Agent skill

Bioconductor Msa2dist

by bioMate-AI in bioMate-AI/biomate-bioconductor-kb

MSA2dist calculates pairwise distances between all sequences of a DNAStringSet or a AAStringSet using a custom score matrix and conducts codon based analysis.

Custom licenceAuto-check passedResearch & Science

Install Bioconductor Msa2dist

skills CLI
$ npx skills add bioMate-AI/biomate-bioconductor-kb --skill bioconductor-msa2dist -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install bioMate-AI/biomate-bioconductor-kb bioconductor-msa2dist --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/bioMate-AI/biomate-bioconductor-kb.git skills-src && mkdir -p .claude/skills && cp -r skills-src/skills/genomics/msa2dist .claude/skills/bioconductor-msa2dist && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
bioconductor-msa2dist
GitHub stars
804
Token cost
~1.3k tokens
SKILL.md length
497 words
Files
1
Skills in repo
112
Repo updated
First seen
Licence
Custom licence

At a glance

MSA2dist calculates pairwise distances between all sequences of a DNAStringSet or a AAStringSet using a custom score matrix and conducts codon based analysis.

  • Research & Science work in your project
  • SKILL.md covers Workflows, When to Use, When NOT to Use and Data Requirements, plus 6 more sections
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Bioconductor Msa2dist is an agent skill from bioMate-AI/biomate-bioconductor-kb. MSA2dist calculates pairwise distances between all sequences of a DNAStringSet or a AAStringSet using a custom score matrix and conducts codon based analysis. It uses scoring matrices to be used in these pairwise distance calcualtions which can be adapted to any scoring for DNA or AA characters. E.g. by using literal distances MSA2dist calculates pairwise IUPAC distances.

Its SKILL.md is about 1.3k tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.

It sits in Research & Science. The repository describes itself as: BioMate-KB Bioconductor Skills — 200 packages (top 100 by downloads + 100 rising stars) as vignette-grounded Claude/agent skills, with per-package workflow recipes.

When your agent uses it

  • Research & Science work in your project

Example prompts

  • “/bioconductor-msa2dist”

What it can do on your machine

Read from SKILL.md and the folder at commit c9bd4d8. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md (its code samples are r).

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    Links to these hosts (documentation or services it may open):

    • bioconductor.org

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Bioconductor Msa2dist loads about 1.3k tokens when it runs. Until then it costs about 99 tokens; SKILL.md has 497 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~99
When it runs · the whole SKILL.md, loaded when a task matches
~1.3k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Its licence (Custom licence) doesn't allow us to republish the file, so here is its outline and opening line. It has 497 words (~1,293 tokens).

“MSA2dist calculates pairwise distances between all sequences of a DNAStringSet or a AAStringSet using a custom score matrix and conducts codon based analysis. It uses scoring matrices to be used in these pairwise distance calculations which can be adapted to…”

— opening of SKILL.md by bioMate-AI, Custom licence
name
bioconductor-msa2dist
when_to_use
Use when: MSA2dist calculates pairwise distances between all sequences of a DNAStringSet or a AAStringSet using a custom score mat; MSA2dist Vignette. Not…
user-invocable
false

Read the full SKILL.md on GitHub

Files

Just SKILL.md in skills/genomics/msa2dist of bioMate-AI/biomate-bioconductor-kb.

Open the folder on GitHubat commit c9bd4d8

Compare with similar skills

Bioconductor Msa2dist next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Bioconductor Msa2dist compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Bioconductor Msa2dist this skillbioMate-AI/biomate-bioconductor-kb804—~1.3kAutomated safety check: PassCustom licence
Hypothesis Generationspacering-net/codeg3.9k14 repos~3.6kAutomated safety check: NotesMIT
GitHub Deep Researchbytedance/deer-flow84k4 repos~1.3kAutomated safety check: PassMIT
Nature Paper CardYuan1z0825/nature-skills47k2 repos~2.1kAutomated safety check: PassApache-2.0
Content Research Writerweapp-tailwindcss/weapp-tailwindcss1.9k25 repos~3.5kAutomated safety check: PassMIT
Last30daysmvanhorn/last30days-skill64k—~7.9kAutomated safety check: NotesMIT

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Questions about Bioconductor Msa2dist

What does Bioconductor Msa2dist do?

MSA2dist calculates pairwise distances between all sequences of a DNAStringSet or a AAStringSet using a custom score matrix and conducts codon based analysis. Bioconductor Msa2dist is an agent skill from bioMate-AI/biomate-bioconductor-kb. MSA2dist calculates pairwise distances between all sequences of a DNAStringSet or a AAStringSet using a custom score matrix and conducts codon based analysis.

When should I use Bioconductor Msa2dist?

Bioconductor Msa2dist fits situations like: research & Science work in your project.

How do I install Bioconductor Msa2dist in Claude Code?

Run `npx skills add bioMate-AI/biomate-bioconductor-kb --skill bioconductor-msa2dist -a claude-code`. Or copy the skill folder (skills/genomics/msa2dist in bioMate-AI/biomate-bioconductor-kb) into .claude/skills/bioconductor-msa2dist in your project. Claude Code loads it when a task matches its description.

How do I install Bioconductor Msa2dist in Codex?

Run `npx skills add bioMate-AI/biomate-bioconductor-kb --skill bioconductor-msa2dist -a codex`. Or copy the skill folder (skills/genomics/msa2dist in bioMate-AI/biomate-bioconductor-kb) into .agents/skills/bioconductor-msa2dist in your project. Codex loads it when a task matches its description.

Can I use Bioconductor Msa2dist in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add bioMate-AI/biomate-bioconductor-kb --skill bioconductor-msa2dist -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/bioconductor-msa2dist, .gemini/skills/bioconductor-msa2dist, .github/skills/bioconductor-msa2dist and .opencode/skills/bioconductor-msa2dist in your project.

What does Bioconductor Msa2dist need to run?

SKILL.md names no scripts, command-line tools or credentials: Bioconductor Msa2dist is instructions for the agent only.

Does Bioconductor Msa2dist access the network?

SKILL.md names 1 domain. As links in the text: bioconductor.org. This is read from the text; nothing was executed.

Is Bioconductor Msa2dist safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Bioconductor Msa2dist use?

Bioconductor Msa2dist has a licence file (the repository's licence) that doesn't match a standard licence. Read it on GitHub before reusing the skill.

How many tokens does Bioconductor Msa2dist use?

About 1.3k tokens (SKILL.md is roughly 5.2k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Bioconductor Msa2dist?

Skills that share tags, products or a category with Bioconductor Msa2dist: Hypothesis Generation (spacering-net/codeg, 3.9k stars), GitHub Deep Research (bytedance/deer-flow, 84k stars), Nature Paper Card (Yuan1z0825/nature-skills, 47k stars) and Content Research Writer (weapp-tailwindcss/weapp-tailwindcss, 1.9k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Bioconductor Msa2dist?

bioMate-AI (a GitHub organization) maintains it in bioMate-AI/biomate-bioconductor-kb, which has 804 GitHub stars. The repository holds 112 skills in this directory. The repository was last updated on June 20, 2026.

Source: bioMate-AI/biomate-bioconductor-kb on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.