MCP Server Builder
anthropics/skills
Guides the design and implementation of Model Context Protocol servers in TypeScript or Python, from tool naming and error messages to evaluation.
Agent skill
Bio Differential Splicing
by FreedomIntelligence in FreedomIntelligence/OpenClaw-Medical-Skills
Detects differential alternative splicing between conditions using rMATS-turbo (BAM-based) or SUPPA2 diffSplice (TPM-based).
No licenceAuto-check passed
Install Bio Differential Splicing
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-differential-splicing -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-differential-splicing --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bio-differential-splicing .claude/skills/bio-differential-splicing && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "bio-differential-splicing" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-differential-splicing into .claude/skills/bio-differential-splicing/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-differential-splicing", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-differential-splicingType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-differential-splicing -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-differential-splicing --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .agents/skills && cp -r skills-src/skills/bio-differential-splicing .agents/skills/bio-differential-splicing && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "bio-differential-splicing" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-differential-splicing into .agents/skills/bio-differential-splicing/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-differential-splicing", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-differential-splicing -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-differential-splicing --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/skills/bio-differential-splicing .cursor/skills/bio-differential-splicing && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "bio-differential-splicing" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-differential-splicing into .cursor/skills/bio-differential-splicing/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-differential-splicing", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git --path skills/bio-differential-splicing--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-differential-splicing -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-differential-splicing --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/skills/bio-differential-splicing .gemini/skills/bio-differential-splicing && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "bio-differential-splicing" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-differential-splicing into .gemini/skills/bio-differential-splicing/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-differential-splicing", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-differential-splicingInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-differential-splicing -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .github/skills && cp -r skills-src/skills/bio-differential-splicing .github/skills/bio-differential-splicing && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "bio-differential-splicing" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-differential-splicing into .github/skills/bio-differential-splicing/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-differential-splicing", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-differential-splicing -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-differential-splicing --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/skills/bio-differential-splicing .opencode/skills/bio-differential-splicing && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "bio-differential-splicing" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-differential-splicing into .opencode/skills/bio-differential-splicing/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-differential-splicing", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
Facts
- Skill name
bio-differential-splicing- GitHub stars
- 3.1k
- Token cost
- ~1.5k tokens
- SKILL.md length
- 289 words
- Files
- 4
- Skills in repo
- 170
- Repo updated
- First seen
- Licence
- None found
At a glance
Detects differential alternative splicing between conditions using rMATS-turbo (BAM-based) or SUPPA2 diffSplice (TPM-based).
- Comparing splicing patterns between treatment groups
- SKILL.md covers Version Compatibility, Tool Comparison, rMATS-turbo Analysis and SUPPA2 Differential Analysis, plus 4 more sections
- Runs R and Shell scripts from its folder; calls pip
What it does
Bio Differential Splicing is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Detects differential alternative splicing between conditions using rMATS-turbo (BAM-based) or SUPPA2 diffSplice (TPM-based). Reports events with FDR-corrected significance and delta PSI effect sizes. Use when comparing splicing patterns between treatment groups, tissues, or disease states.
Its SKILL.md is about 1.5k tokens, which your agent loads only when the skill is triggered. The skill folder holds 4 other files (for example `examples/diff_splicing_rmats.sh` and `usage-guide.md`).
It works with Python. The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.
When your agent uses it
- Comparing splicing patterns between treatment groups
Example prompts
- “Use the bio-differential-splicing skill to detect differential alternative splicing between conditions using rMATS-turbo (BAM-based) or SUPPA2…”
- “/bio-differential-splicing”
Requirements
- Python 3
- A Bash shell
What it can do on your machine
Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.
Tool permissions
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Runs code
Ships script files (R and Shell), which the agent can run.
Shell commands in SKILL.md call:
pip
From the folder's file list and the shell code blocks in SKILL.md.
Network
No URLs in SKILL.md. Its commands use pip, which can reach the network depending on how they are called.
From URLs in SKILL.md, links to its own repository left out.
Credentials
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
Context cost
Bio Differential Splicing loads about 1.5k tokens when it runs. Until then it costs about 79 tokens; SKILL.md has 289 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
Safety
Auto-check passed
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.
SKILL.md
Without a licence we can't republish the file, so here is its outline and opening line. It has 289 words (~1,504 tokens).
“Reference examples tested with: STAR 2.7.11+, pandas 2.2+”
- name
- bio-differential-splicing
- tool_type
- mixed
- primary_tool
- rMATS-turbo
Files
SKILL.md and 3 other files in skills/bio-differential-splicing of FreedomIntelligence/OpenClaw-Medical-Skills.
- SKILL.md
- examples/diff_splicing_leafcutter.R
- examples/diff_splicing_rmats.sh
- usage-guide.md
Open the folder on GitHubat commit b1f9b6e
Compare with similar skills
Bio Differential Splicing next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| Bio Differential Splicing this skillFreedomIntelligence/OpenClaw-Medical-Skills | 3.1k | — | ~1.5k | Automated safety check: Pass | None | |
| MCP Server Builderanthropics/skills | 180k | 64 repos | ~2.3k | Automated safety check: Pass | Apache-2.0 | |
| PDF Processinganthropics/skills | 180k | 48 repos | ~2k | Automated safety check: Pass | Proprietary | |
| NotebookLM Research AssistantPleasePrompto/notebooklm-skill | 7.8k | 14 repos | ~2.4k | Automated safety check: Notes | MIT | |
| Manim Video Productionbrowser-use/video-use | 28k | 6 repos | ~3k | Automated safety check: Pass | MIT | |
| Code Review ChecklistshareAI-lab/learn-claude-code | 78k | 5 repos | ~1.1k | Automated safety check: Pass | MIT |
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Related
Works with
Questions about Bio Differential Splicing
What does Bio Differential Splicing do?
Detects differential alternative splicing between conditions using rMATS-turbo (BAM-based) or SUPPA2 diffSplice (TPM-based). Bio Differential Splicing is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Detects differential alternative splicing between conditions using rMATS-turbo (BAM-based) or SUPPA2 diffSplice (TPM-based).
When should I use Bio Differential Splicing?
Bio Differential Splicing fits situations like: comparing splicing patterns between treatment groups.
How do I install Bio Differential Splicing in Claude Code?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-differential-splicing -a claude-code`. Or copy the skill folder (skills/bio-differential-splicing in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/bio-differential-splicing in your project. Claude Code loads it when a task matches its description.
How do I install Bio Differential Splicing in Codex?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-differential-splicing -a codex`. Or copy the skill folder (skills/bio-differential-splicing in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/bio-differential-splicing in your project. Codex loads it when a task matches its description.
Can I use Bio Differential Splicing in Cursor, Gemini CLI or GitHub Copilot?
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-differential-splicing -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bio-differential-splicing, .gemini/skills/bio-differential-splicing, .github/skills/bio-differential-splicing and .opencode/skills/bio-differential-splicing in your project.
What does Bio Differential Splicing need to run?
Going by SKILL.md and its folder, Bio Differential Splicing needs R and a shell for the scripts in its folder and the command-line tools its instructions call (pip). Our summary lists: Python 3; A Bash shell.
Does Bio Differential Splicing access the network?
SKILL.md contains no URLs. Its commands use pip, which can reach the network depending on how they are called. This is read from the text; nothing was executed.
Is Bio Differential Splicing safe to install?
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.
What licence does Bio Differential Splicing use?
No licence was found for Bio Differential Splicing or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.
How many tokens does Bio Differential Splicing use?
About 1.5k tokens (SKILL.md is roughly 6k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.
What are the alternatives to Bio Differential Splicing?
Skills that share tags, products or a category with Bio Differential Splicing: MCP Server Builder (anthropics/skills, 180k stars), PDF Processing (anthropics/skills, 180k stars), NotebookLM Research Assistant (PleasePrompto/notebooklm-skill, 7.8k stars) and Manim Video Production (browser-use/video-use, 28k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
Who maintains Bio Differential Splicing?
FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,052 GitHub stars. The repository holds 170 skills in this directory. The repository was last updated on July 21, 2026.
Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.