Dbsnp Database
google-deepmind/science-skills
A skill your agent uses when you want to look up, map, and search for short genetic variants (SNPs, indels) in NCBI's dbSNP database.
Query IGVF Catalog for regulatory element–gene associations within a genomic region, including association scores, element types, and biosample context.
$ npx skills add InternScience/scp --skill region-gene-elements -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install InternScience/scp region-gene-elements --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/region-gene-elements .claude/skills/region-gene-elements && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "region-gene-elements" agent skill from https://github.com/InternScience/scp/tree/main/skills/region-gene-elements into .claude/skills/region-gene-elements/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "region-gene-elements", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/InternScience/scp/tree/main/skills/region-gene-elementsType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add InternScience/scp --skill region-gene-elements -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install InternScience/scp region-gene-elements --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .agents/skills && cp -r skills-src/skills/region-gene-elements .agents/skills/region-gene-elements && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "region-gene-elements" agent skill from https://github.com/InternScience/scp/tree/main/skills/region-gene-elements into .agents/skills/region-gene-elements/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "region-gene-elements", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add InternScience/scp --skill region-gene-elements -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install InternScience/scp region-gene-elements --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/skills/region-gene-elements .cursor/skills/region-gene-elements && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "region-gene-elements" agent skill from https://github.com/InternScience/scp/tree/main/skills/region-gene-elements into .cursor/skills/region-gene-elements/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "region-gene-elements", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/InternScience/scp.git --path skills/region-gene-elements--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add InternScience/scp --skill region-gene-elements -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install InternScience/scp region-gene-elements --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/skills/region-gene-elements .gemini/skills/region-gene-elements && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "region-gene-elements" agent skill from https://github.com/InternScience/scp/tree/main/skills/region-gene-elements into .gemini/skills/region-gene-elements/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "region-gene-elements", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install InternScience/scp region-gene-elementsInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add InternScience/scp --skill region-gene-elements -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .github/skills && cp -r skills-src/skills/region-gene-elements .github/skills/region-gene-elements && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "region-gene-elements" agent skill from https://github.com/InternScience/scp/tree/main/skills/region-gene-elements into .github/skills/region-gene-elements/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "region-gene-elements", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add InternScience/scp --skill region-gene-elements -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install InternScience/scp region-gene-elements --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/InternScience/scp.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/skills/region-gene-elements .opencode/skills/region-gene-elements && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "region-gene-elements" agent skill from https://github.com/InternScience/scp/tree/main/skills/region-gene-elements into .opencode/skills/region-gene-elements/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "region-gene-elements", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
region-gene-elementsQuery IGVF Catalog for regulatory element–gene associations within a genomic region, including association scores, element types, and biosample context.
Region Gene Elements is an agent skill from InternScience/scp. Query IGVF Catalog for regulatory element–gene associations within a genomic region, including association scores, element types, and biosample context.
Its SKILL.md is about 750 tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.
It sits in Research & Science, covering Bioinformatics. The licence is MIT.
Read from SKILL.md and the folder at commit cea5398. It shows what the files ask for, not the result of running them.
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
No scripts in the folder and no shell commands in SKILL.md (its code samples are tex and python).
From the folder's file list and the shell code blocks in SKILL.md.
Hosts in commands or code, which the agent is likely to contact:
api.catalogkg.igvf.orgFrom URLs in SKILL.md, links to its own repository left out.
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
Region Gene Elements loads about 747 tokens when it runs. Until then it costs about 43 tokens; SKILL.md has 12 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.
The full file from InternScience/scp at commit cea5398, republished under its MIT licence (© InternScience). 12 words, ~747 tokens.
.claude/skills/region-gene-elements/SKILL.md (or your agent's skills folder).Query IGVF Catalog API to find regulatory-element-to-gene associations within a genomic region.
Database: IGVF Catalog (https://api.catalogkg.igvf.org/)
API: GET https://api.catalogkg.igvf.org/api/genomic-elements/genes
Args:
region (str): Required. Genomic region, e.g. "chr1:903900-904900"
organism (str): Default "Homo sapiens"
source_annotation (str, optional): e.g. "enhancer", "intergenic"
region_type (str, optional): e.g. "accessible dna elements", "tested elements"
source (str, optional): e.g. "ENCODE_EpiRaction"
method (str, optional): e.g. "CRISPR FACS screen"
biosample_name (str, optional): e.g. "placenta"
verbose (bool): true=返回完整信息, false=精简 (default false)
page (int): 0-based page
limit (int): 每页条目数, 最大 500
Return (list of dicts), each item contains:
- score (float): 调控元件与基因的关联分数
- source (str): 数据来源 (e.g. "ENCODE")
- source_url (str): 来源链接
- genomic_element (dict):
- chr, start, end: 调控元件基因组坐标
- source_annotation: 元件注释类型 (intergenic, enhancer, promoter 等)
- type: 元件类型 (accessible dna elements, tested elements 等)
- gene (dict):
- _id: Ensembl Gene ID (e.g. "ENSG00000187634")
- name: 基因名 (e.g. "SAMD11")
- chr, start, end, strand: 基因坐标
- gene_type: 基因类型 (protein_coding, lncRNA 等)
- hgnc: HGNC ID (e.g. "HGNC:28706")
- entrez: Entrez ID (e.g. "ENTREZ:148398")
- biosample (str): 来源生物样本 (e.g. "natural killer cell...")
- method (str): 实验方法 (e.g. "CRISPR FACS screen")import requests
region = "chr1:903900-904900"
url = "https://api.catalogkg.igvf.org/api/genomic-elements/genes"
params = {
"region": region,
"organism": "Homo sapiens",
"verbose": "true",
"page": 0,
}
resp = requests.get(url, params=params, timeout=30).json()
print(f"[IGVF] 区域 {region} 内调控元件-基因关联: {len(resp)} 条")
for i, item in enumerate(resp[:10]):
gene = item.get("gene", {})
elem = item.get("genomic_element", {})
print(f"\n [{i+1}] 基因: {gene.get('name', 'N/A')} ({gene.get('_id', '')})")
print(f" 基因坐标: {gene.get('chr')}:{gene.get('start')}-{gene.get('end')} ({gene.get('strand')})")
print(f" 基因类型: {gene.get('gene_type', '')}")
print(f" 调控元件: {elem.get('chr')}:{elem.get('start')}-{elem.get('end')}")
print(f" 元件类型: {elem.get('type', '')} ({elem.get('source_annotation', '')})")
print(f" 关联分数: {item.get('score', 'N/A')}")
print(f" 来源: {item.get('source', '')}, 方法: {item.get('method', '')}")
print(f" 样本: {item.get('biosample', '')[:60]}")© InternScience, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file
Just SKILL.md in skills/region-gene-elements of InternScience/scp.
Open the folder on GitHubat commit cea5398
We found 2 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in InternScience/scp, which our catalogue first saw on October 7, 2026.
Region Gene Elements next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| Region Gene Elements this skillInternScience/scp | 169 | 1 repos | ~747 | Automated safety check: Pass | MIT | |
| Dbsnp Databasegoogle-deepmind/science-skills | 3.2k | 3 repos | ~3.4k | Automated safety check: Notes | Apache-2.0 | |
| Metabolic Study Planneraiming-lab/AutoResearchClaw | 15k | — | ~1.9k | Automated safety check: Pass | MIT | |
| 13C Metabolic Flux AnalysisK-Dense-AI/scientific-agent-skills | 48k | 1 repos | ~3.2k | Automated safety check: Pass | MIT | |
| Alphagenome Single Variant Analysisgoogle-deepmind/science-skills | 3.2k | 2 repos | ~3k | Automated safety check: Notes | Apache-2.0 | |
| MFA Pipeline Orchestratoraiming-lab/AutoResearchClaw | 15k | — | ~923 | Automated safety check: Pass | MIT |
google-deepmind/science-skills
A skill your agent uses when you want to look up, map, and search for short genetic variants (SNPs, indels) in NCBI's dbSNP database.
aiming-lab/AutoResearchClaw
Turns a broad metabolic modelling topic into a concrete, paper-shaped plan with organism, model, perturbations, metrics and figures before any FBA code is written.
K-Dense-AI/scientific-agent-skills
Estimates reaction fluxes inside cells from steady-state carbon-13 labeling data with a bundled mfapy-based solver, and reports which fluxes the data pin down.
google-deepmind/science-skills
Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API.
aiming-lab/AutoResearchClaw
Runs a metabolic flux analysis from model loading to phenotype prediction and figures by handing work to four sub-agents in sequence.
xuzhougeng/wisp-science
A skill your agent uses when designing, reviewing, or implementing single-cell RNA-seq QC in Python or R with a human-in-the-loop, data-driven approach.
InternScience/scp
Given an rsID, query multiple databases (dbSNP, FAVOR, GWAS Catalog, ClinVar, gnomAD, PharmGKB, ClinGen) for comprehensive annotation.
InternScience/scp
Use ESMFold model to predict 3D structure of the input protein sequence.
InternScience/scp
Given a protein sequence and its structure, employ ProSST model to predict mutation effects and obtain the top-k mutated sequences.
InternScience/scp
Calculate atmospheric parameters including Coriolis parameter, geostrophic wind, heat index, potential temperature, and dewpoint for meteorology and climate science.
InternScience/scp
Search biomedical literature and web content using Tavily search engine for research and clinical information.
InternScience/scp
Calculate buoyancy forces and acceleration for fluid mechanics and hydrodynamics analysis.
Categories
Query IGVF Catalog for regulatory element–gene associations within a genomic region, including association scores, element types, and biosample context. Region Gene Elements is an agent skill from InternScience/scp. Query IGVF Catalog for regulatory element–gene associations within a genomic region, including association scores, element types, and biosample context.
Region Gene Elements fits situations like: tasks that involve Bioinformatics.
Run `npx skills add InternScience/scp --skill region-gene-elements -a claude-code`. Or copy the skill folder (skills/region-gene-elements in InternScience/scp) into .claude/skills/region-gene-elements in your project. Claude Code loads it when a task matches its description.
Run `npx skills add InternScience/scp --skill region-gene-elements -a codex`. Or copy the skill folder (skills/region-gene-elements in InternScience/scp) into .agents/skills/region-gene-elements in your project. Codex loads it when a task matches its description.
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add InternScience/scp --skill region-gene-elements -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/region-gene-elements, .gemini/skills/region-gene-elements, .github/skills/region-gene-elements and .opencode/skills/region-gene-elements in your project.
SKILL.md names no scripts, command-line tools or credentials: Region Gene Elements is instructions for the agent only. Our summary lists: Python 3.
SKILL.md names 1 domain. In commands or code: api.catalogkg.igvf.org; the agent is likely to contact it when it follows the instructions. This is read from the text; nothing was executed.
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.
Region Gene Elements is published under the MIT licence (declared in SKILL.md). It allows redistribution, so the full SKILL.md is shown on this page.
About 747 tokens (SKILL.md is roughly 3k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.
Skills that share tags, products or a category with Region Gene Elements: Dbsnp Database (google-deepmind/science-skills, 3.2k stars), Metabolic Study Planner (aiming-lab/AutoResearchClaw, 15k stars), 13C Metabolic Flux Analysis (K-Dense-AI/scientific-agent-skills, 48k stars) and Alphagenome Single Variant Analysis (google-deepmind/science-skills, 3.2k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
InternScience (a GitHub organization) maintains it in InternScience/scp, which has 169 GitHub stars. The repository holds 73 skills in this directory. The repository was last updated on June 3, 2026.
Source: InternScience/scp on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.