Agent skill

Fda Qsr Audit Prep

by alirezarezvani in alirezarezvani/claude-skills

/cs:fda-qsr-audit-prep <scope — FDA 21 CFR 820 (QSR / QMSR) audit 6-question forcing interrogation.

MITAuto-check passedLegal & Compliance

Install Fda Qsr Audit Prep

skills CLI
$ npx skills add alirezarezvani/claude-skills --skill fda-qsr-audit-prep -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install alirezarezvani/claude-skills fda-qsr-audit-prep --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/alirezarezvani/claude-skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/compliance-os/skills/fda-qsr-audit-prep .claude/skills/fda-qsr-audit-prep && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
fda-qsr-audit-prep
GitHub stars
28k
Token cost
~1.6k tokens
SKILL.md length
456 words
Files
1
Skills in repo
342
Repo updated
First seen
Licence
MIT

At a glance

/cs:fda-qsr-audit-prep <scope — FDA 21 CFR 820 (QSR / QMSR) audit 6-question forcing interrogation.

  • Works in 6 steps: Show me the complaint files from the… → When was process validation (IQ/OQ/PQ)… → Show me the DHRs for products… → …
  • Legal & Compliance work in your project
  • SKILL.md covers When to Run, The Six QSR Questions, Workflow and Output Format, plus 2 more sections
  • Calls python

What it does

Fda Qsr Audit Prep is an agent skill from alirezarezvani/claude-skills. /cs:fda-qsr-audit-prep <scope — FDA 21 CFR 820 (QSR / QMSR) audit 6-question forcing interrogation. Post-Feb 2026 substantially harmonized with ISO 13485. Use before annual internal QSR audit, pre-FDA-inspection readiness, or Form 483 response.

Its SKILL.md is about 1.6k tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.

It sits in Legal & Compliance. The repository describes itself as: 380 Claude Code skills & agent skills & plugins (30+ Agents, 70+ custom commands, 380+ skills, customizable references, scripts)for Claude Code, Codex, Gemini CLI, Cursor, and 8… The licence is MIT.

When your agent uses it

  • Legal & Compliance work in your project

Example prompts

  • “/fda-qsr-audit-prep”

Requirements

  • Python 3

Workflow steps

6 steps, taken from the step headings in SKILL.md.

  1. Show me the complaint files from the last quarter — and the corresponding MDR reports.
  2. When was process validation (IQ/OQ/PQ) last revalidated per 21 CFR 820.75?
  3. Show me the DHRs for products commercially distributed in last 2 years.
  4. Show me CAPAs from the last 6 months with effectiveness verification.
  5. Show me labeling (21 CFR 801) review for the most recent product launch.
  6. If a Form 483 was issued in the last 3 years, show me the closure status.

What it can do on your machine

Read from SKILL.md and the folder at commit 19392f7. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Shell commands in SKILL.md call:

    • python

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Fda Qsr Audit Prep loads about 1.6k tokens when it runs. Until then it costs about 66 tokens; SKILL.md has 456 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~66
When it runs · the whole SKILL.md, loaded when a task matches
~1.6k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from alirezarezvani/claude-skills at commit 19392f7, republished under its MIT licence (© alirezarezvani). 456 words, ~1,599 tokens.

Download SKILL.mdSave it as .claude/skills/fda-qsr-audit-prep/SKILL.md (or your agent's skills folder).
name
fda-qsr-audit-prep
description
/cs:fda-qsr-audit-prep <scope> — FDA 21 CFR 820 (QSR / QMSR) audit 6-question forcing interrogation. Post-Feb 2026 substantially harmonized with ISO 13485. Use before annual internal QSR audit, pre-FDA-inspection readiness, or Form 483 response.

/cs:fda-qsr-audit-prep — FDA QSR Forcing Questions

Command: /cs:fda-qsr-audit-prep <scope>

The FDA QSR auditor pressure-tests any US medical-device QSR work. Six questions before any internal audit, FDA inspection, Form 483 response, or recall decision.

When to Run

  • Before annual internal QSR audit
  • Before pre-FDA-inspection readiness review (any device commercially distributed in US)
  • After receiving Form 483 observations
  • After Warning Letter receipt
  • After MDR-reportable event
  • Before recall decision (voluntary vs FDA-initiated)
  • Before submitting 510(k) / PMA (where QSR posture affects approval timeline)

The Six QSR Questions

1. Show me the complaint files from the last quarter — and the corresponding MDR reports.

21 CFR 820.198 + 21 CFR 803 — most-cited FDA inspection area.

  • Complaint log complete: who / what / when / device / batch
  • Investigation closure within reasonable timeline
  • MDR-reporting decision tree applied: death OR serious injury OR malfunction-that-could-cause = MDR
  • 30-day timeline for most MDR reports; 5 days for certain serious events
  • Complaint trending input to management review
2. When was process validation (IQ/OQ/PQ) last revalidated per 21 CFR 820.75?

Cross-walks ISO 13485 Clause 7.5.6 (substantially harmonized post-Feb 2026).

  • Initial validation at process introduction
  • Revalidation triggers: process / equipment / material change OR periodic schedule
  • Statistical techniques per 21 CFR 820.250 where applicable
  • Cross-check with cs-cqm-iso13485 for ISO 13485 alignment
3. Show me the DHRs for products commercially distributed in last 2 years.

21 CFR 820.180 — 2-year retention from commercial distribution; check sampling for completeness.

  • Device History Record (DHR) for each unit/lot/batch
  • Must include: dates of manufacture, quantity manufactured, quantity released, acceptance records, primary identification label, device identification, control number
  • Sample stratified by product class
  • Verify DHR closeness to DHF (design history file)
Show full SKILL.md (194 more words)Show less
4. Show me CAPAs from the last 6 months with effectiveness verification.

21 CFR 820.100 = ISO 13485 8.5.2 substantially harmonized.

  • Root cause analysis depth (5 Why minimum)
  • Effectiveness verification = measurable evidence, not "we updated the procedure"
  • Containment / correction / corrective action distinction documented
  • Closure approval by appropriate authority
  • Aging CAPAs > 90 days flagged
5. Show me labeling (21 CFR 801) review for the most recent product launch.

FDA-specific overlay not in ISO 13485.

  • Labeling per 21 CFR 801 requirements
  • For specific device types: also 21 CFR 800 series sectoral overlays
  • UDI (Unique Device Identification) per 21 CFR 830
  • Promotional materials reviewed for accuracy + non-misleading
6. If a Form 483 was issued in the last 3 years, show me the closure status.

Form 483 = FDA observation; not equivalent to ISO nonconformity.

  • Response within 15 working days
  • Each observation has documented corrective + preventive action with timeline
  • Effectiveness verification evidence
  • For Warning Letters: separate response track + potentially FDA meeting

Workflow

bash
# 1. QSR compliance posture
python ra-qm-team/skills/fda-consultant-specialist/scripts/qsr_compliance_checker.py compliance_state.json

# 2. FDA submission tracking (510(k) / PMA / IDE)
python ra-qm-team/skills/fda-consultant-specialist/scripts/fda_submission_tracker.py submissions.json

# 3. HIPAA overlap (if connected device handles PHI)
python ra-qm-team/skills/fda-consultant-specialist/scripts/hipaa_risk_assessment.py phi_inventory.json

# 4. Mock FDA inspection
python ../../skills/compliance-os/scripts/audit_simulator.py fda_qsr_scope.json

Output Format

markdown
# FDA QSR Audit Prep: <scope>
**Date:** YYYY-MM-DD

## The Decision Being Made
[programme-plan | inspection-readiness | 483-response | MDR-decision | recall]

## Complaint + MDR Posture
- Complaints last quarter: N
- MDR-reportable events: M
- MDR reports filed within timeline: % (target 100%)
- Complaint trending review at management level: yes/no

## Process Validation Status (21 CFR 820.75)
- Validations on schedule: %
- Stale validations: <list>
- Statistical techniques applied: yes/no per process

## DHR Completeness (21 CFR 820.180)
- DHRs sampled: N
- Completeness rate: %
- 2-year retention compliant: yes/no
- Stratified by product class: yes/no

## CAPA Health (21 CFR 820.100)
- CAPAs sampled: N
- Root cause analysis depth: adequate/inadequate
- Effectiveness verification: complete/incomplete
- Aging CAPAs > 90 days: N

## Labeling (21 CFR 801)
- Recent products reviewed: <list>
- Labeling accurate + non-misleading: yes/no
- UDI compliance per 21 CFR 830: yes/no

## Form 483 / Warning Letter History
- Form 483s last 3 years: N (each: closed/in-progress)
- Warning Letters last 5 years: N (each: closed/in-progress)
- Pattern across observations: <thematic>

## ISO 13485 Cross-Walk (post-Feb 2026 harmonization)
- ISO 13485 audit findings: <link to cs-cqm-iso13485 output>
- FDA-specific overlays remaining: labeling + complaint handling + MDR reporting + recall procedures
- Cross-framework reuse: % of evidence shared

## Verdict
🟢 INSPECTION-READY | 🟡 GAPS-IDENTIFIED | 🔴 NOT-READY

## Top 3 Actions
[3 concrete next steps with owner + FDA-cited timeline (15 days / 30 days / etc.)]

## Outside Counsel Required
[For Warning Letter response, recall decisions, or 510(k) / PMA strategy disputes]

Routing

  • /cs:compliance-readiness — for multi-framework view
  • /cs:iso13485-audit-prep — for ISO 13485 cross-walk pair (substantially harmonized)
  • /cs:gdpr-audit-prep — if connected device handles personal data
  • /cs:gc-review — for Warning Letter response coordination

Version: 1.0.0

© alirezarezvani, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

Just SKILL.md in compliance-os/skills/fda-qsr-audit-prep of alirezarezvani/claude-skills.

Open the folder on GitHubat commit 19392f7

Compare with similar skills

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Contract Reviewevolsb/claude-legal-skill4641 repos~3.6kAutomated safety check: PassMIT
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Paper To Cn Patentsnipp-zha/Paper-to-patent-Skill1061 repos~959Automated safety check: PassNone

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Questions about Fda Qsr Audit Prep

What does Fda Qsr Audit Prep do?

/cs:fda-qsr-audit-prep <scope — FDA 21 CFR 820 (QSR / QMSR) audit 6-question forcing interrogation. Fda Qsr Audit Prep is an agent skill from alirezarezvani/claude-skills. /cs:fda-qsr-audit-prep <scope — FDA 21 CFR 820 (QSR / QMSR) audit 6-question forcing interrogation.

When should I use Fda Qsr Audit Prep?

Fda Qsr Audit Prep fits situations like: legal & Compliance work in your project.

How do I install Fda Qsr Audit Prep in Claude Code?

Run `npx skills add alirezarezvani/claude-skills --skill fda-qsr-audit-prep -a claude-code`. Or copy the skill folder (compliance-os/skills/fda-qsr-audit-prep in alirezarezvani/claude-skills) into .claude/skills/fda-qsr-audit-prep in your project. Claude Code loads it when a task matches its description.

How do I install Fda Qsr Audit Prep in Codex?

Run `npx skills add alirezarezvani/claude-skills --skill fda-qsr-audit-prep -a codex`. Or copy the skill folder (compliance-os/skills/fda-qsr-audit-prep in alirezarezvani/claude-skills) into .agents/skills/fda-qsr-audit-prep in your project. Codex loads it when a task matches its description.

Can I use Fda Qsr Audit Prep in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add alirezarezvani/claude-skills --skill fda-qsr-audit-prep -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/fda-qsr-audit-prep, .gemini/skills/fda-qsr-audit-prep, .github/skills/fda-qsr-audit-prep and .opencode/skills/fda-qsr-audit-prep in your project.

What does Fda Qsr Audit Prep need to run?

Going by SKILL.md and its folder, Fda Qsr Audit Prep needs the command-line tools its instructions call (python). Our summary lists: Python 3.

Does Fda Qsr Audit Prep access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Fda Qsr Audit Prep safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Fda Qsr Audit Prep use?

Fda Qsr Audit Prep is published under the MIT licence (the repository's licence). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Fda Qsr Audit Prep use?

About 1.6k tokens (SKILL.md is roughly 6.4k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Fda Qsr Audit Prep?

Skills that share tags, products or a category with Fda Qsr Audit Prep: Paper to Chinese Patent Drafter (Yuan1z0825/nature-skills, 47k stars), C15t (c15t/c15t, 1.9k stars), Contract Review (evolsb/claude-legal-skill, 464 stars) and Legal Clinic Client Intake (anthropics/claude-for-legal, 9.6k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Fda Qsr Audit Prep?

alirezarezvani (a GitHub user) maintains it in alirezarezvani/claude-skills, which has 27,891 GitHub stars. The repository holds 342 skills in this directory. The repository was last updated on August 30, 2026.

Source: alirezarezvani/claude-skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.