Official agent skill

Codonfm Setup

by NVIDIA in NVIDIA/skills

Set up the public CodonFM v1 repository and download public Encodon checkpoints.

OfficialApache-2.0Auto-check passedDevOps & Cloud

Install Codonfm Setup

skills CLI
$ npx skills add NVIDIA/skills --skill codonfm-setup -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install NVIDIA/skills codonfm-setup --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/NVIDIA/skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/bionemo-codonfm-setup .claude/skills/codonfm-setup && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
codonfm-setup
GitHub stars
3.6k
Used in
1 other repo
Token cost
~3.3k tokens
SKILL.md length
1,434 words
Files
9
Skills in repo
390
Repo updated
First seen
Licence
Apache-2.0

At a glance

Set up the public CodonFM v1 repository and download public Encodon checkpoints.

  • Works in 5 steps: Determine whether the user wants… → For setup instructions or runtime work,… → Check the public-v1 boundaries. For an… → …
  • Requests to build
  • SKILL.md covers Instructions, Reporting setup instructions, Runtime preflight and Build and launch, plus 5 more sections
  • Calls python, hf and docker

What it does

Codonfm Setup is an agent skill from NVIDIA/skills, published by the product's own GitHub organization. Set up the public CodonFM v1 repository and download public Encodon checkpoints. Use for requests to build or launch the CodonFM development container, configure local data/checkpoint mounts, verify GPU access, or download public Encodon 80M, 600M, 1B, or Cdwt-1B weights. Do not use for Decodon, Encodon 5B/10B, missense-aggregation, or codon-optimization setup because those implementations are not in the public repository.

Its SKILL.md is about 3.3k tokens, which your agent loads only when the skill is triggered. The skill folder holds 11 other files (for example `BENCHMARK.md`, `agents/openai.yaml` and `evals/config.yml`).

It sits in DevOps & Cloud. It works with Docker. The repository describes itself as: Agent Skills for NVIDIA products — install into Claude Code, Codex, and other coding agents to run Physical AI, robotics, simulation, CUDA, and RAG workflows end to end. The licence is Apache-2.0.

When your agent uses it

  • Requests to build
  • Launch the CodonFM development container
  • Configure local data/checkpoint mounts
  • Verify GPU access

Example prompts

  • “/codonfm-setup”

Requirements

  • Python 3
  • Docker

Workflow steps

5 steps, taken from the first numbered list in SKILL.md.

  1. Determine whether the user wants instructions, a downloaded checkpoint, a
  2. For setup instructions or runtime work, inspect the supplied files and
  3. Check the public-v1 boundaries. For an unsupported
  4. Reuse available environments and checkpoints, and choose explicit paths
  5. Follow only the requested paths below. Environment setup alone does not

What it can do on your machine

Read from SKILL.md and the folder at commit 14a98ae. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Shell commands in SKILL.md call:

    • python
    • hf
    • docker
    • bash

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    Links to these hosts (documentation or services it may open):

    • docs.nvidia.com
    • huggingface.co

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Codonfm Setup loads about 3.3k tokens when it runs. Until then it costs about 110 tokens; SKILL.md has 1,434 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~110
When it runs · the whole SKILL.md, loaded when a task matches
~3.3k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from NVIDIA/skills at commit 14a98ae, republished under its Apache-2.0 licence (© NVIDIA). 1,434 words, ~3,277 tokens.

Download SKILL.mdSave it as .claude/skills/codonfm-setup/SKILL.md (or your agent's skills folder). This skill also uses 8 other files; get the full folder from GitHub.
name
codonfm-setup
description
Set up the public CodonFM v1 repository and download public Encodon checkpoints. Use for requests to build or launch the CodonFM development container, configure local data/checkpoint mounts, verify GPU access, or download public Encodon 80M, 600M, 1B, or Cdwt-1B weights. Do not use for Decodon, Encodon 5B/10B, missense-aggregation, or codon-optimization setup because those implementations are not in the public repository.
metadata.author
NVIDIA BioNeMo <bionemofeedback@nvidia.com>

CodonFM public setup

Operate from the public CodonFM repository root. Support only the checked-in public v1 code and public Encodon checkpoints.

Instructions

  1. Determine whether the user wants instructions, a downloaded checkpoint, a working model environment, or a combination of these.
  2. For setup instructions or runtime work, inspect the supplied files and configuration directly: the runner, model configuration, Dockerfile, launcher, and requirements. Runtime setup requires a checkout; a supplied source archive is sufficient for preparing instructions.
  3. Check the public-v1 boundaries. For an unsupported request, inspect MODEL_ARCHITECTURES in src/config.py, the model modules, and any requested script before explaining the boundary and ending that path. Runner argument choices alone do not establish implementation support.
  4. Reuse available environments and checkpoints, and choose explicit paths from the user's project.
  5. Follow only the requested paths below. Environment setup alone does not require a checkpoint download; download weights only when the request needs them and a suitable local checkpoint is unavailable.
Requested scopeAction and completion condition
Instructions onlyInspect the supplied source/configuration, provide the commands described under Reporting setup instructions, then stop. No installation or GPU verification is required.
Checkpoint onlyFollow Download a checkpoint, check the downloaded files, report their paths, then stop. No Docker, GPU, or model runtime is required.
Working model environmentFollow Runtime preflight, choose the container or direct-host path, then Verify the runtime. Report the checks performed and any remaining limitations.

For supplied source archives, inspect selected files with the available Python 3 standard library (zipfile.ZipFile.namelist() and read()) without extracting the whole archive. If extraction is needed, use a fresh directory from mktemp -d or tempfile.mkdtemp(). Preserve existing checkouts and temporary directories; do not delete or overwrite them to prepare a source inspection.

The runner's optional --dryrun requires the ML dependencies to be installed already. It constructs runtime configuration, then stops before execution. It does not install packages, validate CSV data, or load weights. Preparing setup instructions does not require running it.

Reporting setup instructions

For instruction requests, put complete commands for the requested setup path early in a compact, self-contained answer, even when also writing a guide file.

  • For downloads, use supplied checkpoint metadata for the exact repository, revision, weight filename, and config.json. Show the destination directory and keep the weights and configuration together.
  • For containers, state Docker/GPU prerequisites, explain existing-container replacement before the launcher command, and show explicit host data and checkpoint paths and the checkpoint mount at /data/checkpoints.
  • For direct-host setup, include python3.11 -m venv, python -m pip install -r requirements.txt, a writable MPLCONFIGDIR, torch.cuda.is_available() verification, and explicit host checkpoint paths.
  • State which checks actually ran and what remains unverified before model execution. Written instructions alone do not establish a working environment.

For a compatibility-only question, give the source-backed availability answer without adding an unrelated installation procedure.

Runtime preflight

For a working environment, check hardware before installing the runtime: use nvidia-smi if available, or check CUDA through an existing PyTorch installation. Actual model execution requires the ML dependencies and a compatible NVIDIA GPU. Compare the driver with the CUDA version required by the selected runtime using NVIDIA's compatibility guidance. For the Dockerfile's nvcr.io/nvidia/pytorch:24.10-py3 base, also check the 24.10 driver requirements. If a prerequisite is missing, follow Failure handling below.

Container preflight
  1. Confirm Dockerfile, run_dev.sh, and src/runner.py exist.
  2. Confirm docker info succeeds. Docker must have NVIDIA Container Toolkit configured for --gpus all; host GPU visibility alone does not establish container GPU access. Verify access in the launched container below.
  3. Run bash -n run_dev.sh before launching it.
  4. Resolve existing absolute host paths for data and checkpoints. Always pass both path flags to the launcher rather than relying on /data/codonfm defaults. Create missing project directories only as needed for the request.
  5. Check for an existing container before launch:
bash
docker ps -a --filter name='^/codon-fm-dev-container$'

If an exact-name container is running, run_dev.sh stops and removes it; tell the user before replacement. If it is stopped, the script cannot reuse the name, so obtain confirmation before removing it with docker rm codon-fm-dev-container. If removal is declined, preserve the container, skip this launch, and report the name conflict.

The public script uses host networking/IPC and mounts the user's SSH directory read-only; disclose this before execution. It has no opt-out flags for these settings. If they conflict with the user's constraints, use the direct-host path when feasible; otherwise report that container launch remains blocked.

Build and launch

Set CODONFM_REPO_DIR, CODONFM_DATA_DIR, and CODONFM_CHECKPOINT_DIR to existing absolute paths chosen for the project.

bash
cd "${CODONFM_REPO_DIR:?Set the repository path}"
bash run_dev.sh \
    --data-dir "${CODONFM_DATA_DIR:?Set the host data path}" \
    --checkpoints-dir "${CODONFM_CHECKPOINT_DIR:?Set the host checkpoint path}"

The host checkpoint directory is mounted at /data/checkpoints inside the container. The image is codon-fm-dev; the container is codon-fm-dev-container.

Use only the checked-in public code and the dependency versions declared in its Dockerfile and requirements.txt. Continue to Verify the runtime after launch; checkpoint downloads are a separate requested action.

Run directly without Docker

Use this path when the user prefers host execution or Docker is unavailable. It requires a compatible NVIDIA driver, Python 3.11 for the commands below, and a writable checkout. Confirm python3.11 --version succeeds before installation. Reuse a compatible project environment; otherwise create a dedicated virtual environment. Set CODONFM_CACHE_DIR to a writable cache directory before running these commands:

bash
cd "${CODONFM_REPO_DIR:?Set the repository path}"
python3.11 -m venv .venv
. .venv/bin/activate
python -m pip install --upgrade pip
python -m pip install -r requirements.txt
mkdir -p "${CODONFM_CACHE_DIR:?Set a writable cache path}/matplotlib"
export MPLCONFIGDIR="$CODONFM_CACHE_DIR/matplotlib"
python -c "import sys, torch; available = torch.cuda.is_available(); \
print(available, torch.cuda.get_device_name(0) if available else 'CUDA unavailable'); \
sys.exit(0 if available else 1)"

The last command is the direct-host GPU verification; interpret it as described under Verify the runtime. The requirements file configures the CUDA 12.4 PyTorch index for xFormers. Use explicit host paths in subsequent runner commands; no /data/checkpoints mount is created on this path.

Show full SKILL.md (542 more words)Show less

Download a checkpoint

Run only for a requested checkpoint. Reuse a suitable local copy first. Check hf --help and hf download --help in the environment that will perform the download. If the CLI is missing, use a separate download virtual environment and python -m pip install huggingface_hub; preserve the model environment's dependency versions. The CLI documentation describes installation and supported options. Public ungated downloads do not require hf auth login.

Set CODONFM_CHECKPOINT_DIR to an absolute writable directory in the environment running hf: the chosen host checkpoint root on the host, or /data/checkpoints inside the launched container. Host shell variables are not automatically set inside the container. Use supplied metadata for exact filenames and revisions; keep the weights and config.json together.

For the public 1B checkpoint:

bash
hf download nvidia/NV-CodonFM-Encodon-1B-v1 \
    NV-CodonFM-Encodon-1B-v1.safetensors config.json \
    --local-dir "${CODONFM_CHECKPOINT_DIR:?Set the checkpoint root}/encodon-1b"
Small checkpoint example

For a small demonstration, prefer the original public Encodon 80M weights:

bash
hf download nvidia/NV-CodonFM-Encodon-80M-v1 \
    NV-CodonFM-Encodon-80M-v1.safetensors config.json \
    --revision 399ca9fe17b57941a7bebc6788033919b417413c \
    --local-dir "${CODONFM_CHECKPOINT_DIR:?Set the checkpoint root}/encodon-80m"

The checkpoint is publicly accessible without a gated-model approval, and the weight file is 307,351,588 bytes. It need not be mirrored to GitHub LFS. The -TE- model IDs use TransformerEngine in bionemo-recipes; use the original model IDs with this public CodonFM codebase. Download only the weights and config.json, and reuse an existing local checkpoint.

Other supported public model IDs are:

  • nvidia/NV-CodonFM-Encodon-80M-v1
  • nvidia/NV-CodonFM-Encodon-600M-v1
  • nvidia/NV-CodonFM-Encodon-Cdwt-1B-v1

Use --model_name encodon_80m, encodon_600m, or encodon_1b according to architecture size. Cdwt-1B uses encodon_1b because Cdwt is a checkpoint training property, not a separate architecture.

For .safetensors, keep config.json in the same directory as the model file. Never invent a Decodon or undocumented checkpoint path.

After a successful download, confirm the expected files exist, config.json parses, and any supplied byte size or checksum matches. Report the absolute file paths and revision. A checkpoint-only request ends here; it does not continue to GPU verification. For a combined request, continue only the other requested path.

Verify the runtime

This section applies only to working-environment requests. For direct-host execution, use the GPU check at the end of Run directly without Docker in the model's activated environment. For a running container, use a host terminal:

bash
docker exec codon-fm-dev-container python -c \
    "import sys, torch; available = torch.cuda.is_available(); \
print(available, torch.cuda.get_device_name(0) if available else 'CUDA unavailable'); \
sys.exit(0 if available else 1)"

Expect True, a GPU name, and exit status zero. False or an exception means runtime verification failed; report the missing prerequisite or error. A CUDA check establishes GPU access, not successful checkpoint loading or model execution. Finish the environment request by reporting the verified runtime, available checkpoint paths, and any checks that remain unperformed.

Failure handling

  • If a command fails, diagnose the reported cause. Retry an unchanged command at most once for a transient failure, such as a download timeout. For a persistent failure, stop that path and report the error and needed fix.
  • For failed downloads, preserve the cache and partial files, retry the same supported command when appropriate, and report which files remain missing or unverified. Do not invent retry flags or claim an incomplete download succeeded.
  • If runtime prerequisites or container constraints cannot be met, complete independent work within the request: inspect supplied source/configuration, prepare setup commands, or download a requested checkpoint when possible. Report completed work and the unmet prerequisites; do not claim the runtime is working.

Public-v1 boundaries

  • Supported: Encodon 80M, 600M, 1B, and Cdwt-1B.
  • Not supported: Decodon, Encodon 5B/10B, sequence generation, specialized missense aggregation/fine-tuning, and scripts/codon_optimize.py.
  • CodonFM consumes coding sequences. It is not a variant caller, aligner, GTF annotator, or general VCF analysis tool.

© NVIDIA, Apache-2.0. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

SKILL.md and 8 other files in skills/bionemo-codonfm-setup of NVIDIA/skills.

  • SKILL.md
  • BENCHMARK.md
  • agents/openai.yaml
  • evals/config.yml
  • evals/evals.json
  • evals/files/codonfm_source.zip
  • evals/files/encodon_checkpoint.json
  • skill-card.md
  • skill.oms.sig

Open the folder on GitHubat commit 14a98ae

Used in 1 other repository

We found 2 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in NVIDIA/skills, which our catalogue first saw on October 10, 2026.

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Works with

Categories

Questions about Codonfm Setup

What does Codonfm Setup do?

Set up the public CodonFM v1 repository and download public Encodon checkpoints. Codonfm Setup is an agent skill from NVIDIA/skills, published by the product's own GitHub organization. Set up the public CodonFM v1 repository and download public Encodon checkpoints.

When should I use Codonfm Setup?

Codonfm Setup fits situations like: requests to build; launch the CodonFM development container; configure local data/checkpoint mounts; verify GPU access.

How do I install Codonfm Setup in Claude Code?

Run `npx skills add NVIDIA/skills --skill codonfm-setup -a claude-code`. Or copy the skill folder (skills/bionemo-codonfm-setup in NVIDIA/skills) into .claude/skills/codonfm-setup in your project. Claude Code loads it when a task matches its description.

How do I install Codonfm Setup in Codex?

Run `npx skills add NVIDIA/skills --skill codonfm-setup -a codex`. Or copy the skill folder (skills/bionemo-codonfm-setup in NVIDIA/skills) into .agents/skills/codonfm-setup in your project. Codex loads it when a task matches its description.

Can I use Codonfm Setup in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add NVIDIA/skills --skill codonfm-setup -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/codonfm-setup, .gemini/skills/codonfm-setup, .github/skills/codonfm-setup and .opencode/skills/codonfm-setup in your project.

What does Codonfm Setup need to run?

Going by SKILL.md and its folder, Codonfm Setup needs the command-line tools its instructions call (python, hf, docker and bash). Our summary lists: Python 3; Docker.

Does Codonfm Setup access the network?

SKILL.md names 2 domains. As links in the text: docs.nvidia.com and huggingface.co. This is read from the text; nothing was executed.

Is Codonfm Setup safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Codonfm Setup use?

Codonfm Setup is published under the Apache-2.0 licence (the repository's licence). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Codonfm Setup use?

About 3.3k tokens (SKILL.md is roughly 13k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Codonfm Setup?

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Who maintains Codonfm Setup?

NVIDIA (a GitHub organization, an official publisher) maintains it in NVIDIA/skills, which has 3,555 GitHub stars. The repository holds 390 skills in this directory. The repository was last updated on October 9, 2026.

Source: NVIDIA/skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.