Exploratory Data Analysis
spacering-net/codeg
Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats.
Fit SimBiology model parameters to data — fitproblem, population NLME, virtual patients, and NCA.
Custom licenceAuto-check passed
Install Simbiology Fit Model
$ npx skills add matlab/matlab-agentic-toolkit --skill simbiology-fit-model -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install matlab/matlab-agentic-toolkit simbiology-fit-model --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/matlab/matlab-agentic-toolkit.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills-catalog/computational-biology/simbiology-fit-model .claude/skills/simbiology-fit-model && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "simbiology-fit-model" agent skill from https://github.com/matlab/matlab-agentic-toolkit/tree/main/skills-catalog/computational-biology/simbiology-fit-model into .claude/skills/simbiology-fit-model/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "simbiology-fit-model", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/matlab/matlab-agentic-toolkit/tree/main/skills-catalog/computational-biology/simbiology-fit-modelType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add matlab/matlab-agentic-toolkit --skill simbiology-fit-model -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install matlab/matlab-agentic-toolkit simbiology-fit-model --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/matlab/matlab-agentic-toolkit.git skills-src && mkdir -p .agents/skills && cp -r skills-src/skills-catalog/computational-biology/simbiology-fit-model .agents/skills/simbiology-fit-model && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "simbiology-fit-model" agent skill from https://github.com/matlab/matlab-agentic-toolkit/tree/main/skills-catalog/computational-biology/simbiology-fit-model into .agents/skills/simbiology-fit-model/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "simbiology-fit-model", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add matlab/matlab-agentic-toolkit --skill simbiology-fit-model -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install matlab/matlab-agentic-toolkit simbiology-fit-model --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/matlab/matlab-agentic-toolkit.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/skills-catalog/computational-biology/simbiology-fit-model .cursor/skills/simbiology-fit-model && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "simbiology-fit-model" agent skill from https://github.com/matlab/matlab-agentic-toolkit/tree/main/skills-catalog/computational-biology/simbiology-fit-model into .cursor/skills/simbiology-fit-model/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "simbiology-fit-model", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/matlab/matlab-agentic-toolkit.git --path skills-catalog/computational-biology/simbiology-fit-model--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add matlab/matlab-agentic-toolkit --skill simbiology-fit-model -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install matlab/matlab-agentic-toolkit simbiology-fit-model --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/matlab/matlab-agentic-toolkit.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/skills-catalog/computational-biology/simbiology-fit-model .gemini/skills/simbiology-fit-model && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "simbiology-fit-model" agent skill from https://github.com/matlab/matlab-agentic-toolkit/tree/main/skills-catalog/computational-biology/simbiology-fit-model into .gemini/skills/simbiology-fit-model/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "simbiology-fit-model", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install matlab/matlab-agentic-toolkit simbiology-fit-modelInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add matlab/matlab-agentic-toolkit --skill simbiology-fit-model -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/matlab/matlab-agentic-toolkit.git skills-src && mkdir -p .github/skills && cp -r skills-src/skills-catalog/computational-biology/simbiology-fit-model .github/skills/simbiology-fit-model && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "simbiology-fit-model" agent skill from https://github.com/matlab/matlab-agentic-toolkit/tree/main/skills-catalog/computational-biology/simbiology-fit-model into .github/skills/simbiology-fit-model/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "simbiology-fit-model", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add matlab/matlab-agentic-toolkit --skill simbiology-fit-model -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install matlab/matlab-agentic-toolkit simbiology-fit-model --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/matlab/matlab-agentic-toolkit.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/skills-catalog/computational-biology/simbiology-fit-model .opencode/skills/simbiology-fit-model && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "simbiology-fit-model" agent skill from https://github.com/matlab/matlab-agentic-toolkit/tree/main/skills-catalog/computational-biology/simbiology-fit-model into .opencode/skills/simbiology-fit-model/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "simbiology-fit-model", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
Facts
- Skill name
simbiology-fit-model- GitHub stars
- 1.1k
- Token cost
- ~4.2k tokens
- SKILL.md length
- 1,101 words
- Files
- 3 (incl. references)
- Skills in repo
- 151
- Repo updated
- First seen
- Licence
- Custom licence
At a glance
Fit SimBiology model parameters to data — fitproblem, population NLME, virtual patients, and NCA.
- Works in 7 steps: Use fitproblem for parameter estimation → Fitting requires groupedData, NOT a… → ResponseMap maps model outputs to data… → …
- Compute PK metrics
- SKILL.md covers When to Use, When NOT to Use, Must-Follow Rules and Decision Table, plus 5 more sections
- Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md
What it does
Simbiology Fit Model is an agent skill from matlab/matlab-agentic-toolkit. Fit SimBiology model parameters to data — fitproblem, population NLME, virtual patients, and NCA. Use when asked to fit, estimate, calibrate, or compute PK metrics.
Its SKILL.md is about 4.2k tokens, which your agent loads only when the skill is triggered. The skill folder holds 3 other files, including reference files (for example `manifest.yaml` and `references/nca-analysis-guidance.md`).
The repository describes itself as: The MATLAB Agentic Toolkit brings proven MATLAB capabilities to AI agents, making engineering and scientific workflows agent-ready.
When your agent uses it
- Compute PK metrics
- Tasks that involve Bioinformatics
Example prompts
- “/simbiology-fit-model”
Workflow steps
7 steps, taken from the step headings in SKILL.md.
- Use fitproblem for parameter estimation
- Fitting requires groupedData, NOT a plain table
- ResponseMap maps model outputs to data columns
- Always set bounds
- Use log transform for rate constants
- Error models for population fitting
- NCA requires sbioncaoptions object
What it can do on your machine
Read from SKILL.md and the folder at commit 69e71df. It shows what the files ask for, not the result of running them.
Tool permissions
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Runs code
No scripts in the folder and no shell commands in SKILL.md (its code samples are matlab).
From the folder's file list and the shell code blocks in SKILL.md.
Network
No URLs in SKILL.md.
From URLs in SKILL.md, links to its own repository left out.
Credentials
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
Context cost
Simbiology Fit Model loads about 4.2k tokens when it runs, and up to ~5.2k if it reads all its reference files. Until then it costs about 46 tokens; SKILL.md has 1,101 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
Safety
Auto-check passed
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.
SKILL.md
Its licence (Custom licence) doesn't allow us to republish the file, so here is its outline and opening line. It has 1,101 words (~4,218 tokens).
“Estimate parameters from data using fitproblem, fit population models with NLME, generate virtual patients, and compute NCA metrics.”
- name
- simbiology-fit-model
- license
- https://www.mathworks.com/content/dam/mathworks/license/pmrl/license.md
- metadata.author
- MathWorks
- metadata.version
- 2.0
Files
SKILL.md and 2 other files (references) in skills-catalog/computational-biology/simbiology-fit-model of matlab/matlab-agentic-toolkit.
- SKILL.md
- manifest.yaml
- references/nca-analysis-guidance.md
Open the folder on GitHubat commit 69e71df
Compare with similar skills
Simbiology Fit Model next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| Simbiology Fit Model this skillmatlab/matlab-agentic-toolkit | 1.1k | — | ~4.2k | Automated safety check: Pass | Custom licence | |
| Exploratory Data Analysisspacering-net/codeg | 3.9k | 14 repos | ~3.6k | Automated safety check: Pass | MIT | |
| Alphagenome Single Variant Analysisgoogle-deepmind/science-skills | 3.2k | 2 repos | ~3k | Automated safety check: Notes | Apache-2.0 | |
| 13C Metabolic Flux AnalysisK-Dense-AI/scientific-agent-skills | 48k | 1 repos | ~3.2k | Automated safety check: Pass | MIT | |
| Clinvar Databasegoogle-deepmind/science-skills | 3.2k | 2 repos | ~3.9k | Automated safety check: Notes | Apache-2.0 | |
| Metabolic Study Planneraiming-lab/AutoResearchClaw | 15k | — | ~1.9k | Automated safety check: Pass | MIT |
Similar skills
Alphagenome Single Variant Analysis
google-deepmind/science-skills
Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API.
13C Metabolic Flux Analysis
K-Dense-AI/scientific-agent-skills
Estimates reaction fluxes inside cells from steady-state carbon-13 labeling data with a bundled mfapy-based solver, and reports which fluxes the data pin down.
Clinvar Database
google-deepmind/science-skills
A skill your agent uses when needing clinical significance, pathogenicity classifications (e.g., Pathogenic, Benign, VUS), clinical evidence rationales, or finding "hard positive" benchmark controls…
Metabolic Study Planner
aiming-lab/AutoResearchClaw
Turns a broad metabolic modelling topic into a concrete, paper-shaped plan with organism, model, perturbations, metrics and figures before any FBA code is written.
Dbsnp Database
google-deepmind/science-skills
A skill your agent uses when you want to look up, map, and search for short genetic variants (SNPs, indels) in NCBI's dbSNP database.
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Questions about Simbiology Fit Model
What does Simbiology Fit Model do?
Fit SimBiology model parameters to data — fitproblem, population NLME, virtual patients, and NCA. Simbiology Fit Model is an agent skill from matlab/matlab-agentic-toolkit. Fit SimBiology model parameters to data — fitproblem, population NLME, virtual patients, and NCA.
When should I use Simbiology Fit Model?
Simbiology Fit Model fits situations like: compute PK metrics; tasks that involve Bioinformatics.
How do I install Simbiology Fit Model in Claude Code?
Run `npx skills add matlab/matlab-agentic-toolkit --skill simbiology-fit-model -a claude-code`. Or copy the skill folder (skills-catalog/computational-biology/simbiology-fit-model in matlab/matlab-agentic-toolkit) into .claude/skills/simbiology-fit-model in your project. Claude Code loads it when a task matches its description.
How do I install Simbiology Fit Model in Codex?
Run `npx skills add matlab/matlab-agentic-toolkit --skill simbiology-fit-model -a codex`. Or copy the skill folder (skills-catalog/computational-biology/simbiology-fit-model in matlab/matlab-agentic-toolkit) into .agents/skills/simbiology-fit-model in your project. Codex loads it when a task matches its description.
Can I use Simbiology Fit Model in Cursor, Gemini CLI or GitHub Copilot?
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add matlab/matlab-agentic-toolkit --skill simbiology-fit-model -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/simbiology-fit-model, .gemini/skills/simbiology-fit-model, .github/skills/simbiology-fit-model and .opencode/skills/simbiology-fit-model in your project.
What does Simbiology Fit Model need to run?
SKILL.md names no scripts, command-line tools or credentials: Simbiology Fit Model is instructions for the agent only.
Does Simbiology Fit Model access the network?
SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.
Is Simbiology Fit Model safe to install?
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.
What licence does Simbiology Fit Model use?
Simbiology Fit Model has a licence file (the repository's licence) that doesn't match a standard licence. Read it on GitHub before reusing the skill.
How many tokens does Simbiology Fit Model use?
About 4.2k tokens (SKILL.md is roughly 17k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 989 tokens, read only when the agent opens those files.
What are the alternatives to Simbiology Fit Model?
Skills that share tags, products or a category with Simbiology Fit Model: Exploratory Data Analysis (spacering-net/codeg, 3.9k stars), Alphagenome Single Variant Analysis (google-deepmind/science-skills, 3.2k stars), 13C Metabolic Flux Analysis (K-Dense-AI/scientific-agent-skills, 48k stars) and Clinvar Database (google-deepmind/science-skills, 3.2k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
Who maintains Simbiology Fit Model?
matlab (a GitHub organization) maintains it in matlab/matlab-agentic-toolkit, which has 1,147 GitHub stars. The repository holds 151 skills in this directory. The repository was last updated on October 8, 2026.
Source: matlab/matlab-agentic-toolkit on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.