Experimental Design
Oleafly/Oleafly
Design experiments and studies BEFORE data is collected — choosing a design, randomizing, blocking, and laying out treatment combinations so results are interpretable.
A skill your agent uses to confirm study-design rigor and the mandatory prospective trial registration, protocol, and statistical analysis plan before writing up a clinical study for NEJM.
Install Nejm Study Design
$ npx skills add franklee16/academic-research-skills --skill nejm-study-design -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install franklee16/academic-research-skills nejm-study-design --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/franklee16/academic-research-skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design .claude/skills/nejm-study-design && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "nejm-study-design" agent skill from https://github.com/franklee16/academic-research-skills/tree/master/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design into .claude/skills/nejm-study-design/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "nejm-study-design", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/franklee16/academic-research-skills/tree/master/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-designType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add franklee16/academic-research-skills --skill nejm-study-design -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install franklee16/academic-research-skills nejm-study-design --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/franklee16/academic-research-skills.git skills-src && mkdir -p .agents/skills && cp -r skills-src/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design .agents/skills/nejm-study-design && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "nejm-study-design" agent skill from https://github.com/franklee16/academic-research-skills/tree/master/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design into .agents/skills/nejm-study-design/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "nejm-study-design", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add franklee16/academic-research-skills --skill nejm-study-design -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install franklee16/academic-research-skills nejm-study-design --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/franklee16/academic-research-skills.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design .cursor/skills/nejm-study-design && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "nejm-study-design" agent skill from https://github.com/franklee16/academic-research-skills/tree/master/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design into .cursor/skills/nejm-study-design/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "nejm-study-design", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/franklee16/academic-research-skills.git --path Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add franklee16/academic-research-skills --skill nejm-study-design -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install franklee16/academic-research-skills nejm-study-design --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/franklee16/academic-research-skills.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design .gemini/skills/nejm-study-design && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "nejm-study-design" agent skill from https://github.com/franklee16/academic-research-skills/tree/master/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design into .gemini/skills/nejm-study-design/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "nejm-study-design", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install franklee16/academic-research-skills nejm-study-designInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add franklee16/academic-research-skills --skill nejm-study-design -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/franklee16/academic-research-skills.git skills-src && mkdir -p .github/skills && cp -r skills-src/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design .github/skills/nejm-study-design && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "nejm-study-design" agent skill from https://github.com/franklee16/academic-research-skills/tree/master/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design into .github/skills/nejm-study-design/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "nejm-study-design", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add franklee16/academic-research-skills --skill nejm-study-design -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install franklee16/academic-research-skills nejm-study-design --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/franklee16/academic-research-skills.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design .opencode/skills/nejm-study-design && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "nejm-study-design" agent skill from https://github.com/franklee16/academic-research-skills/tree/master/Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design into .opencode/skills/nejm-study-design/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "nejm-study-design", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
Facts
- Skill name
nejm-study-design- GitHub stars
- 223
- Used in
- 1 other repo
- Token cost
- ~1.1k tokens
- SKILL.md length
- 438 words
- Files
- 1
- Skills in repo
- 1,617
- Repo updated
- First seen
- Licence
- None found
At a glance
A skill your agent uses to confirm study-design rigor and the mandatory prospective trial registration, protocol, and statistical analysis plan before writing up a clinical study for NEJM.
- Confirm study-design rigor and the mandatory prospective trial registration
- SKILL.md covers When to trigger, The non-negotiable:…, Protocol and statistical… and Design rigor checklist (trials), plus 3 more sections
- Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md
- Statistical analysis plan before writing up a clinical study for NEJM
What it does
Nejm Study Design is an agent skill from franklee16/academic-research-skills. Use to confirm study-design rigor and the mandatory prospective trial registration, protocol, and statistical analysis plan before writing up a clinical study for NEJM. Surfaces registration problems early — they cannot be fixed retroactively.
Its SKILL.md is about 1.1k tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.
It sits in Research & Science, covering Experimental design and Statistics. The repository describes itself as: Comprehensive collection of Claude Code skills for academic research in economics, finance, and social sciences.
When your agent uses it
- Confirm study-design rigor and the mandatory prospective trial registration
- Statistical analysis plan before writing up a clinical study for NEJM
Example prompts
- “/nejm-study-design”
What it can do on your machine
Read from SKILL.md and the folder at commit 9a4b2db. It shows what the files ask for, not the result of running them.
Tool permissions
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Runs code
No scripts in the folder and no shell commands in SKILL.md.
From the folder's file list and the shell code blocks in SKILL.md.
Network
No URLs in SKILL.md.
From URLs in SKILL.md, links to its own repository left out.
Credentials
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
Context cost
Nejm Study Design loads about 1.1k tokens when it runs. Until then it costs about 65 tokens; SKILL.md has 438 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
Safety
Auto-check passed
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.
SKILL.md
Without a licence we can't republish the file, so here is its outline and opening line. It has 438 words (~1,066 tokens).
“Per ICMJE policy (which NEJM enforces), a clinical trial must be prospectively registered in a public registry — ClinicalTrials.gov or a WHO ICTRP primary registry — before the first patient is enrolled. This is a deal-breaker, not a formatting detail.”
- name
- nejm-study-design
Files
Just SKILL.md in Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design of franklee16/academic-research-skills.
Open the folder on GitHubat commit 9a4b2db
Used in 1 other repository
We found 1 copy of this SKILL.md (exact, near-identical or edited) in other folders, from 1 other GitHub owner. This page covers the copy in franklee16/academic-research-skills, which our catalogue first saw on October 7, 2026.
Compare with similar skills
Nejm Study Design next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| Nejm Study Design this skillfranklee16/academic-research-skills | 223 | 1 repos | ~1.1k | Automated safety check: Pass | None | |
| Experimental DesignOleafly/Oleafly | 212 | 3 repos | ~3.5k | Automated safety check: Notes | MIT | |
| Data Scientistmagnus919/hermes-profiles | 289 | — | ~3.3k | Automated safety check: Pass | MIT | |
| Data Scientistmagnus919/agent-skills | 115 | — | ~4.1k | Automated safety check: Pass | MIT | |
| Statistical PowerK-Dense-AI/scientific-agent-skills | 48k | 1 repos | ~4.4k | Automated safety check: Notes | MIT | |
| Algo Rank Wilsonasgard-ai-platform/skills | 242 | — | ~1.1k | Automated safety check: Pass | MIT |
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Related
Categories
Questions about Nejm Study Design
What does Nejm Study Design do?
A skill your agent uses to confirm study-design rigor and the mandatory prospective trial registration, protocol, and statistical analysis plan before writing up a clinical study for NEJM. Nejm Study Design is an agent skill from franklee16/academic-research-skills. Use to confirm study-design rigor and the mandatory prospective trial registration, protocol, and statistical analysis plan before writing up a clinical study for NEJM.
When should I use Nejm Study Design?
Nejm Study Design fits situations like: confirm study-design rigor and the mandatory prospective trial registration; statistical analysis plan before writing up a clinical study for NEJM.
How do I install Nejm Study Design in Claude Code?
Run `npx skills add franklee16/academic-research-skills --skill nejm-study-design -a claude-code`. Or copy the skill folder (Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design in franklee16/academic-research-skills) into .claude/skills/nejm-study-design in your project. Claude Code loads it when a task matches its description.
How do I install Nejm Study Design in Codex?
Run `npx skills add franklee16/academic-research-skills --skill nejm-study-design -a codex`. Or copy the skill folder (Awesome-Journal-Skills-main/NEJM-Skills/skills/nejm-study-design in franklee16/academic-research-skills) into .agents/skills/nejm-study-design in your project. Codex loads it when a task matches its description.
Can I use Nejm Study Design in Cursor, Gemini CLI or GitHub Copilot?
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add franklee16/academic-research-skills --skill nejm-study-design -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/nejm-study-design, .gemini/skills/nejm-study-design, .github/skills/nejm-study-design and .opencode/skills/nejm-study-design in your project.
What does Nejm Study Design need to run?
SKILL.md names no scripts, command-line tools or credentials: Nejm Study Design is instructions for the agent only.
Does Nejm Study Design access the network?
SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.
Is Nejm Study Design safe to install?
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.
What licence does Nejm Study Design use?
No licence was found for Nejm Study Design or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.
How many tokens does Nejm Study Design use?
About 1.1k tokens (SKILL.md is roughly 4.3k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.
What are the alternatives to Nejm Study Design?
Skills that share tags, products or a category with Nejm Study Design: Experimental Design (Oleafly/Oleafly, 212 stars), Data Scientist (magnus919/hermes-profiles, 289 stars), Data Scientist (magnus919/agent-skills, 115 stars) and Statistical Power (K-Dense-AI/scientific-agent-skills, 48k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
Who maintains Nejm Study Design?
franklee16 (a GitHub user) maintains it in franklee16/academic-research-skills, which has 223 GitHub stars. The repository holds 1,617 skills in this directory. The repository was last updated on September 18, 2026.
Source: franklee16/academic-research-skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.