Alphagenome Single Variant Analysis
google-deepmind/science-skills
Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API.
Анализирует генетические данные пользователя из VCF файла. An agent skill from artwist-polyakov/polyakov-claude-skills.
Install Genome Analyzer
$ npx skills add artwist-polyakov/polyakov-claude-skills --skill genome-analyzer -a claude-codeProject install by default; add -g for ~/.claude/skills/.
$ gh skill install artwist-polyakov/polyakov-claude-skills genome-analyzer --agent claude-codeProject scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).
$ git clone --depth 1 https://github.com/artwist-polyakov/polyakov-claude-skills.git skills-src && mkdir -p .claude/skills && cp -r skills-src/plugins/genome-analizer/skills/genome-analizer .claude/skills/genome-analyzer && rm -rf skills-srcUse ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.
Claude Code skills documentation · loads skills from .claude/skills/
Install the "genome-analyzer" agent skill from https://github.com/artwist-polyakov/polyakov-claude-skills/tree/main/plugins/genome-analizer/skills/genome-analizer into .claude/skills/genome-analyzer/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-analyzer", then confirm the skill loads.Claude Code copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$skill-installer install https://github.com/artwist-polyakov/polyakov-claude-skills/tree/main/plugins/genome-analizer/skills/genome-analizerType this inside Codex. $skill-installer <name> installs a curated skill from openai/skills. The installer writes to $CODEX_HOME/skills (default ~/.codex/skills). Restart Codex if the skill does not show up.
$ npx skills add artwist-polyakov/polyakov-claude-skills --skill genome-analyzer -a codexProject install goes to .agents/skills/; add -g for ~/.codex/skills/.
$ gh skill install artwist-polyakov/polyakov-claude-skills genome-analyzer --agent codexProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/artwist-polyakov/polyakov-claude-skills.git skills-src && mkdir -p .agents/skills && cp -r skills-src/plugins/genome-analizer/skills/genome-analizer .agents/skills/genome-analyzer && rm -rf skills-srcUse ~/.agents/skills/ instead of .agents/skills for a personal install.
Codex skills documentation · loads skills from .agents/skills/
Install the "genome-analyzer" agent skill from https://github.com/artwist-polyakov/polyakov-claude-skills/tree/main/plugins/genome-analizer/skills/genome-analizer into .agents/skills/genome-analyzer/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-analyzer", then confirm the skill loads.Codex copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add artwist-polyakov/polyakov-claude-skills --skill genome-analyzer -a cursorProject install goes to .agents/skills/; add -g for ~/.cursor/skills/.
$ gh skill install artwist-polyakov/polyakov-claude-skills genome-analyzer --agent cursorProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/artwist-polyakov/polyakov-claude-skills.git skills-src && mkdir -p .cursor/skills && cp -r skills-src/plugins/genome-analizer/skills/genome-analizer .cursor/skills/genome-analyzer && rm -rf skills-srcUse ~/.cursor/skills/ instead of .cursor/skills for a personal install.
Cursor skills documentation · loads skills from .cursor/skills/, .agents/skills/, .claude/skills/, .codex/skills/
Install the "genome-analyzer" agent skill from https://github.com/artwist-polyakov/polyakov-claude-skills/tree/main/plugins/genome-analizer/skills/genome-analizer into .cursor/skills/genome-analyzer/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-analyzer", then confirm the skill loads.Cursor copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gemini skills install https://github.com/artwist-polyakov/polyakov-claude-skills.git --path plugins/genome-analizer/skills/genome-analizer--scope user (default) or --scope workspace; --path is the subfolder of the repo that holds the skill; --consent skips the security confirmation prompt.
$ npx skills add artwist-polyakov/polyakov-claude-skills --skill genome-analyzer -a gemini-cliProject install goes to .agents/skills/; add -g for ~/.gemini/skills/.
$ gh skill install artwist-polyakov/polyakov-claude-skills genome-analyzer --agent gemini-cliProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/artwist-polyakov/polyakov-claude-skills.git skills-src && mkdir -p .gemini/skills && cp -r skills-src/plugins/genome-analizer/skills/genome-analizer .gemini/skills/genome-analyzer && rm -rf skills-srcUse ~/.gemini/skills/ instead of .gemini/skills for a personal install, then run /skills reload.
Gemini CLI skills documentation · loads skills from .gemini/skills/, .agents/skills/
Install the "genome-analyzer" agent skill from https://github.com/artwist-polyakov/polyakov-claude-skills/tree/main/plugins/genome-analizer/skills/genome-analizer into .gemini/skills/genome-analyzer/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-analyzer", then confirm the skill loads.Gemini CLI copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ gh skill install artwist-polyakov/polyakov-claude-skills genome-analyzerInstalls for Copilot at project scope by default; add --scope user for a personal install. Preview a skill first with gh skill preview. Needs GitHub CLI 2.90.0 or later (public preview).
$ npx skills add artwist-polyakov/polyakov-claude-skills --skill genome-analyzer -a github-copilotProject install goes to .agents/skills/; add -g for ~/.copilot/skills/.
$ git clone --depth 1 https://github.com/artwist-polyakov/polyakov-claude-skills.git skills-src && mkdir -p .github/skills && cp -r skills-src/plugins/genome-analizer/skills/genome-analizer .github/skills/genome-analyzer && rm -rf skills-srcUse ~/.copilot/skills/ instead of .github/skills for a personal install. Commit .github/skills so cloud agent and code review can use it.
GitHub Copilot skills documentation · loads skills from .github/skills/, .claude/skills/, .agents/skills/
Install the "genome-analyzer" agent skill from https://github.com/artwist-polyakov/polyakov-claude-skills/tree/main/plugins/genome-analizer/skills/genome-analizer into .github/skills/genome-analyzer/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-analyzer", then confirm the skill loads.GitHub Copilot copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
$ npx skills add artwist-polyakov/polyakov-claude-skills --skill genome-analyzer -a opencodeOpenCode documents no install command of its own. Project install goes to .agents/skills/; add -g for ~/.config/opencode/skills/.
$ gh skill install artwist-polyakov/polyakov-claude-skills genome-analyzer --agent opencodeProject scope by default (.agents/skills/); add --scope user for a personal install.
$ git clone --depth 1 https://github.com/artwist-polyakov/polyakov-claude-skills.git skills-src && mkdir -p .opencode/skills && cp -r skills-src/plugins/genome-analizer/skills/genome-analizer .opencode/skills/genome-analyzer && rm -rf skills-srcUse ~/.config/opencode/skills/ instead of .opencode/skills for a personal install.
OpenCode skills documentation · loads skills from .opencode/skills/, .claude/skills/, .agents/skills/
Install the "genome-analyzer" agent skill from https://github.com/artwist-polyakov/polyakov-claude-skills/tree/main/plugins/genome-analizer/skills/genome-analizer into .opencode/skills/genome-analyzer/ in this project. Copy the whole folder (SKILL.md and every file beside it), keep the folder name "genome-analyzer", then confirm the skill loads.OpenCode copies the folder itself, the same result as the manual copy. Check what it changed before you commit it.
Facts
- Skill name
genome-analyzer- GitHub stars
- 208
- Token cost
- ~966 tokens
- SKILL.md length
- 265 words
- Files
- 1
- Skills in repo
- 21
- Repo updated
- First seen
- Licence
- MIT
At a glance
Анализирует генетические данные пользователя из VCF файла. An agent skill from artwist-polyakov/polyakov-claude-skills.
- Tasks that involve Bioinformatics
- SKILL.md covers VCF файл, Алгоритм работы, Формат ответа and Эмодзи для оформления, plus 1 more section
- Reaches snpedia.com and ebi.ac.uk
What it does
Genome Analyzer is an agent skill from artwist-polyakov/polyakov-claude-skills. Анализирует генетические данные пользователя из VCF файла. Используй когда пользователь спрашивает о своей генетике, наследственных признаках, предрасположенностях, метаболизме веществ (кофеин, алкоголь, лекарства), спортивных способностях, рисках заболеваний, питании на основе генов.
Its SKILL.md is about 970 tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts.
It sits in Research & Science, covering Bioinformatics. The repository describes itself as: Набор скиллов для Claude. The licence is MIT.
When your agent uses it
- Tasks that involve Bioinformatics
Example prompts
- “/genome-analyzer”
What it can do on your machine
Read from SKILL.md and the folder at commit 8bbeead. It shows what the files ask for, not the result of running them.
Tool permissions
Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.
From allowed-tools in the SKILL.md frontmatter.
Runs code
No scripts in the folder and no shell commands in SKILL.md (its code samples are markdown).
From the folder's file list and the shell code blocks in SKILL.md.
Network
Hosts in commands or code, which the agent is likely to contact:
snpedia.comebi.ac.uk
From URLs in SKILL.md, links to its own repository left out.
Credentials
Names no API keys, tokens, secrets or passwords.
From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.
Context cost
Genome Analyzer loads about 966 tokens when it runs. Until then it costs about 75 tokens; SKILL.md has 265 words of instructions outside code blocks.
Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.
Safety
Auto-check passed
The automated check found no risky patterns in SKILL.md.
Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.
SKILL.md
The full file from artwist-polyakov/polyakov-claude-skills at commit 8bbeead, republished under its MIT licence (© artwist-polyakov). 265 words, ~966 tokens.
Download SKILL.mdSave it as
.claude/skills/genome-analyzer/SKILL.md (or your agent's skills folder).- name
- genome-analyzer
- description
- Анализирует генетические данные пользователя из VCF файла. Используй когда пользователь спрашивает о своей генетике, наследственных признаках, предрасположенностях, метаболизме веществ (кофеин, алкоголь, лекарства), спортивных способностях, рисках заболеваний, питании на основе генов.
Genome Analyzer
Ты анализируешь генетические данные пользователя из VCF файла.
VCF файл
VCF файл находится в текущей директории. Имя файла может быть любым (*.vcf).
Алгоритм работы
Шаг 0: Найти VCF файл
Используй Glob для поиска VCF файла в текущей директории:
pattern:*.vcf
Если найдено несколько файлов — спроси пользователя какой использовать. Если файл не найден — сообщи пользователю.
Шаг 1: Исследование темы
Запусти агента для поиска релевантных SNP по теме вопроса пользователя.
Используй Task tool с параметрами:
subagent_type: "general-purpose"model: "sonnet"prompt: Поиск SNP (rsID), связанных с темой вопроса
Агент должен:
- Использовать WebSearch для поиска генов и SNP по теме
- Искать в источниках: GWAS Catalog, SNPedia, научные статьи
- Вернуть список rsID с описанием эффектов каждого аллеля (risk/protective)
Шаг 2: Поиск в геноме
Используй Grep для поиска найденных rsID в VCF файле (путь из Шага 0):
pattern:rs123456|rs789012|rs...(объединить через |)path: путь к VCF файлу из Шага 0output_mode: "content"
Шаг 3: Интерпретация генотипов
Расшифруй генотипы из VCF:
0/0= гомозигота по референсу (REF/REF)0/1= гетерозигота (REF/ALT)1/1= гомозигота по альтернативе (ALT/ALT)
Сопоставь генотип с информацией об аллелях из Шага 1.
Формат ответа
ВАЖНО: Отчёт должен быть визуально привлекательным, структурированным и понятным. Используй эмодзи, таблицы, выделение текста.
Шаблон отчёта:
## [Эмодзи] [Тема анализа]
### Основные результаты
| SNP | Ген | Твой генотип | Риск | Интерпретация |
|-----|-----|--------------|------|---------------|
| rs1234567 | **GENE1** | A/G | ✅ Защитный | Краткое описание |
| rs7654321 | **GENE2** | T/T | ⚠️ Умеренный | Краткое описание |
| rs9999999 | **GENE3** | C/C | 🟢 Нейтральный | Краткое описание |
---
### 📊 Что это значит
**Твой профиль: [краткая характеристика в 3-5 слов]**
**Сильные стороны:**
- [Пункт 1 с объяснением]
- [Пункт 2 с объяснением]
**Зоны внимания:**
- [Пункт 1 — что это значит на практике]
- [Пункт 2 — что это значит на практике]
---
### 🎯 Практические рекомендации
1. **[Рекомендация 1]** — почему это важно с твоей генетикой
2. **[Рекомендация 2]** — конкретный совет
3. **[Рекомендация 3]** — что делать/не делать
---
### 📈 Итоговая оценка
| Аспект | Оценка |
|--------|--------|
| [Аспект 1] | 🟢 Низкий риск / ✅ Благоприятно |
| [Аспект 2] | 🟡 Умеренный |
| [Аспект 3] | 🔴 Повышенный риск |
---
### ⚠️ Дисклеймер
Генетика — это вероятности, не судьба. Окружающая среда, образ жизни и привычки часто важнее генов. Это информационный анализ, не медицинская консультация.
**Источники:** [SNPedia](https://snpedia.com), [GWAS Catalog](https://www.ebi.ac.uk/gwas/)Эмодзи для оформления
Заголовки по темам:
- 🏃 Спорт/фитнес
- ⚖️ Вес/ожирение
- 🧠 Зависимости/психика
- ☕ Кофеин
- 🍷 Алкоголь
- 🥛 Питание/непереносимости
- 💊 Лекарства
- ❤️ Сердце/сосуды
- 🧬 Общая генетика
Уровни риска в таблицах:
- ✅ Защитный/благоприятный
- 🟢 Нейтральный/стандартный
- 🟡 Умеренный риск
- ⚠️ Повышенное внимание
- 🔴 Высокий риск
Стиль написания
- Пиши простым языком, избегай научного жаргона
- Объясняй что означает каждый генотип НА ПРАКТИКЕ
- Давай конкретные, actionable рекомендации
- Используй жирный текст для выделения важного
- Разбивай текст на короткие абзацы
- Добавляй горизонтальные разделители
---между секциями - В таблицах используй эмодзи для визуального восприятия
© artwist-polyakov, MIT. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file
Files
Just SKILL.md in plugins/genome-analizer/skills/genome-analizer of artwist-polyakov/polyakov-claude-skills.
Open the folder on GitHubat commit 8bbeead
Compare with similar skills
Genome Analyzer next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.
| Skill | Stars | Used in | Tokens | Auto-check | Licence | Repo updated |
|---|---|---|---|---|---|---|
| Genome Analyzer this skillartwist-polyakov/polyakov-claude-skills | 208 | — | ~966 | Automated safety check: Pass | MIT | |
| Alphagenome Single Variant Analysisgoogle-deepmind/science-skills | 3.2k | 2 repos | ~3k | Automated safety check: Notes | Apache-2.0 | |
| 13C Metabolic Flux AnalysisK-Dense-AI/scientific-agent-skills | 48k | 1 repos | ~3.2k | Automated safety check: Pass | MIT | |
| Clinvar Databasegoogle-deepmind/science-skills | 3.2k | 2 repos | ~3.9k | Automated safety check: Notes | Apache-2.0 | |
| Metabolic Study Planneraiming-lab/AutoResearchClaw | 15k | — | ~1.9k | Automated safety check: Pass | MIT | |
| Dbsnp Databasegoogle-deepmind/science-skills | 3.2k | 2 repos | ~3.4k | Automated safety check: Notes | Apache-2.0 |
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Turns a broad metabolic modelling topic into a concrete, paper-shaped plan with organism, model, perturbations, metrics and figures before any FBA code is written.
Dbsnp Database
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MFA Pipeline Orchestrator
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Runs a metabolic flux analysis from model loading to phenotype prediction and figures by handing work to four sub-agents in sequence.
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Categories
Questions about Genome Analyzer
What does Genome Analyzer do?
Анализирует генетические данные пользователя из VCF файла. An agent skill from artwist-polyakov/polyakov-claude-skills. Genome Analyzer is an agent skill from artwist-polyakov/polyakov-claude-skills. Анализирует генетические данные пользователя из VCF файла.
When should I use Genome Analyzer?
Genome Analyzer fits situations like: tasks that involve Bioinformatics.
How do I install Genome Analyzer in Claude Code?
Run `npx skills add artwist-polyakov/polyakov-claude-skills --skill genome-analyzer -a claude-code`. Or copy the skill folder (plugins/genome-analizer/skills/genome-analizer in artwist-polyakov/polyakov-claude-skills) into .claude/skills/genome-analyzer in your project. Claude Code loads it when a task matches its description.
How do I install Genome Analyzer in Codex?
Run `npx skills add artwist-polyakov/polyakov-claude-skills --skill genome-analyzer -a codex`. Or copy the skill folder (plugins/genome-analizer/skills/genome-analizer in artwist-polyakov/polyakov-claude-skills) into .agents/skills/genome-analyzer in your project. Codex loads it when a task matches its description.
Can I use Genome Analyzer in Cursor, Gemini CLI or GitHub Copilot?
Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add artwist-polyakov/polyakov-claude-skills --skill genome-analyzer -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/genome-analyzer, .gemini/skills/genome-analyzer, .github/skills/genome-analyzer and .opencode/skills/genome-analyzer in your project.
What does Genome Analyzer need to run?
SKILL.md names no scripts, command-line tools or credentials: Genome Analyzer is instructions for the agent only.
Does Genome Analyzer access the network?
SKILL.md names 2 domains. In commands or code: snpedia.com and ebi.ac.uk; the agent is likely to contact these when it follows the instructions. This is read from the text; nothing was executed.
Is Genome Analyzer safe to install?
Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.
What licence does Genome Analyzer use?
Genome Analyzer is published under the MIT licence (the repository's licence). It allows redistribution, so the full SKILL.md is shown on this page.
How many tokens does Genome Analyzer use?
About 966 tokens (SKILL.md is roughly 3.9k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.
What are the alternatives to Genome Analyzer?
Skills that share tags, products or a category with Genome Analyzer: Alphagenome Single Variant Analysis (google-deepmind/science-skills, 3.2k stars), 13C Metabolic Flux Analysis (K-Dense-AI/scientific-agent-skills, 48k stars), Clinvar Database (google-deepmind/science-skills, 3.2k stars) and Metabolic Study Planner (aiming-lab/AutoResearchClaw, 15k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.
Who maintains Genome Analyzer?
artwist-polyakov (a GitHub user) maintains it in artwist-polyakov/polyakov-claude-skills, which has 208 GitHub stars. The repository holds 21 skills in this directory. The repository was last updated on October 8, 2026.
Source: artwist-polyakov/polyakov-claude-skills on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.