PyDESeq2 Differential Expression
davila7/claude-code-templates
Runs differential gene expression analysis on bulk RNA-seq counts with PyDESeq2: design formulas, Wald tests, FDR correction and volcano or MA plots.
Agent skill
Bio Chipseq Differential Binding
by FreedomIntelligence in FreedomIntelligence/OpenClaw-Medical-Skills
Differential binding analysis using DiffBind. An agent skill from FreedomIntelligence/OpenClaw-Medical-Skills.
Install Bio Chipseq Differential Binding
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-differential-binding -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-chipseq-differential-binding --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bio-chipseq-differential-binding .claude/skills/bio-chipseq-differential-binding && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "bio-chipseq-differential-binding" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-chipseq-differential-binding into .claude/skills/bio-chipseq-differential-binding/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-chipseq-differential-binding", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-chipseq-differential-bindingType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-differential-binding -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-chipseq-differential-binding --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .agents/skills && cp -r skills-src/skills/bio-chipseq-differential-binding .agents/skills/bio-chipseq-differential-binding && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "bio-chipseq-differential-binding" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-chipseq-differential-binding into .agents/skills/bio-chipseq-differential-binding/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-chipseq-differential-binding", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-differential-binding -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-chipseq-differential-binding --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/skills/bio-chipseq-differential-binding .cursor/skills/bio-chipseq-differential-binding && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "bio-chipseq-differential-binding" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-chipseq-differential-binding into .cursor/skills/bio-chipseq-differential-binding/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-chipseq-differential-binding", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git --path skills/bio-chipseq-differential-binding--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-differential-binding -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-chipseq-differential-binding --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/skills/bio-chipseq-differential-binding .gemini/skills/bio-chipseq-differential-binding && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "bio-chipseq-differential-binding" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-chipseq-differential-binding into .gemini/skills/bio-chipseq-differential-binding/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-chipseq-differential-binding", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-chipseq-differential-bindingInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-differential-binding -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .github/skills && cp -r skills-src/skills/bio-chipseq-differential-binding .github/skills/bio-chipseq-differential-binding && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "bio-chipseq-differential-binding" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-chipseq-differential-binding into .github/skills/bio-chipseq-differential-binding/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-chipseq-differential-binding", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-differential-binding -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install FreedomIntelligence/OpenClaw-Medical-Skills bio-chipseq-differential-binding --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/skills/bio-chipseq-differential-binding .opencode/skills/bio-chipseq-differential-binding && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "bio-chipseq-differential-binding" agent skill from https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/tree/main/skills/bio-chipseq-differential-binding into .opencode/skills/bio-chipseq-differential-binding/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "bio-chipseq-differential-binding", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
Facts
- Skill name
bio-chipseq-differential-binding- GitHub stars
- 3.1k
- Token cost
- ~1.9k tokens
- SKILL.md length
- 465 words
- Files
- 3
- Skills in repo
- 279
- Repo updated
- First seen
- Licence
- None found
At a glance
Differential binding analysis using DiffBind. An agent skill from FreedomIntelligence/OpenClaw-Medical-Skills.
- Comparing ChIP-seq binding between conditions
- SKILL.md covers Version Compatibility, Create Sample Sheet, Load Data and Count Reads in Peaks, plus 15 more sections
- Runs R scripts from its folder
- Tasks that involve Bioinformatics
What it does
Bio Chipseq Differential Binding is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Differential binding analysis using DiffBind. Compare ChIP-seq peaks between conditions with statistical rigor. Requires replicate samples. Outputs differentially bound regions with fold changes and p-values. Use when comparing ChIP-seq binding between conditions.
Its SKILL.md is about 1.9k tokens, which your agent loads only when the skill is triggered. The skill folder holds 3 other files (for example `usage-guide.md`).
It sits in Research & Science, covering Bioinformatics and Statistics. The repository describes itself as: The largest open-source medical AI skills library for OpenClaw🦞.
When your agent uses it
- Comparing ChIP-seq binding between conditions
- Tasks that involve Bioinformatics
- Tasks that involve Statistics
Example prompts
- “/bio-chipseq-differential-binding”
What it can do on your machine
Read from SKILL.md and the folder at commit b1f9b6e. It shows what the files ask for, not the result of running them.
Tool permissions
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Runs code
Ships script files (R), which the agent can run.
From the folder's file list and the shell code blocks in SKILL.md.
Network
No URLs in SKILL.md.
From URLs in SKILL.md, links to its own repository left out.
Credentials
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
Context cost
Bio Chipseq Differential Binding loads about 1.9k tokens when it runs. Until then it costs about 74 tokens; SKILL.md has 465 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
Safety
Auto-check passed
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.
SKILL.md
Without a licence we can't republish the file, so here is its outline and opening line. It has 465 words (~1,883 tokens).
“Reference examples tested with: DESeq2 1.42+, edgeR 4.0+”
- name
- bio-chipseq-differential-binding
- tool_type
- r
- primary_tool
- DiffBind
Files
SKILL.md and 2 other files in skills/bio-chipseq-differential-binding of FreedomIntelligence/OpenClaw-Medical-Skills.
- SKILL.md
- examples/diffbind_analysis.R
- usage-guide.md
Open the folder on GitHubat commit b1f9b6e
Compare with similar skills
Bio Chipseq Differential Binding next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| Bio Chipseq Differential Binding this skillFreedomIntelligence/OpenClaw-Medical-Skills | 3.1k | — | ~1.9k | Automated safety check: Pass | None | |
| PyDESeq2 Differential Expressiondavila7/claude-code-templates | 32k | 11 repos | ~4k | Automated safety check: Pass | MIT | |
| Ukb Ppp Region FetchClawBio/ClawBio | 1.2k | — | ~4.6k | Automated safety check: Pass | MIT | |
| TiledbvcfK-Dense-AI/scientific-agent-skills | 48k | 1 repos | ~3.5k | Automated safety check: Pass | MIT | |
| Volcano Plot Scriptaipoch/medical-research-skills | 2k | — | ~2.5k | Automated safety check: Pass | MIT | |
| Tooluniverse Epigenomicswu-yc/LabClaw | 1.1k | 2 repos | ~14k | Automated safety check: Pass | None |
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aipoch/medical-research-skills
Generate R/Python code for volcano plots from DEG (Differentially Expressed Genes) analysis results.
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Production-ready genomics and epigenomics data processing for BixBench questions.
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Related
Categories
Questions about Bio Chipseq Differential Binding
What does Bio Chipseq Differential Binding do?
Differential binding analysis using DiffBind. An agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Bio Chipseq Differential Binding is an agent skill from FreedomIntelligence/OpenClaw-Medical-Skills. Differential binding analysis using DiffBind.
When should I use Bio Chipseq Differential Binding?
Bio Chipseq Differential Binding fits situations like: comparing ChIP-seq binding between conditions; tasks that involve Bioinformatics; tasks that involve Statistics.
How do I install Bio Chipseq Differential Binding in Claude Code?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-differential-binding -a claude-code`. Or copy the skill folder (skills/bio-chipseq-differential-binding in FreedomIntelligence/OpenClaw-Medical-Skills) into .claude/skills/bio-chipseq-differential-binding in your project. Claude Code loads it when a task matches its description.
How do I install Bio Chipseq Differential Binding in Codex?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-differential-binding -a codex`. Or copy the skill folder (skills/bio-chipseq-differential-binding in FreedomIntelligence/OpenClaw-Medical-Skills) into .agents/skills/bio-chipseq-differential-binding in your project. Codex loads it when a task matches its description.
Can I use Bio Chipseq Differential Binding in Cursor, Gemini CLI or GitHub Copilot?
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-chipseq-differential-binding -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bio-chipseq-differential-binding, .gemini/skills/bio-chipseq-differential-binding, .github/skills/bio-chipseq-differential-binding and .opencode/skills/bio-chipseq-differential-binding in your project.
What does Bio Chipseq Differential Binding need to run?
Going by SKILL.md and its folder, Bio Chipseq Differential Binding needs R for the scripts in its folder.
Does Bio Chipseq Differential Binding access the network?
SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.
Is Bio Chipseq Differential Binding safe to install?
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.
What licence does Bio Chipseq Differential Binding use?
No licence was found for Bio Chipseq Differential Binding or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.
How many tokens does Bio Chipseq Differential Binding use?
About 1.9k tokens (SKILL.md is roughly 7.5k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.
What are the alternatives to Bio Chipseq Differential Binding?
Skills that share tags, products or a category with Bio Chipseq Differential Binding: PyDESeq2 Differential Expression (davila7/claude-code-templates, 32k stars), Ukb Ppp Region Fetch (ClawBio/ClawBio, 1.2k stars), Tiledbvcf (K-Dense-AI/scientific-agent-skills, 48k stars) and Volcano Plot Script (aipoch/medical-research-skills, 2k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
Who maintains Bio Chipseq Differential Binding?
FreedomIntelligence (a GitHub organization) maintains it in FreedomIntelligence/OpenClaw-Medical-Skills, which has 3,052 GitHub stars. The repository holds 279 skills in this directory. The repository was last updated on July 21, 2026.
Source: FreedomIntelligence/OpenClaw-Medical-Skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.