Agent skill

Bio Hi C Analysis Loop Calling

by FreedomIntelligence in FreedomIntelligence/OpenClaw-Medical-Skills

Detect chromatin loops and point interactions from Hi-C data using cooltools, chromosight, and HiCCUPS-like methods.

No licenceAuto-check passedData & Analytics

Install Bio Hi C Analysis Loop Calling

skills CLI
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-hi-c-analysis-loop-calling -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-hi-c-analysis-loop-calling --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bio-hi-c-analysis-loop-calling .claude/skills/bio-hi-c-analysis-loop-calling && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
bio-hi-c-analysis-loop-calling
GitHub stars
3.1k
Used in
1 other repo
Token cost
~2.1k tokens
SKILL.md length
225 words
Files
3
Skills in repo
170
Repo updated
First seen
Licence
None found

At a glance

Detect chromatin loops and point interactions from Hi-C data using cooltools, chromosight, and HiCCUPS-like methods.

  • Detecting chromatin loops from Hi-C data
  • SKILL.md covers Version Compatibility, Required Imports, Call Loops with cooltools (Dot… and Using chromosight (CLI), plus 11 more sections
  • Runs Python scripts from its folder; calls pip

What it does

Bio Hi C Analysis Loop Calling is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Detect chromatin loops and point interactions from Hi-C data using cooltools, chromosight, and HiCCUPS-like methods. Identify CTCF-mediated loops and enhancer-promoter contacts. Use when detecting chromatin loops from Hi-C data.

Its SKILL.md is about 2.1k tokens, which your agent loads only when the skill is triggered. The skill folder holds 3 other files (for example `examples/call_loops.py` and `usage-guide.md`).

It sits in Data & Analytics. The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.

When your agent uses it

  • Detecting chromatin loops from Hi-C data

Example prompts

  • “/bio-hi-c-analysis-loop-calling”

Requirements

  • Python 3

What it can do on your machine

Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships script files (Python), which the agent can run.

    Shell commands in SKILL.md call:

    • pip

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md. Its commands use pip, which can reach the network depending on how they are called.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Bio Hi C Analysis Loop Calling loads about 2.1k tokens when it runs. Until then it costs about 65 tokens; SKILL.md has 225 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~65
When it runs · the whole SKILL.md, loaded when a task matches
~2.1k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 225 words (~2,119 tokens).

“Reference examples tested with: bedtools 2.31+, cooler 0.9+, cooltools 0.6+, matplotlib 3.8+, numpy 1.26+, pandas 2.2+, pybedtools 0.9+”

— opening of SKILL.md by FreedomIntelligence
name
bio-hi-c-analysis-loop-calling
tool_type
mixed
primary_tool
cooltools

Read the full SKILL.md on GitHub

Files

SKILL.md and 2 other files in skills/bio-hi-c-analysis-loop-calling of FreedomIntelligence/OpenClaw-Medical-Skills.

  • SKILL.md
  • examples/call_loops.py
  • usage-guide.md

Open the folder on GitHubat commit b1f9b6e

Used in 1 other repository

We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in FreedomIntelligence/OpenClaw-Medical-Skills, which our catalogue first saw on October 7, 2026.

Compare with similar skills

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TimesFM Forecastinggoogle-research/timesfm34k—~4.7kAutomated safety check: PassApache-2.0

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Questions about Bio Hi C Analysis Loop Calling

What does Bio Hi C Analysis Loop Calling do?

Detect chromatin loops and point interactions from Hi-C data using cooltools, chromosight, and HiCCUPS-like methods. Bio Hi C Analysis Loop Calling is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Detect chromatin loops and point interactions from Hi-C data using cooltools, chromosight, and HiCCUPS-like methods.

When should I use Bio Hi C Analysis Loop Calling?

Bio Hi C Analysis Loop Calling fits situations like: detecting chromatin loops from Hi-C data.

How do I install Bio Hi C Analysis Loop Calling in Claude Code?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-hi-c-analysis-loop-calling -a claude-code`. Or copy the skill folder (skills/bio-hi-c-analysis-loop-calling in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/bio-hi-c-analysis-loop-calling in your project. Claude Code loads it when a task matches its description.

How do I install Bio Hi C Analysis Loop Calling in Codex?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-hi-c-analysis-loop-calling -a codex`. Or copy the skill folder (skills/bio-hi-c-analysis-loop-calling in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/bio-hi-c-analysis-loop-calling in your project. Codex loads it when a task matches its description.

Can I use Bio Hi C Analysis Loop Calling in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-hi-c-analysis-loop-calling -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bio-hi-c-analysis-loop-calling, .gemini/skills/bio-hi-c-analysis-loop-calling, .github/skills/bio-hi-c-analysis-loop-calling and .opencode/skills/bio-hi-c-analysis-loop-calling in your project.

What does Bio Hi C Analysis Loop Calling need to run?

Going by SKILL.md and its folder, Bio Hi C Analysis Loop Calling needs Python for the scripts in its folder and the command-line tools its instructions call (pip). Our summary lists: Python 3.

Does Bio Hi C Analysis Loop Calling access the network?

SKILL.md contains no URLs. Its commands use pip, which can reach the network depending on how they are called. This is read from the text; nothing was executed.

Is Bio Hi C Analysis Loop Calling safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Bio Hi C Analysis Loop Calling use?

No licence was found for Bio Hi C Analysis Loop Calling or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Bio Hi C Analysis Loop Calling use?

About 2.1k tokens (SKILL.md is roughly 8.5k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Bio Hi C Analysis Loop Calling?

Skills that share tags, products or a category with Bio Hi C Analysis Loop Calling: Exploratory Data Analysis (spacering-net/codeg, 3.8k stars), Matplotlib (zLanqing/codex-claude-academic-skills, 4.6k stars), Scikit Learn (zLanqing/codex-claude-academic-skills, 4.6k stars) and Chart Visualization (bytedance/deer-flow, 83k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Bio Hi C Analysis Loop Calling?

FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,052 GitHub stars. The repository holds 170 skills in this directory. The repository was last updated on July 21, 2026.

Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.