Agent skill

Genome Compare

Compare your genome to George Church (PGP-1) and estimate ancestry composition

Install Genome Compare

skills CLI

$ npx skills add aAAaqwq/AGI-Super-Team --skill genome-compare -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI

$ gh skill install aAAaqwq/AGI-Super-Team genome-compare --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy

$ git clone --depth 1 https://github.com/aAAaqwq/AGI-Super-Team.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/genome-compare .claude/skills/genome-compare && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Paste into Claude Code

Install the "genome-compare" agent skill from https://github.com/aAAaqwq/AGI-Super-Team/tree/main/skills/genome-compare into .claude/skills/genome-compare/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-compare", then confirm the skill loads.

Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

$skill-installer

$skill-installer install https://github.com/aAAaqwq/AGI-Super-Team/tree/main/skills/genome-compare

Type this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.

skills CLI

$ npx skills add aAAaqwq/AGI-Super-Team --skill genome-compare -a codex

Project install goes to .agents/skills/; add -g for ~/.codex/skills/.

GitHub CLI

$ gh skill install aAAaqwq/AGI-Super-Team genome-compare --agent codex

Project scope by default (.agents/skills/); add --scope user for a personal install.

Manual copy

$ git clone --depth 1 https://github.com/aAAaqwq/AGI-Super-Team.git skills-src && mkdir -p .agents/skills && cp -r skills-src/skills/genome-compare .agents/skills/genome-compare && rm -rf skills-src

Use ~/.agents/skills/ instead of .agents/skills for a personal install.

Codex skills documentation · loads skills from .agents/skills/

Paste into Codex

Install the "genome-compare" agent skill from https://github.com/aAAaqwq/AGI-Super-Team/tree/main/skills/genome-compare into .agents/skills/genome-compare/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-compare", then confirm the skill loads.

Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

skills CLI

$ npx skills add aAAaqwq/AGI-Super-Team --skill genome-compare -a cursor

Project install goes to .agents/skills/; add -g for ~/.cursor/skills/.

GitHub CLI

$ gh skill install aAAaqwq/AGI-Super-Team genome-compare --agent cursor

Project scope by default (.agents/skills/); add --scope user for a personal install.

Manual copy

$ git clone --depth 1 https://github.com/aAAaqwq/AGI-Super-Team.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/skills/genome-compare .cursor/skills/genome-compare && rm -rf skills-src

Use ~/.cursor/skills/ instead of .cursor/skills for a personal install.

Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/

Paste into Cursor

Install the "genome-compare" agent skill from https://github.com/aAAaqwq/AGI-Super-Team/tree/main/skills/genome-compare into .cursor/skills/genome-compare/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-compare", then confirm the skill loads.

Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

gemini skills install

$ gemini skills install https://github.com/aAAaqwq/AGI-Super-Team.git --path skills/genome-compare

--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.

skills CLI

$ npx skills add aAAaqwq/AGI-Super-Team --skill genome-compare -a gemini-cli

Project install goes to .agents/skills/; add -g for ~/.gemini/skills/.

GitHub CLI

$ gh skill install aAAaqwq/AGI-Super-Team genome-compare --agent gemini-cli

Project scope by default (.agents/skills/); add --scope user for a personal install.

Manual copy

$ git clone --depth 1 https://github.com/aAAaqwq/AGI-Super-Team.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/skills/genome-compare .gemini/skills/genome-compare && rm -rf skills-src

Use ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.

Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/

Paste into Gemini CLI

Install the "genome-compare" agent skill from https://github.com/aAAaqwq/AGI-Super-Team/tree/main/skills/genome-compare into .gemini/skills/genome-compare/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-compare", then confirm the skill loads.

Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

GitHub CLI

$ gh skill install aAAaqwq/AGI-Super-Team genome-compare

Installs for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).

skills CLI

$ npx skills add aAAaqwq/AGI-Super-Team --skill genome-compare -a github-copilot

Project install goes to .agents/skills/; add -g for ~/.copilot/skills/.

Manual copy

$ git clone --depth 1 https://github.com/aAAaqwq/AGI-Super-Team.git skills-src && mkdir -p .github/skills && cp -r skills-src/skills/genome-compare .github/skills/genome-compare && rm -rf skills-src

Use ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.

GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/

Paste into GitHub Copilot

Install the "genome-compare" agent skill from https://github.com/aAAaqwq/AGI-Super-Team/tree/main/skills/genome-compare into .github/skills/genome-compare/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-compare", then confirm the skill loads.

GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

skills CLI

$ npx skills add aAAaqwq/AGI-Super-Team --skill genome-compare -a opencode

OpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.

GitHub CLI

$ gh skill install aAAaqwq/AGI-Super-Team genome-compare --agent opencode

Project scope by default (.agents/skills/); add --scope user for a personal install.

Manual copy

$ git clone --depth 1 https://github.com/aAAaqwq/AGI-Super-Team.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/skills/genome-compare .opencode/skills/genome-compare && rm -rf skills-src

Use ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.

OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/

Paste into OpenCode

Install the "genome-compare" agent skill from https://github.com/aAAaqwq/AGI-Super-Team/tree/main/skills/genome-compare into .opencode/skills/genome-compare/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-compare", then confirm the skill loads.

OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.

Facts

Skill name: genome-compare
GitHub stars: 105
Used in: 1 other repo
Token cost: ~691 tokens
SKILL.md length: 263 words
Files: 5
Skills in repo: 152
Repo updated: Sep 27, 2026
First seen: Oct 7, 2026
Licence: MIT

At a glance

Compare your genome to George Church (PGP-1) and estimate ancestry composition

Works in 3 steps: Identity By State (IBS): Compare a… → Ancestry Composition: Estimate… → Chromosome Breakdown: Show…
Tasks that involve Bioinformatics
SKILL.md covers What You Do, Reference Genome, Input Formats and Demo, plus 4 more sections
Runs Python scripts from its folder; calls python

What it does

Genome Compare is an agent skill from aAAaqwq/AGI-Super-Team. Compare your genome to George Church (PGP-1) and estimate ancestry composition

Its SKILL.md is about 690 tokens, which your agent loads only when the skill is triggered. The skill folder holds 6 other files (for example `data/aims_panel.json`, `data/manuel_ancestry.json` and `genome_compare.py`).

It sits in Research & Science, covering Bioinformatics. The repository describes itself as: An installable, cross-framework AI organization: C-suite agents, expert subagents, curated skills, independent review, and one-command setup across 18 AI client/runtime adapters. The licence is MIT.

When your agent uses it

Tasks that involve Bioinformatics

Example prompts

“/genome-compare”

Requirements

Python 3

Workflow steps

3 steps, taken from the first numbered list in SKILL.md.

Identity By State (IBS): Compare a user's genome against George Church's public 23andMe data (PGP-1, hu43860C). Report how many SNPs…
Ancestry Composition: Estimate continental ancestry proportions (African, European, East Asian, South Asian, Americas) from…
Chromosome Breakdown: Show per-chromosome IBS scores and overlap counts.

What it can do on your machine

Read from SKILL.md and the folder at commit 331ecd3. It shows what the files ask for, not the result of running them.

Tool permissions
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Runs code
Ships script files (Python), which the agent can run.
Shell commands in SKILL.md call:
- python
From the folder's file list and the shell code blocks in SKILL.md.
Network
Links to these hosts (documentation or services it may open):
- pgp.med.harvard.edu
- doi.org
From URLs in SKILL.md, links to its own repository left out.
Credentials
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Genome Compare loads about 691 tokens when it runs. Until then it costs about 23 tokens; SKILL.md has 263 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it: ~23
When it runs · the whole SKILL.md, loaded when a task matches: ~691

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from aAAaqwq/AGI-Super-Team at commit 331ecd3, republished under its MIT licence (© aAAaqwq). 263 words, ~691 tokens.

Download SKILL.mdSave it as .claude/skills/genome-compare/SKILL.md (or your agent's skills folder). This skill also uses 4 other files; get the full folder from GitHub.

name: genome-compare
description: Compare your genome to George Church (PGP-1) and estimate ancestry composition
version: 0.1.0

Genome Comparator

You are the Genome Comparator, a specialised ClawBio skill for pairwise genome comparison and ancestry estimation.

What You Do

Identity By State (IBS): Compare a user's genome against George Church's public 23andMe data (PGP-1, hu43860C). Report how many SNPs overlap, how many are identical, and what the overall IBS score means in the context of genetic relationships.
Ancestry Composition: Estimate continental ancestry proportions (African, European, East Asian, South Asian, Americas) from ancestry-informative markers using an EM admixture algorithm.
Chromosome Breakdown: Show per-chromosome IBS scores and overlap counts.

Reference Genome

George Church (hu43860C) — the first participant in the Personal Genome Project. Professor of Genetics at Harvard Medical School. His 23andMe data (569,226 SNPs, CC0 public domain) is bundled in data/george_church_23andme.txt.gz.

Input Formats

23andMe raw data (.txt or .txt.gz)
Tab-separated: rsid, chromosome, position, genotype

Demo

In demo mode, the input is Manuel Corpas — participant uk6D0CFA in PGP-UK. His 23andMe genotype data (Corpasome) is CC0 public domain (figshare). This produces an IBS score of ~0.74, consistent with two unrelated Europeans.

CLI

bash

# Demo: Manuel Corpas vs George Church
python genome_compare.py --demo --output results/

# Your own data
python genome_compare.py --input your_23andme.txt --output results/

Output

report.md — Full markdown report with summary, IBS analysis, ancestry, methods
figures/chromosome_ibs.png — Per-chromosome IBS bar chart
figures/ancestry_pie.png — Ancestry composition pie chart
figures/ibs_context.png — IBS score on relationship spectrum gauge
figures/ancestry_comparison.png — Side-by-side ancestry comparison

Safety

All processing is local. Your genetic data never leaves your machine.
ClawBio is a research and educational tool. It is not a medical device.
Ancestry estimation is approximate — for clinical-grade results, use ADMIXTURE or professional services.

Citations

Church GM. The Personal Genome Project. Mol Syst Biol. 2005;1:2005.0030.
Corpas M. Crowdsourcing the Corpasome. Source Code Biol Med. 2013;8:13.

Files

SKILL.md and 4 other files in skills/genome-compare of aAAaqwq/AGI-Super-Team.

SKILL.md
data/aims_panel.json
data/manuel_ancestry.json
genome_compare.py
tests/test_genome_compare.py

Open the folder on GitHubat commit 331ecd3

Used in 1 other repository

We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in aAAaqwq/AGI-Super-Team, which our catalogue first saw on October 7, 2026.

NeverSight/learn-skills.devdata/skills-md/aaaaqwq/agi-super-team/genome-compare

Compare with similar skills

Genome Compare next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Genome Compare compared with similar skills
Skill	Stars	Used in	Tokens	Auto-check	Licence	Repo updated
Genome Compare this skillaAAaqwq/AGI-Super-Team	105	1 repos	~691	Automated safety check: Pass	MIT	11 days ago
Dbsnp Databasegoogle-deepmind/science-skills	3.2k	3 repos	~3.4k	Automated safety check: Notes	Apache-2.0	23 days ago
Metabolic Study Planneraiming-lab/AutoResearchClaw	15k	—	~1.9k	Automated safety check: Pass	MIT	1 mo ago
13C Metabolic Flux AnalysisK-Dense-AI/scientific-agent-skills	48k	1 repos	~3.2k	Automated safety check: Pass	MIT	3 days ago
Alphagenome Single Variant Analysisgoogle-deepmind/science-skills	3.2k	2 repos	~3k	Automated safety check: Notes	Apache-2.0	23 days ago
MFA Pipeline Orchestratoraiming-lab/AutoResearchClaw	15k	—	~923	Automated safety check: Pass	MIT	1 mo ago

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Questions about Genome Compare

What does Genome Compare do?

Compare your genome to George Church (PGP-1) and estimate ancestry composition. Genome Compare is an agent skill from aAAaqwq/AGI-Super-Team.

When should I use Genome Compare?

Genome Compare fits situations like: tasks that involve Bioinformatics.

How do I install Genome Compare in Claude Code?

Run `npx skills add aAAaqwq/AGI-Super-Team --skill genome-compare -a claude-code`. Or copy the skill folder (skills/genome-compare in aAAaqwq/AGI-Super-Team) into .claude/skills/genome-compare in your project. Claude Code loads it when a task matches its description.

How do I install Genome Compare in Codex?

Run `npx skills add aAAaqwq/AGI-Super-Team --skill genome-compare -a codex`. Or copy the skill folder (skills/genome-compare in aAAaqwq/AGI-Super-Team) into .agents/skills/genome-compare in your project. Codex loads it when a task matches its description.

Can I use Genome Compare in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add aAAaqwq/AGI-Super-Team --skill genome-compare -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/genome-compare, .gemini/skills/genome-compare, .github/skills/genome-compare and .opencode/skills/genome-compare in your project.

What does Genome Compare need to run?

Going by SKILL.md and its folder, Genome Compare needs Python for the scripts in its folder and the command-line tools its instructions call (python). Our summary lists: Python 3.

Does Genome Compare access the network?

SKILL.md names 2 domains. As links in the text: pgp.med.harvard.edu and doi.org. This is read from the text; nothing was executed.

Is Genome Compare safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Genome Compare use?

Genome Compare is published under the MIT licence (the repository's licence). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Genome Compare use?

About 691 tokens (SKILL.md is roughly 2.8k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Genome Compare?

Skills that share tags, products or a category with Genome Compare: Dbsnp Database (google-deepmind/science-skills, 3.2k stars), Metabolic Study Planner (aiming-lab/AutoResearchClaw, 15k stars), 13C Metabolic Flux Analysis (K-Dense-AI/scientific-agent-skills, 48k stars) and Alphagenome Single Variant Analysis (google-deepmind/science-skills, 3.2k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Genome Compare?

aAAaqwq (a GitHub user) maintains it in aAAaqwq/AGI-Super-Team, which has 105 GitHub stars. The repository holds 152 skills in this directory. The repository was last updated on September 27, 2026.

Source: aAAaqwq/AGI-Super-Team on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.

Install Genome Compare

Facts

At a glance

What it does

When your agent uses it

Example prompts

Requirements

Workflow steps

What it can do on your machine

Tool permissions

Runs code

Network

Credentials

Context cost

Safety

SKILL.md

Genome Comparator

What You Do

Reference Genome

Input Formats

Demo

CLI

Output

Safety

Citations

Files

Used in 1 other repository

Compare with similar skills

Similar skills

More from aAAaqwq/AGI-Super-Team

Related

Questions about Genome Compare