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Agent skill

Bio Tcr Bcr Analysis Mixcr Analysis

by GPTomics in GPTomics/bioSkills

Align V(D)J reads and assemble TCR/BCR clonotypes with MiXCR, driven by a chemistry-matched preset.

MITAuto-check passedResearch & Science

Install Bio Tcr Bcr Analysis Mixcr Analysis

skills CLI
$ npx skills add GPTomics/bioSkills --skill bio-tcr-bcr-analysis-mixcr-analysis -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install GPTomics/bioSkills bio-tcr-bcr-analysis-mixcr-analysis --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/GPTomics/bioSkills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/tcr-bcr-analysis/mixcr-analysis .claude/skills/bio-tcr-bcr-analysis-mixcr-analysis && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
bio-tcr-bcr-analysis-mixcr-analysis
GitHub stars
1.2k
Used in
1 other repo
Token cost
~4.1k tokens
SKILL.md length
1,892 words
Files
3
Skills in repo
559
Repo updated
First seen
Licence
MIT

At a glance

Align V(D)J reads and assemble TCR/BCR clonotypes with MiXCR, driven by a chemistry-matched preset.

  • Choosing/auditing the preset for a library (5RACE/template-switch vs multiplex-primer amplicon - rigid vs floating boundaries
  • SKILL.md covers Version Compatibility, The governing principle: the…, Licensing gate (do this first,… and Preset selection by library type, plus 8 more sections
  • Runs Shell scripts from its folder
  • RNA vs gDNA - --rna/--dna

What it does

Bio Tcr Bcr Analysis Mixcr Analysis is an agent skill from GPTomics/bioSkills. Align V(D)J reads and assemble TCR/BCR clonotypes with MiXCR, driven by a chemistry-matched preset. Use when choosing/auditing the preset for a library (5'RACE/template-switch vs multiplex-primer amplicon - rigid vs floating boundaries; RNA vs gDNA - --rna/--dna; bulk vs 10x single-cell; UMI vs no-UMI - tag pattern and barcode collapse; kit presets Takara/NEBNext/QIAseq/BD/MiLaboratory); assembling clonotypes by CDR3 vs VDJRegion; setting the reads-vs-UMI-vs-cell quantitation denominator; exporting native MiXCR…

Its SKILL.md is about 4.1k tokens, which your agent loads only when the skill is triggered. The skill folder holds 3 other files (for example `examples/mixcr_workflow.sh` and `usage-guide.md`).

It sits in Research & Science, covering Bioinformatics and CSV and tabular files. The repository describes itself as: a set of SKILLS.md for doing bioinformatics with agents like claude code. The licence is MIT.

When your agent uses it

  • Choosing/auditing the preset for a library (5RACE/template-switch vs multiplex-primer amplicon - rigid vs floating boundaries
  • RNA vs gDNA - --rna/--dna
  • Bulk vs 10x single-cell
  • UMI vs no-UMI - tag pattern and barcode collapse

Example prompts

  • “/bio-tcr-bcr-analysis-mixcr-analysis”

Requirements

  • A Bash shell
  • Docker

What it can do on your machine

Read from SKILL.md and the folder at commit d91ed3d. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships script files (Shell), which the agent can run.

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    Links to these hosts (documentation or services it may open):

    • mixcr.com

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Bio Tcr Bcr Analysis Mixcr Analysis loads about 4.1k tokens when it runs. Until then it costs about 216 tokens; SKILL.md has 1,892 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~216
When it runs · the whole SKILL.md, loaded when a task matches
~4.1k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from GPTomics/bioSkills at commit d91ed3d, republished under its MIT licence (© GPTomics). 1,892 words, ~4,106 tokens.

Download SKILL.mdSave it as .claude/skills/bio-tcr-bcr-analysis-mixcr-analysis/SKILL.md (or your agent's skills folder). This skill also uses 2 other files; get the full folder from GitHub.
name
bio-tcr-bcr-analysis-mixcr-analysis
description
Align V(D)J reads and assemble TCR/BCR clonotypes with MiXCR, driven by a chemistry-matched preset. Use when choosing/auditing the preset for a library (5'RACE/template-switch vs multiplex-primer amplicon -> rigid vs floating boundaries; RNA vs gDNA -> --rna/--dna; bulk vs 10x single-cell; UMI vs no-UMI -> tag pattern and barcode collapse; kit presets Takara/NEBNext/QIAseq/BD/MiLaboratory); assembling clonotypes by CDR3 vs VDJRegion; setting the reads-vs-UMI-vs-cell quantitation denominator; exporting native MiXCR fields vs AIRR rearrangement TSV for downstream Immcantation/scirpy/VDJtools; and running alignment/chain-usage QC. Keywords: MiXCR, analyze, align, refineTagsAndSort, assemblePartial, assemble, assembleCells, exportClones, exportAirr, exportQc, CDR3, V(D)J, clonotype, UMI, cell barcode, 10x VDJ, license.
tool_type
cli
primary_tool
MiXCR

Version Compatibility

Reference examples tested with: MiXCR 4.7+ (Java 17)

Before using code patterns, verify installed versions match. If versions differ:

  • CLI: mixcr --version (also prints the JVM) then mixcr <command> --help to confirm flags

If a command errors with an unknown-flag, unknown-preset, or missing-license message, run mixcr <command> --help and mixcr exportPreset --preset-name <name> and adapt rather than retrying.

Note: MiXCR 4.x is a rearchitecture of 3.x. The hand-built mixcr analyze amplicon/analyze shotgun pipelines are GONE, replaced by mixcr analyze <preset>; correctAndSortTags became refineTagsAndSort; AIRR export moved to a dedicated mixcr exportAirr. Current 4.x needs Java 17 and an activated license (see the licensing gate below). Any 3.x tutorial is stale.

MiXCR Analysis

"Extract TCR/BCR clonotypes from my sequencing data" -> align raw reads to V/D/J/C germline, collapse molecules/cells by barcode, and assemble reads into clonotypes keyed on CDR3 + V + J.

  • CLI: mixcr analyze <preset> runs the whole ordered pipeline; the underlying stages (align -> refineTagsAndSort -> assemblePartial/extend -> assemble -> assembleCells -> exportClones/exportAirr -> qc) can be run by hand for control.

The governing principle: the preset IS the analysis, and the wrong one fails silently

In MiXCR 4.x there is no default-correct pipeline. Correctness is ~90% preset choice plus library-chemistry match. mixcr analyze <preset> expands the preset into an ordered stage list encoding material (RNA vs DNA), 5'/3' alignment-boundary behavior (rigid vs floating), the barcode tag pattern, the assembling feature, and species defaults. The wrong preset does NOT raise an error -- it emits plausible-but-wrong clonotypes: a mismatched RNA/DNA model or boundary model mis-places V/J boundaries and truncates CDR3; a UMI kit run without a tag pattern skips barcode collapse and inflates diversity with PCR/sequencing artifacts. Because the failure is silent, the load-bearing skill is choosing and AUDITING the preset. Dump exactly what a preset does with mixcr exportPreset --preset-name <name> (full resolved parameter YAML), and confirm chemistry with mixcr exportQc align/chainUsage after the run. A clonotype is an analyst choice, not a fact: it is CDR3 (+ V + J) at a chosen boundary (assembling feature), counted in a chosen denominator (reads vs UMIs vs cells) -- every downstream number depends on these.

Licensing gate (do this first, or every run fails)

MiXCR 4.x refuses to run any analysis command until a license is activated -- the single most common reason a copied 3.x recipe fails today. Academic/non-profit use is free (obtain a key at platforma.bio/getlicense); for-profit use needs a business license. Activate by any one of:

  • mixcr activate-license then paste the key (interactive).
  • Place mi.license (or ~/.mi.license) in ~/, next to mixcr.jar, or next to the executable.
  • Set MI_LICENSE=<key content> or MI_LICENSE_FILE=/path/mi.license (best for HPC/Docker/CI).

MiXCR also validates the key over the internet periodically. On air-gapped or firewalled compute nodes, whitelist IPv4 75.2.96.100 and 99.83.215.63 (and the corresponding IPv6) or arrange an offline license, or a job silently stalls waiting on egress.

Preset selection by library type

The preset must match the exact wet-lab chemistry. Inspect the built-in list with mixcr exportPreset and the docs; verify current names against mixcr analyze --help since MiLaboratories occasionally renames presets between minor releases.

Library / chemistryPreset (verified 4.7)Material5' boundaryUMI/barcodeBiology consequence if mismatched
5'RACE / template-switch bulk (e.g. SMARTer)kit preset, or generic-amplicon/-with-umi with --rigid-left-alignment-boundary--rnaRIGID (5' set by template-switch oligo)kit UMI or --tag-patternFloating-left on RACE trims real 5' V sequence; missing tag pattern skips UMI collapse
Multiplex-primer amplicon (V/J or V/C primers)kit preset, or generic-amplicon with --floating-left-alignment-boundary--rna or --dnaFLOATING on the primer sideas designedRigid boundary counts primer bases as germline mismatch -> wrong V call, truncated CDR3
gDNA multiplex (genomic template)--dna variant preset--dna (include introns)floating on primer sideusually none--rna on gDNA drops intron-containing alignments; gDNA count approximates cell count
Bulk RNA-seq mining (non-targeted)rna-seq--rnan/a (fragmented)noneNeeds assemblePartial x2 + extend; judged by absolute yield, not % aligned
10x single-cell V(D)J (TCR+BCR)10x-sc-xcr-vdjpreset-setpreset-setCELL+UMI (preset)Missing cell/UMI pattern -> no pairing, fake diversity; count CELLS not reads
10x 5' GEX repertoire mining10x-sc-5gexpreset-setpreset-setCELL+UMIShallow repertoire mined from GEX; not a substitute for enriched VDJ
Takara SMARTer human TCR/BCRtakara-human-rna-tcr-umi-smarter-v2, takara-human-rna-bcr-umi-smarter, ...-smartseq--rnaRIGID (template-switch)12nt UMI (preset)Uses the correct RACE boundary + UMI pattern automatically
NEBNext immune-seqneb-human-rna-xcr-umi-nebnext (neb-mouse-...)--rnapreset-setUMI (preset)xcr = both TCR and BCR in one preset
QIAseq immuneqiagen-human-rna-tcr-umi-qiaseq (...-mouse-...)--rnapreset-setUMI (preset)--
BD Rhapsody single-cellbd-human-sc-xcr-rhapsody-cdr3, bd-sc-xcr-rhapsody-full-lengthpreset-setpreset-setCELL+UMIfull-length variant enables SHM/contig work
MiLaboratories kitsmilab-human-rna-tcr-umi-race, milab-human-rna-tcr-umi-multiplex, milab-human-dna-tcr-multiplex, ...per nameper nameper namename decodes <vendor>-<species>-<rna/dna>-<chain>-[umi]-<protocol>

For generic-* presets --species <hsa|mmu|...> is REQUIRED (forgetting it fails or misaligns). xcr presets cover TCR and BCR together; single-chain presets (trb, ig) cover one locus. For gamma-delta (TRG/TRD), use the same generic/kit presets and restrict chains at export with -c TRG / -c TRD (or a gd-specific kit preset if the wet-lab kit targets gd); note that a gd repertoire is invisible if the library only primed alpha-beta.

Pipeline stages and where each one fails

mixcr analyze <preset> R1.fastq.gz R2.fastq.gz out_prefix runs the ordered stages below; the preset is embedded in the binary .vdjca/.clns files so hand-run commands only name the preset on align.

StageCommandPurposeCommon failure
Alignmixcr align -p <preset> --species hsa ...Reads -> V/D/J/C germline; extract barcodes if tag pattern setLow alignment rate: wrong species/material/boundaries, untrimmed primers, reads too short to span CDR3
Refine tagsmixcr refineTagsAndSortUMI + cell-barcode error correction and sortSkipped on a UMI library -> barcode errors become fake clonotypes; memory-heavy (~32 GB on large single-cell)
Assemble partialmixcr assemblePartial (run x2)Overlap fragmented mates that each cover part of CDR3 (RNA-seq/10x)Needs align --keep-non-CDR3-alignments first; on amplicon reads that already span CDR3 it is wasted
Extendmixcr extendImpute unambiguous missing V/J germline endsSafe for TCR; on BCR can fabricate germline over SHM-mutated ends
Assemblemixcr assembleCollapse alignments into clonotypes by the assembling feature; PCR/error correction, UMI consensusWrong assembling feature merges/splits clones; low-quality CDR3 filtered
Assemble cellsmixcr assembleCellsSingle-cell: group per-chain clones by CELL barcode into paired cellsNeeds cell tags; barcode contamination -> mispaired cells
Exportmixcr exportClones / mixcr exportAirrWrite clonotype TSV (native or AIRR)Native field-name mistakes; forgetting -c/--chains; not filtering non-productive
QCmixcr qc, mixcr exportQc align/chainUsageAlignment rate, chain composition, tag coverageNot run -> silent quality problems pass downstream

From MiXCR 4.7, presets that do not intrinsically define an assembling feature REQUIRE --assemble-clonotypes-by <feature> (e.g. CDR3, VDJRegion); older tutorials that omit it now error. CDR3 is the robust default on short reads; VDJRegion needs reads/contigs spanning V-through-J and keeps SHM variants separate (useful for BCR full-length).

The quantitation denominator: reads vs UMIs vs cells

Clonotype abundance is only meaningful relative to the chemistry. Report the right unit or reintroduce the bias the chemistry was meant to remove:

  • Non-UMI bulk: abundance = readCount (cloneCount is an alias). PCR-amplification biased -- not a molecule count.
  • UMI bulk: after refineTagsAndSort, report uniqueMoleculeCount (generic form uniqueTagCount Molecule), NOT reads. Reporting reads on a UMI library re-adds the amplification bias the UMIs removed.
  • Single-cell: the unit is the CELL (uniqueTagCount Cell / cellGroup), not reads or UMIs.
Show full SKILL.md (722 more words)Show less

Export: native MiXCR fields vs AIRR

MiXCR's native export headers are NOT AIRR or VDJtools names. Downstream renaming to a chosen schema is a user-side step; the field names to select from MiXCR are its own.

bash
mixcr exportClones -c TRB \
    -cloneId -readCount -readFraction -uniqueMoleculeCount \
    -nSeqCDR3 -aaSeqCDR3 -bestVGene -bestJGene -allVHitsWithScore -isProductive VRegion \
    clones.clns clones_TRB.tsv

Key native fields: cloneId, readCount/readFraction (aliases cloneCount/cloneFraction), uniqueMoleculeCount, nSeqCDR3/aaSeqCDR3 (CDR3 nt/aa -- the headline fields), bestVGene/bestJGene/bestCGene (gene-level), bestVHit (allele-level best), allVHitsWithScore (full hit list), isProductive <feature>. Filter flags: -c/--chains TRB, -o (drop out-of-frame), -t (drop stops), --export-productive-clones-only.

For AIRR-schema interchange (Immcantation, scirpy, any AIRR tool) use the dedicated command, which emits sequence_id, v_call, d_call, j_call, junction, junction_aa, productive, duplicate_count, cell_id:

bash
mixcr exportAirr clones.clns clones.airr.tsv

Field-name traps (do NOT use as MiXCR selectors): count/frequency/cdr3_aa/vGene are VDJtools/AIRR conventions, not MiXCR headers. A downstream tool expecting AIRR names should be fed exportAirr output, not renamed native output.

The D-gene caveat: never key or trust the D call in TRB/IGH

Dbeta and Dh segments are short (~12-16 nt) and heavily trimmed at both ends with N-additions between; the surviving germline-matchable D stretch is often 0-5 nt, statistically indistinguishable from random junctional nucleotides. A substantial fraction of TRB rearrangements have no detectable D at all (de Greef & de Boer 2021 PNAS 118:e2104367118), and any "longest germline D match" over-calls D by chance. Treat bestDGene/allDHitsWithScore as unreliable: never use the D call as a clonotype key, never stratify biology by D usage without heavy skepticism, and expect large tool-to-tool D disagreement. Clonotypes are keyed on CDR3 + V + J -- not D. This caveat is TRB- and IGH-specific: the TRD (delta) chain can incorporate one to two D segments in tandem, giving more germline D content than TRB's single heavily-trimmed D, so the D call is more informative for gamma-delta work (the junction is still highly diverse from N-additions).

QC: match preset to chemistry, catch cross-contamination

bash
mixcr qc clones.clns
mixcr exportQc align results/*.clns qc_align.pdf
mixcr exportQc chainUsage results/*.clns qc_chainUsage.pdf

Read exportQc align: targeted amplicon should align high (often >80-90%); a low rate signals wrong species/library/boundaries or untrimmed primers, and "absent CDR3" means reads too short or wrong boundaries. RNA-seq mining legitimately aligns a tiny fraction (only receptor-overlapping reads) -- judge it by absolute clonotype yield, not %. Read chainUsage: a TRB library showing appreciable IGH signals cross-contamination or index hopping on patterned flowcells. A huge reads-to-clonotypes drop (millions -> thousands, worse after UMI collapse) is normal; a tiny clone count with high alignment suggests over-aggressive filtering or a wrong assembling feature.

Common Errors

SymptomCauseFix
Every processing command (align/analyze/assemble) refuses to runNo activated license (4.x mandatory for the pipeline; mixcr --version/exportPreset still work)mixcr activate-license or set MI_LICENSE_FILE; whitelist phone-home IPs on firewalled nodes
mixcr analyze amplicon ... unknown3.x command removed in 4.xUse mixcr analyze <preset>; pick a chemistry-matched preset
Runs cleanly but clonotypes look wrong (truncated CDR3, odd V calls)Wrong preset / boundary / material -- silent, no errorMatch preset to chemistry; audit with mixcr exportPreset; check exportQc align
Diversity far too high, many near-identical clonesUMI kit run without tag pattern -> no barcode collapseUse the UMI preset or add --tag-pattern; ensure refineTagsAndSort ran; report uniqueMoleculeCount
RNA-seq run yields almost no clonotypesNo assemblePartial/extend; partials filtered at alignalign --keep-non-CDR3-alignments, assemblePartial twice, then extend (or use rna-seq preset)
assemble errors asking for an assembling featurePreset lacks intrinsic feature (4.7+)Add --assemble-clonotypes-by CDR3 (or VDJRegion)
Downstream AIRR tool rejects the tableFed native MiXCR headers, not AIRRExport with mixcr exportAirr, not renamed exportClones
D-gene usage plot looks meaningless / irreproducibleTrusting the near-unassignable D call in TRB/IGHDrop D from keys and usage; report V/J only
--species missing on a generic presetGeneric presets require speciesAdd --species hsa (or mmu, taxon id)
refineTagsAndSort out-of-memory on single-cellBarcode-heavy step needs large heapmixcr -Xmx32g refineTagsAndSort ...
  • vdjtools-analysis - Downstream diversity and overlap on bulk clonotypes
  • immcantation-analysis - BCR clonal clustering, SHM and lineage from AIRR output
  • scirpy-analysis - Single-cell VDJ integration with gene expression
  • repertoire-visualization - Plot V/J usage and clonal structure
  • specificity-annotation - Antigen-specificity clustering and database lookup
  • read-qc/adapter-trimming - Upstream read QC and adapter handling
  • workflows/tcr-pipeline - End-to-end orchestration

References

  • Bolotin DA, et al. MiXCR: software for comprehensive adaptive immunity profiling. Nat Methods 12:380-381 (2015).
  • Bolotin DA, et al. Antigen receptor repertoire profiling from RNA-seq data. Nat Biotechnol 35:908-911 (2017).
  • de Greef PC, de Boer RJ. TCRbeta rearrangements without a D segment are common, abundant, and public. PNAS 118:e2104367118 (2021).
  • Vander Heiden JA, et al. AIRR Community standardized representations for annotated immune repertoires. Front Immunol 9:2206 (2018).
  • MiXCR documentation. https://mixcr.com/mixcr/ (presets, mixins, exportClones/exportAirr, licensing, QC).

© GPTomics, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

SKILL.md and 2 other files in tcr-bcr-analysis/mixcr-analysis of GPTomics/bioSkills.

  • SKILL.md
  • examples/mixcr_workflow.sh
  • usage-guide.md

Open the folder on GitHubat commit d91ed3d

Used in 1 other repository

We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in GPTomics/bioSkills, which our catalogue first saw on October 7, 2026.

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Categories

Questions about Bio Tcr Bcr Analysis Mixcr Analysis

What does Bio Tcr Bcr Analysis Mixcr Analysis do?

Align V(D)J reads and assemble TCR/BCR clonotypes with MiXCR, driven by a chemistry-matched preset. Bio Tcr Bcr Analysis Mixcr Analysis is an agent skill from GPTomics/bioSkills. Align V(D)J reads and assemble TCR/BCR clonotypes with MiXCR, driven by a chemistry-matched preset.

When should I use Bio Tcr Bcr Analysis Mixcr Analysis?

Bio Tcr Bcr Analysis Mixcr Analysis fits situations like: choosing/auditing the preset for a library (5RACE/template-switch vs multiplex-primer amplicon - rigid vs floating boundaries; RNA vs gDNA - --rna/--dna; bulk vs 10x single-cell; UMI vs no-UMI - tag pattern and barcode collapse.

How do I install Bio Tcr Bcr Analysis Mixcr Analysis in Claude Code?

Run `npx skills add GPTomics/bioSkills --skill bio-tcr-bcr-analysis-mixcr-analysis -a claude-code`. Or copy the skill folder (tcr-bcr-analysis/mixcr-analysis in GPTomics/bioSkills) into .claude/skills/bio-tcr-bcr-analysis-mixcr-analysis in your project. Claude Code loads it when a task matches its description.

How do I install Bio Tcr Bcr Analysis Mixcr Analysis in Codex?

Run `npx skills add GPTomics/bioSkills --skill bio-tcr-bcr-analysis-mixcr-analysis -a codex`. Or copy the skill folder (tcr-bcr-analysis/mixcr-analysis in GPTomics/bioSkills) into .agents/skills/bio-tcr-bcr-analysis-mixcr-analysis in your project. Codex loads it when a task matches its description.

Can I use Bio Tcr Bcr Analysis Mixcr Analysis in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add GPTomics/bioSkills --skill bio-tcr-bcr-analysis-mixcr-analysis -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bio-tcr-bcr-analysis-mixcr-analysis, .gemini/skills/bio-tcr-bcr-analysis-mixcr-analysis, .github/skills/bio-tcr-bcr-analysis-mixcr-analysis and .opencode/skills/bio-tcr-bcr-analysis-mixcr-analysis in your project.

What does Bio Tcr Bcr Analysis Mixcr Analysis need to run?

Going by SKILL.md and its folder, Bio Tcr Bcr Analysis Mixcr Analysis needs a shell for the scripts in its folder. Our summary lists: A Bash shell; Docker.

Does Bio Tcr Bcr Analysis Mixcr Analysis access the network?

SKILL.md names 1 domain. As links in the text: mixcr.com. This is read from the text; nothing was executed.

Is Bio Tcr Bcr Analysis Mixcr Analysis safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Bio Tcr Bcr Analysis Mixcr Analysis use?

Bio Tcr Bcr Analysis Mixcr Analysis is published under the MIT licence (the repository's licence). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Bio Tcr Bcr Analysis Mixcr Analysis use?

About 4.1k tokens (SKILL.md is roughly 16k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Bio Tcr Bcr Analysis Mixcr Analysis?

Skills that share tags, products or a category with Bio Tcr Bcr Analysis Mixcr Analysis: Bulkrna Cosinor Rhythm (TianGzlab/OmicsClaw, 161 stars), Ukb Ppp Region Fetch (ClawBio/ClawBio, 1.2k stars), Spatial Xenium (QING1105/ezST, 101 stars) and Tooluniverse Rnaseq Deseq2 (wu-yc/LabClaw, 1.1k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Bio Tcr Bcr Analysis Mixcr Analysis?

GPTomics (a GitHub organization) maintains it in GPTomics/bioSkills, which has 1,218 GitHub stars. The repository holds 559 skills in this directory. The repository was last updated on August 15, 2026.

Source: GPTomics/bioSkills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.