Alphagenome Single Variant Analysis
google-deepmind/science-skills
Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API.
Aggregates QC reports from any bioinformatics tool outputs (FastQC, fastp, STAR, Picard, samtools, etc.) into a single MultiQC HTML report plus a ClawBio markdown summary with per-sample QC metrics.
$ npx skills add ClawBio/ClawBio --skill multiqc-reporter -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install ClawBio/ClawBio multiqc-reporter --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/ClawBio/ClawBio.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/multiqc-reporter .claude/skills/multiqc-reporter && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "multiqc-reporter" agent skill from https://github.com/ClawBio/ClawBio/tree/main/skills/multiqc-reporter into .claude/skills/multiqc-reporter/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "multiqc-reporter", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/ClawBio/ClawBio/tree/main/skills/multiqc-reporterType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add ClawBio/ClawBio --skill multiqc-reporter -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install ClawBio/ClawBio multiqc-reporter --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/ClawBio/ClawBio.git skills-src && mkdir -p .agents/skills && cp -r skills-src/skills/multiqc-reporter .agents/skills/multiqc-reporter && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "multiqc-reporter" agent skill from https://github.com/ClawBio/ClawBio/tree/main/skills/multiqc-reporter into .agents/skills/multiqc-reporter/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "multiqc-reporter", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add ClawBio/ClawBio --skill multiqc-reporter -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install ClawBio/ClawBio multiqc-reporter --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/ClawBio/ClawBio.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/skills/multiqc-reporter .cursor/skills/multiqc-reporter && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "multiqc-reporter" agent skill from https://github.com/ClawBio/ClawBio/tree/main/skills/multiqc-reporter into .cursor/skills/multiqc-reporter/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "multiqc-reporter", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/ClawBio/ClawBio.git --path skills/multiqc-reporter--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add ClawBio/ClawBio --skill multiqc-reporter -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install ClawBio/ClawBio multiqc-reporter --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/ClawBio/ClawBio.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/skills/multiqc-reporter .gemini/skills/multiqc-reporter && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "multiqc-reporter" agent skill from https://github.com/ClawBio/ClawBio/tree/main/skills/multiqc-reporter into .gemini/skills/multiqc-reporter/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "multiqc-reporter", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install ClawBio/ClawBio multiqc-reporterInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add ClawBio/ClawBio --skill multiqc-reporter -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/ClawBio/ClawBio.git skills-src && mkdir -p .github/skills && cp -r skills-src/skills/multiqc-reporter .github/skills/multiqc-reporter && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "multiqc-reporter" agent skill from https://github.com/ClawBio/ClawBio/tree/main/skills/multiqc-reporter into .github/skills/multiqc-reporter/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "multiqc-reporter", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add ClawBio/ClawBio --skill multiqc-reporter -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install ClawBio/ClawBio multiqc-reporter --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/ClawBio/ClawBio.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/skills/multiqc-reporter .opencode/skills/multiqc-reporter && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "multiqc-reporter" agent skill from https://github.com/ClawBio/ClawBio/tree/main/skills/multiqc-reporter into .opencode/skills/multiqc-reporter/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "multiqc-reporter", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
multiqc-reporterAggregates QC reports from any bioinformatics tool outputs (FastQC, fastp, STAR, Picard, samtools, etc.) into a single MultiQC HTML report plus a ClawBio markdown summary with per-sample QC metrics.
Multiqc Reporter is an agent skill from ClawBio/ClawBio. Aggregates QC reports from any bioinformatics tool outputs (FastQC, fastp, STAR, Picard, samtools, etc.) into a single MultiQC HTML report plus a ClawBio markdown summary with per-sample QC metrics.
Its SKILL.md is about 2.4k tokens, which your agent loads only when the skill is triggered. The skill folder holds 4 other files (for example `multiqc_reporter.py`, `tests/__init__.py` and `tests/test_multiqc_reporter.py`).
It sits in Research & Science, covering Bioinformatics. The repository describes itself as: 🦖 ClawBio - The first bioinformatics-native AI agent skill library. Local-first. Reproducible. Open. Free. The licence is MIT.
3 steps, taken from the first numbered list in SKILL.md.
Read from SKILL.md and the folder at commit dece754. It shows what the files ask for, not the result of running them.
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Ships script files (Python), which the agent can run.
Shell commands in SKILL.md call:
pythonpipFrom the folder's file list and the shell code blocks in SKILL.md.
Links to these hosts (documentation or services it may open):
doi.orgFrom URLs in SKILL.md, links to its own repository left out.
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
Multiqc Reporter loads about 2.4k tokens when it runs. Until then it costs about 54 tokens; SKILL.md has 816 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.
The full file from ClawBio/ClawBio at commit dece754, republished under its MIT licence (© ClawBio). 816 words, ~2,403 tokens.
.claude/skills/multiqc-reporter/SKILL.md (or your agent's skills folder). This skill also uses 3 other files; get the full folder from GitHub.You are MultiQC Reporter, a specialised ClawBio agent for aggregating bioinformatics QC reports across samples and tools into a single summary.
Fire this skill when the user says any of:
Do NOT fire when:
seq-wranglerrnaseq-descrna-orchestratorreport.md table of per-sample metricsreport.md extracted from MultiQC's JSON data, chainable with other skillsmultiqc_data/multiqc_data.json for per-sample metrics and renders them in report.md--demo runs without user data — generates synthetic FastQC output for 3 samples so MultiQC renders its full plot suiteOne skill, one task. This skill aggregates existing QC outputs via MultiQC.
It does NOT run FastQC, fastp, STAR, or any upstream tool — that is seq-wrangler's job.
| Format | Extension | Notes |
|---|---|---|
| FastQC output | fastqc_data.txt or *_fastqc.zip | Standard FastQC output directory |
| Any MultiQC-supported tool | varies | See multiqc.info for full list of 100+ tools |
When the user asks to aggregate QC reports:
multiqc is on PATH; exit with pip install multiqc hint if absent--input directories existmultiqc <dirs> --outdir <output> (MultiQC defaults)multiqc_data/multiqc_data.json for per-sample metricsreport.md with run metadata, per-sample QC table, and disclaimerreproducibility/commands.sh, environment.yml, and checksums.sha256# Standard — scan one or more directories
python skills/multiqc-reporter/multiqc_reporter.py \
--input <dir> [<dir2> ...] --output <report_dir>
# Demo mode (no user data required)
python skills/multiqc-reporter/multiqc_reporter.py --demo --output /tmp/multiqc_demomultiqc CLI with --outdir only (default MultiQC behaviour)multiqc_data/multiqc_data.json (report_general_stats_data): flatten {tool: {sample: metrics}} → {sample: {metric: value}}# MultiQC Report
**Date**: 2026-04-13 10:32 UTC
**Input directories**: /data/fastqc_out
## Per-Sample QC
| Sample | percent_duplicates | percent_gc | total_sequences |
|--------|--------------------|------------|-----------------|
| SAMPLE_01 | 5.5 | 49 | 1000000 |
| SAMPLE_02 | 15.0 | 50 | 920000 |
| SAMPLE_03 | 7.5 | 48 | 880000 |
## Outputs
- `multiqc_report.html` — interactive HTML report
- `multiqc_data/` — raw data files
## Reproducibility
- `reproducibility/commands.sh` — replay this ClawBio MultiQC run
- `reproducibility/environment.yml` — suggested conda environment
- `reproducibility/checksums.sha256` — key outputs
---
*ClawBio is a research and educational tool. It is not a medical device and does not provide clinical diagnoses. Consult a healthcare professional before making any medical decisions.*output_dir/
├── report.md # ClawBio markdown summary
├── multiqc_report.html # Standard MultiQC HTML
├── multiqc_data/
│ ├── multiqc_data.json # Structured stats (default MultiQC output)
│ └── ...
├── reproducibility/
│ ├── commands.sh # Exact replay command
│ ├── environment.yml # Suggested env (multiqc via pip)
│ └── checksums.sha256 # Output digestsExternal binary (not a Python package import):
multiqc >= 1.20; install with pip install multiqcPython (repo-local clawbio package for reproducibility helpers):
subprocess, json, shutil, argparse, tempfile, mathclawbio.common.reproducibility — commands.sh, environment.yml, checksums.sha256report_general_stats_data metric keys are already short (e.g. percent_duplicates, percent_gc) — no further processing needed. If the table looks empty, check that multiqc_data/multiqc_data.json exists and that report_general_stats_data is non-empty.--demo creates files in a tempfile.TemporaryDirectory that is deleted after run_multiqc returns. MultiQC has already written its outputs to --output by then, so nothing is lost. Don't move the with block boundary.report.md and an HTML report noting no modules were found.--export. Interactive plots remain in multiqc_report.html; for slide decks, run multiqc yourself with --export or export figures from the browser.report.md includes the ClawBio medical disclaimermultiqc_data/multiqc_data.jsonThe agent (LLM) dispatches and explains results. The skill (Python + MultiQC CLI) executes. The agent must NOT invent QC thresholds or interpret pass/warn/fail beyond what MultiQC reports.
Trigger conditions: the orchestrator routes here when:
Chaining partners:
seq-wrangler: produces FastQC/fastp/BAM stats directories → feed into multiqcrnaseq-de: STAR/HISAT2 alignment logs → feed into multiqc for alignment QCscrna-orchestrator: STARsolo per-sample QC dirs → feed into multiqcrepro-enforcer: folds the reproducibility/ trio into pipeline-wide bundlesmultiqc --version)report_general_stats_data still exists in multiqc_data.jsonskills/_deprecated/ if MultiQC adds a native ClawBio integration© ClawBio, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file
SKILL.md and 3 other files in skills/multiqc-reporter of ClawBio/ClawBio.
Open the folder on GitHubat commit dece754
We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in ClawBio/ClawBio, which our catalogue first saw on October 7, 2026.
Multiqc Reporter next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| Multiqc Reporter this skillClawBio/ClawBio | 1.2k | 1 repos | ~2.4k | Automated safety check: Pass | MIT | |
| Alphagenome Single Variant Analysisgoogle-deepmind/science-skills | 3.2k | 2 repos | ~3k | Automated safety check: Notes | Apache-2.0 | |
| 13C Metabolic Flux AnalysisK-Dense-AI/scientific-agent-skills | 48k | 1 repos | ~3.2k | Automated safety check: Pass | MIT | |
| Clinvar Databasegoogle-deepmind/science-skills | 3.2k | 2 repos | ~3.9k | Automated safety check: Notes | Apache-2.0 | |
| Metabolic Study Planneraiming-lab/AutoResearchClaw | 15k | — | ~1.9k | Automated safety check: Pass | MIT | |
| Dbsnp Databasegoogle-deepmind/science-skills | 3.2k | 2 repos | ~3.4k | Automated safety check: Notes | Apache-2.0 |
google-deepmind/science-skills
Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API.
K-Dense-AI/scientific-agent-skills
Estimates reaction fluxes inside cells from steady-state carbon-13 labeling data with a bundled mfapy-based solver, and reports which fluxes the data pin down.
google-deepmind/science-skills
A skill your agent uses when needing clinical significance, pathogenicity classifications (e.g., Pathogenic, Benign, VUS), clinical evidence rationales, or finding "hard positive" benchmark controls…
aiming-lab/AutoResearchClaw
Turns a broad metabolic modelling topic into a concrete, paper-shaped plan with organism, model, perturbations, metrics and figures before any FBA code is written.
google-deepmind/science-skills
A skill your agent uses when you want to look up, map, and search for short genetic variants (SNPs, indels) in NCBI's dbSNP database.
aiming-lab/AutoResearchClaw
Runs a metabolic flux analysis from model loading to phenotype prediction and figures by handing work to four sub-agents in sequence.
ClawBio/ClawBio
Fetch a region of cis-eQTL summary statistics from EBI eQTL Catalogue v7+ via tabix-on-FTP.
ClawBio/ClawBio
Query TCGA tumor biology through the ucscxenatoolspy API. An agent skill from ClawBio/ClawBio.
ClawBio/ClawBio
Fetch a region of GWAS summary statistics from the NHGRI-EBI GWAS Catalog harmonised collection via tabix-on-FTP.
ClawBio/ClawBio
Population genetics of pre-aligned DNA sequences or multi-sample VCFs using selected DnaSP 6 methods.
ClawBio/ClawBio
Compute pairwise r² between a lead variant and every variant in a window using the 1000 Genomes Phase 3 GRCh38 reference panel, ancestry-stratified.
ClawBio/ClawBio
Download genomes, genes, virus sequences, and taxonomy data from NCBI using the datasets and dataformat CLI tools.
Categories
Aggregates QC reports from any bioinformatics tool outputs (FastQC, fastp, STAR, Picard, samtools, etc.) into a single MultiQC HTML report plus a ClawBio markdown summary with per-sample QC metrics. Multiqc Reporter is an agent skill from ClawBio/ClawBio.) into a single MultiQC HTML report plus a ClawBio markdown summary with per-sample QC metrics.
Multiqc Reporter fits situations like: tasks that involve Bioinformatics.
Run `npx skills add ClawBio/ClawBio --skill multiqc-reporter -a claude-code`. Or copy the skill folder (skills/multiqc-reporter in ClawBio/ClawBio) into .claude/skills/multiqc-reporter in your project. Claude Code loads it when a task matches its description.
Run `npx skills add ClawBio/ClawBio --skill multiqc-reporter -a codex`. Or copy the skill folder (skills/multiqc-reporter in ClawBio/ClawBio) into .agents/skills/multiqc-reporter in your project. Codex loads it when a task matches its description.
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add ClawBio/ClawBio --skill multiqc-reporter -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/multiqc-reporter, .gemini/skills/multiqc-reporter, .github/skills/multiqc-reporter and .opencode/skills/multiqc-reporter in your project.
Going by SKILL.md and its folder, Multiqc Reporter needs Python for the scripts in its folder and the command-line tools its instructions call (python and pip). Our summary lists: Python 3.
SKILL.md names 1 domain. As links in the text: doi.org. This is read from the text; nothing was executed.
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.
Multiqc Reporter is published under the MIT licence (declared in SKILL.md). It allows redistribution, so the full SKILL.md is shown on this page.
About 2.4k tokens (SKILL.md is roughly 9.6k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.
Skills that share tags, products or a category with Multiqc Reporter: Alphagenome Single Variant Analysis (google-deepmind/science-skills, 3.2k stars), 13C Metabolic Flux Analysis (K-Dense-AI/scientific-agent-skills, 48k stars), Clinvar Database (google-deepmind/science-skills, 3.2k stars) and Metabolic Study Planner (aiming-lab/AutoResearchClaw, 15k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
ClawBio (a GitHub organization) maintains it in ClawBio/ClawBio, which has 1,155 GitHub stars. The repository holds 104 skills in this directory. The repository was last updated on October 9, 2026.
Source: ClawBio/ClawBio on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.