Agent skill

Simbiology Build Model

by matlab in matlab/matlab-agentic-toolkit

Build, modify, and diagram SimBiology models — API reference, helper functions, and layout patterns.

Custom licenceAuto-check passed

Install Simbiology Build Model

skills CLI
$ npx skills add matlab/matlab-agentic-toolkit --skill simbiology-build-model -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install matlab/matlab-agentic-toolkit simbiology-build-model --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/matlab/matlab-agentic-toolkit.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills-catalog/computational-biology/simbiology-build-model .claude/skills/simbiology-build-model && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
simbiology-build-model
GitHub stars
1.1k
Token cost
~5.2k tokens
SKILL.md length
1,733 words
Files
23 (incl. scripts, references)
Skills in repo
151
Repo updated
First seen
Licence
Custom licence

At a glance

Build, modify, and diagram SimBiology models — API reference, helper functions, and layout patterns.

  • Works in 8 steps: Add helper scripts to the MATLAB path… → Only open the Builder when needed → Model construction uses standard… → …
  • Editing models programmatically
  • SKILL.md covers When to Use, When NOT to Use, Must-Follow Rules and Helper Functions (scripts/), plus 2 more sections
  • Tasks that involve Bioinformatics

What it does

Simbiology Build Model is an agent skill from matlab/matlab-agentic-toolkit. Build, modify, and diagram SimBiology models — API reference, helper functions, and layout patterns. Use when constructing or editing models programmatically or visually.

Its SKILL.md is about 5.2k tokens, which your agent loads only when the skill is triggered. The skill folder holds 24 other files, including scripts and reference files (for example `manifest.yaml`, `references/api-cheatsheet-guidance.md` and `references/app-lifecycle-guidance.md`).

The repository describes itself as: The MATLAB Agentic Toolkit brings proven MATLAB capabilities to AI agents, making engineering and scientific workflows agent-ready.

When your agent uses it

  • Editing models programmatically
  • Tasks that involve Bioinformatics

Example prompts

  • “/simbiology-build-model”

Workflow steps

8 steps, taken from the step headings in SKILL.md.

  1. Add helper scripts to the MATLAB path first
  2. Only open the Builder when needed
  3. Model construction uses standard SimBiology API
  4. Write reactions in the biological forward direction
  5. Always use qualified names for species and reaction-scoped parameters
  6. Use modern property names (Value, Units, Constant)
  7. Close Builder and Analyzer before sbioreset
  8. Diagram rules (only when user requests a diagram)

What it can do on your machine

Read from SKILL.md and the folder at commit 69e71df. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships 10 files in scripts/, which the agent can run.

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Simbiology Build Model loads about 5.2k tokens when it runs, and up to ~15k if it reads all its reference files. Until then it costs about 48 tokens; SKILL.md has 1,733 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~48
When it runs · the whole SKILL.md, loaded when a task matches
~5.2k
With references · SKILL.md plus every file in references/, read only if the agent opens them
~15k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); the scripts in this folder are not scanned.

SKILL.md

Its licence (Custom licence) doesn't allow us to republish the file, so here is its outline and opening line. It has 1,733 words (~5,248 tokens).

“API reference, helper functions, and patterns for building, modifying, and diagramming SimBiology models. Works in all MATLAB environments (desktop, headless, batch, remote). Diagram/layout features require the Model Builder app and are activated only when the user requests visual output.”

— opening of SKILL.md by matlab, Custom licence
name
simbiology-build-model
license
https://www.mathworks.com/content/dam/mathworks/license/pmrl/license.md
metadata.author
MathWorks
metadata.version
2.0

Read the full SKILL.md on GitHub

Files

SKILL.md and 22 other files (scripts, references) in skills-catalog/computational-biology/simbiology-build-model of matlab/matlab-agentic-toolkit.

  • SKILL.md
  • manifest.yaml
  • references/api-cheatsheet-guidance.md
  • references/app-lifecycle-guidance.md
  • references/diagram-styling-guidance.md
  • references/evacuation-procedure-guidance.md
  • references/layout-strategy-guidance.md
  • references/pbpk-layout-guidance.md
  • references/pk-library-guidance.md
  • scripts/addAndPositionCompartment.p
  • scripts/buildLayoutContext.p
  • scripts/checkDiagramLayout.p
  • scripts/computeSafeReactionPosition.p
  • scripts/getModelByUUID.p
  • scripts/isAppOpen.p
  • scripts/lineIntersectsRect.p
  • scripts/loadViaBuilder.p
  • scripts/openLiveBuilder.p
  • scripts/positionAncillaryBlocks.p
  • … and 4 more

Open the folder on GitHubat commit 69e71df

Compare with similar skills

Simbiology Build Model next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Simbiology Build Model compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Simbiology Build Model this skillmatlab/matlab-agentic-toolkit1.1k—~5.2kAutomated safety check: PassCustom licence
Exploratory Data Analysisspacering-net/codeg3.9k14 repos~3.6kAutomated safety check: PassMIT
Alphagenome Single Variant Analysisgoogle-deepmind/science-skills3.2k2 repos~3kAutomated safety check: NotesApache-2.0
13C Metabolic Flux AnalysisK-Dense-AI/scientific-agent-skills48k1 repos~3.2kAutomated safety check: PassMIT
Clinvar Databasegoogle-deepmind/science-skills3.2k2 repos~3.9kAutomated safety check: NotesApache-2.0
Metabolic Study Planneraiming-lab/AutoResearchClaw15k—~1.9kAutomated safety check: PassMIT

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Questions about Simbiology Build Model

What does Simbiology Build Model do?

Build, modify, and diagram SimBiology models — API reference, helper functions, and layout patterns. Simbiology Build Model is an agent skill from matlab/matlab-agentic-toolkit. Build, modify, and diagram SimBiology models — API reference, helper functions, and layout patterns.

When should I use Simbiology Build Model?

Simbiology Build Model fits situations like: editing models programmatically; tasks that involve Bioinformatics.

How do I install Simbiology Build Model in Claude Code?

Run `npx skills add matlab/matlab-agentic-toolkit --skill simbiology-build-model -a claude-code`. Or copy the skill folder (skills-catalog/computational-biology/simbiology-build-model in matlab/matlab-agentic-toolkit) into .claude/skills/simbiology-build-model in your project. Claude Code loads it when a task matches its description.

How do I install Simbiology Build Model in Codex?

Run `npx skills add matlab/matlab-agentic-toolkit --skill simbiology-build-model -a codex`. Or copy the skill folder (skills-catalog/computational-biology/simbiology-build-model in matlab/matlab-agentic-toolkit) into .agents/skills/simbiology-build-model in your project. Codex loads it when a task matches its description.

Can I use Simbiology Build Model in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add matlab/matlab-agentic-toolkit --skill simbiology-build-model -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/simbiology-build-model, .gemini/skills/simbiology-build-model, .github/skills/simbiology-build-model and .opencode/skills/simbiology-build-model in your project.

What does Simbiology Build Model need to run?

SKILL.md names no scripts, command-line tools or credentials: Simbiology Build Model is instructions for the agent only.

Does Simbiology Build Model access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Simbiology Build Model safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. The check reads SKILL.md only: the scripts in the folder are not scanned, so read them before running anything.

What licence does Simbiology Build Model use?

Simbiology Build Model has a licence file (the repository's licence) that doesn't match a standard licence. Read it on GitHub before reusing the skill.

How many tokens does Simbiology Build Model use?

About 5.2k tokens (SKILL.md is roughly 21k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 9.6k tokens, read only when the agent opens those files.

What are the alternatives to Simbiology Build Model?

Skills that share tags, products or a category with Simbiology Build Model: Exploratory Data Analysis (spacering-net/codeg, 3.9k stars), Alphagenome Single Variant Analysis (google-deepmind/science-skills, 3.2k stars), 13C Metabolic Flux Analysis (K-Dense-AI/scientific-agent-skills, 48k stars) and Clinvar Database (google-deepmind/science-skills, 3.2k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Simbiology Build Model?

matlab (a GitHub organization) maintains it in matlab/matlab-agentic-toolkit, which has 1,144 GitHub stars. The repository holds 151 skills in this directory. The repository was last updated on October 8, 2026.

Source: matlab/matlab-agentic-toolkit on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.