Official agent skill

Instrument Data To Allotrope

by aws-samples in aws-samples/amazon-bedrock-agents-healthcare-lifesciences

Convert laboratory instrument output files (PDF, CSV, Excel, TXT) to Allotrope Simple Model (ASM) JSON format or flattened 2D CSV.

OfficialApache-2.0Auto-check passedDocuments & Office

Install Instrument Data To Allotrope

skills CLI
$ npx skills add aws-samples/amazon-bedrock-agents-healthcare-lifesciences --skill instrument-data-to-allotrope -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install aws-samples/amazon-bedrock-agents-healthcare-lifesciences instrument-data-to-allotrope --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/aws-samples/amazon-bedrock-agents-healthcare-lifesciences.git skills-src && mkdir -p .claude/skills && cp -r skills-src/agents_catalog/36-C4LS-example-agent/C4LS/src/skills/instrument-data-to-allotrope .claude/skills/instrument-data-to-allotrope && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
instrument-data-to-allotrope
GitHub stars
274
Used in
2 other repos
Token cost
~2.7k tokens
SKILL.md length
818 words
Files
11 (incl. scripts, references)
Skills in repo
12
Repo updated
First seen
Licence
Apache-2.0

At a glance

Convert laboratory instrument output files (PDF, CSV, Excel, TXT) to Allotrope Simple Model (ASM) JSON format or flattened 2D CSV.

  • Works in 4 steps: Detect instrument type from file… → Parse file using allotropy library… → Generate outputs → …
  • Scientists need to standardize instrument data for LIMS systems
  • SKILL.md covers Workflow Overview, Quick Start, Output Format Selection and Calculated Data Handling, plus 9 more sections
  • Runs Python scripts from its folder; calls python and pip

What it does

Instrument Data To Allotrope is an agent skill from aws-samples/amazon-bedrock-agents-healthcare-lifesciences, published by the product's own GitHub organization. Convert laboratory instrument output files (PDF, CSV, Excel, TXT) to Allotrope Simple Model (ASM) JSON format or flattened 2D CSV. Use this skill when scientists need to standardize instrument data for LIMS systems, data lakes, or downstream analysis. Supports auto-detection of instrument types. Outputs include full ASM JSON, flattened CSV for easy import, and exportable Python code for data engineers. Common triggers include converting instrument files, standardizing lab data, preparing data for upload to…

Its SKILL.md is about 2.7k tokens, which your agent loads only when the skill is triggered. The skill folder holds 12 other files, including scripts and reference files (for example `references/asm_schema_overview.md`, `references/field_classification_guide.md` and `references/flattening_guide.md`).

It sits in Documents & Office, covering CSV and tabular files, Excel spreadsheets and PDF. It works with Python and Microsoft Excel. The licence is Apache-2.0.

When your agent uses it

  • Scientists need to standardize instrument data for LIMS systems
  • Downstream analysis
  • Include converting instrument files
  • Standardizing lab data

Example prompts

  • “/instrument-data-to-allotrope”

Requirements

  • Python 3

Workflow steps

4 steps, taken from the first numbered list in SKILL.md.

  1. Detect instrument type from file contents (auto-detect or user-specified)
  2. Parse file using allotropy library (native) or flexible fallback parser
  3. Generate outputs
  4. Deliver files with summary and usage instructions

What it can do on your machine

Read from SKILL.md and the folder at commit 9960565. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    Ships 4 files in scripts/ (Python), which the agent can run.

    Shell commands in SKILL.md call:

    • python
    • pip

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    Links to these hosts (documentation or services it may open):

    • gitlab.com

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Instrument Data To Allotrope loads about 2.7k tokens when it runs, and up to ~12k if it reads all its reference files. Until then it costs about 153 tokens; SKILL.md has 818 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~153
When it runs · the whole SKILL.md, loaded when a task matches
~2.7k
With references · SKILL.md plus every file in references/, read only if the agent opens them
~12k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); the scripts in this folder are not scanned.

SKILL.md

The full file from aws-samples/amazon-bedrock-agents-healthcare-lifesciences at commit 9960565, republished under its Apache-2.0 licence (© aws-samples). 818 words, ~2,661 tokens.

Download SKILL.mdSave it as .claude/skills/instrument-data-to-allotrope/SKILL.md (or your agent's skills folder). This skill also uses 10 other files; get the full folder from GitHub.
name
instrument-data-to-allotrope
description
Convert laboratory instrument output files (PDF, CSV, Excel, TXT) to Allotrope Simple Model (ASM) JSON format or flattened 2D CSV. Use this skill when scientists need to standardize instrument data for LIMS systems, data lakes, or downstream analysis. Supports auto-detection of instrument types. Outputs include full ASM JSON, flattened CSV for easy import, and exportable Python code for data engineers. Common triggers include converting instrument files, standardizing lab data, preparing data for upload to LIMS/ELN systems, or generating parser code for production pipelines.

Instrument Data to Allotrope Converter

Convert instrument files into standardized Allotrope Simple Model (ASM) format for LIMS upload, data lakes, or handoff to data engineering teams.

Note: This is an Example Skill

This skill demonstrates how skills can support your data engineering tasks—automating schema transformations, parsing instrument outputs, and generating production-ready code.

To customize for your organization:

  • Modify the references/ files to include your company's specific schemas or ontology mappings
  • Use an MCP server to connect to systems that define your schemas (e.g., your LIMS, data catalog, or schema registry)
  • Extend the scripts/ to handle proprietary instrument formats or internal data standards

This pattern can be adapted for any data transformation workflow where you need to convert between formats or validate against organizational standards.

Workflow Overview

  1. Detect instrument type from file contents (auto-detect or user-specified)
  2. Parse file using allotropy library (native) or flexible fallback parser
  3. Generate outputs:
    • ASM JSON (full semantic structure)
    • Flattened CSV (2D tabular format)
    • Python parser code (for data engineer handoff)
  4. Deliver files with summary and usage instructions

When Uncertain: If you're unsure how to map a field to ASM (e.g., is this raw data or calculated? device setting or environmental condition?), ask the user for clarification. Refer to references/field_classification_guide.md for guidance, but when ambiguity remains, confirm with the user rather than guessing.

Quick Start

python
# Install requirements first
pip install allotropy pandas openpyxl pdfplumber --break-system-packages

# Core conversion
from allotropy.parser_factory import Vendor
from allotropy.to_allotrope import allotrope_from_file

# Convert with allotropy
asm = allotrope_from_file("instrument_data.csv", Vendor.BECKMAN_VI_CELL_BLU)

Output Format Selection

ASM JSON (default) - Full semantic structure with ontology URIs

  • Best for: LIMS systems expecting ASM, data lakes, long-term archival
  • Validates against Allotrope schemas

Flattened CSV - 2D tabular representation

  • Best for: Quick analysis, Excel users, systems without JSON support
  • Each measurement becomes one row with metadata repeated

Both - Generate both formats for maximum flexibility

Calculated Data Handling

IMPORTANT: Separate raw measurements from calculated/derived values.

  • Raw data → measurement-document (direct instrument readings)
  • Calculated data → calculated-data-aggregate-document (derived values)

Calculated values MUST include traceability via data-source-aggregate-document:

json
"calculated-data-aggregate-document": {
  "calculated-data-document": [{
    "calculated-data-identifier": "SAMPLE_B1_DIN_001",
    "calculated-data-name": "DNA integrity number",
    "calculated-result": {"value": 9.5, "unit": "(unitless)"},
    "data-source-aggregate-document": {
      "data-source-document": [{
        "data-source-identifier": "SAMPLE_B1_MEASUREMENT",
        "data-source-feature": "electrophoresis trace"
      }]
    }
  }]
}

Common calculated fields by instrument type:

InstrumentCalculated Fields
Cell counterViability %, cell density dilution-adjusted values
SpectrophotometerConcentration (from absorbance), 260/280 ratio
Plate readerConcentrations from standard curve, %CV
ElectrophoresisDIN/RIN, region concentrations, average sizes
qPCRRelative quantities, fold change

See references/field_classification_guide.md for detailed guidance on raw vs. calculated classification.

Validation

Always validate ASM output before delivering to the user:

bash
python scripts/validate_asm.py output.json
python scripts/validate_asm.py output.json --reference known_good.json  # Compare to reference
python scripts/validate_asm.py output.json --strict  # Treat warnings as errors

Validation Rules:

Soft Validation Approach: Unknown techniques, units, or sample roles generate warnings (not errors) to allow for forward compatibility. If Allotrope adds new values after December 2024, the validator won't block them—it will flag them for manual verification. Use --strict mode to treat warnings as errors if you need stricter validation.

What it checks:

  • Correct technique selection (e.g., multi-analyte profiling vs plate reader)
  • Field naming conventions (space-separated, not hyphenated)
  • Calculated data has traceability (data-source-aggregate-document)
  • Unique identifiers exist for measurements and calculated values
  • Required metadata present
  • Valid units and sample roles (with soft validation for unknown values)
Show full SKILL.md (343 more words)Show less

Supported Instruments

See references/supported_instruments.md for complete list. Key instruments:

CategoryInstruments
Cell CountingVi-CELL BLU, Vi-CELL XR, NucleoCounter
SpectrophotometryNanoDrop One/Eight/8000, Lunatic
Plate ReadersSoftMax Pro, EnVision, Gen5, CLARIOstar
ELISASoftMax Pro, BMG MARS, MSD Workbench
qPCRQuantStudio, Bio-Rad CFX
ChromatographyEmpower, Chromeleon

Detection & Parsing Strategy

Tier 1: Native allotropy parsing (PREFERRED)

Always try allotropy first. Check available vendors directly:

python
from allotropy.parser_factory import Vendor

# List all supported vendors
for v in Vendor:
    print(f"{v.name}")

# Common vendors:
# AGILENT_TAPESTATION_ANALYSIS  (for TapeStation XML)
# BECKMAN_VI_CELL_BLU
# THERMO_FISHER_NANODROP_EIGHT
# MOLDEV_SOFTMAX_PRO
# APPBIO_QUANTSTUDIO
# ... many more

When the user provides a file, check if allotropy supports it before falling back to manual parsing. The scripts/convert_to_asm.py auto-detection only covers a subset of allotropy vendors.

Tier 2: Flexible fallback parsing

Only use if allotropy doesn't support the instrument. This fallback:

  • Does NOT generate calculated-data-aggregate-document
  • Does NOT include full traceability
  • Produces simplified ASM structure

Use flexible parser with:

  • Column name fuzzy matching
  • Unit extraction from headers
  • Metadata extraction from file structure
Tier 3: PDF extraction

For PDF-only files, extract tables using pdfplumber, then apply Tier 2 parsing.

Pre-Parsing Checklist

Before writing a custom parser, ALWAYS:

  1. Check if allotropy supports it - Use native parser if available
  2. Find a reference ASM file - Check references/examples/ or ask user
  3. Review instrument-specific guide - Check references/instrument_guides/
  4. Validate against reference - Run validate_asm.py --reference <file>

Common Mistakes to Avoid

MistakeCorrect Approach
Manifest as objectUse URL string
Lowercase detection typesUse "Absorbance" not "absorbance"
"emission wavelength setting"Use "detector wavelength setting" for emission
All measurements in one documentGroup by well/sample location
Missing procedure metadataExtract ALL device settings per measurement

Code Export for Data Engineers

Generate standalone Python scripts that scientists can hand off:

python
# Export parser code
python scripts/export_parser.py --input "data.csv" --vendor "VI_CELL_BLU" --output "parser_script.py"

The exported script:

  • Has no external dependencies beyond pandas/allotropy
  • Includes inline documentation
  • Can run in Jupyter notebooks
  • Is production-ready for data pipelines

File Structure

instrument-data-to-allotrope/
├── SKILL.md                          # This file
├── scripts/
│   ├── convert_to_asm.py            # Main conversion script
│   ├── flatten_asm.py               # ASM → 2D CSV conversion
│   ├── export_parser.py             # Generate standalone parser code
│   └── validate_asm.py              # Validate ASM output quality
└── references/
    ├── supported_instruments.md     # Full instrument list with Vendor enums
    ├── asm_schema_overview.md       # ASM structure reference
    ├── field_classification_guide.md # Where to put different field types
    └── flattening_guide.md          # How flattening works

Usage Examples

Example 1: Vi-CELL BLU file
User: "Convert this cell counting data to Allotrope format"
[uploads viCell_Results.xlsx]

Claude:
1. Detects Vi-CELL BLU (95% confidence)
2. Converts using allotropy native parser
3. Outputs:
   - viCell_Results_asm.json (full ASM)
   - viCell_Results_flat.csv (2D format)
   - viCell_parser.py (exportable code)
Example 2: Request for code handoff
User: "I need to give our data engineer code to parse NanoDrop files"

Claude:
1. Generates self-contained Python script
2. Includes sample input/output
3. Documents all assumptions
4. Provides Jupyter notebook version
Example 3: LIMS-ready flattened output
User: "Convert this ELISA data to a CSV I can upload to our LIMS"

Claude:
1. Parses plate reader data
2. Generates flattened CSV with columns:
   - sample_identifier, well_position, measurement_value, measurement_unit
   - instrument_serial_number, analysis_datetime, assay_type
3. Validates against common LIMS import requirements

Implementation Notes

Installing allotropy
bash
pip install allotropy --break-system-packages
Handling parse failures

If allotropy native parsing fails:

  1. Log the error for debugging
  2. Fall back to flexible parser
  3. Report reduced metadata completeness to user
  4. Suggest exporting different format from instrument
ASM Schema Validation

Validate output against Allotrope schemas when available:

python
import jsonschema
# Schema URLs in references/asm_schema_overview.md

© aws-samples, Apache-2.0. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

SKILL.md and 10 other files (scripts, references) in agents_catalog/36-C4LS-example-agent/C4LS/src/skills/instrument-data-to-allotrope of aws-samples/amazon-bedrock-agents-healthcare-lifesciences.

  • SKILL.md
  • LICENSE.txt
  • references/asm_schema_overview.md
  • references/field_classification_guide.md
  • references/flattening_guide.md
  • references/supported_instruments.md
  • requirements.txt
  • scripts/convert_to_asm.py
  • scripts/export_parser.py
  • scripts/flatten_asm.py
  • scripts/validate_asm.py

Open the folder on GitHubat commit 9960565

Used in 2 other repositories

We found 2 copies of this SKILL.md (exact, near-identical or edited) in other folders, from 2 other GitHub owners. This page covers the copy in aws-samples/amazon-bedrock-agents-healthcare-lifesciences, which our catalogue first saw on October 7, 2026.

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Questions about Instrument Data To Allotrope

What does Instrument Data To Allotrope do?

Convert laboratory instrument output files (PDF, CSV, Excel, TXT) to Allotrope Simple Model (ASM) JSON format or flattened 2D CSV. Instrument Data To Allotrope is an agent skill from aws-samples/amazon-bedrock-agents-healthcare-lifesciences, published by the product's own GitHub organization. Convert laboratory instrument output files (PDF, CSV, Excel, TXT) to Allotrope Simple Model (ASM) JSON format or flattened 2D CSV.

When should I use Instrument Data To Allotrope?

Instrument Data To Allotrope fits situations like: scientists need to standardize instrument data for LIMS systems; downstream analysis; include converting instrument files; standardizing lab data.

How do I install Instrument Data To Allotrope in Claude Code?

Run `npx skills add aws-samples/amazon-bedrock-agents-healthcare-lifesciences --skill instrument-data-to-allotrope -a claude-code`. Or copy the skill folder (agents_catalog/36-C4LS-example-agent/C4LS/src/skills/instrument-data-to-allotrope in aws-samples/amazon-bedrock-agents-healthcare-lifesciences) into .claude/skills/instrument-data-to-allotrope in your project. Claude Code loads it when a task matches its description.

How do I install Instrument Data To Allotrope in Codex?

Run `npx skills add aws-samples/amazon-bedrock-agents-healthcare-lifesciences --skill instrument-data-to-allotrope -a codex`. Or copy the skill folder (agents_catalog/36-C4LS-example-agent/C4LS/src/skills/instrument-data-to-allotrope in aws-samples/amazon-bedrock-agents-healthcare-lifesciences) into .agents/skills/instrument-data-to-allotrope in your project. Codex loads it when a task matches its description.

Can I use Instrument Data To Allotrope in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add aws-samples/amazon-bedrock-agents-healthcare-lifesciences --skill instrument-data-to-allotrope -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/instrument-data-to-allotrope, .gemini/skills/instrument-data-to-allotrope, .github/skills/instrument-data-to-allotrope and .opencode/skills/instrument-data-to-allotrope in your project.

What does Instrument Data To Allotrope need to run?

Going by SKILL.md and its folder, Instrument Data To Allotrope needs Python for the scripts in its folder and the command-line tools its instructions call (python and pip). Our summary lists: Python 3.

Does Instrument Data To Allotrope access the network?

SKILL.md names 1 domain. As links in the text: gitlab.com. This is read from the text; nothing was executed.

Is Instrument Data To Allotrope safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. The check reads SKILL.md only: the scripts in the folder are not scanned, so read them before running anything.

What licence does Instrument Data To Allotrope use?

Instrument Data To Allotrope is published under the Apache-2.0 licence (from the LICENSE file in the skill folder). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Instrument Data To Allotrope use?

About 2.7k tokens (SKILL.md is roughly 11k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 9.1k tokens, read only when the agent opens those files.

What are the alternatives to Instrument Data To Allotrope?

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Who maintains Instrument Data To Allotrope?

aws-samples (a GitHub organization, an official publisher) maintains it in aws-samples/amazon-bedrock-agents-healthcare-lifesciences, which has 274 GitHub stars. The repository holds 12 skills in this directory. The repository was last updated on October 1, 2026.

Source: aws-samples/amazon-bedrock-agents-healthcare-lifesciences on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.