Agent skill

Bio Clinical Databases Polygenic Risk

by FreedomIntelligence in FreedomIntelligence/OpenClaw-Medical-Skills

Calculate polygenic risk scores using PRSice-2, LDpred2, or PRS-CS from GWAS summary statistics.

No licenceAuto-check passedData & Analytics

Install Bio Clinical Databases Polygenic Risk

skills CLI
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-clinical-databases-polygenic-risk -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-clinical-databases-polygenic-risk --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bio-clinical-databases-polygenic-risk .claude/skills/bio-clinical-databases-polygenic-risk && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
bio-clinical-databases-polygenic-risk
GitHub stars
3.1k
Token cost
~1.9k tokens
SKILL.md length
344 words
Files
4
Skills in repo
279
Repo updated
First seen
Licence
None found

At a glance

Calculate polygenic risk scores using PRSice-2, LDpred2, or PRS-CS from GWAS summary statistics.

  • Predicting disease risk from genome-wide genetic variants
  • SKILL.md covers Version Compatibility, PRSice-2 Workflow, GWAS Summary Statistics Format and LDpred2 (R), plus 6 more sections
  • Runs R and Shell scripts from its folder; calls python and pip; reaches pgscatalog.org
  • Tasks that involve Data analysis

What it does

Bio Clinical Databases Polygenic Risk is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Calculate polygenic risk scores using PRSice-2, LDpred2, or PRS-CS from GWAS summary statistics. Use when predicting disease risk from genome-wide genetic variants.

Its SKILL.md is about 1.9k tokens, which your agent loads only when the skill is triggered. The skill folder holds 4 other files (for example `examples/prsice2_workflow.sh` and `usage-guide.md`).

It sits in Data & Analytics, covering Data analysis and Bioinformatics. The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.

When your agent uses it

  • Predicting disease risk from genome-wide genetic variants
  • Tasks that involve Data analysis
  • Tasks that involve Bioinformatics

Example prompts

  • “/bio-clinical-databases-polygenic-risk”

Requirements

  • Python 3
  • A Bash shell

What it can do on your machine

Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships script files (R and Shell), which the agent can run.

    Shell commands in SKILL.md call:

    • python
    • pip

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    Hosts in commands or code, which the agent is likely to contact:

    • pgscatalog.org

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Bio Clinical Databases Polygenic Risk loads about 1.9k tokens when it runs. Until then it costs about 51 tokens; SKILL.md has 344 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~51
When it runs · the whole SKILL.md, loaded when a task matches
~1.9k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 344 words (~1,940 tokens).

“Reference examples tested with: LDpred2 1.14+, PRSice-2 2.3+, numpy 1.26+, scipy 1.12+”

— opening of SKILL.md by FreedomIntelligence
name
bio-clinical-databases-polygenic-risk
tool_type
mixed
primary_tool
PRSice-2

Read the full SKILL.md on GitHub

Files

SKILL.md and 3 other files in skills/bio-clinical-databases-polygenic-risk of FreedomIntelligence/OpenClaw-Medical-Skills.

  • SKILL.md
  • examples/ldpred2_analysis.R
  • examples/prsice2_workflow.sh
  • usage-guide.md

Open the folder on GitHubat commit b1f9b6e

Compare with similar skills

Bio Clinical Databases Polygenic Risk next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Bio Clinical Databases Polygenic Risk compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Bio Clinical Databases Polygenic Risk this skillFreedomIntelligence/OpenClaw-Medical-Skills3.1k—~1.9kAutomated safety check: PassNone
Exploratory Data Analysisspacering-net/codeg3.9k14 repos~3.6kAutomated safety check: PassMIT
Pyopenmsdavila7/claude-code-templates32k11 repos~1.4kAutomated safety check: PassMIT
Gwas Databasedavila7/claude-code-templates32k10 repos~5kAutomated safety check: PassMIT
Bioconductor BiomartbioMate-AI/biomate-bioconductor-kb804—~4.5kAutomated safety check: PassCustom licence
Bio Data Visualization Manhattan Qq LocuszoomGPTomics/bioSkills1.2k2 repos~4.3kAutomated safety check: PassMIT

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Questions about Bio Clinical Databases Polygenic Risk

What does Bio Clinical Databases Polygenic Risk do?

Calculate polygenic risk scores using PRSice-2, LDpred2, or PRS-CS from GWAS summary statistics. Bio Clinical Databases Polygenic Risk is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Calculate polygenic risk scores using PRSice-2, LDpred2, or PRS-CS from GWAS summary statistics.

When should I use Bio Clinical Databases Polygenic Risk?

Bio Clinical Databases Polygenic Risk fits situations like: predicting disease risk from genome-wide genetic variants; tasks that involve Data analysis; tasks that involve Bioinformatics.

How do I install Bio Clinical Databases Polygenic Risk in Claude Code?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-clinical-databases-polygenic-risk -a claude-code`. Or copy the skill folder (skills/bio-clinical-databases-polygenic-risk in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/bio-clinical-databases-polygenic-risk in your project. Claude Code loads it when a task matches its description.

How do I install Bio Clinical Databases Polygenic Risk in Codex?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-clinical-databases-polygenic-risk -a codex`. Or copy the skill folder (skills/bio-clinical-databases-polygenic-risk in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/bio-clinical-databases-polygenic-risk in your project. Codex loads it when a task matches its description.

Can I use Bio Clinical Databases Polygenic Risk in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-clinical-databases-polygenic-risk -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bio-clinical-databases-polygenic-risk, .gemini/skills/bio-clinical-databases-polygenic-risk, .github/skills/bio-clinical-databases-polygenic-risk and .opencode/skills/bio-clinical-databases-polygenic-risk in your project.

What does Bio Clinical Databases Polygenic Risk need to run?

Going by SKILL.md and its folder, Bio Clinical Databases Polygenic Risk needs R and a shell for the scripts in its folder and the command-line tools its instructions call (python and pip). Our summary lists: Python 3; A Bash shell.

Does Bio Clinical Databases Polygenic Risk access the network?

SKILL.md names 1 domain. In commands or code: pgscatalog.org; the agent is likely to contact it when it follows the instructions. This is read from the text; nothing was executed.

Is Bio Clinical Databases Polygenic Risk safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Bio Clinical Databases Polygenic Risk use?

No licence was found for Bio Clinical Databases Polygenic Risk or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Bio Clinical Databases Polygenic Risk use?

About 1.9k tokens (SKILL.md is roughly 7.8k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Bio Clinical Databases Polygenic Risk?

Skills that share tags, products or a category with Bio Clinical Databases Polygenic Risk: Exploratory Data Analysis (spacering-net/codeg, 3.9k stars), Pyopenms (davila7/claude-code-templates, 32k stars), Gwas Database (davila7/claude-code-templates, 32k stars) and Bioconductor Biomart (bioMate-AI/biomate-bioconductor-kb, 804 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Bio Clinical Databases Polygenic Risk?

FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,052 GitHub stars. The repository holds 279 skills in this directory. The repository was last updated on July 21, 2026.

Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.