection", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git --path skills/bio-methylation-based-detection--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-methylation-based-detection -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-methylation-based-detection --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/skills/bio-methylation-based-detection .gemini/skills/bio-methylation-based-detection && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "bio-methylation-based-detection" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-methylation-based-detection into .gemini/skills/bio-methylation-based-detection/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-methylation-based-detection", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-methylation-based-detectionInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-methylation-based-detection -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .github/skills && cp -r skills-src/skills/bio-methylation-based-detection .github/skills/bio-methylation-based-detection && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "bio-methylation-based-detection" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-methylation-based-detection into .github/skills/bio-methylation-based-detection/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-methylation-based-detection", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-methylation-based-detection -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-methylation-based-detection --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/skills/bio-methylation-based-detection .opencode/skills/bio-methylation-based-detection && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "bio-methylation-based-detection" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-methylation-based-detection into .opencode/skills/bio-methylation-based-detection/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-methylation-based-detection", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
Facts
- Skill name
bio-methylation-based-detection- GitHub stars
- 3.1k
- Used in
- 1 other repo
- Token cost
- ~1.7k tokens
- SKILL.md length
- 219 words
- Files
- 3
- Skills in repo
- 170
- Repo updated
- First seen
- Licence
- None found
At a glance
Analyzes cfDNA methylation patterns for cancer detection using cfMeDIP-seq or bisulfite sequencing with MethylDackel.
- Using methylation biomarkers for early cancer detection
- SKILL.md covers Version Compatibility, Methods Overview, MethylDackel Pipeline and Python Implementation, plus 5 more sections
- Runs Python scripts from its folder; calls pip
- Minimal residual disease
What it does
Bio Methylation Based Detection is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Analyzes cfDNA methylation patterns for cancer detection using cfMeDIP-seq or bisulfite sequencing with MethylDackel. Identifies cancer-specific methylation signatures and performs tissue-of-origin deconvolution. Use when using methylation biomarkers for early cancer detection or minimal residual disease.
Its SKILL.md is about 1.7k tokens, which your agent loads only when the skill is triggered. The skill folder holds 3 other files (for example `examples/cfdna_methylation.py` and `usage-guide.md`).
The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.
When your agent uses it
- Using methylation biomarkers for early cancer detection
- Minimal residual disease
Example prompts
- “Use the bio-methylation-based-detection skill to analyz cfDNA methylation patterns for cancer detection using cfMeDIP-seq or bisulfite sequencing…”
- “/bio-methylation-based-detection”
Requirements
- Python 3
What it can do on your machine
Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.
Tool permissions
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Runs code
Ships script files (Python), which the agent can run.
Shell commands in SKILL.md call:
pip
From the folder's file list and the shell code blocks in SKILL.md.
Network
No URLs in SKILL.md. Its commands use pip, which can reach the network depending on how they are called.
From URLs in SKILL.md, links to its own repository left out.
Credentials
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
Context cost
Bio Methylation Based Detection loads about 1.7k tokens when it runs. Until then it costs about 85 tokens; SKILL.md has 219 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
Safety
Auto-check passed
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.
SKILL.md
Without a licence we can't republish the file, so here is its outline and opening line. It has 219 words (~1,746 tokens).
“Reference examples tested with: Bismark 0.24+, numpy 1.26+, pandas 2.2+, pysam 0.22+, scipy 1.12+, statsmodels 0.14+”
- name
- bio-methylation-based-detection
- tool_type
- python
- primary_tool
- MethylDackel
Files
SKILL.md and 2 other files in skills/bio-methylation-based-detection of FreedomIntelligence/OpenClaw-Medical-Skills.
- SKILL.md
- examples/cfdna_methylation.py
- usage-guide.md
Open the folder on GitHubat commit b1f9b6e
Used in 1 other repository
We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in FreedomIntelligence/OpenClaw-Medical-Skills, which our catalogue first saw on October 7, 2026.
Compare with similar skills
Bio Methylation Based Detection next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| Bio Methylation Based Detection this skillFreedomIntelligence/OpenClaw-Medical-Skills | 3.1k | 1 repos | ~1.7k | Automated safety check: Pass | None | |
| Bio Methylation Based DetectionGPTomics/bioSkills | 1.2k | 1 repos | ~4.1k | Automated safety check: Pass | MIT | |
| Bio Methylation Dmr DetectionGPTomics/bioSkills | 1.2k | 1 repos | ~6.1k | Automated safety check: Pass | MIT | |
| Bio Ribo Seq Orf DetectionGPTomics/bioSkills | 1.2k | 1 repos | ~3.1k | Automated safety check: Pass | MIT | |
| Bio Clip Seq Crosslink Site DetectionGPTomics/bioSkills | 1.2k | 2 repos | ~5k | Automated safety check: Pass | MIT | |
| Bio Methylation Dmr Detectionmajiayu000/claude-skill-registry | 666 | 2 repos | ~1.2k | Automated safety check: Pass | MIT |
Similar skills
Bio Methylation Dmr Detection
GPTomics/bioSkills
Detects differentially methylated regions (DMRs) from short-read bisulfite (WGBS/RRBS), array, and long-read methylation count tables using dmrseq (permutation region-FDR over the region selection)…
Bio Ribo Seq Orf Detection
GPTomics/bioSkills
Detect and quantify translated ORFs from Ribo-seq using 3-nucleotide periodicity, including uORFs, internal ORFs, dORFs, and novel ORFs.
Bio Clip Seq Crosslink Site Detection
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Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP T-to-C), or…
Bio Methylation Dmr Detection
majiayu000/claude-skill-registry
Differentially methylated region (DMR) detection using methylKit tiles, bsseq BSmooth, and DMRcate.
Bio Ribo Seq Orf Detection
majiayu000/claude-skill-registry
Detect and quantify translated ORFs from Ribo-seq data including uORFs and novel ORFs using RiboCode and ORFquant.
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Questions about Bio Methylation Based Detection
What does Bio Methylation Based Detection do?
Analyzes cfDNA methylation patterns for cancer detection using cfMeDIP-seq or bisulfite sequencing with MethylDackel. Bio Methylation Based Detection is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Analyzes cfDNA methylation patterns for cancer detection using cfMeDIP-seq or bisulfite sequencing with MethylDackel.
When should I use Bio Methylation Based Detection?
Bio Methylation Based Detection fits situations like: using methylation biomarkers for early cancer detection; minimal residual disease.
How do I install Bio Methylation Based Detection in Claude Code?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-methylation-based-detection -a claude-code`. Or copy the skill folder (skills/bio-methylation-based-detection in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/bio-methylation-based-detection in your project. Claude Code loads it when a task matches its description.
How do I install Bio Methylation Based Detection in Codex?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-methylation-based-detection -a codex`. Or copy the skill folder (skills/bio-methylation-based-detection in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/bio-methylation-based-detection in your project. Codex loads it when a task matches its description.
Can I use Bio Methylation Based Detection in Cursor, Gemini CLI or GitHub Copilot?
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-methylation-based-detection -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bio-methylation-based-detection, .gemini/skills/bio-methylation-based-detection, .github/skills/bio-methylation-based-detection and .opencode/skills/bio-methylation-based-detection in your project.
What does Bio Methylation Based Detection need to run?
Going by SKILL.md and its folder, Bio Methylation Based Detection needs Python for the scripts in its folder and the command-line tools its instructions call (pip). Our summary lists: Python 3.
Does Bio Methylation Based Detection access the network?
SKILL.md contains no URLs. Its commands use pip, which can reach the network depending on how they are called. This is read from the text; nothing was executed.
Is Bio Methylation Based Detection safe to install?
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.
What licence does Bio Methylation Based Detection use?
No licence was found for Bio Methylation Based Detection or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.
How many tokens does Bio Methylation Based Detection use?
About 1.7k tokens (SKILL.md is roughly 7k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.
What are the alternatives to Bio Methylation Based Detection?
Skills that share tags, products or a category with Bio Methylation Based Detection: Bio Methylation Based Detection (GPTomics/bioSkills, 1.2k stars), Bio Methylation Dmr Detection (GPTomics/bioSkills, 1.2k stars), Bio Ribo Seq Orf Detection (GPTomics/bioSkills, 1.2k stars) and Bio Clip Seq Crosslink Site Detection (GPTomics/bioSkills, 1.2k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
Who maintains Bio Methylation Based Detection?
FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,052 GitHub stars. The repository holds 170 skills in this directory. The repository was last updated on July 21, 2026.
Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.