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Agent skill

Bio Genome Engineering Base Editing Design

by FreedomIntelligence in FreedomIntelligence/OpenClaw-Medical-Skills

Design guides for cytosine and adenine base editing using editing window optimization and BE-Hive outcome prediction.

No licenceAuto-check passedResearch & Science

Install Bio Genome Engineering Base Editing Design

skills CLI
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-genome-engineering-base-editing-design -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-genome-engineering-base-editing-design --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bio-genome-engineering-base-editing-design .claude/skills/bio-genome-engineering-base-editing-design && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
bio-genome-engineering-base-editing-design
GitHub stars
3.1k
Used in
1 other repo
Token cost
~2.3k tokens
SKILL.md length
197 words
Files
3
Skills in repo
279
Repo updated
First seen
Licence
None found

At a glance

Design guides for cytosine and adenine base editing using editing window optimization and BE-Hive outcome prediction.

  • Designing base editor experiments for precise nucleotide changes
  • SKILL.md covers Version Compatibility, Base Editor Types, Find Editable Positions and Editing Efficiency by Position, plus 4 more sections
  • Runs Python scripts from its folder; calls pip
  • Tasks that involve Bioinformatics

What it does

Bio Genome Engineering Base Editing Design is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Design guides for cytosine and adenine base editing using editing window optimization and BE-Hive outcome prediction. Select optimal positions for C-to-T or A-to-G conversions without double-strand breaks. Use when designing base editor experiments for precise nucleotide changes.

Its SKILL.md is about 2.3k tokens, which your agent loads only when the skill is triggered. The skill folder holds 3 other files (for example `examples/base_editing_design.py` and `usage-guide.md`).

It sits in Research & Science, covering Bioinformatics. The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.

When your agent uses it

  • Designing base editor experiments for precise nucleotide changes
  • Tasks that involve Bioinformatics

Example prompts

  • “/bio-genome-engineering-base-editing-design”

Requirements

  • Python 3

What it can do on your machine

Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships script files (Python), which the agent can run.

    Shell commands in SKILL.md call:

    • pip

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md. Its commands use pip, which can reach the network depending on how they are called.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Bio Genome Engineering Base Editing Design loads about 2.3k tokens when it runs. Until then it costs about 81 tokens; SKILL.md has 197 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~81
When it runs · the whole SKILL.md, loaded when a task matches
~2.3k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 197 words (~2,276 tokens).

“Reference examples tested with: BioPython 1.83+”

— opening of SKILL.md by FreedomIntelligence
name
bio-genome-engineering-base-editing-design
tool_type
python
primary_tool
BE-Hive

Read the full SKILL.md on GitHub

Files

SKILL.md and 2 other files in skills/bio-genome-engineering-base-editing-design of FreedomIntelligence/OpenClaw-Medical-Skills.

  • SKILL.md
  • examples/base_editing_design.py
  • usage-guide.md

Open the folder on GitHubat commit b1f9b6e

Used in 1 other repository

We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in FreedomIntelligence/OpenClaw-Medical-Skills, which our catalogue first saw on October 7, 2026.

Compare with similar skills

Bio Genome Engineering Base Editing Design next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Bio Genome Engineering Base Editing Design compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Bio Genome Engineering Base Editing Design this skillFreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repos~2.3kAutomated safety check: PassNone
Alphagenome Single Variant Analysisgoogle-deepmind/science-skills3.2k2 repos~3kAutomated safety check: NotesApache-2.0
13C Metabolic Flux AnalysisK-Dense-AI/scientific-agent-skills48k1 repos~3.2kAutomated safety check: PassMIT
Clinvar Databasegoogle-deepmind/science-skills3.2k2 repos~3.9kAutomated safety check: NotesApache-2.0
Metabolic Study Planneraiming-lab/AutoResearchClaw15k—~1.9kAutomated safety check: PassMIT
Dbsnp Databasegoogle-deepmind/science-skills3.2k2 repos~3.4kAutomated safety check: NotesApache-2.0

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Categories

Questions about Bio Genome Engineering Base Editing Design

What does Bio Genome Engineering Base Editing Design do?

Design guides for cytosine and adenine base editing using editing window optimization and BE-Hive outcome prediction. Bio Genome Engineering Base Editing Design is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Design guides for cytosine and adenine base editing using editing window optimization and BE-Hive outcome prediction.

When should I use Bio Genome Engineering Base Editing Design?

Bio Genome Engineering Base Editing Design fits situations like: designing base editor experiments for precise nucleotide changes; tasks that involve Bioinformatics.

How do I install Bio Genome Engineering Base Editing Design in Claude Code?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-genome-engineering-base-editing-design -a claude-code`. Or copy the skill folder (skills/bio-genome-engineering-base-editing-design in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/bio-genome-engineering-base-editing-design in your project. Claude Code loads it when a task matches its description.

How do I install Bio Genome Engineering Base Editing Design in Codex?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-genome-engineering-base-editing-design -a codex`. Or copy the skill folder (skills/bio-genome-engineering-base-editing-design in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/bio-genome-engineering-base-editing-design in your project. Codex loads it when a task matches its description.

Can I use Bio Genome Engineering Base Editing Design in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-genome-engineering-base-editing-design -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bio-genome-engineering-base-editing-design, .gemini/skills/bio-genome-engineering-base-editing-design, .github/skills/bio-genome-engineering-base-editing-design and .opencode/skills/bio-genome-engineering-base-editing-design in your project.

What does Bio Genome Engineering Base Editing Design need to run?

Going by SKILL.md and its folder, Bio Genome Engineering Base Editing Design needs Python for the scripts in its folder and the command-line tools its instructions call (pip). Our summary lists: Python 3.

Does Bio Genome Engineering Base Editing Design access the network?

SKILL.md contains no URLs. Its commands use pip, which can reach the network depending on how they are called. This is read from the text; nothing was executed.

Is Bio Genome Engineering Base Editing Design safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Bio Genome Engineering Base Editing Design use?

No licence was found for Bio Genome Engineering Base Editing Design or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Bio Genome Engineering Base Editing Design use?

About 2.3k tokens (SKILL.md is roughly 9.1k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Bio Genome Engineering Base Editing Design?

Skills that share tags, products or a category with Bio Genome Engineering Base Editing Design: Alphagenome Single Variant Analysis (google-deepmind/science-skills, 3.2k stars), 13C Metabolic Flux Analysis (K-Dense-AI/scientific-agent-skills, 48k stars), Clinvar Database (google-deepmind/science-skills, 3.2k stars) and Metabolic Study Planner (aiming-lab/AutoResearchClaw, 15k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Bio Genome Engineering Base Editing Design?

FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,052 GitHub stars. The repository holds 279 skills in this directory. The repository was last updated on July 21, 2026.

Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.