Hypothesis Generation
spacering-net/codeg
Structured hypothesis formulation from observations. An agent skill from spacering-net/codeg.
Agent skill
Bio Isoform Switching
by FreedomIntelligence in FreedomIntelligence/OpenClaw-Medical-Skills
Analyzes isoform switching events and functional consequences using IsoformSwitchAnalyzeR.
Install Bio Isoform Switching
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-isoform-switching -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-isoform-switching --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bio-isoform-switching .claude/skills/bio-isoform-switching && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "bio-isoform-switching" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-isoform-switching into .claude/skills/bio-isoform-switching/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-isoform-switching", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-isoform-switchingType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-isoform-switching -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-isoform-switching --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .agents/skills && cp -r skills-src/skills/bio-isoform-switching .agents/skills/bio-isoform-switching && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "bio-isoform-switching" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-isoform-switching into .agents/skills/bio-isoform-switching/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-isoform-switching", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-isoform-switching -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-isoform-switching --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/skills/bio-isoform-switching .cursor/skills/bio-isoform-switching && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "bio-isoform-switching" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-isoform-switching into .cursor/skills/bio-isoform-switching/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-isoform-switching", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git --path skills/bio-isoform-switching--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-isoform-switching -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-isoform-switching --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/skills/bio-isoform-switching .gemini/skills/bio-isoform-switching && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "bio-isoform-switching" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-isoform-switching into .gemini/skills/bio-isoform-switching/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-isoform-switching", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-isoform-switchingInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-isoform-switching -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .github/skills && cp -r skills-src/skills/bio-isoform-switching .github/skills/bio-isoform-switching && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "bio-isoform-switching" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-isoform-switching into .github/skills/bio-isoform-switching/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-isoform-switching", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-isoform-switching -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-isoform-switching --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/skills/bio-isoform-switching .opencode/skills/bio-isoform-switching && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "bio-isoform-switching" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-isoform-switching into .opencode/skills/bio-isoform-switching/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-isoform-switching", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
Facts
- Skill name
bio-isoform-switching- GitHub stars
- 3.1k
- Token cost
- ~1.5k tokens
- SKILL.md length
- 276 words
- Files
- 3
- Skills in repo
- 279
- Repo updated
- First seen
- Licence
- None found
At a glance
Analyzes isoform switching events and functional consequences using IsoformSwitchAnalyzeR.
- Investigating how splicing changes affect protein function
- SKILL.md covers Version Compatibility, IsoformSwitchAnalyzeR Workflow, Functional Annotation and Consequence Analysis, plus 4 more sections
- Runs R scripts from its folder
What it does
Bio Isoform Switching is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Analyzes isoform switching events and functional consequences using IsoformSwitchAnalyzeR. Predicts protein domain changes, NMD sensitivity, ORF alterations, and coding potential shifts between conditions. Use when investigating how splicing changes affect protein function.
Its SKILL.md is about 1.5k tokens, which your agent loads only when the skill is triggered. The skill folder holds 3 other files (for example `usage-guide.md`).
It sits in Research & Science. The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.
When your agent uses it
- Investigating how splicing changes affect protein function
Example prompts
- “Use the bio-isoform-switching skill to analyz isoform switching events and functional consequences using IsoformSwitchAnalyzeR”
- “/bio-isoform-switching”
What it can do on your machine
Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.
Tool permissions
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Runs code
Ships script files (R), which the agent can run.
From the folder's file list and the shell code blocks in SKILL.md.
Network
No URLs in SKILL.md.
From URLs in SKILL.md, links to its own repository left out.
Credentials
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
Context cost
Bio Isoform Switching loads about 1.5k tokens when it runs. Until then it costs about 74 tokens; SKILL.md has 276 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
Safety
Auto-check passed
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.
SKILL.md
Without a licence we can't republish the file, so here is its outline and opening line. It has 276 words (~1,459 tokens).
“Reference examples tested with: Salmon 1.10+”
- name
- bio-isoform-switching
- tool_type
- r
- primary_tool
- IsoformSwitchAnalyzeR
Files
SKILL.md and 2 other files in skills/bio-isoform-switching of FreedomIntelligence/OpenClaw-Medical-Skills.
- SKILL.md
- examples/isoform_switch_analysis.R
- usage-guide.md
Open the folder on GitHubat commit b1f9b6e
Compare with similar skills
Bio Isoform Switching next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| Bio Isoform Switching this skillFreedomIntelligence/OpenClaw-Medical-Skills | 3.1k | — | ~1.5k | Automated safety check: Pass | None | |
| Hypothesis Generationspacering-net/codeg | 3.9k | 14 repos | ~3.6k | Automated safety check: Notes | MIT | |
| GitHub Deep Researchbytedance/deer-flow | 84k | 4 repos | ~1.3k | Automated safety check: Pass | MIT | |
| Nature Paper CardYuan1z0825/nature-skills | 47k | 2 repos | ~2.1k | Automated safety check: Pass | Apache-2.0 | |
| Content Research Writerweapp-tailwindcss/weapp-tailwindcss | 1.9k | 25 repos | ~3.5k | Automated safety check: Pass | MIT | |
| Peer Reviewspacering-net/codeg | 3.9k | 17 repos | ~5.9k | Automated safety check: Notes | MIT |
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GitHub Deep Research
bytedance/deer-flow
Researches a GitHub repository over four rounds using the GitHub API and web search, then writes a structured markdown report with timeline, metrics and Mermaid diagrams.
Nature Paper Card
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Builds a structured deep-reading card for one scientific paper, covering methods, how experiments support claims, limitations and research ideas, with a script to prepare the source.
Content Research Writer
weapp-tailwindcss/weapp-tailwindcss
Assists in writing high-quality content by conducting research, adding citations, improving hooks, iterating on outlines, and providing real-time feedback on each section.
Peer Review
spacering-net/codeg
Structured manuscript/grant review with checklist-based evaluation.
Last30days
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Research what people actually say about any topic in the last 30 days.
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Categories
Questions about Bio Isoform Switching
What does Bio Isoform Switching do?
Analyzes isoform switching events and functional consequences using IsoformSwitchAnalyzeR. Bio Isoform Switching is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Analyzes isoform switching events and functional consequences using IsoformSwitchAnalyzeR.
When should I use Bio Isoform Switching?
Bio Isoform Switching fits situations like: investigating how splicing changes affect protein function.
How do I install Bio Isoform Switching in Claude Code?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-isoform-switching -a claude-code`. Or copy the skill folder (skills/bio-isoform-switching in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/bio-isoform-switching in your project. Claude Code loads it when a task matches its description.
How do I install Bio Isoform Switching in Codex?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-isoform-switching -a codex`. Or copy the skill folder (skills/bio-isoform-switching in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/bio-isoform-switching in your project. Codex loads it when a task matches its description.
Can I use Bio Isoform Switching in Cursor, Gemini CLI or GitHub Copilot?
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-isoform-switching -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bio-isoform-switching, .gemini/skills/bio-isoform-switching, .github/skills/bio-isoform-switching and .opencode/skills/bio-isoform-switching in your project.
What does Bio Isoform Switching need to run?
Going by SKILL.md and its folder, Bio Isoform Switching needs R for the scripts in its folder.
Does Bio Isoform Switching access the network?
SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.
Is Bio Isoform Switching safe to install?
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.
What licence does Bio Isoform Switching use?
No licence was found for Bio Isoform Switching or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.
How many tokens does Bio Isoform Switching use?
About 1.5k tokens (SKILL.md is roughly 5.8k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.
What are the alternatives to Bio Isoform Switching?
Skills that share tags, products or a category with Bio Isoform Switching: Hypothesis Generation (spacering-net/codeg, 3.9k stars), GitHub Deep Research (bytedance/deer-flow, 84k stars), Nature Paper Card (Yuan1z0825/nature-skills, 47k stars) and Content Research Writer (weapp-tailwindcss/weapp-tailwindcss, 1.9k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
Who maintains Bio Isoform Switching?
FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,052 GitHub stars. The repository holds 279 skills in this directory. The repository was last updated on July 21, 2026.
Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.